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Surgical oncology, cancer imaging, and interventional therapeutics

Section edited by Stephen P. Povoski

This section focuses on clinical research that impacts on the diagnosis and treatment of cancer using surgery, diagnostic imaging, interventional therapeutics, and surgical pathology.

Page 5 of 12

  1. Dexamethasone is widely used in cancer patients despite the concern that perioperative glucocorticoids may potentially cause immunosuppression. However, studies on the influence of dexamethasone on cancer recu...

    Authors: Myoung Hwa Kim, Dong Wook Kim, Seho Park, Joo Heung Kim, Ki Young Lee, Jisung Hwang and Young Chul Yoo

    Citation: BMC Cancer 2019 19:251

    Content type: Research article

    Published on:

  2. Nonseminomatous germ cell tumors (NSGCTs) represent one of the main groups of germ cell tumors (GCTs), and they have a more invasive course than seminomatous GCTs. Human immunodeficiency virus (HIV) positivity...

    Authors: Ruili Li and Hongjun Li

    Citation: BMC Cancer 2019 19:244

    Content type: Case report

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  3. Perivascular Epithelioid Cell Tumors (PEComa) is an extraordinarily rare mesenchymal neoplasm especially the malignant type originating from the lung. To date, only 8 cases of malignant or malignant potential ...

    Authors: Jikai Zhao, Haohua Teng, Ruiying Zhao, Wenjie Ding, Keke Yu, Lei Zhu, Jie Zhang and Yuchen Han

    Citation: BMC Cancer 2019 19:235

    Content type: Case report

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  4. Glucose metabolism has been suggested as a therapeutic target in ovarian clear cell carcinoma (CCC). We attempted to clarify 18F-FDG PET/CT-based metabolic metrics in the recurrent ovarian CCC patients and their ...

    Authors: Shuang Ye, Shuai Liu, Libing Xiang, Xiaohua Wu and Huijuan Yang

    Citation: BMC Cancer 2019 19:226

    Content type: Research article

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  5. 0.17–2% of mature cystic teratoma of the ovary (MCTO) undergo malignant transformation, of which 80% are squamous cell carcinoma (SCC) transformation in MCTO. We aim to investigate the clinical characteristics...

    Authors: Congcong Li, Qing Zhang, Siying Zhang, Ruifen Dong, Chenggong Sun, Chunping Qiu, Zhiwei Zhang, Xingsheng Yang and Beihua Kong

    Citation: BMC Cancer 2019 19:217

    Content type: Research article

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  6. This study sought to explore whether lymphovascular invasion can affect the prognosis of patients with stage N0 gastric cancer and to evaluate the survival benefit of adjuvant chemotherapy for such patients.

    Authors: Jun Lu, Yun Dai, Jian-Wei Xie, Jia-Bin Wang, Jian-Xian Lin, Qi-Yue Chen, Long-Long Cao, Mi Lin, Ru-Hong Tu, Chao-Hui Zheng, Ping Li and Chang-Ming Huang

    Citation: BMC Cancer 2019 19:216

    Content type: Research article

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  7. Tumor-associated lymphangiogenesis is considered significant in number of solid malignancies. However, its impact on prognosis of intrahepatic cholangiocarcinoma (ICC) after resection remains further confirmat...

    Authors: Meng Sha, Seogsong Jeong, Xin Wang, Ying Tong, Jie Cao, Han-Yong Sun, Lei Xia, Ning Xu, Zhi-Feng Xi, Jian-Jun Zhang, Xiao-Ni Kong and Qiang Xia

    Citation: BMC Cancer 2019 19:208

    Content type: Research article

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  8. KLASS (the Korean Laparoendoscopic Gastrointestinal Surgery Study) is a time-honored study group that has established laparoscopic surgery for gastrointestinal disease in Korea and has performed some important...

    Authors: Chang Min Lee, Ji Ho Park, Chang In Choi, Han Hong Lee, Jae-Seok Min, Ye Seob Jee, Oh. Jeong, Hyundong Chae, Sung Il Choi, Hua Huang and Sungsoo Park

    Citation: BMC Cancer 2019 19:206

    Content type: Study protocol

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  9. Primary cardiac lymphomas (PCL) represent extremely rare cardiac tumors which are accompanied by poor prognosis, unless they are timely diagnosed and treated.

