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Survivorship

This section focuses on research related to post-treatment cancer survivors. Topics of interest include, but are not limited to, long-term studies on adverse events/side effects of cancer treatment, mortality of young cancer survivors, policy-related research that can impact the quality of care and quality of life of cancer survivors, recent guidelines for investigation of complications after treatment in child and adult cancers.

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  1. Liver fibrosis or cirrhosis is associated with the dismal prognosis of hepatocellular carcinoma (HCC), and it might also be involved in intrahepatic cholangiocarcinoma (ICC). The effect of hepatic fibrosis on ...

    Authors: Jian Xi Zhang, Peipei Li, Zhibin Chen, Huogui Lin, Zhezhen Cai, Weijia Liao and Zirong Pan

    Citation: BMC Cancer 2020 20:556

    Content type: Research article

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  2. Multiple Myeloma (MM) is a cancer characterised by the proliferation of malignant plasma cells in the bone marrow. This study examined the treatment preferences of people living with MM compared to the treatme...

    Authors: Simon J. Fifer, Kerrie-Anne Ho, Sean Lybrand, Laurie J. Axford and Steve Roach

    Citation: BMC Cancer 2020 20:546

    Content type: Research article

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  3. Advances in peri-operative care of surgical oncology patients result in shorter hospital stays. Earlier discharge may bring benefits, but complications can occur while patients are recovering at home. Electron...

    Authors: H. S. Richards, J. M. Blazeby, A. Portal, R. Harding, T. Reed, T. Lander, K. A. Chalmers, R. Carter, R. Singhal, K. Absolom, G. Velikova and K. N. L. Avery

    Citation: BMC Cancer 2020 20:543

    Content type: Research article

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  4. Financial toxicity of cancer has so far been discussed primarily in the US health care system and is associated with higher morbidity and mortality. In European health care systems, the socio-economic impact o...

    Authors: Katja Mehlis, Julian Witte, Bastian Surmann, Matthias Kudlich, Leonidas Apostolidis, Jürgen Walther, Dirk Jäger, Wolfgang Greiner and Eva C. Winkler

    Citation: BMC Cancer 2020 20:529

    Content type: Research article

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  6. Patients suffering from cancers are increasingly numerous in general practice consultations. The General Practitioner (GP) should be at the heart of the management of patients. Several studies have examined th...

    Authors: Vladimir Druel, Laetitia Gimenez, Kim Paricaud, Jean-Pierre Delord, Pascale Grosclaude, Nathalie Boussier and Marie-Eve Rougé Bugat

    Citation: BMC Cancer 2020 20:495

    Content type: Research article

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  7. It is well known that women suffer from negative consequences following breast cancer (BC) treatment and that their largely varying needs for rehabilitation are often unmet. Up to 43% of these women are at ris...

    Authors: U. Olsson Möller, L. Rydén and M. Malmström

    Citation: BMC Cancer 2020 20:484

    Content type: Study protocol

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  8. Although cancer-related fatigue (CRF) has gained increased attention in the past decade, therapy remains a challenge. Treatment programs are more likely to be effective if the needs and interests of the person...

    Authors: Claudia Canella, Michael Mikolasek, Matthias Rostock, Matthias Guckenberger, Josef Jenewein, Esther Linka, Claudia Six, Sarah Stoll, Roger Stupp and Claudia M. Witt

    Citation: BMC Cancer 2020 20:458

    Content type: Research article

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  9. Evidence suggests that physical activity (PA) is beneficial for reducing fatigue in colorectal cancer (CRC) survivors. However, little is known regarding long-term effects of PA on fatigue and whether pre-diag...

    Authors: Ruth Elisa Eyl, Melissa S. Y. Thong, Prudence R. Carr, Lina Jansen, Lena Koch-Gallenkamp, Michael Hoffmeister, Jenny Chang-Claude, Hermann Brenner and Volker Arndt

    Citation: BMC Cancer 2020 20:438

    Content type: Research article

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  10. The prevalence and correlates of job and insurance problems were examined among a cohort of young U.S. breast cancer survivors during the first 18-months following diagnosis.

    Authors: Michelle J. Naughton, Chloe M. Beverly Hery, Sarah A. Janse, Elizabeth Z. Naftalis, Electra D. Paskett and Kimberly J. Van Zee

    Citation: BMC Cancer 2020 20:432

    Content type: Research article

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  11. Identification of patient-related factors associated with Health-Related Quality of Life (HRQoL) and Quality of Life (QoL) at the start of treatment may identify patients who are prone to a decrease in HRQoL a...

