Skip to main content

Articles

Page 213 of 228

  1. Gefitinib, an oral agent of epidermal growth factor receptor tyrosine kinase inhibitor, has a certain efficacy against non-small cell lung cancer (NSCLC). Several predictive factors of gefitinib sensitivity ha...

    Authors: Hiroshi Yokouchi, Koichi Yamazaki, Ichiro Kinoshita, Jun Konishi, Hajime Asahina, Noriaki Sukoh, Masao Harada, Kenji Akie, Shigeaki Ogura, Takashi Ishida, Mitsuru Munakata, Hirotoshi Dosaka-Akita, Hiroshi Isobe and Masaharu Nishimura

    Citation: BMC Cancer 2007 7:51

    Content type: Research article

    Published on:

  2. After two studies reporting response rates higher than 70% in HER2-positive metastatic breast cancer with weekly trastuzumab and vinorelbine, we planned a phase 2 study to test activity of the same combination...

    Authors: Ermelinda De Maio, Carmen Pacilio, Adriano Gravina, Alessandro Morabito, Francesca Di Rella, Vincenzo Labonia, Gabriella Landi, Francesco Nuzzo, Emanuela Rossi, Pasqualina Silvestro, Gerardo Botti, Maurizio Di Bonito, Maria Pia Curcio, Franca Formichelli, Franca La Vecchia, Maria Staiano…

    Citation: BMC Cancer 2007 7:50

    Content type: Research article

    Published on:

  3. As chondrosarcomas are resistant to chemotherapy and ionizing radiation, therapeutic options are limited. Radical surgery often cannot be performed. Therefore, additional therapies such as antiangiogenesis rep...

    Authors: Frank M Klenke, Amir Abdollahi, Elisabeth Bertl, Martha-Maria Gebhard, Volker Ewerbeck, Peter E Huber and Axel Sckell

    Citation: BMC Cancer 2007 7:49

    Content type: Research article

    Published on:

  4. Lung cancer (LC) is the leading cause of cancer-related deaths. Oxidative DNA damage may contribute to the cancer risk. The antioxidant paraoxonase (PON1) is an endogenous free radical scavenger in the human b...

    Authors: Emin T Elkiran, Nefsal Mar, Bilge Aygen, Ferit Gursu, Aziz Karaoglu and Suleyman Koca

    Citation: BMC Cancer 2007 7:48

    Content type: Research article

    Published on:

  5. High risk type human papilloma viruses (HR-HPV) induce carcinomas of the uterine cervix by expressing viral oncogenes E6 and E7. Oncogene E7 of HR-HPV disrupts the pRb/E2F interaction, which negatively regulat...

    Authors: Tatiana A Ivanova, Daria A Golovina, Larisa E Zavalishina, Galina M Volgareva, Alexey N Katargin, Yulia Y Andreeva, Georgy A Frank, Fjodor L Kisseljov and Natalia P Kisseljova

    Citation: BMC Cancer 2007 7:47

    Content type: Research article

    Published on:

  6. IL-1beta has been implicated in inflammatory episode. In view of the inflammatory nature of cancer cachexia, we determined the predictive value of IL-1B-31 T/C, -511 C/T, +3954 C/T and IL-1RN VNTR gene polymor...

    Authors: Dianliang Zhang, Hongmei Zheng, Yanbing Zhou, Xingming Tang, Baojun Yu and Jieshou Li

    Citation: BMC Cancer 2007 7:45

    Content type: Research article

    Published on:

  7. Breast cancer is one of the most extensively studied cancers and its genetic basis is well established. Dermatoglyphic traits are formed under genetic control early in development but may be affected by enviro...

    Authors: Chintamani, Rohan Khandelwal, Aliza Mittal, Sai Saijanani, Amita Tuteja, Anju Bansal, Dinesh Bhatnagar and Sunita Saxena

    Citation: BMC Cancer 2007 7:44

    Content type: Research article

    Published on:

  8. Cancer-cachexia induces a variety of metabolic disorders on protein turnorver, decreasing protein synthesis and increasing protein degradation. Controversly, insulin, other hormones, and branched-chain amino a...

