Skip to main content

Articles

Page 194 of 327

  1. Lymphangioleiomyomatosis (LAM) is a rare idiopathic disorder that occurs in women of childbearing age, and consists of a diffuse proliferation of abnormal smooth muscle cells along the thoracic and abdominal l...

    Authors: Kensuke Suzuki, Kazunori Nagasaka, Katsutoshi Oda, Hiroyuki Abe, Daichi Maeda, Yoko Matsumoto, Takahide Arimoto, Kei Kawana, Masashi Fukayama, Yutaka Osuga and Tomoyuki Fujii
    Citation: BMC Cancer 2016 16:390
  2. The incidence of lung cancer in many parts of the country as shown in cancer registry statistics is not decreasing. The incidence of adenocarcinoma (ADCA) in Songkhla is now higher than that of squamous cell c...

    Authors: Hutcha Sriplung, Seesai Yeesoonsang, Edward McNeil and Surichai Bilheem
    Citation: BMC Cancer 2016 16:389
  3. Meprin displays multiple functions in both health and disease, due in part to its broad proteolytic activity. In this report, we explored the clinical significance and functional relevance of the expression of...

    Authors: Xiao Wang, Jian Chen, Jingtao Wang, Fudong Yu, Senlin Zhao, Yu Zhang, Huamei Tang and Zhihai Peng
    Citation: BMC Cancer 2016 16:383

    The Correction to this article has been published in BMC Cancer 2018 18:70

  4. Better insights into the molecular changes involved in virus-associated and -independent head and neck cancer may advance our knowledge of HNC carcinogenesis and identify critical disease biomarkers. Here we a...

    Authors: Zuzana Vojtechova, Ivan Sabol, Martina Salakova, Jana Smahelova, Jiri Zavadil, Lubomir Turek, Marek Grega, Jan Klozar, Bohumir Prochazka and Ruth Tachezy
    Citation: BMC Cancer 2016 16:382
  5. Transanal total mesorectal excision (taTME) is an emerging surgical technique for rectal cancer. However, the oncological and perioperative outcomes are controversial when compared with conventional laparoscop...

    Authors: Bin Ma, Peng Gao, Yongxi Song, Cong Zhang, Changwang Zhang, Longyi Wang, Hongpeng Liu and Zhenning Wang
    Citation: BMC Cancer 2016 16:380
  6. Aberrant expression of microRNAs has been associated with migration of tumor cells. In this study, we aimed to investigate the biological significance of miR-944 whose function is unknown in breast cancer.

    Authors: Ali Flores-Pérez, Laurence A. Marchat, Sergio Rodríguez-Cuevas, Verónica Piña Bautista, Lizeth Fuentes-Mera, Diana Romero-Zamora, Anabel Maciel-Dominguez, Olga Hernández de la Cruz, Miguel Fonseca-Sánchez, Erika Ruíz-García, Horacio Astudillo-de la Vega and César López-Camarillo
    Citation: BMC Cancer 2016 16:379
  7. The estrogen receptor (ER) inhibitor tamoxifen reduces breast cancer mortality by 31 % and has served as the standard treatment for ER-positive breast cancers for decades. However, 50 % of advanced ER-positive...

    Authors: Sara Kangaspeska, Susanne Hultsch, Alok Jaiswal, Henrik Edgren, John-Patrick Mpindi, Samuli Eldfors, Oscar Brück, Tero Aittokallio and Olli Kallioniemi
    Citation: BMC Cancer 2016 16:378
  8. Expression of the androgen receptor (AR) is associated with androgen-dependent proliferation arrest and terminal differentiation of normal prostate epithelial cells. Additionally, activation of the AR is requi...

    Authors: Jan Roger Olsen, Waqas Azeem, Margrete Reime Hellem, Kristo Marvyin, Yaping Hua, Yi Qu, Lisha Li, Biaoyang Lin, XI-Song Ke, Anne Margrete Øyan and Karl-Henning Kalland
    Citation: BMC Cancer 2016 16:377
  9. Male breast cancer (MBC) is rare. Given the paucity of randomized trials, treatment is generally extrapolated from female breast cancer guidelines.

    Authors: Piera Gargiulo, Matilde Pensabene, Monica Milano, Grazia Arpino, Mario Giuliano, Valeria Forestieri, Caterina Condello, Rossella Lauria and Sabino De Placido
    Citation: BMC Cancer 2016 16:375
  10. Every year 170,000 patients are diagnosed with brain metastases (BMs) in the United States. Traditionally, adjuvant whole brain radiotherapy (AWBRT) has been offered following local therapy with neurosurgery (...