    Authors: Maria Bonou, Chris J. Kapelios, Athanasios Marinakos, Stamatis Adamopoulos, Panagiotis Diamantopoulos, Periklis G. Foukas, Loukas Kaklamanis, Penelope Korkolopoulou, John Barbetseas and Nora-Athina Viniou

    Citation: BMC Cancer 2019 19:191

    Content type: Case report

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  10. Inguinal lymph node metastasis from rectum is uncommon but well-known occurrence, whereas that from colon adenocarcinoma is extremely rare. Inguinal lymph node metastasis from colon adenocarcinoma has only bee...

    Authors: Taro Tanabe, Dai Shida, Shunsuke Tsukamoto, Goki Morizono, Hirokazu Taniguchi and Yukihide Kanemitsu

    Citation: BMC Cancer 2019 19:180

    Content type: Case report

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  11. Our objective was to identify risk factors affecting overall survival (OS) and cancer-specific survival (CSS) and build nomograms to predict survival based on a large population-based cohort.

    Authors: Chaobin He, Yu Zhang, Zhiyuan Cai and Xiaojun Lin

    Citation: BMC Cancer 2019 19:178

    Content type: Research article

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  12. Insulinoma represents hypoglycemia as a predominant symptom; the autonomic symptoms may be resolved by chronically recurrent hypoglycemia resulting in the persistence of non-specific symptoms alone. Therefore,...

    Authors: Keiichi Torimoto, Yosuke Okada, Yoshiya Tanaka, Atsuko Matsuoka, Yushi Hirota, Wataru Ogawa, Yoshifumi Saisho, Isao Kurihara, Hiroshi Itoh, Shinya Inada and Masafumi Koga

    Citation: BMC Cancer 2019 19:174

    Content type: Research article

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  13. The association between performance status (PS) and the prognosis of metastatic renal cell carcinoma (mRCC) patients receiving tyrosine kinase inhibitors (TKIs) remains controversial. The aim of this study is ...

    Authors: Yawei Xu, Yuanyuan Zhang, Xianhao Wang, Jiaqi Kang and Xiaoqiang Liu

    Citation: BMC Cancer 2019 19:168

    Content type: Research article

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  15. The patient satisfaction of symptoms improvement and disease factors that may affect long-term treatment efficacy of radiofrequency ablation (RFA) for non-functioning solid benign thyroid nodules (TNs) over a ...

    Authors: Yang Guang, Wen He, Yukun Luo, Hongxia Zhang, Yukang Zhang, Bin Ning and Tengfei Yu

    Citation: BMC Cancer 2019 19:147

    Content type: Research article

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  16. Previous related studies have mainly focused on renal cell carcinoma (RCC) with venous tumor thrombus, specifically inferior vena cava tumor thrombus with renal vein tumor thrombus (RVTT). However, only a few ...

    Authors: Chuanzhen Cao, Xingang Bi, Jing Liang, Lin Li, Huijuan Zhang, Zhendong Xiao, Zejun Xiao, Jun Tian, Dong Wang, Kaopeng Guan, Changling Li, Jianhui Ma, Shan Zheng and Jianzhong Shou

    Citation: BMC Cancer 2019 19:144

    Content type: Research article

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  17. Synovial sarcoma is a relatively rare type of soft tissue sarcoma. The commonly observed symptom is a deep-seated palpable mass accompanied by pain or tenderness. Thus, it is considered a soft tissue sarcoma a...

    Authors: Taketsugu Fujibuchi, Joji Miyawaki, Teruki Kidani, Hiroshi Imai, Hiroshi Kiyomatsu, Riko Kitazawa and Hiromasa Miura

    Citation: BMC Cancer 2019 19:116

    Content type: Case report

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  18. Post-operative pneumonia (Pop) following meningioma surgery is the dominant systemic complication which could cause serious threats to patients. It is unclear whether hematological biochemical markers are inde...

