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Surgical oncology, cancer imaging, and interventional therapeutics

Section edited by Stephen P. Povoski

This section focuses on clinical research that impacts on the diagnosis and treatment of cancer using surgery, diagnostic imaging, interventional therapeutics, and surgical pathology.

Page 4 of 12

  1. Sentinel lymph node biopsy (SLNB) is standard staging procedure for nodal status in breast cancer, but lacks therapeutic benefit for patients with benign sentinel nodes. For patients with positive sentinel nod...

    Authors: Looket Dihge, Mattias Ohlsson, Patrik Edén, Pär-Ola Bendahl and Lisa Rydén

    Citation: BMC Cancer 2019 19:610

    Content type: Research article

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  2. Currently, there are three main surgical approaches for resectable esophageal cancer: open transthoracic esophagectomy (OTE), conventional minimally invasive esophagectomy (MIE) and robot-assisted esophagectom...

    Authors: Yang Yang, Xiaobin Zhang, Bin Li, Zhigang Li, Yifeng Sun, Teng Mao, Rong Hua, Yu Yang, Xufeng Guo, Yi He, Hecheng Li, Hezhong Chen and Lijie Tan

    Citation: BMC Cancer 2019 19:608

    Content type: Study protocol

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  4. Patients with hepatocellular carcinoma waiting for liver transplantation are commonly treated with locoregional treatments, such as TACE and ablation, to prevent tumor progression and dropout and to improve lo...

    Authors: Malin Sternby Eilard, Mats Andersson, Peter Naredi, Charalampos Geronymakis, Per Lindnér, Christian Cahlin, William Bennet and Magnus Rizell

    Citation: BMC Cancer 2019 19:568

    Content type: Research article

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  5. Pre-operative discrimination of malignant from benign adnexal masses is crucial for planning additional imaging, preparation, surgery and postoperative care. This study aimed to define key ultrasound and clini...

    Authors: Maciej Stukan, Michał Badocha and Karol Ratajczak

    Citation: BMC Cancer 2019 19:564

    Content type: Research article

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  6. Cabazitaxel (CBZ) chemotherapy for metastatic castration-resistant prostate cancer (mCRPC) is believed to be palliative because the radiological response rate is low and a durable response is rare. Here, we de...

    Authors: Takeo Kosaka, Hiroshi Hongo and Mototsugu Oya

    Citation: BMC Cancer 2019 19:562

    Content type: Case report

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  7. Despite recent advances in the treatments of hepatocellular carcinoma (HCC), the prognosis of HCC patients remains controversial. The purpose of this study was to investigate the prognostic performance of pret...

    Authors: Mian-Tao Wu, Su-Yin He, Shu-Lin Chen, Lin-Fang Li, Zheng-Qiang He, Yuan-Ying Zhu, Xia He and Hao Chen

    Citation: BMC Cancer 2019 19:538

    Content type: Research article

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  8. Basaloid squamous cell carcinoma of the esophagus (BSCCE) is generally detected at advanced stage and the prognosis is poorer than advanced conventional esophageal squamous cell carcinoma. Therefore, early det...

    Authors: Lianjun Di, Kuang-I Fu, Xinglong Wu, Xuemei Liu, Rui Xie, Rong Zhu and Biguang Tuo

    Citation: BMC Cancer 2019 19:513

    Content type: Case report

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  9. To investigate the long-term efficacy of the minimally invasive Ivor Lewis esophagectomy (MIILE) in esophageal squamous cell carcinoma (ESCC) patients, a retrospective comparison of the quality of life (QOL) a...

    Authors: Qi Wang, Zixiang Wu, Tianwei Zhan, Shuai Fang, Sai Zhang, Gang Shen and Ming Wu

    Citation: BMC Cancer 2019 19:500

    Content type: Research article

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  10. To determine whether magnetic resonance imaging (MRI)-detected extramural vascular invasion (mrEMVI) status is associated with quantitative perfusion parameters derived from dynamic contrast-enhanced MRI (DCE-...

