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Survivorship, cancer burden and supportive therapy

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  1. Cancer survivors and their caregivers may have various unmet needs that are medically difficult to solve. Previous studies have suggested the relations between individuals’ backgrounds and their unmet needs. W...

    Authors: Kaname Watanabe, Kayoko Katayama, Takashi Yoshioka and Hiroto Narimatsu

    Citation: BMC Cancer 2020 20:263

    Content type: Research article

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  2. In high-income countries (HICs), increased rates of survival among pediatric cancer patients are achieved through the use of protocol-driven treatment. Compared to HICs, differences in infrastructure, supporti...

    Authors: Lavanya Vasudevan, Kristin Schroeder, Yadurshini Raveendran, Kunal Goel, Christina Makarushka, Nestory Masalu and Leah L. Zullig

    Citation: BMC Cancer 2020 20:254

    Content type: Study protocol

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  3. Patients with multiple myeloma report more problems with quality of life (QoL) than other haematological malignancies over the course of their incurable illness. The patient-centred Myeloma Patient Outcome Sca...

    Authors: Christina Gerlach, Katherine Taylor, Marion Ferner, Markus Munder, Martin Weber and Christina Ramsenthaler

    Citation: BMC Cancer 2020 20:245

    Content type: Research article

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  4. NEPA is an oral fixed-dose combination of netupitant, a new highly selective neurokinin-1 receptor antagonist, and palonosetron. This study was conducted to evaluate whether the efficacy of NEPA against chemot...

    Authors: Roberta Caputo, Marina Elena Cazzaniga, Andrea Sbrana, Rosalba Torrisi, Ida Paris, Monica Giordano, Vincenzo Montesarchio, Valentina Guarneri, Laura Amaducci, Domenico Bilancia, Giuseppina Cilenti, Alessandra Fabi, Elena Collovà, Alessio Schirone, Erminio Bonizzoni, Luigi Celio…

    Citation: BMC Cancer 2020 20:232

    Content type: Research article

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  5. Cognitive therapy has been shown to reduce fear of cancer recurrence (FCR), mainly in breast cancer survivors. The accessibility of cognitive behavioural interventions could be further improved by Internet del...

    Authors: Johanne Dam Lyhne, Allan ‘ Ben’ Smith, Lisbeth Frostholm, Per Fink and Lars Henrik Jensen

    Citation: BMC Cancer 2020 20:223

    Content type: Study protocol

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  6. To analyze the effects of BRCA1/2 mutations on chemotherapy response scores (CRS) and survival in a cohort of patients with advanced-stage ovarian cancer who were treated with neoadjuvant chemotherapy (NAC) follo...

    Authors: Yong Jae Lee, Hyun-Soo Kim, John Hoon Rim, Jung-Yun Lee, Eun Ji Nam, Sang Wun Kim, Sunghoon Kim and Young Tae Kim

    Citation: BMC Cancer 2020 20:185

    Content type: Research article

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  7. Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer death in women worldwide. Recently, studies have been published with inconsistent findings regarding whether sarcopenia is a ...

    Authors: Xiao-Ming Zhang, Qing-Li Dou, Yingchun Zeng, Yunzhi Yang, Andy S. K. Cheng and Wen-Wu Zhang

    Citation: BMC Cancer 2020 20:172

    Content type: Research article

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  8. Bone complications (pathologic fracture, spinal cord compression, surgery to bone and radiation to bone) are a common problem in patients with multiple myeloma (MM). We set out to provide insights into the rea...

    Authors: María-Victoria Mateos, Leah Fink, Niranchana Koneswaran, Michele Intorcia, Christina Giannopoulou, Daniela Niepel and Michele Cavo

    Citation: BMC Cancer 2020 20:170

    Content type: Research article

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  9. Multiple myeloma is a cancer in the bone marrow causing bone destruction. Patients experience various symptoms related to the disease and/or treatment, such as pain and fatigue, leading to poorer quality of li...

    Authors: Rikke Faebo Larsen, Mary Jarden, Lisbeth Rosenbek Minet, Ulf Christian Frølund, Sören Möller and Niels Abildgaard

    Citation: BMC Cancer 2020 20:169

    Content type: Research article

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  10. Overweight/obesity are strongly implicated in breast cancer development, and weight gain post-diagnosis is associated with greater morbidity and all-cause mortality. The aim of this study was to describe the p...