    Authors: Gerald B. Fogarty, Angela Hong, Vinai Gondi, Bryan Burmeister, Kari Jacobsen, Serigne Lo, Elizabeth Paton, Brindha Shivalingam and John F. Thompson
    Citation: BMC Cancer 2016 16:372
  11. Gastric cancer is the fourth most common cancer and the second most deadly cancer worldwide. Study on molecular mechanisms of carcinogenesis will play a significant role in diagnosing and treating gastric canc...

    Authors: Huijuan Wang, Hailong Zhang, Pengchi Deng, Chunqi Liu, Dandan Li, Hui Jie, Hu Zhang, Zongguang Zhou and Ying-Lan Zhao
    Citation: BMC Cancer 2016 16:371
  12. African American (AA) colon cancer patients have a worse prognosis than Caucasian (CA) colon cancer patients, however, reasons for this disparity are not well understood. To determine if tumor biology might co...

    Authors: Rangaswamy Govindarajan, James Posey, Calvin Y. Chao, Ruixiao Lu, Trafina Jadhav, Ahmed Y. Javed, Awais Javed, Fade A. Mahmoud, Raymond U. Osarogiagbon and Upender Manne
    Citation: BMC Cancer 2016 16:368
  13. Human papillomavirus DNA detection in head and neck squamous cell carcinoma has been linked to improved patient prognosis. The main aims of the study was to test the hypotheses that HPV16 E6/E7 oncogene and p5...

    Authors: Liam Masterson, David M. Winder, Siolian L. R. Ball, Katie Vaughan, Martin Lehmann, Lars-Uwe Scholtz, Jane C. Sterling, Holger H. Sudhoff and Peter K. C. Goon
    Citation: BMC Cancer 2016 16:367
  14. Several recent studies have reported that patients with metastatic colorectal cancer (CRC) whose primary tumor is located in left side of the colon have more favorable responses to anti-epidermal growth factor...

    Authors: Hidekazu Kuramochi, Ayako Nakamura, Go Nakajima, Yuka Kaneko, Tatsuo Araida, Masakazu Yamamoto and Kazuhiko Hayashi
    Citation: BMC Cancer 2016 16:366
  15. Cornelia de Lange syndrome is the prototype for cohesinopathy disorders, which are characterized by defects in chromosome segregation. Kidney malformations, including nephrogenic rests, are common in Cornelia ...

    Authors: Claudia Santoro, Andrea Apicella, Fiorina Casale, Angela La Manna, Martina Di Martino, Daniela Di Pinto, Cristiana Indolfi and Silverio Perrotta
    Citation: BMC Cancer 2016 16:365
  16. For patients with metastatic renal cell carcinoma (mRCC), targeted therapies have entered the market since 2006. The aims of this study were to evaluate the uptake and use of targeted therapies for mRCC in The...

    Authors: S. De Groot, S. Sleijfer, W. K. Redekop, E. Oosterwijk, J. B. A. G. Haanen, L. A. L. M. Kiemeney and C. A. Uyl-de Groot
    Citation: BMC Cancer 2016 16:364
  17. Primary diffuse large B-cell lymphoma of the central nervous system (PCNS-DLBCL) is a distinct clinicopathological entity with a poor prognosis. Concurrent MYC and BCL2 overexpression predicts inferior prognos...

    Authors: Sehui Kim, Soo Jeong Nam, Dohee Kwon, Hannah Kim, Eunyoung Lee, Tae Min Kim, Dae Seog Heo, Sung Hye Park, Chul Woo Kim and Yoon Kyung Jeon
    Citation: BMC Cancer 2016 16:363
  18. To assess the impact of volumetric-modulated arc therapy (VMAT) compared with 3D-conformal radiotherapy (3DCRT) in patients with newly diagnosed high grade glioma in terms of toxicity, progression free surviva...

    Authors: Pierina Navarria, Federico Pessina, Luca Cozzi, Anna Maria Ascolese, Francesca Lobefalo, Antonella Stravato, Giuseppe D’Agostino, Ciro Franzese, Manuela Caroli, Lorenzo Bello and Marta Scorsetti
    Citation: BMC Cancer 2016 16:362
  19. Some triple negative breast cancer (TNBC) patients are at higher risk of recurrence in the first three years after treatment. This rapid relapse has been suggested to be associated with inflammatory mediators ...

