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Surgical oncology, cancer imaging, and interventional therapeutics

Section edited by Stephen P. Povoski

This section focuses on clinical research that impacts on the diagnosis and treatment of cancer using surgery, diagnostic imaging, interventional therapeutics, and surgical pathology.

Page 8 of 10

  1. Content type: Research article

    In the early stage esophageal cancer, changes in the mucosa are subtle and pass unnoticed in endoscopic examinations using white light. To increase sensitivity, chromoscopy with Lugol’s solution has been used....

    Authors: Flavio Hiroshi Ananias Morita, Wanderley Marques Bernardo, Edson Ide, Rodrigo Silva Paula Rocha, Julio Cesar Martins Aquino, Mauricio Kazuyoshi Minata, Kendi Yamazaki, Sergio Barbosa Marques, Paulo Sakai and Eduardo Guimarães Hourneaux de Moura

    Citation: BMC Cancer 2017 17:54

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  2. Content type: Case report

    Long-term term survival in patients with pancreatic neuroendocrine tumors has been reported, even in patients with metastatic disease. Metastases to the spleen are extremely rare, but have been reported from a...

    Authors: Yasunaru Sakuma, Yoshikazu Yasuda, Naohiro Sata, Yoshinori Hosoya, Atsushi Shimizu, Hirofumi Fujii, Daisuke Matsubara, Noriyuki Fukushima, Atsushi Miki, Misato Maeno and Alan Kawarai Lefor

    Citation: BMC Cancer 2017 17:37

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  3. Content type: Research article

    Preoperative neoadjuvant therapy for colorectal liver metastases (CRLM) is increasing in use and can lead to chemotherapy-induced damage to sinusoidal integrity, namely sinusoidal obstruction syndrome (SOS). S...

    Authors: Heather L. Stevenson, Mariana M. Prats and Eizaburo Sasatomi

    Citation: BMC Cancer 2017 17:35

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  4. Content type: Research article

    The Hangzhou criteria expand the Milan criteria safely and effectively in selecting hepatocellular carcinoma (HCC) candidates for liver transplantation (LT), but some patients exceeding the Milan but fulfillin...

    Authors: Weiliang Xia, Qinghong Ke, Hua Guo, Weilin Wang, Min Zhang, Yan Shen, Jian Wu, Xiao Xu, Sheng Yan, Jun Yu, Mangli Zhang and Shusen Zheng

    Citation: BMC Cancer 2017 17:14

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  5. Content type: Research article

    To investigate the impact of biological gender on operative parameters, especially operative time, in laparoscopic partial nephrectomy (LPN) for T1 renal tumor.

    Authors: Hiroki Ito, Kazuhide Makiyama, Takashi Kawahara, Kimito Osaka, Koji Izumi, Yumiko Yokomizo, Noboru Nakaigawa and Masahiro Yao

    Citation: BMC Cancer 2016 16:944

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  6. Content type: Research article

    Prognostic factors aid in the stratification and treatment of cancer. This study evaluated the prognostic significance of human epidermal growth factor receptor (HER) family members (HER1–4) expression in pati...

    Authors: Qin Li, Lei Zhang, XiuHong Li, Han Yan, Liuting Yang, Yingying Li, Teng Li, Jing Wang and Bangwei Cao

    Citation: BMC Cancer 2016 16:910

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  7. Content type: Research article

    Evaluation of resection margins during cancer surgery can be challenging, often resulting in incomplete tumour removal. Fluorescence-guided surgery (FGS) aims to aid the surgeon to visualize tumours and resect...

    Authors: P. B. A. A. van Driel, M. C. Boonstra, H. A. J. M. Prevoo, M. van de Giessen, T. J. A. Snoeks, Q. R. J. G. Tummers, S. Keereweer, R. A. Cordfunke, A. Fish, J. D. H. van Eendenburg, B. P. F. Lelieveldt, J. Dijkstra, C. J. H. van de Velde, P. J. K. Kuppen, A. L. Vahrmeijer, C. W. G. M. Löwik…

    Citation: BMC Cancer 2016 16:884

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  8. Content type: Research article

    Evaluation of lymph node involvement is an important factor in detecting metastasis and deciding whether to perform axillary lymph node dissection (ALND) in breast cancer surgery. As ALND is associated with po...

