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Surgical oncology, cancer imaging, and interventional therapeutics

Section edited by Stephen P. Povoski

This section focuses on clinical research that impacts on the diagnosis and treatment of cancer using surgery, diagnostic imaging, interventional therapeutics, and surgical pathology.

Page 3 of 10

  1. Content type: Research article

    Post-operative pneumonia (Pop) following meningioma surgery is the dominant systemic complication which could cause serious threats to patients. It is unclear whether hematological biochemical markers are inde...

    Authors: M. R. Zuo, R. F. Liang, M. Li, Y. F. Xiang, S. X. Zhang, Y. Yang, X. Wang, Q. Mao and Y. H. Liu

    Citation: BMC Cancer 2019 19:100

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  2. Content type: Study protocol

    Colorectal cancer (CRC) is the second most prevalent type of cancer in the world. Surgery is the only curative option. However, postoperative complications occur in up to 50% of patients and are associated wit...

    Authors: Stefanus van Rooijen, Francesco Carli, Susanne Dalton, Gwendolyn Thomas, Rasmus Bojesen, Morgan Le Guen, Nicolas Barizien, Rashami Awasthi, Enrico Minnella, Sandra Beijer, Graciela Martínez-Palli, Rianne van Lieshout, Ismayil Gögenur, Carlo Feo, Christoffer Johansen, Celena Scheede-Bergdahl…

    Citation: BMC Cancer 2019 19:98

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  3. Content type: Research article

    The decision making process for axillary dissection has changed in recent years for patients with early breast cancer and positive sentinel lymph nodes (LN). The question now arises, what is the optimal surgic...

    Authors: Florian Ebner, Achim Wöckel, Lukas Schwentner, Maria Blettner, Wolfgang Janni, Rolf Kreienberg and Manfred Wischnewsky

    Citation: BMC Cancer 2019 19:90

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  4. Content type: Research article

    With the recent introduction of novel treatment options, real-world data from patients with metastatic castration-resistant prostate cancer (mCRPC) are required to better understand the impact on routine clini...

    Authors: Martin Boegemann, Sara Khaksar, Guillaume Bera, Alison Birtle, Catherine Dopchie, Louis-Marie Dourthe, Els Everaert, Martin Hatzinger, Dirko Hercher, Werner Hilgers, Geoffrey Matus, Laura Garcia Alvarez, Laurent Antoni, Martin Lukac, Geneviève Pissart, Paul Robinson…

    Citation: BMC Cancer 2019 19:60

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  5. Content type: Study protocol

    The most important goal for survival benefit of advanced stage ovarian cancer is to surgically remove all visible tumour, because complete cytoreductive surgery (CCS) has been shown to be associated with prolo...

    Authors: G. M. Nieuwenhuyzen-de Boer, W. Hofhuis, N. Reesink-Peters, P. C. Ewing-Graham, I. G. Schoots, J. J. Beltman, J. M. J. Piek, A. Baalbergen, G. S. Kooi, A. van Haaften, H. van Huisseling, L. Haans, M. Dorman and H. J. van Beekhuizen

    Citation: BMC Cancer 2019 19:58

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  6. Content type: Case report

    Cancers of unknown primary origin (CUPs) are reported to be the 3-4th most common causes of cancer death. Recent years have seen advances in mutational analysis and genomics profiling. These advances could imp...

    Authors: Masanobu Abe, Kousuke Watanabe, Aya Shinozaki-Ushiku, Tetsuo Ushiku, Takahiro Abe, Yuko Fujihara, Yosuke Amano, Liang Zong, Cheng-Ping Wang, Emi Kubo, Ryoko Inaki, Naoya Kinoshita, Satoshi Yamashita, Daiya Takai, Toshikazu Ushijima, Takahide Nagase…

    Citation: BMC Cancer 2019 19:52

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  7. Content type: Research article

    A strong correlation between breast cancer (BC) molecular subtypes and axillary status has been shown. It would be useful to predict the probability of lymph node (LN) positivity. Objective: To develop the perfor...