    Authors: M. R. Zuo, R. F. Liang, M. Li, Y. F. Xiang, S. X. Zhang, Y. Yang, X. Wang, Q. Mao and Y. H. Liu

    Citation: BMC Cancer 2019 19:100

    Content type: Research article

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  19. Seroma formation is the most common complication after mastectomy and places patients at risk of associated morbidities. Microporous polysaccharide hemospheres (MPH) consists of hydrophilic, plant based, polys...

    Authors: Lorena P. Suarez-Kelly, W. Hampton Pasley, Eric J. Clayton, Stephen P. Povoski, William E. Carson and Ray Rudolph

    Citation: BMC Cancer 2019 19:99

    Content type: Research article

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  20. Colorectal cancer (CRC) is the second most prevalent type of cancer in the world. Surgery is the only curative option. However, postoperative complications occur in up to 50% of patients and are associated wit...

    Authors: Stefanus van Rooijen, Francesco Carli, Susanne Dalton, Gwendolyn Thomas, Rasmus Bojesen, Morgan Le Guen, Nicolas Barizien, Rashami Awasthi, Enrico Minnella, Sandra Beijer, Graciela Martínez-Palli, Rianne van Lieshout, Ismayil Gögenur, Carlo Feo, Christoffer Johansen, Celena Scheede-Bergdahl…

    Citation: BMC Cancer 2019 19:98

    Content type: Study protocol

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  21. The decision making process for axillary dissection has changed in recent years for patients with early breast cancer and positive sentinel lymph nodes (LN). The question now arises, what is the optimal surgic...

    Authors: Florian Ebner, Achim Wöckel, Lukas Schwentner, Maria Blettner, Wolfgang Janni, Rolf Kreienberg and Manfred Wischnewsky

    Citation: BMC Cancer 2019 19:90

    Content type: Research article

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  22. With the recent introduction of novel treatment options, real-world data from patients with metastatic castration-resistant prostate cancer (mCRPC) are required to better understand the impact on routine clini...

    Authors: Martin Boegemann, Sara Khaksar, Guillaume Bera, Alison Birtle, Catherine Dopchie, Louis-Marie Dourthe, Els Everaert, Martin Hatzinger, Dirko Hercher, Werner Hilgers, Geoffrey Matus, Laura Garcia Alvarez, Laurent Antoni, Martin Lukac, Geneviève Pissart, Paul Robinson…

    Citation: BMC Cancer 2019 19:60

    Content type: Research article

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  23. The most important goal for survival benefit of advanced stage ovarian cancer is to surgically remove all visible tumour, because complete cytoreductive surgery (CCS) has been shown to be associated with prolo...

    Authors: G. M. Nieuwenhuyzen-de Boer, W. Hofhuis, N. Reesink-Peters, P. C. Ewing-Graham, I. G. Schoots, J. J. Beltman, J. M. J. Piek, A. Baalbergen, G. S. Kooi, A. van Haaften, H. van Huisseling, L. Haans, M. Dorman and H. J. van Beekhuizen

    Citation: BMC Cancer 2019 19:58

    Content type: Study protocol

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  24. Cancers of unknown primary origin (CUPs) are reported to be the 3-4th most common causes of cancer death. Recent years have seen advances in mutational analysis and genomics profiling. These advances could imp...

    Authors: Masanobu Abe, Kousuke Watanabe, Aya Shinozaki-Ushiku, Tetsuo Ushiku, Takahiro Abe, Yuko Fujihara, Yosuke Amano, Liang Zong, Cheng-Ping Wang, Emi Kubo, Ryoko Inaki, Naoya Kinoshita, Satoshi Yamashita, Daiya Takai, Toshikazu Ushijima, Takahide Nagase…

    Citation: BMC Cancer 2019 19:52

    Content type: Case report

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  25. A strong correlation between breast cancer (BC) molecular subtypes and axillary status has been shown. It would be useful to predict the probability of lymph node (LN) positivity. Objective: To develop the perfor...