    Authors: Carolyn Ee, Adele Elizabeth Cave, Dhevaksha Naidoo, Kellie Bilinski and John Boyages

    Citation: BMC Cancer 2020 20:113

    Content type: Research article

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  11. Colorectal cancer (CRC) in patients aged under 55 years is on the rise, constituting approximately 10% of cases. Our aim was to determine the survival and clinico-pathological details of young-onset CRC (yCRC)...

    Authors: Sarah Perrott, Kirsten Laurie, Kirsten Laws, Annie Johnes, Zosia Miedzybrodzka and Leslie Samuel

    Citation: BMC Cancer 2020 20:108

    Content type: Research article

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  12. Gliomas consist of a heterogeneous group of tumors. This study aimed to report the incidences of O6-methylguanine-DNA-methyltransferase (MGMT) promoter methylation, 1p19q co-deletion, isocitrate dehydrogenase (ID...

    Authors: Samantha Ya Lyn Ang, Lester Lee, Angela An Qi See, Ting Yao Ang, Beng Ti Ang and Nicolas Kon Kam King

    Citation: BMC Cancer 2020 20:79

    Content type: Research article

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  13. This study aimed to compare clinical outcomes following placement of fully covered self-expanding metallic stents (FCSEMS) vs partially covered self-expanding metallic stents (PCSEMS) for palliative treatment ...

    Authors: Chunmei Wang, Hua Wei and Yuxia Li

    Citation: BMC Cancer 2020 20:73

    Content type: Research article

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  14. Kaposi’s sarcoma (KS) is one of the most common HIV-associated malignancies in sub-Saharan Africa. Worldwide, the availability of antiretroviral therapy (ART) has improved KS survival. In resource-rich setting...

    Authors: Esther E. Freeman, Naftali Busakhala, Susan Regan, Fredrick Chite Asirwa, Megan Wenger, Divya Seth, Khatiya Chelidze Moon, Aggrey Semeere, Toby Maurer, Kara Wools-Kaloustian, Ingrid Bassett and Jeffrey Martin

    Citation: BMC Cancer 2020 20:71

    Content type: Research article

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  15. The precise content and frequency of follow-up of patients with colorectal cancer (CRC) is variable and guideline adherence is low. The aim of this study was to assess the view of colorectal surgeons on their ...

    Authors: S. M. Qaderi, N. A. T. Wijffels, A. J. A. Bremers and J. H. W. de Wilt

    Citation: BMC Cancer 2020 20:22

    Content type: Research article

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  16. Improved, multimodal treatment strategies have been shown to increase cure rates in cancer patients. Those who survive cancer as a child, adolescent or young adult (CAYA), are at a higher risk for therapy-, or...

    Authors: J. Salchow, J. Mann, B. Koch, J. von Grundherr, W. Jensen, S. Elmers, L. A. Straub, E. Vettorazzi, G. Escherich, S. Rutkowski, S. Dwinger, C. Bergelt, M. Sokalska-Duhme, S. Bielack, G. Calaminus, K. Baust…

    Citation: BMC Cancer 2020 20:16

    Content type: Study protocol

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  17. There is absence of literature related to cough prevalence and its characteristics in lung cancer patients, with information deriving only from broader symptoms occurrence studies. The aims of this study were ...

    Authors: Amélie Harle, Alex Molassiotis, Oliver Buffin, Jack Burnham, Jaclyn Smith, Janelle Yorke and Fiona H. Blackhall

    Citation: BMC Cancer 2020 20:9

    Content type: Research article

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  18. Nausea can be particularly prominent during the delayed period. Therefore, we performed a meta-analysis of the available randomised evidence to assess the average effect of palonosetron plus one-day dexamethas...

    Authors: Luigi Celio, Erminio Bonizzoni, Emma Zattarin, Paolo Codega, Filippo de Braud and Matti Aapro

    Citation: BMC Cancer 2019 19:1268

    Content type: Research article

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  19. Previous studies have indicated that accompanying socially underserved cancer patients through Patient Navigator (PN) or PN-derived procedures improves therapy management and reassurance. At the Cancer Institu...

    Authors: K. G. Koffi, D. A. Silué, C. Laurent, K. Boidy, S. Koui, G. Compaci, Z. H. Adeba, I. Kamara, R. P. Botty, A. S. Bognini, I. Sanogo, F. Despas and G. Laurent

    Citation: BMC Cancer 2019 19:1247

    Content type: Research article

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  20. The gut microbiota is an important modulator of immune, metabolic, psychological and cognitive mechanisms. Chemotherapy adversely affects the gut microbiota, inducing acute dysbiosis, and alters physiological ...