    Authors: Mark de Mol, Sabine Visser, Joachim Aerts, Paul Lodder, Nico van Walree, Huub Belderbos and Brenda den Oudsten

    Citation: BMC Cancer 2020 20:431

    Content type: Research article

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  12. Our aim was to investigate the value of serum squamous cell carcinoma (SCC) antigen levels in predicting chemosensitivity, lymph node metastasis, as well as prognosis in patients with cervical squamous cell ca...

    Authors: Peng Chen, Liang Jiao, Fang Ren and Dan-Bo Wang

    Citation: BMC Cancer 2020 20:423

    Content type: Research article

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  13. Curative treatment for upper gastrointestinal (UGI) and hepatopancreaticobiliary (HPB) cancers, involves complex surgical resection often in combination with neoadjuvant/adjuvant chemo/chemoradiotherapy. With ...

    Authors: Linda O’Neill, Emer Guinan, Suzanne Doyle, Deirdre Connolly, Jacintha O’Sullivan, Annemarie Bennett, Grainne Sheill, Ricardo Segurado, Peter Knapp, Ciaran Fairman, Charles Normand, Justin Geoghegan, Kevin Conlon, John V. Reynolds and Juliette Hussey

    Citation: BMC Cancer 2020 20:415

    Content type: Study protocol

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  14. Head and Neck cancer (HNC) is characterized by significant mortality and morbidity. Treatment is often invasive and interferes with vital functions, resulting in a delicate balance between survival benefit and...

    Authors: Arta Hoesseini, Emilie A. C. Dronkers, Aniel Sewnaik, Jose A. U. Hardillo, Robert J. Baatenburg de Jong and Marinella P. J. Offerman

    Citation: BMC Cancer 2020 20:399

    Content type: Research article

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  15. Spatial heterogeneity of prostate cancer-specific mortality in Pennsylvania remains unclear. We utilized advanced geospatial survival regressions to examine spatial variation of prostate cancer-specific mortal...

    Authors: Ming Wang, Emily Wasserman, Nathaniel Geyer, Rachel M. Carroll, Shanshan Zhao, Lijun Zhang, Raymond Hohl, Eugene J. Lengerich and Alicia C. McDonald

    Citation: BMC Cancer 2020 20:394

    Content type: Research article

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  16. The ABCSG-28 trial compared primary surgery followed by systemic therapy versus primary systemic therapy without surgery in patients with de novo stage IV BC. The present report describes QoL results of this t...

    Authors: V. Bjelic-Radisic, F. Fitzal, M. Knauer, G. Steger, D. Egle, R. Greil, P. Schrenk, M. Balic, Ch. Singer, R. Exner, L. Soelkner and Michael Gnant

    Citation: BMC Cancer 2020 20:392

    Content type: Research article

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  17. The purpose of this study was to assess the efficacy and safety of cisplatin-based chemotherapy with or without bevacizumab (BEV) in Chinese women with advanced cervical cancer (ACC).

    Authors: Xiaoli He, Jun Liu, Li Xiao, Mingdong Zhao, Tingting Su, Tiejian Liu, Guowei Han and Yue Wang

    Citation: BMC Cancer 2020 20:381

    Content type: Research article

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  18. As more states legalize cannabis for medical and recreational use, people increasingly use cannabis to treat medical conditions and associated symptoms. The prevalence and utility of cannabis for cancer-relate...

    Authors: Susan L. Calcaterra, Andrea N. Burnett-Hartman, J. David Powers, Douglas A. Corley, Carmit M. McMullen, Pamala A. Pawloski and Heather Spencer Feigelson

    Citation: BMC Cancer 2020 20:373

    Content type: Research article

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  19. Self-management is becoming essential for breast cancer survivors, but evidence about the effectiveness of self-management support (SMS) intervention is lacking. To address this issue, we developed a theory-ba...

    Authors: Soo Hyun Kim, Yu Hyeon Choe, Ah Reum Han, Gwui Jeong Yeon, Gyeong Hee Lee, Bo Gyeong Lee, Young Up Cho, Seho Park and Moon Hee Lee

    Citation: BMC Cancer 2020 20:367

    Content type: Study protocol

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  20. Women with ductal carcinoma in situ (DCIS) report poor patient-clinician communication, and long-lasting confusion and anxiety about their treatment and prognosis. Research shows that patient-centred care (PCC...