    Authors: Gislaine Ventrucci, Maria Alice R Mello and Maria Cristina C Gomes-Marcondes

    Citation: BMC Cancer 2007 7:42

    Content type: Research article

    Published on:

  9. The disappointing results of surgical therapy alone of ductal pancreatic cancer can only be improved using multimodal approaches. In contrast to adjuvant therapy, neoadjuvant chemoradiation is able to facilita...

    Authors: Thomas B Brunner, Gerhard G Grabenbauer, Thomas Meyer, Henriette Golcher, Rolf Sauer and Werner Hohenberger

    Citation: BMC Cancer 2007 7:41

    Content type: Study protocol

    Published on:

  10. The study was designed to investigate immunocompetence in relation to cancer progression in rat and to assess the effect of the traditional Chinese anti-cancer medicine, "Shenyang" prescription, on immunity.

    Authors: Canhua Jiang, Dongxia Ye, Weiliu Qiu, Xiuli Zhang, Zhiyuan Zhang, Di He, Ping Zhang and Wantao Chen

    Citation: BMC Cancer 2007 7:40

    Content type: Research article

    Published on:

  11. Current histo-pathological prognostic factors are not very helpful in predicting the clinical outcome of breast cancer due to the disease's heterogeneity. Molecular profiling using a large panel of genes could...

    Authors: Maïa Chanrion, Hélène Fontaine, Carmen Rodriguez, Vincent Negre, Frédéric Bibeau, Charles Theillet, Alain Hénaut and Jean-Marie Darbon

    Citation: BMC Cancer 2007 7:39

    Content type: Research article

    Published on:

  12. Primary small cell carcinoma (SCC) of the esophagus is a rare and aggressive tumor with poor prognosis. In this study, we report the clinicopathological characteristics of 21 cases of small cell carcinoma of t...

    Authors: Jing-Ping Yun, Mei-Fang Zhang, Jin-Hui Hou, Qiu-Hong Tian, Jia Fu, Xiao-Man Liang, Qiu-Liang Wu and Tie-Hua Rong

    Citation: BMC Cancer 2007 7:38

    Content type: Research article

    Published on:

  13. Shared Pathology Informatics Network (SPIN) is a tissue resource initiative that utilizes clinical reports of the vast amount of paraffin-embedded tissues routinely stored by medical centers. SPIN has an infor...

    Authors: Ashokkumar A Patel, Dilipkumar Gupta, David Seligson, Eyas M Hattab, Ulysses J Balis, Thomas M Ulbright, Isaac S Kohane, Jules J Berman, John R Gilbertson, Sarah Dry, Osvaldo Schirripa, Hong Yu, Michael J Becich and Anil V Parwani

    Citation: BMC Cancer 2007 7:37

    Content type: Research article

    Published on:

  14. Neoadjuvant chemotherapy has been considered the standard care in locally advanced breast cancer. However, about 20% of the patients do not benefit from this clinical treatment and, predictive factors of respo...

    Authors: Daniel G Tiezzi, Jurandyr M Andrade, Alfredo Ribeiro-Silva, Fábio E Zola, Heitor RC Marana and Marcelo G Tiezzi

    Citation: BMC Cancer 2007 7:36

    Content type: Research article

    Published on:

  15. The inability of cancer cells to present antigen on the cell surface via MHC class I molecules is one of the mechanisms by which tumor cells evade anti-tumor immunity. Alterations of Jak-STAT components of int...

    Authors: Teresa Rodríguez, Rosa Méndez, Ana Del Campo, Pilar Jiménez, Natalia Aptsiauri, Federico Garrido and Francisco Ruiz-Cabello

    Citation: BMC Cancer 2007 7:34

    Content type: Research article

    Published on:

  16. Abnormalities in Human Leukocyte Antigen (HLA) class I expression are common in colorectal cancer. Since HLA expression is required to activate tumor antigen-specific cytotoxic T-lymphocytes (CTL), HLA class I...

    Authors: Jan Willem F Dierssen, Noel FCC de Miranda, Soldano Ferrone, Marjo van Puijenbroek, Cees J Cornelisse, Gert Jan Fleuren, Tom van Wezel and Hans Morreau

    Citation: BMC Cancer 2007 7:33

    Content type: Research article

    Published on:

  17. In general, prognosis and impact of prognostic/predictive factors are assessed with Kaplan-Meier plots and/or the Cox proportional hazard model. There might be substantive differences from the results using th...