    Authors: Kelsey M. Kennedy, Lixin Chin, Philip Wijesinghe, Robert A. McLaughlin, Bruce Latham, David D. Sampson, Christobel M. Saunders and Brendan F. Kennedy

    Citation: BMC Cancer 2016 16:874

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  9. Content type: Research article

    The purpose of this study is to review our results for pancreatic resection in patients with intraductal papillary mucinous neoplasm (IPMN) with and without associated carcinoma.

    Authors: Katharina Marsoner, Johannes Haybaeck, Dora Csengeri, James Elvis Waha, Jakob Schagerl, Rainer Langeder, Hans Joerg Mischinger and Peter Kornprat

    Citation: BMC Cancer 2016 16:844

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  10. Content type: Case report

    Myoepithelial carcinoma (MEC) is a rare salivary gland tumor. Its long-term prognosis remains unknown because of the paucity of reported cases with long-term follow-up. Although some case series exist, the cli...

    Authors: Takahiro Wakasaki, Marie Kubota, Yutaka Nakashima, Eri Tomonobe, Takenao Mihara and Junichi Fukushima

    Citation: BMC Cancer 2016 16:827

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  11. Content type: Research article

    To evaluate the accuracy of sentinel lymph node biopsy (SLNB) after neoadjuvant chemotherapy (NAC) in breast cancer patients with axillary lymph node (ALN) metastasis.

    Authors: Yue Yu, Ning Cui, Heng-Yu Li, Yan-Mei Wu, Lu Xu, Min Fang and Yuan Sheng

    Citation: BMC Cancer 2016 16:808

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  12. Content type: Case report

    Gemcitabine is currently the standard chemotherapy for the adjuvant treatment of pancreatic cancer. This chemotherapeutic agent is generally well-tolerated, myelosuppression and gastrointestinal toxicity being...

    Authors: Elisabetta Fenocchio, Ilaria Depetris, Delia Campanella, Lucia Garetto, Fabrizio Carnevale Schianca, Danilo Galizia, Giovanni Grignani, Massimo Aglietta and Francesco Leone

    Citation: BMC Cancer 2016 16:793

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  13. Content type: Case report

    Pancreatic cancer is among the top 5 most common cancers worldwide, but is particularly devastating due to its insidious nature. Complete surgical resection remains the only potential curative treatment, altho...

    Authors: Mišo Gostimir, Sean Bennett, Terence Moyana, Harman Sekhon and Guillaume Martel

    Citation: BMC Cancer 2016 16:786

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  14. Content type: Research article

    Surgery for advanced gastric cancer (AGC) often includes dissection of splenic hilar lymph nodes (SHLNs). This study compared the safety and effectiveness of different approaches to SHLN dissection for upper- ...

    Authors: Xin Ji, Tao Fu, Zhao-De Bu, Ji Zhang, Xiao-Jiang Wu, Xiang-Long Zong, Zi-Yu Jia, Biao Fan, Yi-Nan Zhang and Jia-Fu Ji

    Citation: BMC Cancer 2016 16:765

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  15. Content type: Research article

    Arterial hyperenhancement and washout on computed tomography and magnetic resonance imaging (MRI) are described by all major guidelines as specific criteria for non-invasive diagnosis of hepatocellular carcino...

    Authors: Roman Kloeckner, Daniel Pinto dos Santos, Karl-Friedrich Kreitner, Anne Leicher-Düber, Arndt Weinmann, Jens Mittler and Christoph Düber

    Citation: BMC Cancer 2016 16:758

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  16. Content type: Research article

    A totally implantable venous access device (TIVAD) provides reliable, long-term vascular access and improves patients’ quality of life. The wide use of TIVADs is associated with important complications. A meta...