    Authors: Gina Bouchard, Hélène Therriault, Sameh Geha, Yves Bérubé-Lauzière, Rachel Bujold, Caroline Saucier and Benoit Paquette
    Citation: BMC Cancer 2016 16:361
  20. Short-term starvation prior to chemotherapy administration protects mice against toxicity. We undertook dose-escalation of fasting prior to platinum-based chemotherapy to determine safety and feasibility in ca...

    Authors: Tanya B. Dorff, Susan Groshen, Agustin Garcia, Manali Shah, Denice Tsao-Wei, Huyen Pham, Chia-Wei Cheng, Sebastian Brandhorst, Pinchas Cohen, Min Wei, Valter Longo and David I. Quinn
    Citation: BMC Cancer 2016 16:360
  21. Osteopontin is a secreted phosphoglycoprotein that is expressed by a number of normal cells as well as a variety of tumor cells. With respect to breast cancer, osteopontin has been implicated in regulating tum...

    Authors: S. Saleh, D. E. Thompson, J. McConkey, P. Murray and R. A. Moorehead
    Citation: BMC Cancer 2016 16:359
  22. Serine/arginine-rich splicing factors (SRSFs) and HNRNPA1 have oncogenic properties. However, their proteomic expressions and practical priority in gastric cancer (GC) and colorectal cancer (CRC) are mostly un...

    Authors: Won Cheol Park, Hak-Ryul Kim, Dong Baek Kang, Jae-Suk Ryu, Keum-Ha Choi, Gyeong-Ok Lee, Ki Jung Yun, Keun Young Kim, Raekil Park, Kwon-Ha Yoon, Ji-Hyun Cho, Young-Jin Lee, Soo-Cheon Chae, Min-Cheol Park and Do-Sim Park
    Citation: BMC Cancer 2016 16:358
  23. Patients with primary and metastatic liver malignancies represent a highly heterogeneous patient pool characterised by some of the shortest life expectancies amongst oncology patients. Investigation and better...

    Authors: Olga Golubnitschaja, Kristina Yeghiazaryan, Helena Stricker, Daniela Trog, Hans H. Schild and Leonard Berliner
    Citation: BMC Cancer 2016 16:357
  24. Delay in the diagnosis of breast cancer in symptomatic women of 3 months or more is associated with advanced stage and low survival. We conducted this study to learn more about the extent and reasons behind di...

    Authors: A. Maghous, F. Rais, S. Ahid, N. Benhmidou, K. Bellahamou, H. Loughlimi, E. Marnouche, S. Elmajjaoui, H. Elkacemi, T. Kebdani and N. Benjaafar
    Citation: BMC Cancer 2016 16:356
  25. TFEB (transcription factor EB) regulates metabolic homeostasis through its activation of lysosomal biogenesis following its nuclear translocation. TFEB activity is inhibited by mTOR phosphorylation, which sign...

    Authors: Paula Andrea Marin Zapata, Carsten Jörn Beese, Anja Jünger, Giovanni Dalmasso, Nathan Ryan Brady and Anne Hamacher-Brady
    Citation: BMC Cancer 2016 16:355
  26. It has been shown that epidermal growth factor receptor (EGFR) mutation status is associated with 5-fluorouracil (5-FU) sensitivity in non-small-cell lung cancer (NSCLC). However, the relationship between EGFR...

    Authors: Tetsuro Tominaga, Tomoshi Tsuchiya, Koji Mochinaga, Junichi Arai, Naoya Yamasaki, Keitaro Matsumoto, Takuro Miyazaki, Toshiya Nagasaki, Atsushi Nanashima, Kazuhiro Tsukamoto and Takeshi Nagayasu
    Citation: BMC Cancer 2016 16:354
  27. Cholangiocarcinoma is characterized by late diagnosis and a poor survival rate. MicroRNAs have been involved in the pathogenesis of different cancer types, including cholangiocarcinoma. Our aim was to identify...

    Authors: Tiziana Palumbo, George A. Poultsides, Grigorios Kouraklis, Theodore Liakakos, Alexandra Drakaki, George Peros, Maria Hatziapostolou and Dimitrios Iliopoulos
    Citation: BMC Cancer 2016 16:353
  28. Human epidermal growth factor receptor 2 (HER2)-positive breast cancer is a particularly aggressive form of the disease, and ultimately progresses in patients with metastases on standard therapies. Anthracycli...