    Authors: Bryanna B. Nyhof, Frances C. Wright, Nicole J. Look Hong, Gary Groot, Lucy Helyer, Pamela Meiers, May Lynn Quan, Nancy N. Baxter, Robin Urquhart, Rebecca Warburton and Anna R. Gagliardi

    Citation: BMC Cancer 2020 20:364

    Content type: Research article

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  21. Dysphagia or difficulty in swallowing affects quality of life for most patients with head and neck cancer. SIP SMART – [Swallowing Intervention Package: Self-Monitoring, Assessment, Rehabilitation Training] ai...

    Authors: Roganie Govender, Christina H. Smith, Helen Barratt, Benjamin Gardner and Stuart A. Taylor

    Citation: BMC Cancer 2020 20:360

    Content type: Research article

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  22. The number of people living with soft-tissue and bone sarcomas is increasing due to improved individual therapy and changes in demographics. At present, there are no recommendations for psychological co-treatm...

    Authors: Wolfram Weschenfelder, Sabine Gast-Froehlich, Christian Spiegel, Matthias Vogt and Gunther O. Hofmann

    Citation: BMC Cancer 2020 20:351

    Content type: Research article

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  23. Patients with cancer of the lung or oesophagus, undergoing curative treatment, usually require a thoracotomy and a complex oncological resection. These surgeries carry a risk of major morbidity and mortality, ...

    Authors: Gráinne Sheill, Emer Guinan, Linda O’Neill, Charles Normand, Suzanne L. Doyle, Sarah Moore, John Newell, Grainne McDermott, Ronan Ryan, John V. Reynolds and Juliette Hussey

    Citation: BMC Cancer 2020 20:321

    Content type: Study protocol

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  24. Cancer development is mediated by oxidative stress and inflammation, which may correlate with metabolic disorders. The aim of this study was to evaluate antioxidant vitamins status and metabolic parameters in ...

    Authors: Man-Yee Chan, Bor-Jen Lee, Po-Sheng Chang, Han-Yu Hsiao, Li-Ping Hsu, Chia-Hua Chang and Ping-Ting Lin

    Citation: BMC Cancer 2020 20:310

    Content type: Research article

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  25. Gastrointestinal tract function and it’s integrity are controlled by a number of peptides whose secretion is influenced by severe inflammation. In stomach the main regulatory peptide is ghrelin. For upper smal...

    Authors: Szymon Skoczeń, Magdalena Rej, Kinga Kwiecińska, Danuta Pietrys, Przemysław J. Tomasik, Małgorzata Wójcik, Wojciech Strojny, Agnieszka Dłużniewska, Katarzyna Klimasz, Kamil Fijorek, Michał Korostyński, Marcin Piechota and Walentyna Balwierz

    Citation: BMC Cancer 2020 20:306

    Content type: Research article

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  26. Cancer immunotherapy via immune-checkpoint inhibition (ICI) by antibodies against cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and cell death protein 1 (PD-1) have significantly improved the outcome of...

    Authors: J. Boegeholz, C. S. Brueggen, C. Pauli, F. Dimitriou, E. Haralambieva, R. Dummer, M. G. Manz and C. C. Widmer

    Citation: BMC Cancer 2020 20:300

    Content type: Research article

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  27. Cancer survivors and their caregivers may have various unmet needs that are medically difficult to solve. Previous studies have suggested the relations between individuals’ backgrounds and their unmet needs. W...

    Authors: Kaname Watanabe, Kayoko Katayama, Takashi Yoshioka and Hiroto Narimatsu

    Citation: BMC Cancer 2020 20:263

    Content type: Research article

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  28. In high-income countries (HICs), increased rates of survival among pediatric cancer patients are achieved through the use of protocol-driven treatment. Compared to HICs, differences in infrastructure, supporti...

    Authors: Lavanya Vasudevan, Kristin Schroeder, Yadurshini Raveendran, Kunal Goel, Christina Makarushka, Nestory Masalu and Leah L. Zullig

    Citation: BMC Cancer 2020 20:254

    Content type: Study protocol

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  29. Patients with multiple myeloma report more problems with quality of life (QoL) than other haematological malignancies over the course of their incurable illness. The patient-centred Myeloma Patient Outcome Sca...

    Authors: Christina Gerlach, Katherine Taylor, Marion Ferner, Markus Munder, Martin Weber and Christina Ramsenthaler

    Citation: BMC Cancer 2020 20:245

    Content type: Research article

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  30. NEPA is an oral fixed-dose combination of netupitant, a new highly selective neurokinin-1 receptor antagonist, and palonosetron. This study was conducted to evaluate whether the efficacy of NEPA against chemot...