    Authors: Yan Chen, Xinyue Yang, Ziqiang Wen, Yiyan Liu, Baolan Lu, Shenping Yu and Xiaojuan Xiao

    Citation: BMC Cancer 2019 19:498

    Content type: Research article

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  11. The traditional pathologic grading for human renal cell carcinoma (RCC) has low concordance between biopsy and surgical specimen. There is a need to investigate adjunctive pathology technique that does not rel...

    Authors: Sara L. Best, Yuming Liu, Adib Keikhosravi, Cole R. Drifka, Kaitlin M. Woo, Guneet S. Mehta, Marie Altwegg, Terra N. Thimm, Matthew Houlihan, Jeremy S. Bredfeldt, E. Jason Abel, Wei Huang and Kevin W. Eliceiri

    Citation: BMC Cancer 2019 19:490

    Content type: Research article

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  12. Laparoscopic-assisted pylorus-preserving gastrectomy (LAPPG) is a minimally invasive function-preserving surgery for early gastric cancer. This study was designed to investigate the clinical outcomes between L...

    Authors: Xiang Xia, Jia Xu, Chunchao Zhu, Hui Cao, Fengrong Yu and Gang Zhao

    Citation: BMC Cancer 2019 19:481

    Content type: Research article

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  15. To explore prognostic value of the pre-treatment primary lesion apparent diffusion coefficient (ADC) in locoregionally advanced nasopharyngeal carcinoma (LA-NPC).

    Authors: Tao-xiang Huang, Nian Lu, Shan-shan Lian, Hui Li, Shao-han Yin, Zhi-jun Geng and Chuan-miao Xie

    Citation: BMC Cancer 2019 19:470

    Content type: Research article

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  16. The optimal surgical margins assessment is capital in oral squamous cell carcinoma (OSCC) management. We evaluated the clinical benefits of integrating intraoperative macroscopic margin (MM) assessment and nar...

    Authors: Alessandro Baj, Nicola Fusco, Alessandro Bolzoni, Daniela Carioli, Camilla Mazzucato, Alice Faversani, Lorenzo Bresciani, Marco Maggioni and Pasquale Capaccio

    Citation: BMC Cancer 2019 19:467

    Content type: Research article

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  17. The prevalence and factors associated with major depressive disorder (MDD) among adults with cancer have been documented in the scientific literature. However, this data is limited among children and adolescen...

    Authors: Benedict Akimana, Catherine Abbo, Joyce Balagadde-Kambugu and Etheldreda Nakimuli-Mpungu

    Citation: BMC Cancer 2019 19:466

    Content type: Research article

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  18. To explore imaging biomarkers that can be used for diagnosis and prediction of pathologic stage in non-small cell lung cancer (NSCLC) using multiple machine learning algorithms based on CT image feature analysis.

    Authors: Lingming Yu, Guangyu Tao, Lei Zhu, Gang Wang, Ziming Li, Jianding Ye and Qunhui Chen

    Citation: BMC Cancer 2019 19:464

    Content type: Research article

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  19. Patients undergoing major cancer surgery frequently require post-acute care for complications and adverse effects. Enhanced recovery after surgery programmes mean that patients are increasingly discharged home...

    Authors: Kerry N. L. Avery, Hollie S. Richards, Amanda Portal, Trudy Reed, Ruth Harding, Robert Carter, Leon Bamforth, Kate Absolom, Elaine O’Connell Francischetto, Galina Velikova and Jane M. Blazeby

    Citation: BMC Cancer 2019 19:463

    Content type: Research article

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  20. Purpose of this study was to analyze whether preoperative maximum standardized uptake value (SUVmax) and carbohydrate antigen 19–9 (CA19–9) levels might provide prognostic information in Chinese patients with ...