    Authors: Gilles Houvenaeghel, Eric Lambaudie, Jean-Marc Classe, Chafika Mazouni, Sylvia Giard, Monique Cohen, Christelle Faure, Hélène Charitansky, Roman Rouzier, Emile Daraï, Delphine Hudry, Pierre Azuar, Richard Villet, Pierre Gimbergues, Christine Tunon de Lara, Marc Martino…

    Citation: BMC Cancer 2019 19:45

    Content type: Research article

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  26. Cystic hypersecretory carcinoma is a rare subtype of breast cancer. It is a member of cystic hypersecretory lesions, which include a series of pathological disease lineages: cystic hypersecretory hyperplasia (...

    Authors: Jie Sun, Xing Wang and Cuifang Wang

    Citation: BMC Cancer 2019 19:31

    Content type: Case report

    Published on:

  27. The eighth TNM classification for gastric cancer categorizes N3 as N3a and N3b in the final pathologic stage. The cutoff for N3a/N3b is defined as 15 metastatic lymph nodes, but the rationale for this cutoff r...

    Authors: Man-Qiang Lin, Jia-Bin Wang, Chao-Hui Zheng, Ping Li, Jian-Wei Xie, Jian-Xian Lin, Jun Lu, Qi-Yue Chen, Long-Long Cao, Mi Lin, Qing-Liang He and Chang-Ming Huang

    Citation: BMC Cancer 2019 19:21

    Content type: Research article

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  28. Salvage radiotherapy (SRT) for prostate cancer (PCa) recurrence after prostatectomy offers long-term biochemical control in about 50–60% of patients. SRT is commonly initiated in patients with serum PSA levels...

    Authors: Jeremie Calais, Johannes Czernin, Wolfgang P. Fendler, David Elashoff and Nicholas G. Nickols

    Citation: BMC Cancer 2019 19:18

    Content type: Study protocol

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    The Correction to this article has been published in BMC Cancer 2019 19:97

  29. The clinical value of total hysterectomy for patients with hydatidiform mole (HM) being at least 40 years old remains highly controversial. Since the practice of hysterectomy has been applied globally for deca...

    Authors: Peng Zhao, Yongchao Lu, Wei Huang, Baoqin Tong and Weiguo Lu

    Citation: BMC Cancer 2019 19:13

    Content type: Research article

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  30. In this retrospective study, we aimed to demonstrated that three-port single-intercostal (SIC) thoracoscopic lobectomy is an effective choice for lung cancer by comparing the perioperative outcomes of patients...

    Authors: Zixiang Wu, Qi Wang, Cong Wu, Tianwei Zhan, Lingjun Dong, Shuai Fang, Xuyang Peng, Lian Wang, Saibo Pan and Ming Wu

    Citation: BMC Cancer 2019 19:8

    Content type: Research article

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  31. The present study aims to assess the performance of 18F-FDG PET-CT on mediastinal staging of non-small cell lung cancer (NSCLC) in a location with endemic granulomatous infectious disease.

    Authors: Gustavo Werutsky, Bruno Hochhegger, José Antônio Lopes de Figueiredo Pinto, Jeovany Martínez-Mesa, Mara Lise Zanini, Eduardo Herz Berdichevski, Eduardo Vilas, Vinícius Duval da Silva, Maria Teresa Ruiz Tsukazan, Arthur Vieira, Leandro Genehr Fritscher, Louise Hartmann, Marcos Alba, Guilherme Sartori, Cristina Matushita, Vanessa Bortolotto…

    Citation: BMC Cancer 2019 19:5

    Content type: Research article

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  32. There are no published studies on the simultaneous effect of extent and location of positive surgical margins (PSMs) on biochemical recurrence (BCR) after robot-assisted laparoscopic prostatectomy (RALP). The ...

    Authors: Gautier Marcq, Aude Michelet, Gerjon Hannink, Jerome Rizk, Jean Sauvain, Arnauld Villers, Mo Saffarini and Charles H. Rochat

    Citation: BMC Cancer 2018 18:1291

    Content type: Research article

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    The Correction to this article has been published in BMC Cancer 2019 19:124

  33. Male breast cancer (MBC) is rare, accounting for only around 1% of all breast cancers. Most MBCs are hormone-driven. Not only the estrogen receptor (ER), but also other steroid hormone receptors, including the...

