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Survivorship

This section focuses on research related to post-treatment cancer survivors. Topics of interest include, but are not limited to, long-term studies on adverse events/side effects of cancer treatment, mortality of young cancer survivors, policy-related research that can impact the quality of care and quality of life of cancer survivors, recent guidelines for investigation of complications after treatment in child and adult cancers.

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  1. Both breast-conserving surgery and breast reconstruction surgery are less popular in China, although they can improve patients’ quality of life. The main reason comes from the economy. There is currently no ec...

    Authors: Qing Yang, Xiaorong Zhong, Wei Zhang, Ting Luo, Ping He and Hong Zheng

    Citation: BMC Cancer 2021 21:107

    Content type: Research article

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  2. Treatment of head and neck cancer (HNC) often leads to visible and severe functional impairments. In addition, patients often suffer from a variety of psychosocial problems, significantly associated with a dec...

    Authors: C. Hammermüller, A. Hinz, A. Dietz, G. Wichmann, M. Pirlich, T. Berger, K. Zimmermann, T. Neumuth, A. Mehnert-Theuerkauf, S. Wiegand and V. Zebralla

    Citation: BMC Cancer 2021 21:94

    Content type: Research article

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  3. The successful transition of childhood cancer survivors (CCSs) from pediatric to adult long-term follow-up care is a critical phase, and determining the right time point can be challenging. We assessed the fea...

    Authors: Maria Otth, Patrick Wechsler, Sibylle Denzler, Henrik Koehler and Katrin Scheinemann

    Citation: BMC Cancer 2021 21:84

    Content type: Research article

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  4. A serious syndrome for cancer in-patients, delirium risk increases with age and medical acuity. Screening tools exist but detection is frequently delayed or missed. We test the ‘Single Question in Delirium’ (S...

    Authors: Megan B. Sands, Swapnil Sharma, Lindsay Carpenter, Andrew Hartshorn, Jessica T. Lee, Sanja Lujic, Megan E. Congdon, Angus M. Buchanan, Meera Agar and Janette L. Vardy

    Citation: BMC Cancer 2021 21:75

    Content type: Research article

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  5. Patients with lung cancer who are treated with carboplatin-based chemotherapy regimens often experience chemotherapy-induced nausea and vomiting (CINV). However, knowledge on the effect of regimen and cofactor...

    Authors: Toshinobu Hayashi, Mototsugu Shimokawa, Koichi Matsuo, Hirotoshi Iihara, Kei Kawada, Takafumi Nakano and Takashi Egawa

    Citation: BMC Cancer 2021 21:74

    Content type: Research article

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  6. Surgical resection remains the only curative treatment for pancreatic cancer and is associated with significant post-operative morbidity and mortality. Patients eligible for surgery, increasingly receive neo-a...

    Authors: Dominic O’Connor, Malcolm Brown, Martin Eatock, Richard C. Turkington and Gillian Prue

    Citation: BMC Cancer 2021 21:43

    Content type: Research article

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  7. An upgraded understanding of factors (sex/estrogen) associated with survival benefit in advanced colorectal carcinoma (CRC) could improve personalised management and provide innovative insights into anti-tumou...

    Authors: Chunlong Huang, Xiaoyuan Gu, Xianshang Zeng, Baomin Chen, Weiguang Yu and Meiji Chen

    Citation: BMC Cancer 2021 21:30

    Content type: Research article

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  8. Kidney cancer (KC) is associated with cardiovascular regulation disorder and easily leads to cardiovascular and cerebrovascular death (CCD), which is one of the major causes of death in patients with KC, espec...

    Authors: Xiaofei Mo, Mingge Zhou, Hui Yan, Xueqin Chen and Yuetao Wang

    Citation: BMC Cancer 2021 21:13

    Content type: Research article

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  9. At intensive care unit (ICU) admission, the issue about prognosis of critically ill cancer patients is of clinical interest, especially after ICU discharge. Our objective was to assess the factors associated w...

    Authors: Hubert Gheerbrant, Jean-François Timsit, Nicolas Terzi, Stéphane Ruckly, Mathieu Laramas, Matteo Giaj Levra, Emmanuelle Jacquet, Loic Falque, Denis Moro-Sibilot and Anne-Claire Toffart

    Citation: BMC Cancer 2021 21:9

    Content type: Research article

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  10. Immune checkpoint inhibitors and targeted therapies are approved for adjuvant treatment of patients with resected melanoma; however, they have not been compared in randomized controlled trials (RCTs). We compa...