    Authors: Kathy Miller, Javier Cortes, Sara A. Hurvitz, Ian E. Krop, Debu Tripathy, Sunil Verma, Kaveh Riahi, Joseph G. Reynolds, Thomas J. Wickham, Istvan Molnar and Denise A. Yardley
    Citation: BMC Cancer 2016 16:352
  29. We adapted Bayesian statistical learning strategies to the prognosis field to investigate if genome-wide common SNP improve the prediction ability of clinico-pathological prognosticators and applied it to non-...

    Authors: E. López de Maturana, A. Picornell, A. Masson-Lecomte, M. Kogevinas, M. Márquez, A. Carrato, A. Tardón, J. Lloreta, M. García-Closas, D. Silverman, N. Rothman, S. Chanock, F. X. Real, M. E. Goddard and N. Malats
    Citation: BMC Cancer 2016 16:351
  30. Early detection of oral squamous cell carcinomas (OSCCs) is urgently needed to improve the prognosis and quality of life (QOL) of patients. Oral leukoplakias (OLs), known as the most common premalignant lesion...

    Authors: Masanobu Abe, Satoshi Yamashita, Yoshiyuki Mori, Takahiro Abe, Hideto Saijo, Kazuto Hoshi, Toshikazu Ushijima and Tsuyoshi Takato
    Citation: BMC Cancer 2016 16:350
  31. Dietary methionine restriction (MR) improves healthspan in part by reducing adiposity and by increasing insulin sensitivity in rodent models. The purpose of this study was to determine whether MR inhibits tumo...

    Authors: J. R. Hens, I. Sinha, F. Perodin, T. Cooper, R. Sinha, J. Plummer, C. E. Perrone and D. Orentreich
    Citation: BMC Cancer 2016 16:349

    The Erratum to this article has been published in BMC Cancer 2016 16:474

  32. Radical treatment for oligometastatic non-small-cell lung cancer (NSCLC) has a curative potential for selected patients. The present retrospective study was designed to examine the relevance of synchronous vs....

    Authors: Jochen Fleckenstein, Alev Petroff, Hans-Joachim Schäfers, Thomas Wehler, Jakob Schöpe and Christian Rübe
    Citation: BMC Cancer 2016 16:348
  33. The objective of our study was to investigate the clinical characteristics and prognosis of postterm choriocarcinoma patients at Peking Union Medical College Hospital within the past 30 years.

    Authors: Jie Li, Junjun Yang, Pengfei Liu, Tong Ren, Jun Zhao, Fengzhi Feng, Xirun Wan and Yang Xiang
    Citation: BMC Cancer 2016 16:347
  34. Thailand has a high incidence of cholangiocarcinoma (CCA), particularly in the north and northeastern regions. Most CCA patients come at a late, unresectable stage and presently no optimal screening test for C...

    Authors: Prakongboon Sungkasubun, Surachate Siripongsakun, Kunlayanee Akkarachinorate, Sirachat Vidhyarkorn, Akeanong Worakitsitisatorn, Thaniya Sricharunrat, Sutida Singharuksa, Rawisak Chanwat, Chairat Bunchaliew, Sirima Charoenphattharaphesat, Ruechuta Molek, Maneenop Yimyaem, Gaidganok Sornsamdang, Kamonwan Soonklang, Kasiruck Wittayasak, Chirayu U. Auewarakul…
    Citation: BMC Cancer 2016 16:346
  35. The Her2 receptor is overexpressed in up to 25 % of breast cancers and is associated with a poor prognosis. Around half of Her2+ breast cancers also express the estrogen receptor and treatment for such tumours...

    Authors: Sharath Gangadhara, Chris Smith, Peter Barrett-Lee and Stephen Hiscox
    Citation: BMC Cancer 2016 16:345
  36. Breast cancer screening in the Basque Country has shown 20 % reduction of the number of BC deaths and an acceptable overdiagnosis level (4 % of screen detected BC). The aim of this study was to evaluate the br...

    Authors: Arantzazu Arrospide, Montserrat Rue, Nicolien T. van Ravesteyn, Merce Comas, Myriam Soto-Gordoa, Garbiñe Sarriugarte and Javier Mar
    Citation: BMC Cancer 2016 16:344
  37. L-Arg is involved in many biological activities, including the activation of T cells. In breast cancer patients, L-Arg is depleted by nitric oxide synthase 2 (NOS2) and arginase 1 (ARG-1) produced by myeloid-d...