    Authors: Patricia Tai, Judith-Anne W Chapman, Edward Yu, Dennie Jones, Changhong Yu, Fei Yuan and Lee Sang-Joon

    Citation: BMC Cancer 2007 7:31

    Content type: Research article

    Published on:

  18. The STAT (Signal Transducers and Activators of Transcription) transcription factor family mediates cellular responses to a wide range of cytokines. Activated STATs (particularly STAT3) are found in a range of ...

    Authors: James R Matthews, Susan MR Watson, Maxine CL Tevendale, Christine J Watson and Alan R Clarke

    Citation: BMC Cancer 2007 7:29

    Content type: Research article

    Published on:

  19. Hepatocellular carcinoma is the most common cause of primary liver neoplasms and is one of the main causes of death in patients with liver cirrhosis. High Alpha fetoprotein serum levels have been found in 60–7...

    Authors: Oscar Arrieta, Bernardo Cacho, Daniela Morales-Espinosa, Ana Ruelas-Villavicencio, Diana Flores-Estrada and Norma Hernández-Pedro

    Citation: BMC Cancer 2007 7:28

    Content type: Research article

    Published on:

  20. Authors: Vanessa Rosas-Camargo, José Luis Rodríguez-Díaz, Olynka Vega-Vega, Aniela Méndez-Reguera, Daniela Morales Espinosa, Jorge Luis Martínez-Tlahuel, Armando Gamboa-Domínguez and Oscar Arrieta

    Citation: BMC Cancer 2007 7(Suppl 1):A33

    Content type: Meeting abstract

    Published on:

    This article is part of a Supplement: Volume 7 Supplement 1

  21. Authors: Myrna Candelaria, Dolores Gallardo-Rincón, Claudia Arce, Lucely Cetina, Jose Luis Aguilar-Ponce, Oscar Arrieta, Alberto Serrano, Carlos Perez-Plasencia, Aurora Gonzalez-Fierro, Erik de la Cruz-Hernandez, Alma Revilla-Vazquez, Alma Chavez-Blanco, Catalina Trejo-Becerril, Enrique Perez-Cardenas, Lucia Taja-Chayeb, Maria F Camargo…

    Citation: BMC Cancer 2007 7(Suppl 1):A27

    Content type: Meeting abstract

    Published on:

    This article is part of a Supplement: Volume 7 Supplement 1

  22. Authors: Claudia Arce, Carlos Perez-Plasencia, Aurora Gonzalez-Fierro, Erik de la Cruz-Hernandez, Alma Revilla-Vazquez, Alma Chavez-Blanco, Catalina Trejo-Becerril, Enrique Perez-Cardenas, Lucia Taja-Chayeb, Enrique Bargallo, Patricia Villarreal, Teresa Ramirez, Teresa Vela, Myrna Candelaria, Maria F Camargo, Elizabeth Robles…

    Citation: BMC Cancer 2007 7(Suppl 1):A23

    Content type: Meeting abstract

    Published on:

    This article is part of a Supplement: Volume 7 Supplement 1

  23. Authors: Lucely Cetina, Alicia Garcia, Jesús Uribe, Myrna Candelaria, Carlos Lopez-Graniel, Aaron Gonzalez, David Cantu, Lesbia Rivera, Jose Hinojosa and Alfonso Dueñas-Gonzalez

    Citation: BMC Cancer 2007 7(Suppl 1):A19

    Content type: Meeting abstract

    Published on:

    This article is part of a Supplement: Volume 7 Supplement 1

  24. Authors: Lucely Cetina, Alicia Garcia-Arias, Maria de Jesus Uribe, Alma Astorga, Myrna Candelaria, Aida Mota, Roque Guadarrama, Lesbia Rivera, Jose Hinojosa and Alfonso Dueñas-Gonzalez

    Citation: BMC Cancer 2007 7(Suppl 1):A17

    Content type: Meeting abstract

    Published on:

    This article is part of a Supplement: Volume 7 Supplement 1

Featured videos

View featured videos from across the BMC-series journals