    Authors: Kabirraaj Toor, Mark R. Middleton, Keith Chan, Adenike Amadi, Andriy Moshyk and Srividya Kotapati

    Citation: BMC Cancer 2021 21:3

    Content type: Research article

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  11. This study examined current physical activity levels and preferences for exercise settings and activities among adult survivors of childhood cancers as a strategy to inform the feasibility and design of such p...

    Authors: Denise Rokitka, Jennifer Heffler, Michael Zevon, Caleb Kitcho, Jennifer Schweitzer, Elisa M. Rodriguez and Martin C. Mahoney

    Citation: BMC Cancer 2021 21:1

    Content type: Research article

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  12. Little is known about treatment expectations of patients with spinal metastases undergoing radiotherapy and/or surgery. Assuming that patients with spinal metastases share characteristics with patients who had...

    Authors: R. Gal, D. Oostinga, H. Wessels, J. J. Verlaan, R. Charest-Morin, C. G. Fisher, H. M. Verkooijen and A. L. Versteeg

    Citation: BMC Cancer 2020 20:1212

    Content type: Research article

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  13. Surgical resection is the major way to cure pancreatic ductal adenocarcinoma (PDAC). However, this operation is complex, and the peri-operative risk is high, making patients more likely to be admitted to the i...

    Authors: Yijue Zhang, Sibo Zhu, Zhiqing Yuan, Qiwei Li, Ruifeng Ding, Xunxia Bao, Timing Zhen, Zhiliang Fu, Hailong Fu, Kaichen Xing, Hongbin Yuan and Tao Chen

    Citation: BMC Cancer 2020 20:1161

    Content type: Research article

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  14. The aim of this study was to translate and linguistically validate the U.S. National Cancer Institute’s Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE™) into...

    Authors: Cheng KKF, S. A. Mitchell, N. Chan, E. Ang, W. Tam and R. Kanesvaran

    Citation: BMC Cancer 2020 20:1153

    Content type: Research article

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  15. Population-based analysis for the short-term non-bladder cancer related mortality among patients with non-metastatic bladder cancer is currently lacking. The objective of the current study was to assess and qu...

    Authors: Menghe Zhai, Chenye Tang, Ming Li, Xin Chen, Yigang Jin, Xiangjun Ying, Zhiling Tang, Xiao Wang, Yuntao Wu, Chun Sun, Kean Chen and Xiao Guo

    Citation: BMC Cancer 2020 20:1148

    Content type: Research article

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  16. Breast cancer is the most common malignancy in women, and it is also the leading cause of death in female patients; the most common pathological type of BC is infiltrating duct carcinoma (IDC). Some nomograms ...

    Authors: Zhangheng Huang, Chuan Hu, Kewen Liu, Luolin Yuan, Yinglun Li, Chengliang Zhao and Chanchan Hu

    Citation: BMC Cancer 2020 20:1145

    Content type: Research article

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  17. Prehabilitation with regular exercise and nutritional care for patients undergoing surgeries for malignant disease was recently introduced to increase physiologic reserve prior to the procedure, accelerate rec...

    Authors: Erik Rupnik, Matevz Skerget, Matjaz Sever, Irena Preloznik Zupan, Maja Ogrinec, Barbara Ursic, Natasa Kos, Peter Cernelc and Samo Zver

    Citation: BMC Cancer 2020 20:1142

    Content type: Research article

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  18. Little is known about the presentation, help seeking behaviour for breast cancer in Singapore. Nor was there a study exploring the experience of patients in their breast cancer journey.

    Authors: Celene W. Q. Ng, Jennifer N. W. Lim, Jenny Liu and Mikael Hartman

    Citation: BMC Cancer 2020 20:1080

    Content type: Research article

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  19. This analysis aims to evaluate health-related quality of life (HrQoL) (primary outcome for this analysis), nausea and vomiting, and pain in patients with inoperable malignant bowel obstruction (IMBO) due to ca...

    Authors: Nikki McCaffrey, Tegan Asser, Belinda Fazekas, Wendy Muircroft, Meera Agar, Katherine Clark, Simon Eckermann, Jessica Lee, Rohit Joshi, Peter Allcroft, Caitlin Sheehan and David C. Currow

    Citation: BMC Cancer 2020 20:1050

    Content type: Research article

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  20. Dynapenia is defined as an age-related loss of muscle strength. There is little information on dynapenia in cancer patients and on how it relates to anthropometric variables. The aim of this study was to analy...