    Authors: Yu Cao, Yonghui Feng, Yanjun Zhang, Xiaotong Zhu and Feng Jin
    Citation: BMC Cancer 2016 16:343
  38. Studies of human polyomavirus (HPyV) infection and lung cancer are limited and those regarding the association of human papillomavirus (HPV) infection and lung cancer have produced inconsistent results.

    Authors: Danny V. Colombara, Lisa E. Manhart, Joseph J. Carter, Stephen E. Hawes, Noel S. Weiss, James P. Hughes, You-Lin Qiao, Philip R. Taylor, Jennifer S. Smith and Denise A. Galloway
    Citation: BMC Cancer 2016 16:342
  39. Tissue Factor (TF) forms a proteolytically active complex together with coagulation factor VIIa (FVIIa) and functions as the trigger of blood coagulation or alternatively activates cell signaling. We recently ...

    Authors: Oskar Eriksson, Ã…sa Thulin, Anna Asplund, Geeta Hegde, Sanjay Navani and Agneta Siegbahn
    Citation: BMC Cancer 2016 16:341
  40. Along with the marked increase in early gastric cancer (EGC) in the Eastern countries, there has been an effort to adopt the sentinel node concept in EGC to preserve gastric function and reduce the occurrence ...

    Authors: Ji Yeon Park, Young-Woo Kim, Keun Won Ryu, Byung-Ho Nam, Young Joon Lee, Sang Ho Jeong, Ji-Ho Park, Hoon Hur, Sang-Uk Han, Jae Seok Min, Ji Yeong An, Woo Jin Hyung, Gyu Seok Cho, Gui Ae Jeong, Oh Jeong, Young Kyu Park…
    Citation: BMC Cancer 2016 16:340
  41. Patients with metastatic colorectal cancer whose disease has progressed on oxaliplatin- and irinotecan-containing regimens may benefit from EGFR-inhibiting monoclonal antibodies if they do not contain mutation...

    Authors: Eva Segelov, Paul Waring, Jayesh Desai, Kate Wilson, Val Gebski, Subotheni Thavaneswaran, Elena Elez, Craig Underhill, Nick Pavlakis, Lorraine Chantrill, Louise Nott, Michael Jefford, Mustafa Khasraw, Fiona Day, Harpreet Wasan, Fortunato Ciardiello…
    Citation: BMC Cancer 2016 16:339
  42. We investigated the contribution of subsequent therapy for advanced hepatocellular carcinoma refractory or intolerant to sorafenib. Further, we investigated the impact of sorafenib on overall survival using in...

    Authors: Takeshi Terashima, Tatsuya Yamashita, Rika Horii, Kuniaki Arai, Kazunori Kawaguchi, Kazuya Kitamura, Taro Yamashita, Yoshio Sakai, Eishiro Mizukoshi, Masao Honda and Shuichi Kaneko
    Citation: BMC Cancer 2016 16:338
  43. Because inheritance is recognized as playing a role in age at menarche and natural menopause, the development of chemotherapy-induced amenorrhea (CIA) might depend on inherited genetic factors; however, studie...

    Authors: Toralf Reimer, Sarah Kempert, Bernd Gerber, Hans-Jürgen Thiesen, Steffi Hartmann and Dirk Koczan
    Citation: BMC Cancer 2016 16:337
  44. Studies over the past decade and half have identified cancer stem cells (CSCs) to be responsible for tumorigenesis, invasion, sustenance of metastatic disease, radio- and chemo-resistance and tumor relapse. Re...

    Authors: Veena Somasundaram, Sreelatha K Hemalatha, Krishnendu Pal, Sutapa Sinha, Asha S. Nair, Debabrata Mukhopadhyay and Priya Srinivas
    Citation: BMC Cancer 2016 16:336
  45. Perturbed genotypes in cancer can now be identified by whole genome sequencing of large number of diverse tumor samples, and observed gene mutations can be used for prognosis and classification of cancer subty...

    Authors: Sarah Daakour, Leon Juvenal Hajingabo, Despoina Kerselidou, Aurelie Devresse, Richard Kettmann, Nicolas Simonis, Franck Dequiedt and Jean-Claude Twizere
    Citation: BMC Cancer 2016 16:335
  46. To assess the importance of heredity in the etiology of inflammatory breast cancer (IBC), we compared IBC patients to several carefully chosen comparison groups with respect to the prevalence of first-degree f...

    Authors: Roxana Moslehi, Elizabeth Freedman, Nur Zeinomar, Carmela Veneroso and Paul H. Levine
    Citation: BMC Cancer 2016 16:334

Featured videos

View featured videos from across the BMC-series journals