    Authors: Shaoyong Wu, Jingxiu Huang, Zongming Jiang, Zhimei Huang, Handong Ouyang, Li Deng, Wenqian Lin, Jin Guo and Weian Zeng

    Citation: BMC Cancer 2016 16:747

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  17. Content type: Research article

    Sequential biopsy of breast cancer is used to assess biomarker effects and drug efficacy. The preoperative “window of opportunity” setting is advantageous to test biomarker changes in response to therapeutic a...

    Authors: Sirwan M. Hadad, Lee B. Jordan, Pankaj G. Roy, Colin A. Purdie, Takayuki Iwamoto, Lajos Pusztai, Stacy L. Moulder-Thompson and Alastair M. Thompson

    Citation: BMC Cancer 2016 16:745

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  18. Content type: Research article

    The incidence rate has been increasing for superficial head and neck squamous cell carcinoma (HNSCC) discovered through surveillance endoscopic study using narrow band imaging (NBI), a procedure mainly used fo...

    Authors: Hiroshi Nakamura, Tomonori Yano, Satoshi Fujii, Tomohiro Kadota, Toshifumi Tomioka, Takeshi Shinozaki, Ryuichi Hayashi and Kazuhiro Kaneko

    Citation: BMC Cancer 2016 16:743

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  19. Content type: Research article

    In Germany, most breast cancer patients are treated in specialized breast cancer units (BCU), which are certified, and routinely monitored. Herein, we evaluate up-to-date oncological outcome of breast cancer (...

    Authors: André Hennigs, Fabian Riedel, Adam Gondos, Peter Sinn, Peter Schirmacher, Frederik Marmé, Dirk Jäger, Hans-Ulrich Kauczor, Anne Stieber, Katja Lindel, Jürgen Debus, Michael Golatta, Florian Schütz, Christof Sohn, Jörg Heil and Andreas Schneeweiss

    Citation: BMC Cancer 2016 16:734

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  20. Content type: Case report

    Lung cancer is usually presented with cough, dyspnea, pain and weight loss, which is overlapping with symptoms of other lung diseases such as pulmonary fibrosis. Pulmonary fibrosis shows characteristic reticul...

    Authors: Bakir Mehić, Lina Duranović Rayan, Nurija Bilalović, Danina Dohranović Tafro and Ilijaz Pilav

    Citation: BMC Cancer 2016 16:729

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  21. Content type: Research article

    The purpose of this study was to investigate the impact of the Controlling Nutritional Status (CONUT) score on survival compared with the platelet to lymphocyte ratio (PLR), the neutrophil to lymphocyte ratio ...

    Authors: Takahiro Toyokawa, Naoshi Kubo, Tatsuro Tamura, Katsunobu Sakurai, Ryosuke Amano, Hiroaki Tanaka, Kazuya Muguruma, Masakazu Yashiro, Kosei Hirakawa and Masaichi Ohira

    Citation: BMC Cancer 2016 16:722

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  22. Content type: Research article

    The role of laparoscopic resection in patients with clinically suspicious T4 colorectal cancer remains controversial. The aim of this study was to compare the long-term and oncologic outcomes of laparoscopic r...

    Authors: Jong Seob Park, Jung Wook Huh, Yoon Ah Park, Yong Beom Cho, Seong Hyeon Yun, Hee Cheol Kim, Woo Yong Lee and Ho-Kyung Chun

    Citation: BMC Cancer 2016 16:714

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  23. Content type: Case report

    Hepatocellular carcinoma (HCC) patients with hepatic vein tumor thrombosis (HVTT) extending to the inferior vena cava (IVC) have an extremely poor prognosis. Here we report a case of HCC with HVTT and renal dy...