    Authors: Ana Beatriz Rechinelli, Isabele Lessa Marques, Eduarda Cristina Rodrigues de Morais Viana, Isadora da Silva Oliveira, Vanusa Felício de Souza, Glenda Blaser Petarli, Jose Luiz Marques Rocha and Valdete Regina Guandalini

    Citation: BMC Cancer 2020 20:1010

    Content type: Research article

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  21. Baseline cardiovascular disease (CVD) can impact the patterns of treatment and hence the outcomes of patients with lung cancer. This study aimed to characterize treatment trends and survival outcomes of patien...

    Authors: Atul Batra, Dropen Sheka, Shiying Kong and Winson Y. Cheung

    Citation: BMC Cancer 2020 20:1004

    Content type: Research article

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  22. Increasing evidence indicates that the pathology and the modified Kadish system have some influence on the prognosis of esthesioneuroblastoma (ENB). However, an accurate system to combine pathology with a modi...

    Authors: Lijie Jiang, Tengjiao Lin, Yu Zhang, Wenxiang Gao, Jie Deng, Zhaofeng Xu, Xin Luo, Zhaoqi Huang, Fenghong Chen, Jianbo Shi and Yinyan Lai

    Citation: BMC Cancer 2020 20:993

    Content type: Research article

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  23. Currently, oral targeted therapies are known to be effective and are frequently used to treat metastatic cancer patients, but fatigue is a frequently reported early side effect of these treatments. This fatigu...

    Authors: Florence Joly, Claudia Lefeuvre-Plesse, Claire Garnier-Tixidre, Carole Helissey, Nathalie Menneveau, Alain Zannetti, Sebastien Salas, Nadine Houede, Sophie Abadie-Lacourtoisie, Laetitia Stefani, Soazig Nenan, Isabelle Rieger, Isabelle Durand-Zaleski, Jean-Marc Descotes and Amélie Anota

    Citation: BMC Cancer 2020 20:975

    Content type: Study protocol

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  24. Optimal management strategies for clinically localised prostate cancer are debated. Using median 10-year data from the largest randomised controlled trial to date (ProtecT), the lifetime cost-effectiveness of ...

    Authors: S. Sanghera, S. Mohiuddin, J. Coast, K. Garfield, S. Noble, C. Metcalfe, J. A. Lane, E. L. Turner, D. Neal, F. C. Hamdy, R. M. Martin and J. L. Donovan

    Citation: BMC Cancer 2020 20:971

    Content type: Research article

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  25. Healthy Living after Cancer (HLaC) was a national dissemination and implementation study of an evidence-based lifestyle intervention for cancer survivors. The program was imbedded into existing telephone cance...

    Authors: Elizabeth G. Eakin, Marina M. Reeves, Ana D. Goode, Elisabeth A. H. Winkler, Janette L. Vardy, Frances Boyle, Marion R. Haas, Janet E. Hiller, Gita D. Mishra, Michael Jefford, Bogda Koczwara, Christobel M. Saunders, Kathy Chapman, Liz Hing, Anna G. Boltong, Katherine Lane…

    Citation: BMC Cancer 2020 20:963

    Content type: Research article

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  26. Breast cancer care today involves state-of-the-art biomedical treatment but can fail to address the broader psychosocial and quality-of-life (QoL) issues associated with the transition to breast cancer survivo...

    Authors: Michael G. Culbertson, Kathleen Bennett, Catherine M. Kelly, Linda Sharp and Caitriona Cahir

    Citation: BMC Cancer 2020 20:948

    Content type: Research article

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  27. Supportive care Prioritization, Assessment and Recommendations for Kids (SPARK) is a web-based application that facilitates symptom screening and access to supportive care clinical practice guidelines (CPGs) f...

    Authors: Cody Z. Watling, Clodagh McCarthy, Alexandra Theodorakidis, Sadie Cook, Emily Vettese, Tal Schechter, Hanan Abubeker, L. Lee Dupuis and Lillian Sung

    Citation: BMC Cancer 2020 20:923

    Content type: Research article

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  28. Results from a phase III, randomized, double-blind, active comparator-controlled, parallel-group trial evaluating fosaprepitant for the prevention of chemotherapy-induced nausea and vomiting (CINV) found that ...