    Authors: Gilles Houvenaeghel, Eric Lambaudie, Jean-Marc Classe, Chafika Mazouni, Sylvia Giard, Monique Cohen, Christelle Faure, Hélène Charitansky, Roman Rouzier, Emile Daraï, Delphine Hudry, Pierre Azuar, Richard Villet, Pierre Gimbergues, Christine Tunon de Lara, Marc Martino…

    Citation: BMC Cancer 2019 19:45

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  8. Content type: Case report

    Cystic hypersecretory carcinoma is a rare subtype of breast cancer. It is a member of cystic hypersecretory lesions, which include a series of pathological disease lineages: cystic hypersecretory hyperplasia (...

    Authors: Jie Sun, Xing Wang and Cuifang Wang

    Citation: BMC Cancer 2019 19:31

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  9. Content type: Research article

    The eighth TNM classification for gastric cancer categorizes N3 as N3a and N3b in the final pathologic stage. The cutoff for N3a/N3b is defined as 15 metastatic lymph nodes, but the rationale for this cutoff r...

    Authors: Man-Qiang Lin, Jia-Bin Wang, Chao-Hui Zheng, Ping Li, Jian-Wei Xie, Jian-Xian Lin, Jun Lu, Qi-Yue Chen, Long-Long Cao, Mi Lin, Qing-Liang He and Chang-Ming Huang

    Citation: BMC Cancer 2019 19:21

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  10. Content type: Study protocol

    Salvage radiotherapy (SRT) for prostate cancer (PCa) recurrence after prostatectomy offers long-term biochemical control in about 50–60% of patients. SRT is commonly initiated in patients with serum PSA levels...

    Authors: Jeremie Calais, Johannes Czernin, Wolfgang P. Fendler, David Elashoff and Nicholas G. Nickols

    Citation: BMC Cancer 2019 19:18

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    The Correction to this article has been published in BMC Cancer 2019 19:97

  11. Content type: Research article

    The clinical value of total hysterectomy for patients with hydatidiform mole (HM) being at least 40 years old remains highly controversial. Since the practice of hysterectomy has been applied globally for deca...

    Authors: Peng Zhao, Yongchao Lu, Wei Huang, Baoqin Tong and Weiguo Lu

    Citation: BMC Cancer 2019 19:13

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  12. Content type: Research article

    In this retrospective study, we aimed to demonstrated that three-port single-intercostal (SIC) thoracoscopic lobectomy is an effective choice for lung cancer by comparing the perioperative outcomes of patients...

    Authors: Zixiang Wu, Qi Wang, Cong Wu, Tianwei Zhan, Lingjun Dong, Shuai Fang, Xuyang Peng, Lian Wang, Saibo Pan and Ming Wu

    Citation: BMC Cancer 2019 19:8

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  13. Content type: Research article

    The present study aims to assess the performance of 18F-FDG PET-CT on mediastinal staging of non-small cell lung cancer (NSCLC) in a location with endemic granulomatous infectious disease.

    Authors: Gustavo Werutsky, Bruno Hochhegger, José Antônio Lopes de Figueiredo Pinto, Jeovany Martínez-Mesa, Mara Lise Zanini, Eduardo Herz Berdichevski, Eduardo Vilas, Vinícius Duval da Silva, Maria Teresa Ruiz Tsukazan, Arthur Vieira, Leandro Genehr Fritscher, Louise Hartmann, Marcos Alba, Guilherme Sartori, Cristina Matushita, Vanessa Bortolotto…

    Citation: BMC Cancer 2019 19:5

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  14. Content type: Research article

    There are no published studies on the simultaneous effect of extent and location of positive surgical margins (PSMs) on biochemical recurrence (BCR) after robot-assisted laparoscopic prostatectomy (RALP). The ...

    Authors: Gautier Marcq, Aude Michelet, Gerjon Hannink, Jerome Rizk, Jean Sauvain, Arnauld Villers, Mo Saffarini and Charles H. Rochat

    Citation: BMC Cancer 2018 18:1291

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    The Correction to this article has been published in BMC Cancer 2019 19:124

  15. Content type: Case report

    Male breast cancer (MBC) is rare, accounting for only around 1% of all breast cancers. Most MBCs are hormone-driven. Not only the estrogen receptor (ER), but also other steroid hormone receptors, including the...