    Authors: Atene Itoh, Hiroshi Sadamori, Kazuhisa Yabushita, Kazuteru Monden, Masashi Tatsukawa, Masayoshi Hioki, Tsuyoshi Hyodo, Kunihiro Omonishi, Toru Ueki, Satoshi Ohno, Kohsaku Sakaguchi and Norihisa Takakura

    Citation: BMC Cancer 2016 16:705

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  24. Content type: Study protocol

    The efficacy of the classical treatment modalities surgery and radiotherapy in the treatment of aggressive fibromatosis is presently disputed and there is a shift towards a more conservative approach. The aim ...

    Authors: Danique L.M. van Broekhoven, Dirk J. Grünhagenl, Thijs van Dalen, Frits van Coevorden, Han J. Bonenkamp, Lukas B. Been, Marc H.A. Bemelmans, Sander D.S. Dijkstra, Chiara Colombo, Alessandro Gronchi and Cornelis Verhoef

    Citation: BMC Cancer 2016 16:686

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  25. Content type: Research article

    The aims of this study were to evaluate the impact of initial uterus-preserving surgery, such as myomectomy or subtotal hysterectomy, on the recurrence rates of patients with uterine sarcoma found incidentally...

    Authors: Jung-Yun Lee, Hyun Soo Kim, Eun Ji Nam, Sang Wun Kim, Sunghoon Kim and Young Tae Kim

    Citation: BMC Cancer 2016 16:675

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  26. Content type: Research article

    The Response Evaluation Criteria in Solid Tumors (RECIST) are the current standard for evaluating disease progression or therapy response in patients with solid tumors. RECIST 1.1 calls for axial, longest-diam...

    Authors: Kathleen E. Fenerty, Les R. Folio, Nicholas J. Patronas, Jennifer L. Marté, James L. Gulley and Christopher R. Heery

    Citation: BMC Cancer 2016 16:672

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  27. Content type: Research article

    The predictive accuracy of the American Joint Committee on Cancer (AJCC) stages of colorectal cancer (CRC) is mediocre. This study aimed to develop postoperative nomograms to predict cancer-specific survival (...

    Authors: Zhen-yu Zhang, Qi-feng Luo, Xiao-wei Yin, Zhen-ling Dai, Shiva Basnet and Hai-yan Ge

    Citation: BMC Cancer 2016 16:658

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  28. Content type: Research article

    Methotrexate-associated lymphoproliferative disorder (MTX-LPD) is a benign lymphoid proliferation or malignant lymphoma in patients who have been treated with MTX. MTX withdrawal and observation for a short pe...

    Authors: Shiro Watanabe, Osamu Manabe, Kenji Hirata, Noriko Oyama-Manabe, Naoya Hattori, Yasuka Kikuchi, Kentaro Kobayashi, Takuya Toyonaga and Nagara Tamaki

    Citation: BMC Cancer 2016 16:635

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  29. Content type: Research article

    Variable degrees of differentiation in hepatocellular carcinoma(HCC)under Edmondson-Steiner grading system has been proven to be an independent prognostic indicator for HCC. Up till now, there has been no effe...

    Authors: Zhenpeng Peng, Mengjie Jiang, Huasong Cai, Tao Chan, Zhi Dong, Yanji Luo, Zi-Ping Li and Shi-Ting Feng

    Citation: BMC Cancer 2016 16:625

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  30. Content type: Research article

    The response to neoadjuvant chemotherapy has been proven to predict long-term clinical benefits for patients. Our research is to construct a nomogram to predict pathological complete response of human epiderma...

    Authors: Xi Jin, Yi-Zhou Jiang, Sheng Chen, Ke-Da Yu, Ding Ma, Wei Sun, Zhi-Min Shao and Gen-Hong Di

    Citation: BMC Cancer 2016 16:606

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  31. Content type: Study protocol

    Lymphedema is a prevalent long-term effect of breast cancer treatment that is associated with reduced quality of life. More recent observational data suggest that the addition of night-time compression to day-...