    Authors: Julie M. Deleemans, Faye Chleilat, Raylene A. Reimer, Jan-Willem Henning, Mohamad Baydoun, Katherine-Ann Piedalue, Andrew McLennan and Linda E. Carlson

    Citation: BMC Cancer 2019 19:1243

    Content type: Study protocol

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  21. Cervical cancer is a cancer of uterine cervix caused mostly by sexually-acquired infection called Human papillomavirus (HPV. In developing region of the globe, fewer than 50% of women with cervical malignancy ...

    Authors: Mulugeta Wassie, Zeleke Argaw, Yosief Tsige, Mesfin Abebe and Sezer Kisa

    Citation: BMC Cancer 2019 19:1221

    Content type: Research article

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  22. Granulocyte-colony stimulating factor (G-CSF) is increasingly been used to prevent febrile neutropenia (FN) associated with the administration of chemotherapy for various cancers. The most common adverse effec...

    Authors: Hideko Hoshina and Hiroyuki Takei

    Citation: BMC Cancer 2019 19:1217

    Content type: Case report

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  23. On the basis of some significant clinical parameters, we had an intent to establish nomograms for estimating the prognosis of patients with squamous cell carcinoma of the urinary bladder (SCCB), including over...

    Authors: Guanghao Zhang, Zhiwei Li, Daoqing Song and Zhiqing Fang

    Citation: BMC Cancer 2019 19:1200

    Content type: Research article

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  24. Hormone replacement therapy (HRT) use has shown to be associated with a reduced risk of colorectal cancer, however, its impact on survival among women with colorectal cancer remains uncertain. This meta-analys...

    Authors: Yeu-Chai Jang, Hsi-Lan Huang and Chi Yan Leung

    Citation: BMC Cancer 2019 19:1199

    Content type: Research article

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  25. Previous studies have suggested that lymphoma survivors commonly display altered Health-Related Quality of Life (HRQoL). Because these were predominantly cross-sectional studies, the dynamic of events as well ...

    Authors: Gisèle Compaci, Cécile Conte, Lucie Oberic, Loïc Ysebaert, Guy Laurent and Fabien Despas

    Citation: BMC Cancer 2019 19:1178

    Content type: Research article

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  26. Half of cancer cases occur in patients aged 70 and above. Majority of older patients are eligible for chemotherapy but evidence for treating this population is sparse and severe toxicities affect more than hal...

    Authors: Zara Steinmeyer, Stéphane Gérard, Thomas Filleron, Stéphanie Lozano, Delphine Brechemier, Gabor Abellan Van Kan, Loic Mourey, Laurence Cristol-Dalstein, Laure De Decker, Yves Rolland and Laurent Balardy

    Citation: BMC Cancer 2019 19:1153

    Content type: Study protocol

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  27. Chemotherapy-induced peripheral neuropathy (CIPN) is common among cancer patients treated with neurotoxic chemotherapy agents. Better knowledge on symptom clusters of CIPN may help improve symptom management i...

    Authors: Mian Wang, Hui Lin Cheng, Violeta Lopez, Raghav Sundar, Janelle Yorke and Alex Molassiotis

    Citation: BMC Cancer 2019 19:1151

    Content type: Research article

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  28. The aim of this study was to analyze biopsychosocial factors affecting how patients cope with cancer and adjuvant treatment and to appraise psychological distress, coping, perceived social support, quality of ...

    Authors: Teresa García-García, Alberto Carmona-Bayonas, Paula Jimenez-Fonseca, Carlos Jara, Carmen Beato, Beatriz Castelo, Montserrat Mangas, Eva Martínez de Castro, Avinash Ramchandani, David Gomez and Caterina Calderón

    Citation: BMC Cancer 2019 19:1143

    Content type: Research article

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  29. To measure changes in four common chemotherapy related side-effects (low energy, stress, nausea and pain) immediately after a single exercise session within the first week after treatment.

    Authors: Anna Johnsson, Ingrid Demmelmaier, Katarina Sjövall, Philippe Wagner, Håkan Olsson and Åsa B. Tornberg

    Citation: BMC Cancer 2019 19:1073

    Content type: Research article

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  30. Although numerous studies have investigated the clinicopathologic and prognostic relevance of mucinous adenocarcinoma (MAC) and signet-ring cell carcinoma (SRCC) compared with classic adenocarcinoma (CA), litt...

    Authors: Hui Sheng, Xiaoli Wei, Minjie Mao, Jincan He, Tianqi Luo, Shilin Lu, Liye Zhou, Zhixin Huang and Anli Yang

    Citation: BMC Cancer 2019 19:1071

    Content type: Research article

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  31. Three-weekly high-dose cisplatin (100 mg/m2) is considered the standard systemic regimen given concurrently with postoperative or definitive radiotherapy in locally advanced squamous cell carcinoma of the head an...