    Authors: Cindy Weinstein, Karin Jordan, Stuart Green, Saleem Khanani, Elizabeth Beckford-Brathwaite, Waldimir Vallejos, Annpey Pong, Stephen J. Noga and Bernardo L. Rapoport

    Citation: BMC Cancer 2020 20:918

    Content type: Research article

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  29. The study aimed to investigate the clinical features and prognosis factors of adult patients with Langerhans cell histiocytosis (LCH) with pulmonary involvement, especially multisystem (MS) LCH with pulmonary ...

    Authors: Hui-lei Miao, Ai-lin Zhao, Ming-hui Duan, Dao-bin Zhou, Xin-xin Cao and Jian Li

    Citation: BMC Cancer 2020 20:911

    Content type: Research article

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  30. Art therapy may improve the physical, mental, and emotional wellbeing of individuals for a variety of purposes. It remains understudied and underutilized in cancer care. We sought to determine the ability of a...

    Authors: E. B. Elimimian, L. Elson, E. Stone, R. S. Butler, M. Doll, S. Roshon, C. Kondaki, A. Padgett and Z. A. Nahleh

    Citation: BMC Cancer 2020 20:899

    Content type: Research article

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    The Correction to this article has been published in BMC Cancer 2020 20:1125

  31. Adolescent and young adult (AYA) childhood cancer survivors (CCS) should be empowered to continue their survivor-focused care as they transition into adult medicine. However, the majority of AYA-aged survivors...

    Authors: Karim Thomas Sadak, Milki T. Gemeda, Michelle Grafelman, Joseph P. Neglia, David R. Freyer, Eileen Harwood and Jude Mikal

    Citation: BMC Cancer 2020 20:898

    Content type: Research article

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  32. Cytotoxic chemotherapy can cure advanced germ cell tumors. Nevertheless, cancer treatment may induce cellular senescence and accelerate molecular aging. The aging process implies an increase of cells expressing p...

    Authors: Maria T. Bourlon, Hugo E. Velazquez, Juan Hinojosa, Luis Orozco, Ricardo Rios-Corzo, Guadalupe Lima, Luis Llorente, Diego F. Hernandez-Ramirez, Francisco J. Valentin-Cortez, Irene Medina-Rangel and Yemil Atisha-Fregoso

    Citation: BMC Cancer 2020 20:882

    Content type: Research article

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  33. Terminal-stage solid tumors are one of the main causes of disseminated intravascular coagulation (DIC); effective therapeutic strategies are therefore warranted. This study aimed to investigate the association...

    Authors: Kohei Taniguchi, Hiroyuki Ohbe, Kazuma Yamakawa, Hiroki Matsui, Kiyohide Fushimi and Hideo Yasunaga

    Citation: BMC Cancer 2020 20:867

    Content type: Research article

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  34. Endocrine therapy (ET)-based regimens are the mainstay of treatment for patients with hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2−) advanced breast cancer. With the in...

    Authors: Alison Davie, Gebra Cuyun Carter, Alex Rider, James Pike, Katie Lewis, Abigail Bailey, Gregory L. Price, Francois Ringeisen and Xavier Pivot

    Citation: BMC Cancer 2020 20:855

    Content type: Research article

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  35. As inadequate pain communication contributes to difficulties in optimizing outcomes of outpatients, we investigated the effect of reinforced education using WeChat App to the opioid titration treatment of canc...

    Authors: Zhiyou Peng, Lin Li, Yuan Chen, Zhiying Feng and Xiangming Fang

    Citation: BMC Cancer 2020 20:852

    Content type: Research article

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  36. Both the 7th and 8th editions of the American Joint Committee on Cancer (AJCC) staging system for perihilar cholangiocarcinoma (pCCA) had the same definition for T2a and T2b. But the value of this classificati...

    Authors: Jian Zhao, Wei Zhang, Jun Zhang, Yi Zhang, Wen-Jie Ma, Si-Yun Liu, Fu-Yu Li and Bin Song

    Citation: BMC Cancer 2020 20:849

    Content type: Research article

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  37. Screening for early detection of lung cancer has been performed in high-risk individuals with smoking history. However, researches on the distribution, clinical characteristics, and prognosis of these high-ris...

    Authors: Woo Ho Ban, Chang Dong Yeo, Solji Han, Hye Seon Kang, Chan Kwon Park, Ju Sang Kim, Jin Woo Kim, Seung Joon Kim, Sang Haak Lee and Sung Kyoung Kim

    Citation: BMC Cancer 2020 20:848

    Content type: Research article

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  38. Cervical cancer has long been a common malignance troubling women. However, there are few studies developing nomogram with comprehensive factors for the prognosis of cervical cancer. Hence, we aimed to build a...