    Authors: Haruko Takuwa, Wakako Tsuji, Masayuki Shintaku and Fumiaki Yotsumoto

    Citation: BMC Cancer 2018 18:1282

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  16. Content type: Research article

    The neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR) are associated with poor prognoses in patients with gastric cancer; however, few studies have focused on the dynamic changes ...

    Authors: Mikito Mori, Kiyohiko Shuto, Chihiro Kosugi, Kazuo Narushima, Hideki Hayashi, Hisahiro Matsubara and Keiji Koda

    Citation: BMC Cancer 2018 18:1261

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  17. Content type: Case report

    Collision tumors are rare cases with two different tumor entities growing synchronously. While adenocarcinoma of the pancreas is the most common pancreatic tumor with an incidence of 10 per 100.000, retroperit...

    Authors: Denise Buchner, Lena Hieggelke, Heike Löser, Christiane Josephine Bruns, Alexander Quaas and Markus Philipp Hussein Ghadimi

    Citation: BMC Cancer 2018 18:1243

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  18. Content type: Research article

    More colon cancer patients are expected to fully recover after treatment due to earlier detection of cancer and improvements in general health- and cancer care. The objective of this study was to gather partic...

    Authors: C. M. den Bakker, F. G. Schaafsma, J. A. F. Huirne, E. C. J. Consten, H. B. A. C. Stockmann, C. J. Rodenburg, G. J. de Klerk, H. J. Bonjer and J. R. Anema

    Citation: BMC Cancer 2018 18:1207

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  19. Content type: Research article

    Prostate biopsy is the most common method for the diagnosis of prostate cancer and the basis for further treatment. Confirmation using radical prostatectomy specimens is the most reliable method for verifying ...

    Authors: Zhipeng Mai, Zhien Zhou, Weigang Yan, Yu Xiao, Yi Zhou, Zhiyong Liang, Zhigang Ji and Hanzhong Li

    Citation: BMC Cancer 2018 18:1205

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  20. Content type: Research article

    The incidence of colorectal cancer (CRC) is expected to increase by 80% in year 2035. Even though advantages in treatment of CRC have being made over the last decades, the outcome remains poor. Recently, sever...

    Authors: Nikoletta Dimitriou, Evangelos Felekouras, Ioannis Karavokyros, Andreas Alexandrou, Emmanuel Pikoulis and John Griniatsos

    Citation: BMC Cancer 2018 18:1202

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  21. Content type: Research article

    The aim of this study was to compare proximal fibular and proximal tibial sites regarding osteosarcoma in the proximal crus. Furthermore, we proposed a hypothesis explaining the differences.

    Authors: Hao Yao, Bo Wang, Lili Wen, Qinglin Jin, Hongbo Li, Gang Huang, Junqiang Yin, Changye Zou, Xianbiao Xie and Jingnan Shen

    Citation: BMC Cancer 2018 18:1195

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  22. Content type: Research article

    Osteosarcoma is the most common malignant bone tumor in children and young adults that produces aberrant osteoid. The aim of this study was to assess the utility of 2-deoxy-2-[18F-] fluoro-D-glucose ([18F] FDG) a...

    Authors: María Collantes, Naiara Martínez-Vélez, Marta Zalacain, Lucia Marrodán, Margarita Ecay, María José García-Velloso, Marta María Alonso, Ana Patiño-García and Iván Peñuelas

    Citation: BMC Cancer 2018 18:1193

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  23. Content type: Research article

    To investigate whether PET/CT-guided bone marrow biopsy adds complementary information for evaluation of bone marrow involvement (BMI) in newly diagnosed lymphomas.