    Authors: Maurice J. D. L. van der Vorst, Elisabeth C. W. Neefjes, Elisa C. Toffoli, Jolanda E. W. Oosterling-Jansen, Marije R. Vergeer, C. René Leemans, Menno P. Kooistra, Jens Voortman and Henk M. W. Verheul

    Citation: BMC Cancer 2019 19:1066

    Content type: Research article

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  32. Prostate cancer is one of the most common cancers in the world. The results of treatment after hypofractionated radiotherapy only have been reported from several small randomized clinical trials. Therefore, we...

    Authors: Wei Guo, Yun-Chuan Sun, Jian-Qiang Bi, Xin-Ying He and Li Xiao

    Citation: BMC Cancer 2019 19:1063

    Content type: Research article

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  33. In oncology, Health Care Professionals often experience conducting Advance Care Planning (ACP) conversations as difficult and are hesitant to start them. A structured approach could help to overcome this. In t...

    Authors: M. Zwakman, K. Pollock, F. Bulli, G. Caswell, B. Červ, J. J. M. van Delden, L. Deliens, A. van der Heide, L. J. Jabbarian, H. Koba-Čeh, U. Lunder, G. Miccinesi, C. A. Møller Arnfeldt, J. Seymour, A. Toccafondi, M. N. Verkissen…

    Citation: BMC Cancer 2019 19:1026

    Content type: Research article

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  34. Accumulating evidence suggests that Gamma-glutamyltransferase (GGT) may be involved in cancer occurrence and progression. However, the prognostic role of serum GGT in pancreatic cancer (PC) survival lacks adeq...

    Authors: Yuanyuan Xiao, Haijun Yang, Jian Lu, Dehui Li, Chuanzhi Xu and Harvey A. Risch

    Citation: BMC Cancer 2019 19:1020

    Content type: Research article

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  36. Quality of life among prostate cancer survivors varies by socio-demographic factors and treatment type received; however, less in known about differences in functional outcomes by method of presentation. We in...

    Authors: David W. Donnelly, Linda C. Vis, Therese Kearney, Linda Sharp, Damien Bennett, Sarah Wilding, Amy Downing, Penny Wright, Eila Watson, Richard Wagland, William R. Cross, Malcolm D. Mason, Sabine Siesling, Jeannette G. van Manen, Adam W. Glaser and Anna Gavin

    Citation: BMC Cancer 2019 19:947

    Content type: Research article

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  37. A cancer diagnosis can have a substantial impact on mental health and wellbeing. Depression and anxiety may hinder cancer treatment and recovery, as well as quality of life and survival. We argue that more res...

    Authors: Claire L. Niedzwiedz, Lee Knifton, Kathryn A. Robb, Srinivasa Vittal Katikireddi and Daniel J. Smith

    Citation: BMC Cancer 2019 19:943

    Content type: Debate

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  38. Appropriate assessment is essential for the management of chemotherapy-induced peripheral neuropathy (CIPN), an intractable symptom that cannot yet be palliated, which is high on the list of causes of distress...

    Authors: K. Kanda, K. Fujimoto, R. Mochizuki, K. Ishida and B. Lee

    Citation: BMC Cancer 2019 19:904

    Content type: Research article

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  39. Suffering from cancer confronts both the patient and their partner with a number of psychosocial challenges in various aspects of their life. These challenges may differentially impact on quality of life, copi...

    Authors: Inga Lorenz, Daniela Bodschwinna, Nina Hallensleben, Hartmut Döhner, Dietger Niederwieser, Tanja Zimmermann, Anja Mehnert, Harald Gündel, Jochen Ernst and Klaus Hoenig

    Citation: BMC Cancer 2019 19:885

    Content type: Study protocol

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  40. Population-based studies suggest that emergency department visits and hospitalizations are common among patients receiving chemotherapy and that rates in routine practice are higher than expected from clinical...

    Authors: Monika K. Krzyzanowska, Jim A. Julian, Melanie Powis, Doris Howell, Craig C. Earle, Katherine A. Enright, Nicole Mittmann, Maureen E. Trudeau and Eva Grunfeld

    Citation: BMC Cancer 2019 19:884

    Content type: Study protocol

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  41. Trauma- and stressor-related disorders pose an important threat for patients with medical conditions by negatively affecting the outcomes of the underlying somatic disease. Nevertheless, research on distress i...