    Authors: Guilan Xie, Ruiqi Wang, Li Shang, Cuifang Qi, Liren Yang, Liyan Huang, Wenfang Yang and Mei Chun Chung

    Citation: BMC Cancer 2020 20:833

    Content type: Research article

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  39. Tyrosine-kinase inhibitors (TKIs) have become the cornerstone treatment of patients with non-small cell lung cancer that harbor oncogenic EGFR mutations. The counterpart of these drugs is the financial burden ...

    Authors: Oscar Arrieta, Rodrigo Catalán, Silvia Guzmán-Vazquez, Feliciano Barrón, Luis Lara-Mejía, Herman Soto-Molina, Maritza Ramos-Ramírez, Diana Flores-Estrada and Jaime de la Garza

    Citation: BMC Cancer 2020 20:829

    Content type: Research article

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  40. The empirical dietary index for hyperinsulinemia (EDIH) score is a validated food-based dietary score that assesses the ability of whole-food diets to predict plasma c-peptide concentrations. Although the EDIH...

    Authors: Fred K. Tabung, Anne Noonan, Dong Hoon Lee, Mingyang Song, Steven K. Clinton, Daniel Spakowicz, Kana Wu, En Cheng, Jeffrey A. Meyerhardt, Charles S. Fuchs and Edward L. Giovannucci

    Citation: BMC Cancer 2020 20:817

    Content type: Research article

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  41. Pulmonary blastoma (PB) is a rare lung primary malignancy with poorly understood risk factors and prognosis. We sought to investigate the epidemiologic features and long-term outcomes of PB.

    Authors: Xiang Bu, Jing Liu, Linyan Wei, Xiqiang Wang and Mingwei Chen

    Citation: BMC Cancer 2020 20:811

    Content type: Research article

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  42. Patients who have undergone radical cystectomy for urinary bladder cancer are not sufficiently physically active and therefore may suffer complications leading to readmissions. A physical rehabilitation progra...

    Authors: Andrea Porserud, Patrik Karlsson, Elisabeth Rydwik, Markus Aly, Lars Henningsohn, Malin Nygren-Bonnier and Maria Hagströmer

    Citation: BMC Cancer 2020 20:805

    Content type: Study protocol

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  43. The five-year cumulative incidence rate in patients diagnosed with stage I small-cell lung cancer (SCLC) who were instructed to undergo surgery was from 40 to 60%.The death competition influence the accuracy o...

    Authors: Jianjie Li, Qiwen Zheng, Xinghui Zhao, Jun Zhao, Tongtong An, Meina Wu, Yuyan Wang, Minglei Zhuo, Jia Zhong, Xue Yang, Bo Jia, Hanxiao Chen, Zhi Dong, Jingjing Wang, Yujia Chi, Xiaoyu Zhai…

    Citation: BMC Cancer 2020 20:793

    Content type: Research article

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  44. Cardiovascular disease (CVD) remains the largest cause of death in breast cancer survivors. The aim of this study was to explore the impact of exercise intensity on aerobic fitness and autonomic cardiac regula...

    Authors: Kellie Toohey, Kate Pumpa, Andrew McKune, Julie Cooke, Marijke Welvaert, Joseph Northey, Clare Quinlan and Stuart Semple

    Citation: BMC Cancer 2020 20:787

    Content type: Research article

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  45. Survivors of germ-cell tumors (GCT) may suffer from long-term adverse consequences. Our study was conducted to assess a long-term sexual functioning in GCT survivors.

    Authors: M. Chovanec, L. Vasilkova, L. Petrikova, J. Obertova, P. Palacka, K. Rejlekova, Z. Sycova-Mila, K. Kalavska, D. Svetlovska, B. Mladosievicova, J. Mardiak and M. Mego

    Citation: BMC Cancer 2020 20:779

    Content type: Research article

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  46. The impact and consequences of cancer on the patients and their family caregivers (FCs) are closely intertwined. Caregivers’ burdens can be increased due to the patients’ unmet needs and unresolved problems. A...

    Authors: Gek Phin Chua, Grace Su Yin Pang, Alethlea Chung Pheng Yee, Patricia Soek Hui Neo, Siqin Zhou, Cindy Lim, Yin Yee Wong, Debra Limin Qu, Fang Ting Pan and Grace Meijuan Yang

    Citation: BMC Cancer 2020 20:768

    Content type: Research article

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