    Authors: Bing Hao, Long Zhao, Na-na Luo, Dan Ruan, Yi-zhen Pang, Wei Guo, Hao Fu, Xiu-yu Guo, Zuo-ming Luo, Jing Wu, Hao-jun Chen, Hua Wu and Long Sun

    Citation: BMC Cancer 2018 18:1192

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  24. Content type: Research article

    Malignant bowel obstruction (MBO) is often a terminal event in end-stage cancer patients. The decision to intervene surgically is complex, given the risk of harm in patients with a limited lifespan. Therefore,...

    Authors: Sarah B. Bateni, Alicia A. Gingrich, Susan L. Stewart, Frederick J. Meyers, Richard J. Bold and Robert J. Canter

    Citation: BMC Cancer 2018 18:1166

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  25. Content type: Research article

    Supradiaphragmatic lymph node metastases (SdLNM) are frequently identified using 18F-FDG positron emission tomography/computed tomography (PET/CT) in advanced epithelial ovarian cancers (AEOC). This study aimed t...

    Authors: In Ok Lee, Jung-Yun Lee, Hyun Jeong Kim, Eun Ji Nam, Sunghoon Kim, Sang Wun Kim, Chang Young Lee, Won Jun Kang and Young Tae Kim

    Citation: BMC Cancer 2018 18:1165

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  26. Content type: Research article

    Because of the rarity of endometrioid borderline ovarian tumours (EBOTs), there is a paucity of data concerning the natural history and prognosis of this condition. Thus, the objective of our study was to esta...

    Authors: Shuang-zheng Jia, Jun-ji Zhang, Zhi-yong Liang, Jun-jun Yang, Yang Xiang, Cong-wei Jia and Jin-hua Leng

    Citation: BMC Cancer 2018 18:1160

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  27. Content type: Research article

    Three randomized trials have concluded at non inferiority of omission of complementary axillary lymph node dissection (cALND) for patients with involved sentinel node (SN). However, we can outline strong limit...

    Authors: Gilles Houvenaeghel, Monique Cohen, Pédro Raro, Jérémy De Troyer, Christine Tunon de Lara, Pierre Gimbergues, Tristan Gauthier, Christelle Faure-Virelizier, Véronique Vaini-Cowen, Stéphane Lantheaume, Claudia Regis, Emile Darai, Vivien Ceccato, Gauthier D’Halluin, Francesco Del Piano, Richard Villet…

    Citation: BMC Cancer 2018 18:1153

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  28. Content type: Research article

    Radiomics is an emerging field in oncological research. In this study, we aimed at developing a radiomics score (rad-score) to estimate postoperative recurrence and survival in patients with solitary hepatocel...

    Authors: Bo-Hao Zheng, Long-Zi Liu, Zhi-Zhi Zhang, Jie-Yi Shi, Liang-Qing Dong, Ling-Yu Tian, Zhen-bin Ding, Yuan Ji, Sheng-Xiang Rao, Jian Zhou, Jia Fan, Xiao-Ying Wang and Qiang Gao

    Citation: BMC Cancer 2018 18:1148

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  29. Content type: Research article

    Fertility sparing surgery has been extensively performed among patients with borderline ovarian tumors due to their age and favorable prognosis. Nevertheless, the prognosis and obstetric outcomes in these pati...

    Authors: Chenyan Fang, Lingqin Zhao, Xi Chen, Aijun Yu, Liang Xia and Ping Zhang

    Citation: BMC Cancer 2018 18:1147

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  30. Content type: Research article

    The lymphocyte-to-monocyte ratio (LMR) has been used as a parameter reflecting systemic inflammation in several tumors, and is reportedly associated with prognosis in cancer patients. In this study, we evaluat...

    Authors: Wataru Goto, Shinichiro Kashiwagi, Yuka Asano, Koji Takada, Katsuyuki Takahashi, Takaharu Hatano, Tsutomu Takashima, Shuhei Tomita, Hisashi Motomura, Kosei Hirakawa and Masaichi Ohira

    Citation: BMC Cancer 2018 18:1137

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  31. Content type: Research article

    Hepatocellular carcinoma (HCC) is a common cancer worldwide, with a poor prognosis. Most patients are diagnosed at advanced stages and are only eligible for palliative therapy. Therefore, this study aimed to e...