    Authors: Xinjin Gu, Ruiquan Zhou, Chenggang Li, Rong Liu, Zhiming Zhao, Yuanxing Gao and Yong Xu

    Citation: BMC Cancer 2019 19:456

    Content type: Research article

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  21. Selection of the best lymph node for dissection is a controversial topic in clinical stage-I non-small cell lung cancer (NSCLC). Here, we sought to identify the clinicopathologic predictors of regional lymph n...

    Authors: Fei Zhao, Fu-Xi Zhen, Yue Zhou, Chen-Jun Huang, Yue Yu, Jun Li, Qi-Fan Li, Cheng-Xiang Zhu, Xiao-Yu Yang, Shu-Hui You, Qian-Ge Wu, Xue-Yun Qin, Yi Liu, Liang Chen and Wei Wang

    Citation: BMC Cancer 2019 19:444

    Content type: Research article

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  22. Colorectal cancer remains the second leading cause of cancer death in the United States, and increased risk in patients with ulcerative colitis (a subset of inflammatory bowel disease) has motivated studies in...

    Authors: Sandra P. Prieto, Cassandra L. Reed, Haley M. James, Kyle P. Quinn and Timothy J. Muldoon

    Citation: BMC Cancer 2019 19:428

    Content type: Research article

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  23. pressurized intraperitoneal aerosol chemotherapy (PIPAC), with or without electrostatic precipitation (ePIPAC), was recently introduced in the treatment of peritoneal metastases (PM) from ovarian cancer (OC). ...

    Authors: Leen Van de Sande, Wouter Willaert, Sarah Cosyns, Kaat De Clercq, Molood Shariati, Katrien Remaut and Wim Ceelen

    Citation: BMC Cancer 2019 19:424

    Content type: Technical advance

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  24. At present, palliative systemic chemotherapy is the standard treatment in the Netherlands for gastric cancer patients with peritoneal dissemination. In contrast to lymphatic and haematogenous dissemination, pe...

    Authors: W. J. Koemans, R. T. van der Kaaij, H. Boot, T. Buffart, A. A. F. A. Veenhof, K. J. Hartemink, C. Grootscholten, P. Snaebjornsson, V. P. Retel, H. van Tinteren, S. Vanhoutvin, V. van der Noort, A. Houwink, C. Hahn, A. D. R. Huitema, M. Lahaye…

    Citation: BMC Cancer 2019 19:420

    Content type: Study protocol

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  26. Postoperative chemotherapy is beneficial for many pancreatic cancer patients. However, some patients require dose reduction or the discontinuation of adjuvant chemotherapy because of adverse treatment-related ...

    Authors: Yoshifumi Morita, Takanori Sakaguchi, Ryo Kitajima, Satoru Furuhashi, Ryota Kiuchi, Makoto Takeda, Takanori Hiraide, Yasushi Shibasaki, Hirotoshi Kikuchi, Hiroyuki Konno and Hiroya Takeuchi

    Citation: BMC Cancer 2019 19:416

    Content type: Research article

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  27. Immunotherapies targeting the PD1/PD-L1 pathway have had a large impact on the treatment of advanced NSCLC. Concerning multimodality tumor therapy, only few trials until today have been performed investigating...

    Authors: Florian Eichhorn, Laura V. Klotz, Helge Bischoff, Michael Thomas, Felix Lasitschka, Hauke Winter, Hans Hoffmann and Martin E. Eichhorn

    Citation: BMC Cancer 2019 19:413

    Content type: Study protocol

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  28. To validate the robust predictive values of tumor vascularity and hand-foot-skin reaction (HFSR) in combination treatment of transarterial chemoembolization (TACE) and sorafenib for patients with intermediate ...

    Authors: Enxin Wang, Dongdong Xia, Wei Bai, Jie Yuan, Xiaomei Li, Jing Niu, Zhanxin Yin, Jielai Xia, Hongwei Cai, Daiming Fan, Guohong Han and Lei Liu

    Citation: BMC Cancer 2019 19:409

    Content type: Research article

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  29. Preoperative chemoradiotherapy (pre-CRT) followed by total mesorectal excision (TME) is currently a standard therapy for locally advanced mid-to-low rectal cancer. Less aggressive, organ-preserving option such...