    Authors: Margaret L. McNeely, Kristin L. Campbell, Marc Webster, Urve Kuusk, Karen Tracey and John Mackey

    Citation: BMC Cancer 2016 16:601

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  32. Content type: Case report

    In the lung, melanoma is mostly arranged as patterns of multiple nodules, solitary nodules, or miliary invasions. Very rarely, it also displays a “crazy paving” pattern (also described as a “paving stone,” “fl...

    Authors: Yikuan Feng, Jianping Zhao, Qun Yang, Weining Xiong, Guohua Zhen, Yongjian Xu, Zhenxiang Zhang and Huilan Zhang

    Citation: BMC Cancer 2016 16:592

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  33. Content type: Research article

    Liver biopsies in pediatric hematopoietic stem cell transplantation (HSCT) patients are as and effective when performed at bedside in the Bone Marrow Transplant Unit (BMTU) than in the Day Surgery Unit (DSU), ...

    Authors: Natalia Maximova, Massimo Gregori, Francesca Barbieri, Antonio Pizzol and Aurelio Sonzogni

    Citation: BMC Cancer 2016 16:590

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  34. Content type: Study protocol

    Total laryngectomy with or without adjuvant (chemo)radiation often induces speech, swallowing and neck and shoulder problems. Speech, swallowing and shoulder exercises may prevent or diminish these problems. T...

    Authors: Femke Jansen, Ingrid C. Cnossen, Simone E. J. Eerenstein, Veerle M. H. Coupé, Birgit I. Witte, Cornelia F. van Uden-Kraan, Patricia Doornaert, Weibel W. Braunius, Remco De Bree, José A. U. Hardillo, Jimmie Honings, György B. Halmos, C. René Leemans and Irma M. Verdonck-de Leeuw

    Citation: BMC Cancer 2016 16:580

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  35. Content type: Research article

    Volume-based parameters, such as metabolic tumor volume (MTV) and total lesion glycolysis (TLG), on F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) are useful for predicting treatment response...

    Authors: Tomoka Kitao, Kenji Hirata, Katsumi Shima, Takashi Hayashi, Mitsunori Sekizawa, Toshiki Takei, Wataru Ichimura, Masao Harada, Keishi Kondo and Nagara Tamaki

    Citation: BMC Cancer 2016 16:576

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  36. Content type: Research article

    The distinction between right-sided and left-sided colon cancer has recently received considerable attention due to differences regarding underlying genetic mutations. There is an ongoing debate if right- vers...

    Authors: Rene Warschkow, Michael C. Sulz, Lukas Marti, Ignazio Tarantino, Bruno M. Schmied, Thomas Cerny and Ulrich Güller

    Citation: BMC Cancer 2016 16:554

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  37. Content type: Research article

    Ganglioneuroma (GN) and ganglioneuroblastoma intermixed (GNBI) are mature variants of neuroblastic tumors (NT). It is still discussed whether incomplete resection of GN/GNBI impairs the outcome of patients.

    Authors: Boris Decarolis, Thorsten Simon, Barbara Krug, Ivo Leuschner, Christian Vokuhl, Peter Kaatsch, Dietrich von Schweinitz, Thomas Klingebiel, Ingo Mueller, Lothar Schweigerer, Frank Berthold and Barbara Hero

    Citation: BMC Cancer 2016 16:542

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  38. Content type: Research article

    Prostate cancer (PC) is a major health concern for men worldwide, with an estimated lifetime risk of ~14 %. A recent comprehensive analysis of mutational processes revealed ageing and mismatch repair as the on...

    Authors: Lynne Kerr, Matthew J. Rewhorn, Mark Longmuir, Sioban Fraser, Shaun Walsh, Nicola Andrew and Hing Y. Leung

    Citation: BMC Cancer 2016 16:529

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  39. Content type: Research article

    Binding to Sema4D and PlexinB1 induce angiogenesis and invasive growth in colorectal cancer (CRC). The expression of Semaphorin4D (Sema4D) and PlexinB1 has been shown to be related to the prognosis of patients...