    Authors: Shiguang Chen, Wenchang Yu, Kongzhi Zhang and Weifu Liu

    Citation: BMC Cancer 2018 18:1131

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  32. Content type: Study protocol

    Gastric cancer is one of the most common malignant tumors worldwide. With the rapid aging of global population, the number of elderly patients with local advanced gastric cancer is increasing. Surgery is the e...

    Authors: Ziyu Li, Fei Shan, Xiangji Ying, Kan Xue and Jiafu Ji

    Citation: BMC Cancer 2018 18:1118

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  33. Content type: Research article

    With advances in gastric cancer chemotherapy, conversion surgery has drawn attention as a new strategy to improve the outcome of stage IV disease. We investigated the efficacy of conversion surgery following c...

    Authors: Seung-Hoon Beom, Yoon Young Choi, Song-Ee Baek, Shuang-Xi Li, Joon Seok Lim, Taeil Son, Hyoung-Il Kim, Jae-Ho Cheong, Woo Jin Hyung, Seung Ho Choi, Minkyu Jung, Hyo Song Kim, Hei-Cheul Jeung, Hyun Cheol Chung, Sun Young Rha and Sung Hoon Noh

    Citation: BMC Cancer 2018 18:1116

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  34. Content type: Case report

    Sacral chordoma is a locally aggressive malignant tumour originating from ectopic notochordal cells. The natural history of sacral chordoma is a slow growing tumour arising at the midline of the lower sacrum t...

    Authors: Zi Hao Phang, Xue Yi Saw, Noreen Fadzlina Binti Mat Nor, Zolqarnain Bin Ahmad and Sa’adon Bin Ibrahim

    Citation: BMC Cancer 2018 18:1112

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  35. Content type: Research article

    In a previous study utilizing mass spectrometry-based proteomics, we identified calcium-activated chloride channel regulator 1 (CLCA1) as a potential tumor suppressor in pancreatic cancer and the expression wa...

    Authors: Dingyuan Hu, Daniel Ansari, Qimin Zhou, Agata Sasor, Katarzyna Said Hilmersson, Monika Bauden, Yi Jiang and Roland Andersson

    Citation: BMC Cancer 2018 18:1096

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  36. Content type: Research article

    This study aims to establish a radiomics analysis system for the diagnosis and clinical behaviour prediction of hepatocellular carcinoma (HCC) based on multi-parametric ultrasound imaging.

    Authors: Zhao Yao, Yi Dong, Guoqing Wu, Qi Zhang, Daohui Yang, Jin-Hua Yu and Wen-Ping Wang

    Citation: BMC Cancer 2018 18:1089

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  37. Content type: Research article

    The objective of our study was to evaluate the clinical significance of invisible prostate cancer (iPCa) on multiparametric magnetic resonance imaging (mpMRI) by analyzing clinical parameters and oncologic out...

    Authors: Doo Yong Chung, Dong Hoon Koh, Hyeok Jun Goh, Min Seok Kim, Jong Soo Lee, Won Sik Jang and Young Deuk Choi

    Citation: BMC Cancer 2018 18:1057

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  38. Content type: Research article

    Psychiatric patients with colorectal cancer may have delayed diagnosis and be oncologically undertreated.

    Authors: Linda Kaerlev, Maria Iachina, Oleg Trosko, Niels Qvist, Pernille Møller Ljungdalh and Bente Mertz Nørgård

    Citation: BMC Cancer 2018 18:1050

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  39. Content type: Research article

    The oncologic safety of allogeneic blood transfusion in ovarian cancer patients is unknow. We sought to determine the prevalence and oncologic safety of perioperative allogeneic blood transfusion during interv...

    Authors: Kevin W McCool, Emmanuel Sampene, Brock Polnaszek, Joseph Connor, Erin E Medlin and Lisa Barroilhet

    Citation: BMC Cancer 2018 18:1041

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  40. Content type: Case report

    Difficult resection of tumors from regions with complex local anatomy, such as the pelvis and sacrum, is likely to result in inadequate surgical margins (intralesional or marginal); this is because three-dimen...