    Authors: Jong Lyul Lee, Seok-Byung Lim, Chang Sik Yu, In Ja Park, Yong Sik Yoon, Chan Wook Kim, Seong Ho Park, Jong Seok Lee, Yong Sang Hong, Sun Young Kim, Jeong Eun Kim, Jong Hoon Kim, Jin-hong Park, Jihun Kim and Minkyu Han

    Citation: BMC Cancer 2019 19:404

    Content type: Study protocol

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  30. Locally advanced pancreatic cancer (LAPC) represents more than one third of pancreatic cancers and owns poor survival after the standard chemotherapy. Irreversible electroporation (IRE) is a novel method and h...

    Authors: Chaobin He, Jun Wang, Shuxin Sun, Yu Zhang, Xiaojun Lin, Xiangming Lao, Bokang Cui and Shengping Li

    Citation: BMC Cancer 2019 19:394

    Content type: Research article

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  31. Upfront cytoreductive surgery with HIPEC (CRS-HIPEC) is the standard treatment for isolated resectable colorectal peritoneal metastases (PM) in the Netherlands. This study investigates whether addition of peri...

    Authors: Koen P. Rovers, Checca Bakkers, Geert A. A. M. Simkens, Jacobus W. A. Burger, Simon W. Nienhuijs, Geert-Jan M. Creemers, Anna M. J. Thijs, Alexandra R. M. Brandt-Kerkhof, Eva V. E. Madsen, Ninos Ayez, Nadine L. de Boer, Esther van Meerten, Jurriaan B. Tuynman, Miranda Kusters, Nina R. Sluiter, Henk M. W. Verheul…

    Citation: BMC Cancer 2019 19:390

    Content type: Study protocol

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  33. Most endocervical adenocarcinomas are human papillomavirus (HPV)-related cancers associated with p16 immunostaining. Ovarian metastasis from cervical cancer is a rare phenomenon, the mechanism of dissemination...

    Authors: Alexandra Arfi, Delphine Hequet, Guillaume Bataillon, Carine Tran-Perennou, Fereshteh Farkhondeh, Xavier Sastre-Garau, Virginie Fourchotte, Roman Rouzier, Enora Laas, Nicolas Pouget, Anne Vincent-Salomon and Emmanuelle Jeannot

    Citation: BMC Cancer 2019 19:375

    Content type: Case report

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  35. As the efficacy of radiotherapy and chemotherapy for treatment of phyllodes tumors (PTs) remains unclear, this study aimed to review all available data and evaluate the roles of radiotherapy and chemotherapy i...

    Authors: Xue Chao, Kai Chen, Jiayi Zeng, Zhuofei Bi, Mingyan Guo, Yi Chen, Yandan Yao, Wei Wu, Shi Liang and Yan Nie

    Citation: BMC Cancer 2019 19:372

    Content type: Research article

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  36. Our aim of the study is to investigate the feasibility of preoperative prediction for hepatocellular carcinoma (HCC) histological grading using gadoxetic acid-enhanced magnetic resonance imaging (MRI).

    Authors: Kun Huang, Zhi Dong, Huasong Cai, Mengqi Huang, Zhenpeng Peng, Ling Xu, Yingmei Jia, Chenyu Song, Zi-Ping Li and Shi-Ting Feng

    Citation: BMC Cancer 2019 19:364

    Content type: Research article

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  37. Hematopoietic stem cell transplantation (HSCT) remains an important therapeutic option for many hematologic malignancies. Bone marrow harvesting from an appropriate donor must be conducted for hematopoietic st...