    Authors: Roberta Caputo, Marina Elena Cazzaniga, Andrea Sbrana, Rosalba Torrisi, Ida Paris, Monica Giordano, Vincenzo Montesarchio, Valentina Guarneri, Laura Amaducci, Domenico Bilancia, Giuseppina Cilenti, Alessandra Fabi, Elena Collovà, Alessio Schirone, Erminio Bonizzoni, Luigi Celio…

    Citation: BMC Cancer 2020 20:232

    Content type: Research article

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  31. Cognitive therapy has been shown to reduce fear of cancer recurrence (FCR), mainly in breast cancer survivors. The accessibility of cognitive behavioural interventions could be further improved by Internet del...

    Authors: Johanne Dam Lyhne, Allan ‘ Ben’ Smith, Lisbeth Frostholm, Per Fink and Lars Henrik Jensen

    Citation: BMC Cancer 2020 20:223

    Content type: Study protocol

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  32. To analyze the effects of BRCA1/2 mutations on chemotherapy response scores (CRS) and survival in a cohort of patients with advanced-stage ovarian cancer who were treated with neoadjuvant chemotherapy (NAC) follo...

    Authors: Yong Jae Lee, Hyun-Soo Kim, John Hoon Rim, Jung-Yun Lee, Eun Ji Nam, Sang Wun Kim, Sunghoon Kim and Young Tae Kim

    Citation: BMC Cancer 2020 20:185

    Content type: Research article

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  33. Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer death in women worldwide. Recently, studies have been published with inconsistent findings regarding whether sarcopenia is a ...

    Authors: Xiao-Ming Zhang, Qing-Li Dou, Yingchun Zeng, Yunzhi Yang, Andy S. K. Cheng and Wen-Wu Zhang

    Citation: BMC Cancer 2020 20:172

    Content type: Research article

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  34. Bone complications (pathologic fracture, spinal cord compression, surgery to bone and radiation to bone) are a common problem in patients with multiple myeloma (MM). We set out to provide insights into the rea...

    Authors: María-Victoria Mateos, Leah Fink, Niranchana Koneswaran, Michele Intorcia, Christina Giannopoulou, Daniela Niepel and Michele Cavo

    Citation: BMC Cancer 2020 20:170

    Content type: Research article

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  35. Multiple myeloma is a cancer in the bone marrow causing bone destruction. Patients experience various symptoms related to the disease and/or treatment, such as pain and fatigue, leading to poorer quality of li...

    Authors: Rikke Faebo Larsen, Mary Jarden, Lisbeth Rosenbek Minet, Ulf Christian Frølund, Sören Möller and Niels Abildgaard

    Citation: BMC Cancer 2020 20:169

    Content type: Research article

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  36. Overweight/obesity are strongly implicated in breast cancer development, and weight gain post-diagnosis is associated with greater morbidity and all-cause mortality. The aim of this study was to describe the p...

    Authors: Carolyn Ee, Adele Elizabeth Cave, Dhevaksha Naidoo, Kellie Bilinski and John Boyages

    Citation: BMC Cancer 2020 20:113

    Content type: Research article

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  37. Colorectal cancer (CRC) in patients aged under 55 years is on the rise, constituting approximately 10% of cases. Our aim was to determine the survival and clinico-pathological details of young-onset CRC (yCRC)...

    Authors: Sarah Perrott, Kirsten Laurie, Kirsten Laws, Annie Johnes, Zosia Miedzybrodzka and Leslie Samuel

    Citation: BMC Cancer 2020 20:108

    Content type: Research article

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  38. Gliomas consist of a heterogeneous group of tumors. This study aimed to report the incidences of O6-methylguanine-DNA-methyltransferase (MGMT) promoter methylation, 1p19q co-deletion, isocitrate dehydrogenase (ID...

    Authors: Samantha Ya Lyn Ang, Lester Lee, Angela An Qi See, Ting Yao Ang, Beng Ti Ang and Nicolas Kon Kam King

    Citation: BMC Cancer 2020 20:79

    Content type: Research article

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  39. This study aimed to compare clinical outcomes following placement of fully covered self-expanding metallic stents (FCSEMS) vs partially covered self-expanding metallic stents (PCSEMS) for palliative treatment ...

    Authors: Chunmei Wang, Hua Wei and Yuxia Li

    Citation: BMC Cancer 2020 20:73

    Content type: Research article

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  40. Kaposi’s sarcoma (KS) is one of the most common HIV-associated malignancies in sub-Saharan Africa. Worldwide, the availability of antiretroviral therapy (ART) has improved KS survival. In resource-rich setting...