    Authors: Tetsuro Ikeya, Kiyoshi Maeda, Hisashi Nagahara, Masatsune Shibutani, Yasuhito Iseki and Kosei Hirakawa

    Citation: BMC Cancer 2016 16:525

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  40. Content type: Research article

    The chemokine CXCL12 and its corresponding receptor CXCR4 are key players in the development of several cancers. Therefore, we hypothesized that there is a functional causality between CXCL12 expression and tu...

    Authors: Yusuke Uchi, Hiroya Takeuchi, Sachiko Matsuda, Yoshiro Saikawa, Hirofumi Kawakubo, Norihito Wada, Tsunehiro Takahashi, Rieko Nakamura, Kazumasa Fukuda, Tai Omori and Yuko Kitagawa

    Citation: BMC Cancer 2016 16:514

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  41. Content type: Study protocol

    Rectal cancer surgery is accompanied with high morbidity and poor long term functional outcome. Screening programs have shown a shift towards more early staged cancers. Patients with early rectal cancer can po...

    Authors: W. A. A. Borstlap, P. J. Tanis, T. W. A. Koedam, C. A. M. Marijnen, C. Cunningham, E. Dekker, M. E. van Leerdam, G. Meijer, N. van Grieken, I. D. Nagtegaal, C. J. A. Punt, M. G. W. Dijkgraaf, J. H. De Wilt, G. Beets, E. J. de Graaf, A. A. W van Geloven…

    Citation: BMC Cancer 2016 16:513

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  42. Content type: Research article

    Synovial sarcoma (SS) is a soft tissue sarcoma of unknown histogenesis. Most metastatic or unresectable cases are incurable. Novel antitumor agents and precise prognostication are needed for SS patients. The p...

    Authors: Akira Maekawa, Kenichi Kohashi, Masaaki Kuda, Kunio Iura, Takeaki Ishii, Makoto Endo, Tetsuya Nakatsura, Yukihide Iwamoto and Yoshinao Oda

    Citation: BMC Cancer 2016 16:511

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  43. Content type: Research article

    Occult invasive cervical cancer (OICC) is sometimes incidentally found in surgical specimens after a simple hysterectomy (SH). This study was aimed at identifying a subset of patients with OICC who have a favo...

    Authors: Huimin Bai, Dongyan Cao, Fang Yuan, Huilan Wang, Jie Chen, Yue Wang, Keng Shen and Zhenyu Zhang

    Citation: BMC Cancer 2016 16:507

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  44. Content type: Research article

    This study was carried out to determine the prognostic significance of preoperative peripheral epithelial cell adhesion molecule- positive (EpCAM +) circulating tumor cell (CTC) and T ...

    Authors: Yan Zhou, Beili Wang, Jiong Wu, Chunyan Zhang, Yiwen Zhou, XinRong Yang, Jian Zhou, Wei Guo and Jia Fan

    Citation: BMC Cancer 2016 16:506

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  45. Content type: Research article

    The 2010 guidelines of the French National Cancer Institute (INCa) classify patients with endometrial cancer into three risk groups for lymph node invasion and recurrence on the basis of MRI and histological a...

    Authors: Noemie Body, Vincent Lavoué, Olivier De Kerdaniel, Fabrice Foucher, Sébastien Henno, Aurélie Cauchois, Bruno Laviolle, Marc Leblanc and Jean Levêque

    Citation: BMC Cancer 2016 16:498

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  46. Content type: Research article

    The purpose of this retrospective study was to evaluate the efficacy of incorporating trans-arterial radioembolization (TARE) with systemic chemotherapy in the treatment of liver-dominant metastatic pancreatic...

    Authors: Alexander Y. Kim, Keith Unger, Hongkun Wang and Michael J. Pishvaian

    Citation: BMC Cancer 2016 16:492

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