    Authors: Tae-Woo Nam, Hyun-Min Oh, Jae-Eun Lee, Ju-Hyun Kim, Jong-moon Hwang, Eunhee Park and Tae-Du Jung

    Citation: BMC Cancer 2019 19:347

    Content type: Case report

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  38. Background: Benign breast lesions are the most common diseases in adult women, which have been treated with minimally invasive therapies in recent years. Little is known about the feasibility of Microwave abla...

    Authors: Wei Zhang, Zhan-Qiang Jin, Masoud Baikpour, Jian-Min Li, Hui Zhang, Ting Liang, Xiao-Ming Pan and Wen He

    Citation: BMC Cancer 2019 19:345

    Content type: Research article

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  39. Outcomes of patients with ovarian high-grade serous carcinoma (HGSC) treated with neoadjuvant chemotherapy (NAC) have been widely studied, but there is limited information on the outcomes of patients with non-...

    Authors: Young Shin Chung, Sang-Yoon Park, Jung-Yun Lee, Jeong-Yeol Park, Jeong-Won Lee, Hee Seung Kim, Dong Soo Suh, Yun Hwan Kim, Jong-Min Lee, Miseon Kim, Min Chul Choi, Seung-Hyuk Shim, Keun Ho Lee, Taejong Song, Jin Hwa Hong, Won Moo Lee…

    Citation: BMC Cancer 2019 19:341

    Content type: Research article

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  40. Here we describe the treatments and prognosis for metachronous metastases from gastroenteropancreatic neuroendocrine tumors (GEP-NETs) after initial R0 surgical resection at a large center in China.

    Authors: Yang Lv, Xu Han, Xue-Feng Xu, Yuan Ji, Yu-Hong Zhou, Hui-Chuan Sun, Jian Zhou, Jia Fan, Wen-Hui Lou and Cheng Huang

    Citation: BMC Cancer 2019 19:335

    Content type: Research article

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  41. Recurrences are reported in 70% of all patients after resection of colorectal liver metastases (CRLM), in which half are confined to the liver. Adjuvant hepatic arterial infusion pump (HAIP) chemotherapy aims ...

    Authors: F. E. Buisman, M. Y. V. Homs, D. J. Grünhagen, W. F. Filipe, R. J. Bennink, M. G. H. Besselink, I. H. M. Borel Rinkes, R. C. G. Bruijnen, A. Cercek, M. I. D’Angelica, O. M. van Delden, M. L. Donswijk, L. van Doorn, P. G. Doornebosch, J. Emmering, J. I. Erdmann…

    Citation: BMC Cancer 2019 19:327

    Content type: Study protocol

    Published on:

  42. We are reporting a rare case of MUTYH-associated polyposis, a colorectal cancer hereditary syndrome, diagnosticated after an intussusception. Colorectal cancer is an important cause of cancer related mortality...

    Authors: Gustavo Heluani Antunes de Mesquita, Bárbara Justo Carvalho, Kayo Augusto de Almeida Medeiros, Fernanda Nii, Diego Ramos Martines, Leonardo Zumerkorn Pipek, Yuri Justi Jardim, Daniel Reis Waisberg, Marcos Takeo Obara, Roberta Sitnik, Alberto Meyer and Cristóvão Luis Pitangueiras Mangueira

    Citation: BMC Cancer 2019 19:324

    Content type: Case report

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  43. Multiple trials have attempted to assess the diagnostic value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) in osteosarcoma with results remaining inconclusive. This ...

    Authors: Fanxiao Liu, Qingyu Zhang, Dongsheng Zhou and Jinlei Dong

    Citation: BMC Cancer 2019 19:323

    Content type: Research article

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  44. Oesophageal cancer has a high metastatic potential and poor prognosis, with a significant risk of recurrence after radical resection. However, resected pancreatic metastasis from oesophageal cancer is rare.