    Authors: Peter Esser, Katharina Kuba, Jochen Ernst and Anja Mehnert-Theuerkauf

    Citation: BMC Cancer 2019 19:870

    Content type: Study protocol

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  42. Identification of specific needs in patients with cancer is very important for the provision of patient-centered medical service. The aim of this study was to investigate the unmet needs and related factors of...

    Authors: Byung Joo Chae, Jihyoun Lee, Se Kyung Lee, Hyuk-Jae Shin, So-Youn Jung, Jong Won Lee, Zisun Kim, Min Hyuk Lee, Juhyung Lee and Hyun Jo Youn

    Citation: BMC Cancer 2019 19:839

    Content type: Research article

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  43. Depression is a common co-morbid, disabling disorder that affects 10–25% of cancer patients. It causes substantial functional impairment and lowers survival rate of breast cancer patients. Therefore, the aim o...

    Authors: Abigiya Wondimagegnehu, Workeabeba Abebe, Aynalem Abraha and Solomon Teferra

    Citation: BMC Cancer 2019 19:836

    Content type: Research article

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  44. Sexuality is an important aspect of quality of life for adolescent and young adults that remains understudied in cancer patients. Most current knowledge about how cancer and cancer treatments can affect patien...

    Authors: Julian Mütsch, Michael Friedrich, Katja Leuteritz, Annekathrin Sender, Kristina Geue, Anja Hilbert and Yve Stöbel-Richter

    Citation: BMC Cancer 2019 19:828

    Content type: Research article

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  45. Diets that restrict energy or macronutrient intake (e.g. fasting/ketogenic diets (KDs)) may selectively protect non-tumour cells during cancer treatment. Previous reviews have focused on a subset of dietary re...

    Authors: Ellie Shingler, Rachel Perry, Alexandra Mitchell, Clare England, Claire Perks, Georgia Herbert, Andy Ness and Charlotte Atkinson

    Citation: BMC Cancer 2019 19:811

    Content type: Research article

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  46. Communication between health care provider and patients in oncology presents challenges. Communication skills training have been frequently developed to address those. Given the complexity of communication tra...

    Authors: F. Fischer, S. Helmer, A. Rogge, J. I. Arraras, A. Buchholz, A. Hannawa, M. Horneber, A. Kiss, M. Rose, W. Söllner, B. Stein, J. Weis, P. Schofield and C. M. Witt

    Citation: BMC Cancer 2019 19:808

    Content type: Research article

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  47. The prognostic role of serum alkaline phosphatase (ALP) has been found in several kinds of solid malignant tumor, but has never been extensively discussed in pancreatic cancer, especially through the applicati...

    Authors: Yuanyuan Xiao, Jian Lu, Wei Chang, Ying Chen, Xiaomei Li, Dehui Li, Chuanzhi Xu and Haijun Yang

    Citation: BMC Cancer 2019 19:785

    Content type: Research article

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  48. Adjunct testosterone therapy improves lean body mass, quality of life, and physical activity in patients with advanced cancers; however, the effects of testosterone on cardiac morphology and function are unkno...

    Authors: Jessica M. Scott, E. Lichar Dillon, Michael Kinsky, Albert Chamberlain, Susan McCammon, Daniel Jupiter, Maurice Willis, Sandra Hatch, Gwyn Richardson, Christopher Danesi, Kathleen Randolph, William Durham, Traver Wright, Randall Urban and Melinda Sheffield-Moore

    Citation: BMC Cancer 2019 19:778

    Content type: Research article

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  49. Worldwide, over 500,000 people are diagnosed with head and neck cancer each year, a disease with major impact on life expectancy and quality of life. The purpose of the Netherlands Quality of life and Biomedic...

    Authors: I.M. Verdonck-de Leeuw, F. Jansen, R. H. Brakenhoff, J. A. Langendijk, R. Takes, C. H. J. Terhaard, R. J. Baatenburg de Jong, J. H. Smit and C. R. Leemans

    Citation: BMC Cancer 2019 19:765

    Content type: Study protocol

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    The Correction to this article has been published in BMC Cancer 2019 19:982

  50. Patients with breast cancer undergoing chemotherapy and radiotherapy experience fatigue and other treatment side effects. Integrative therapies combining physical activity and dietary counseling are recommende...

    Authors: Marion Carayol, Gregory Ninot, Pierre Senesse, Jean-Pierre Bleuse, Sophie Gourgou, Hélène Sancho-Garnier, Chakib Sari, Isabelle Romieu, Gilles Romieu and William Jacot

    Citation: BMC Cancer 2019 19:737

    Content type: Research article

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