    Authors: Kensaku Abe, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Hiroyuki Inatani, Yu Aoki, Takashi Higuchi, Yuta Taniguchi, Hirotaka Yonezawa, Yoshihiro Araki and Hiroyuki Tsuchiya

    Citation: BMC Cancer 2018 18:1036

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  41. Content type: Research article

    Pancreatic cancer is a highly malignant tumor with a poor prognosis. Chemotherapy such as gemcitabine is still an important treatment. Gemcitabine (Gem) may prolong survival time and delay the development of r...

    Authors: Hua Chen, Ruizhi He, Xiuhui Shi, Min Zhou, Chunle Zhao, Hang Zhang and Renyi Qin

    Citation: BMC Cancer 2018 18:1034

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  42. Content type: Research article

    Cavity occurs in 5.7 to 14.9% of patients with lung adenocarcinoma (ADC). However, the impact of cavity on the therapeutic response to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) in...

    Authors: Fei Zhou, Wanrong Ma, Wei Li, Huijuan Ni, Guanghui Gao, Xiaoxia Chen, Jie Zhang and Jingyun Shi

    Citation: BMC Cancer 2018 18:1033

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  43. Content type: Research article

    To assess the prognostic factors and investigate the optimal treatment of gastric mixed adenoneuroendocrine tumors.

    Authors: Jian-Wei Xie, Jun Lu, Jia-Bin Wang, Jian-Xian Lin, Qi-Yue Chen, Long-Long Cao, Mi Lin, Ru-Hong Tu, Ze-Ning Huang, Ju-Li Lin, Chao-Hui Zheng, Ping Li and Chang-Ming Huang

    Citation: BMC Cancer 2018 18:1021

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  44. Content type: Research article

    Peripheral monocyte count is an assessable parameter. Recently, evidence suggested an elevated preoperative monocyte counts predicting poor prognosis in malignancies. The aim of this study was to determine the...

    Authors: Yang Hai, Nan Chen, Wenwen Wu, Zihuai Wang, Feng Lin, Chenglin Guo, Chengwu Liu, Weimin Li and Lunxu Liu

    Citation: BMC Cancer 2018 18:1011

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  45. Content type: Study protocol

    Nearly one third of patients undergoing neoadjuvant chemoradiotherapy (nCRT) for locally advanced esophageal cancer have a pathologic complete response (pCR) of the primary tumor upon histopathological evaluat...

    Authors: A. S. Borggreve, S. Mook, M. Verheij, V. E. M. Mul, J. J. Bergman, A. Bartels-Rutten, L. C. ter Beek, R. G. H. Beets-Tan, R. J. Bennink, M. I. van Berge Henegouwen, L. A. A. Brosens, I. L. Defize, J. M. van Dieren, H. Dijkstra, R. van Hillegersberg, M. C. Hulshof…

    Citation: BMC Cancer 2018 18:1006

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  46. Content type: Case report

    The incidence of ocular metastasis from lung cancer is reported to be 0.1–7%, with adenocarcinoma and small cell lung cancer accounting for the highest proportions of these cases. The majority of cases involve...

    Authors: Ye Guo, Xu Wang, Jun Xiao, Yinghui Xu, Yangyang Cai, Chao Sun and Kewei Ma

    Citation: BMC Cancer 2018 18:1004

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  47. Content type: Case report

    Sarcomas that arise from the scapula or periscapular soft tissues often require a total scapulectomy. This often implies a large complex tissue defect that needs adequate reconstruction of both bone and soft t...

    Authors: Giovanni Beltrami, Gabriele Ristori, Guido Scoccianti, Angela Tamburini, Rodolfo Capanna, Domenico Campanacci and Marco Innocenti

    Citation: BMC Cancer 2018 18:1003

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  48. Content type: Research article

    The evaluation of cervical lymph nodes is very important for patients with papillary thyroid carcinoma (PTC). Conventional ultrasound is recommended to assess the status of cervical lymph nodes but the diagnos...

    Authors: Wanying Chang, Lei Tang, Caiwei Lu, Min Wu and Man Chen

    Citation: BMC Cancer 2018 18:1001

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