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  1. We previously identified and characterized a novel 55 kDa nuclear protein, termed nmt55/p54nrb, whose expression was decreased in a subset of human breast tumors. The objective of this study was to determine if t...

    Authors: Matthew Pavao, Yue-Hua Huang, Laurie J Hafer, Robert B Moreland and Abdulmaged M Traish
    Citation: BMC Cancer 2001 1:15
    Content type: Research article Published on:

  5. The role of telomerase activation in the expression and/or maintenance of drug resistance is not clearly understood. Therefore, we investigated the relationships, among the telomerase activity, telomere length...

    Authors: Noritsugu Kuranaga, Nariyoshi Shinomiya and Hidetaka Mochizuki
    Citation: BMC Cancer 2001 1:10
    Content type: Research article Published on:

  6. Loss of activity of tumor suppressor genes is considered a fundamental step in a genetic model of carcinogenesis. Altered expression of the p53 and the Deleted in Colon Cancer (DCC) proteins has been described...

    Authors: Francesco Graziano, Stefano Cascinu, Maria Pia Staccioli, Vincenzo Catalano, Maria Cristina Rossi, Anna Maria Baldelli, Paolo Giordani, Pietro Muretto and Giuseppina Catalano
    Citation: BMC Cancer 2001 1:9
    Content type: Research article Published on:

  7. The relationship between breast cancer and organochlorine exposure is controversial and complex. As estrogen receptor positive and negative breast cancer may represent different entities of the disease, this s...

    Authors: Annette P Høyer, Torben Jørgensen, Fritz Rank and Philippe Grandjean
    Citation: BMC Cancer 2001 1:8
    Content type: Research article Published on:

  8. Invasion and metastasis is a complex process governed by the interaction of genetically altered tumor cells and the immunological and inflammatory host reponse. Specific T-cells directed against tumor cells an...

    Authors: Iris D Nagtegaal, Corrie AM Marijnen, Elma Klein Kranenbarg, Adri Mulder-Stapel, Jo Hermans, Cornelis JH van de Velde and J Han JM van Krieken
    Citation: BMC Cancer 2001 1:7
    Content type: Research article Published on:

  9. Because cells progressing to cancer must proliferate, marker proteins specific to proliferating cells may permit detection of premalignant lesions. Here we compared the sensitivities of a classic proliferation...

    Authors: Dong-Feng Tan, Joel A Huberman, Andrew Hyland, Gregory M Loewen, John SJ Brooks, Amy F Beck, Ivan T Todorov and Gerold Bepler
    Citation: BMC Cancer 2001 1:6
    Content type: Research article Published on:

  10. A systematic review of the literature was carried out to determine the role of prophylactic cranial irradiation (PCI) in small cell lung cancer (SCLC) .

    Authors: Anne-Pascale Meert, Marianne Paesmans, Thierry Berghmans, Benoît Martin, Céline Mascaux, Frédéric Vallot, Jean-Marc Verdebout, Jean-Jacques Lafitte and Jean-Paul Sculier
    Citation: BMC Cancer 2001 1:5
    Content type: Research article Published on:

  11. Nasopharyngeal carcinoma (NPC) is a rare tumor in most parts of the world but occurs at relatively high frequency among people of Chinese descent. The cytochrome P450 2E1 enzyme (CYP2E1) is responsible for the...

    Authors: Narisorn Kongruttanachok, Sairoong Sukdikul, Surachai Setavarin, Verachai Kerekhjanarong, Pakpoom Supiyaphun, Narin Voravud, Yong Poovorawan and Apiwat Mutirangura
    Citation: BMC Cancer 2001 1:4
    Content type: Research article Published on:

  12. We assessed the nm23-H1 gene product expression and its relationship with lymphatic and blood vessel invasion in patients with esophageal squamous cell carcinoma.

    Authors: Masaki Tomita, Takanori Ayabe, Yasunori Matsuzaki, Masao Edagawa, Masayuki Maeda, Tetsuya Shimizu, Masaki Hara and Toshio Onitsuka
    Citation: BMC Cancer 2001 1:3
    Content type: Research article Published on:

  13. Human papillomavirus (HPV) is a crucial etiological factor for cervical cancer (CC) development. From a diagnostic view-point, the consistent presence of HPV in CC allows the viral DNA to be used as a genetic ...

    Authors: Wichai Pornthanakasem, Kanjana Shotelersuk, Wichai Termrungruanglert, Narin Voravud, Somchai Niruthisard and Apiwat Mutirangura
    Citation: BMC Cancer 2001 1:2
    Content type: Research article Published on:

  14. We investigated the chemopreventive action of dietary curcumin on 7,12-dimethylbenz(a)anthracene (DMBA)-initiated and 12,0-tetradecanoylphorbol-13-acetate (TPA)-promoted skin tumor formation in Swiss albino mi...

    Authors: Porn-ngarm Limtrakul, Songyot Anuchapreeda, Suwiwek Lipigorngoson and Floyd W Dunn
    Citation: BMC Cancer 2001 1:1
    Content type: Research article Published on:

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