    Authors: Haruko Takuwa, Wakako Tsuji, Masayuki Shintaku and Fumiaki Yotsumoto

    Citation: BMC Cancer 2018 18:1282

    Content type: Case report

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  34. The neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR) are associated with poor prognoses in patients with gastric cancer; however, few studies have focused on the dynamic changes ...

    Authors: Mikito Mori, Kiyohiko Shuto, Chihiro Kosugi, Kazuo Narushima, Hideki Hayashi, Hisahiro Matsubara and Keiji Koda

    Citation: BMC Cancer 2018 18:1261

    Content type: Research article

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  35. Collision tumors are rare cases with two different tumor entities growing synchronously. While adenocarcinoma of the pancreas is the most common pancreatic tumor with an incidence of 10 per 100.000, retroperit...

    Authors: Denise Buchner, Lena Hieggelke, Heike Löser, Christiane Josephine Bruns, Alexander Quaas and Markus Philipp Hussein Ghadimi

    Citation: BMC Cancer 2018 18:1243

    Content type: Case report

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  36. More colon cancer patients are expected to fully recover after treatment due to earlier detection of cancer and improvements in general health- and cancer care. The objective of this study was to gather partic...

    Authors: C. M. den Bakker, F. G. Schaafsma, J. A. F. Huirne, E. C. J. Consten, H. B. A. C. Stockmann, C. J. Rodenburg, G. J. de Klerk, H. J. Bonjer and J. R. Anema

    Citation: BMC Cancer 2018 18:1207

    Content type: Research article

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  37. Prostate biopsy is the most common method for the diagnosis of prostate cancer and the basis for further treatment. Confirmation using radical prostatectomy specimens is the most reliable method for verifying ...

    Authors: Zhipeng Mai, Zhien Zhou, Weigang Yan, Yu Xiao, Yi Zhou, Zhiyong Liang, Zhigang Ji and Hanzhong Li

    Citation: BMC Cancer 2018 18:1205

    Content type: Research article

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  38. The incidence of colorectal cancer (CRC) is expected to increase by 80% in year 2035. Even though advantages in treatment of CRC have being made over the last decades, the outcome remains poor. Recently, sever...

    Authors: Nikoletta Dimitriou, Evangelos Felekouras, Ioannis Karavokyros, Andreas Alexandrou, Emmanuel Pikoulis and John Griniatsos

    Citation: BMC Cancer 2018 18:1202

    Content type: Research article

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  39. The aim of this study was to compare proximal fibular and proximal tibial sites regarding osteosarcoma in the proximal crus. Furthermore, we proposed a hypothesis explaining the differences.

    Authors: Hao Yao, Bo Wang, Lili Wen, Qinglin Jin, Hongbo Li, Gang Huang, Junqiang Yin, Changye Zou, Xianbiao Xie and Jingnan Shen

    Citation: BMC Cancer 2018 18:1195

    Content type: Research article

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  40. Osteosarcoma is the most common malignant bone tumor in children and young adults that produces aberrant osteoid. The aim of this study was to assess the utility of 2-deoxy-2-[18F-] fluoro-D-glucose ([18F] FDG) a...

    Authors: María Collantes, Naiara Martínez-Vélez, Marta Zalacain, Lucia Marrodán, Margarita Ecay, María José García-Velloso, Marta María Alonso, Ana Patiño-García and Iván Peñuelas

    Citation: BMC Cancer 2018 18:1193

    Content type: Research article

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  41. To investigate whether PET/CT-guided bone marrow biopsy adds complementary information for evaluation of bone marrow involvement (BMI) in newly diagnosed lymphomas.

    Authors: Bing Hao, Long Zhao, Na-na Luo, Dan Ruan, Yi-zhen Pang, Wei Guo, Hao Fu, Xiu-yu Guo, Zuo-ming Luo, Jing Wu, Hao-jun Chen, Hua Wu and Long Sun

    Citation: BMC Cancer 2018 18:1192

    Content type: Research article

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  43. Malignant bowel obstruction (MBO) is often a terminal event in end-stage cancer patients. The decision to intervene surgically is complex, given the risk of harm in patients with a limited lifespan. Therefore,...