    Authors: Wataru Koizumi, Minoru Kitago, Masahiro Shinoda, Hiroshi Yagi, Yuta Abe, Go Oshima, Shutaro Hori, Kenta Inomata, Hirofumi Kawakubo, Miho Kawaida and Yuko Kitagawa

    Citation: BMC Cancer 2019 19:320

    Content type: Case report

    Published on:

  45. To evaluate the diagnostic value of MR imaging for the differentiation of lipomas and atypical lipomatous tumors (ALT) in comparison with histology and MDM2 amplification status.

    Authors: Carolin Knebel, Jan Neumann, Benedikt J. Schwaiger, Dimitris C. Karampinos, Daniela Pfeiffer, Katja Specht, Ulrich Lenze, Rüdiger von Eisenhart-Rothe, Ernst J. Rummeny, Klaus Woertler and Alexandra S. Gersing

    Citation: BMC Cancer 2019 19:309

    Content type: Research article

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  46. Many factors influence bone metastases of lung cancer, and several studies report about survival of skeletal metastasis. However, few studies have focused on identifying the prognostic factors for skeletal met...

    Authors: Yong Jin Cho, Yung Min Cho, Sung Hyun Kim, Kyoo-Ho Shin, Sung-Taek Jung and Hyo Song Kim

    Citation: BMC Cancer 2019 19:303

    Content type: Research article

    Published on:

  47. We reported previously the usefulness of 18F-2-fluoro-2-deoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) to predict prognosis of renal cell carcinoma (RCC) treated with molecular targ...

    Authors: Tadashi Tabei, Noboru Nakaigawa, Tomohiro Kaneta, Ichiro Ikeda, Keiichi Kondo, Kazuhide Makiyama, Hisashi Hasumi, Narihiko Hayashi, Takashi Kawahara, Koji Izumi, Kimito Osaka, Kentaro Muraoka, Jun-ichi Teranishi, Yasuhide Miyoshi, Yasushi Yumura, Hiroji Uemura…

    Citation: BMC Cancer 2019 19:298

    Content type: Research article

    Published on:

  48. Early gastric cancer is associated with a much better prognosis than advanced disease, and strategies to improve prognosis is strictly dependent on earlier detection and accurate diagnosis. Therefore, a label-...

    Authors: Lianhuang Li, Deyong Kang, Zicheng Huang, Zhenlin Zhan, Changyin Feng, Yongjian Zhou, Haohua Tu, Shuangmu Zhuo and Jianxin Chen

    Citation: BMC Cancer 2019 19:295

    Content type: Research article

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  49. Approximately 20–30% of patients with pT4 colon cancer develop metachronous peritoneal metastases (PM). Due to restricted accuracy of imaging modalities and absence of early symptoms, PM are often detected at ...

    Authors: Vivian P. Bastiaenen, Charlotte E. L. Klaver, Niels F. M. Kok, Johannes H. W. de Wilt, Ignace H. J. T. de Hingh, Arend G. J. Aalbers, Djamila Boerma, Andre J. A. Bremers, Jacobus W. A. Burger, Eino B. van Duyn, Pauline Evers, Wilhelmina M. U. van Grevenstein, Patrick H. J. Hemmer, Eva V. E. Madsen, Petur Snaebjornsson, Jurriaan B. Tuynman…

    Citation: BMC Cancer 2019 19:254

    Content type: Study protocol

    Published on:

  50. Carbohydrate antigen (CA) 19–9 levels after resection are considered to predict prognosis; however, the significance of decreased CA19–9 levels after neoadjuvant therapy has not been clarified. This study aime...

    Authors: Shuichi Aoki, Fuyuhiko Motoi, Yoshiaki Murakami, Masayuki Sho, Sohei Satoi, Goro Honda, Kenichiro Uemura, Ken-ichi Okada, Ippei Matsumoto, Minako Nagai, Hiroaki Yanagimoto, Masanao Kurata, Takumi Fukumoto, Masamichi Mizuma, Hiroki Yamaue and Michiaki Unno

    Citation: BMC Cancer 2019 19:252

    Content type: Research article

    Published on:

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