    Authors: Esther E. Freeman, Naftali Busakhala, Susan Regan, Fredrick Chite Asirwa, Megan Wenger, Divya Seth, Khatiya Chelidze Moon, Aggrey Semeere, Toby Maurer, Kara Wools-Kaloustian, Ingrid Bassett and Jeffrey Martin

    Citation: BMC Cancer 2020 20:71

    Content type: Research article

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  41. The precise content and frequency of follow-up of patients with colorectal cancer (CRC) is variable and guideline adherence is low. The aim of this study was to assess the view of colorectal surgeons on their ...

    Authors: S. M. Qaderi, N. A. T. Wijffels, A. J. A. Bremers and J. H. W. de Wilt

    Citation: BMC Cancer 2020 20:22

    Content type: Research article

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  42. Improved, multimodal treatment strategies have been shown to increase cure rates in cancer patients. Those who survive cancer as a child, adolescent or young adult (CAYA), are at a higher risk for therapy-, or...

    Authors: J. Salchow, J. Mann, B. Koch, J. von Grundherr, W. Jensen, S. Elmers, L. A. Straub, E. Vettorazzi, G. Escherich, S. Rutkowski, S. Dwinger, C. Bergelt, M. Sokalska-Duhme, S. Bielack, G. Calaminus, K. Baust…

    Citation: BMC Cancer 2020 20:16

    Content type: Study protocol

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  43. There is absence of literature related to cough prevalence and its characteristics in lung cancer patients, with information deriving only from broader symptoms occurrence studies. The aims of this study were ...

    Authors: Amélie Harle, Alex Molassiotis, Oliver Buffin, Jack Burnham, Jaclyn Smith, Janelle Yorke and Fiona H. Blackhall

    Citation: BMC Cancer 2020 20:9

    Content type: Research article

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  44. Nausea can be particularly prominent during the delayed period. Therefore, we performed a meta-analysis of the available randomised evidence to assess the average effect of palonosetron plus one-day dexamethas...

    Authors: Luigi Celio, Erminio Bonizzoni, Emma Zattarin, Paolo Codega, Filippo de Braud and Matti Aapro

    Citation: BMC Cancer 2019 19:1268

    Content type: Research article

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  45. Previous studies have indicated that accompanying socially underserved cancer patients through Patient Navigator (PN) or PN-derived procedures improves therapy management and reassurance. At the Cancer Institu...

    Authors: K. G. Koffi, D. A. Silué, C. Laurent, K. Boidy, S. Koui, G. Compaci, Z. H. Adeba, I. Kamara, R. P. Botty, A. S. Bognini, I. Sanogo, F. Despas and G. Laurent

    Citation: BMC Cancer 2019 19:1247

    Content type: Research article

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  46. The gut microbiota is an important modulator of immune, metabolic, psychological and cognitive mechanisms. Chemotherapy adversely affects the gut microbiota, inducing acute dysbiosis, and alters physiological ...

    Authors: Julie M. Deleemans, Faye Chleilat, Raylene A. Reimer, Jan-Willem Henning, Mohamad Baydoun, Katherine-Ann Piedalue, Andrew McLennan and Linda E. Carlson

    Citation: BMC Cancer 2019 19:1243

    Content type: Study protocol

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  47. Cervical cancer is a cancer of uterine cervix caused mostly by sexually-acquired infection called Human papillomavirus (HPV. In developing region of the globe, fewer than 50% of women with cervical malignancy ...

    Authors: Mulugeta Wassie, Zeleke Argaw, Yosief Tsige, Mesfin Abebe and Sezer Kisa

    Citation: BMC Cancer 2019 19:1221

    Content type: Research article

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  48. Granulocyte-colony stimulating factor (G-CSF) is increasingly been used to prevent febrile neutropenia (FN) associated with the administration of chemotherapy for various cancers. The most common adverse effec...

    Authors: Hideko Hoshina and Hiroyuki Takei

    Citation: BMC Cancer 2019 19:1217

    Content type: Case report

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  49. On the basis of some significant clinical parameters, we had an intent to establish nomograms for estimating the prognosis of patients with squamous cell carcinoma of the urinary bladder (SCCB), including over...

    Authors: Guanghao Zhang, Zhiwei Li, Daoqing Song and Zhiqing Fang

    Citation: BMC Cancer 2019 19:1200

    Content type: Research article

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  50. Hormone replacement therapy (HRT) use has shown to be associated with a reduced risk of colorectal cancer, however, its impact on survival among women with colorectal cancer remains uncertain. This meta-analys...

    Authors: Yeu-Chai Jang, Hsi-Lan Huang and Chi Yan Leung

    Citation: BMC Cancer 2019 19:1199

    Content type: Research article

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