    Authors: Sarah B. Bateni, Alicia A. Gingrich, Susan L. Stewart, Frederick J. Meyers, Richard J. Bold and Robert J. Canter

    Citation: BMC Cancer 2018 18:1166

    Content type: Research article

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  44. Supradiaphragmatic lymph node metastases (SdLNM) are frequently identified using 18F-FDG positron emission tomography/computed tomography (PET/CT) in advanced epithelial ovarian cancers (AEOC). This study aimed t...

    Authors: In Ok Lee, Jung-Yun Lee, Hyun Jeong Kim, Eun Ji Nam, Sunghoon Kim, Sang Wun Kim, Chang Young Lee, Won Jun Kang and Young Tae Kim

    Citation: BMC Cancer 2018 18:1165

    Content type: Research article

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  45. Because of the rarity of endometrioid borderline ovarian tumours (EBOTs), there is a paucity of data concerning the natural history and prognosis of this condition. Thus, the objective of our study was to esta...

    Authors: Shuang-zheng Jia, Jun-ji Zhang, Zhi-yong Liang, Jun-jun Yang, Yang Xiang, Cong-wei Jia and Jin-hua Leng

    Citation: BMC Cancer 2018 18:1160

    Content type: Research article

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  46. Three randomized trials have concluded at non inferiority of omission of complementary axillary lymph node dissection (cALND) for patients with involved sentinel node (SN). However, we can outline strong limit...

    Authors: Gilles Houvenaeghel, Monique Cohen, Pédro Raro, Jérémy De Troyer, Christine Tunon de Lara, Pierre Gimbergues, Tristan Gauthier, Christelle Faure-Virelizier, Véronique Vaini-Cowen, Stéphane Lantheaume, Claudia Regis, Emile Darai, Vivien Ceccato, Gauthier D’Halluin, Francesco Del Piano, Richard Villet…

    Citation: BMC Cancer 2018 18:1153

    Content type: Research article

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  47. Radiomics is an emerging field in oncological research. In this study, we aimed at developing a radiomics score (rad-score) to estimate postoperative recurrence and survival in patients with solitary hepatocel...

    Authors: Bo-Hao Zheng, Long-Zi Liu, Zhi-Zhi Zhang, Jie-Yi Shi, Liang-Qing Dong, Ling-Yu Tian, Zhen-bin Ding, Yuan Ji, Sheng-Xiang Rao, Jian Zhou, Jia Fan, Xiao-Ying Wang and Qiang Gao

    Citation: BMC Cancer 2018 18:1148

    Content type: Research article

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  48. Fertility sparing surgery has been extensively performed among patients with borderline ovarian tumors due to their age and favorable prognosis. Nevertheless, the prognosis and obstetric outcomes in these pati...

    Authors: Chenyan Fang, Lingqin Zhao, Xi Chen, Aijun Yu, Liang Xia and Ping Zhang

    Citation: BMC Cancer 2018 18:1147

    Content type: Research article

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  49. The lymphocyte-to-monocyte ratio (LMR) has been used as a parameter reflecting systemic inflammation in several tumors, and is reportedly associated with prognosis in cancer patients. In this study, we evaluat...

    Authors: Wataru Goto, Shinichiro Kashiwagi, Yuka Asano, Koji Takada, Katsuyuki Takahashi, Takaharu Hatano, Tsutomu Takashima, Shuhei Tomita, Hisashi Motomura, Kosei Hirakawa and Masaichi Ohira

    Citation: BMC Cancer 2018 18:1137

    Content type: Research article

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  50. Hepatocellular carcinoma (HCC) is a common cancer worldwide, with a poor prognosis. Most patients are diagnosed at advanced stages and are only eligible for palliative therapy. Therefore, this study aimed to e...

    Authors: Shiguang Chen, Wenchang Yu, Kongzhi Zhang and Weifu Liu

    Citation: BMC Cancer 2018 18:1131

    Content type: Research article

    Published on:

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