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Surgical oncology, cancer imaging, and interventional therapeutics

Section edited by Stephen P. Povoski

This section focuses on clinical research that impacts on the diagnosis and treatment of cancer using surgery, diagnostic imaging, interventional therapeutics, and surgical pathology.

Page 3 of 14

  1. There is no comprehensive agreement concerning the overall performance of radical resection for T1b gallbladder cancer (GBC). This research focused on addressing whether T1b GBC may spread loco-regionally and ...

    Authors: Kizuki Yuza, Jun Sakata, Pankaj Prasoon, Yuki Hirose, Taku Ohashi, Koji Toge, Kohei Miura, Masayuki Nagahashi, Takashi Kobayashi and Toshifumi Wakai

    Citation: BMC Cancer 2020 20:20

    Content type: Research article

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  2. Adjuvant chemotherapy is relatively underused in older patients with colon cancer in Japan, and its age-specific effects on clinical outcomes remain unclear. This study aimed to assess the effect of adjuvant c...

    Authors: Hidetaka Kawamura, Toshitaka Morishima, Akira Sato, Michitaka Honda and Isao Miyashiro

    Citation: BMC Cancer 2020 20:19

    Content type: Research article

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  3. Primary angiosarcomas of the right atrium are extremely rare, often resulted in missed diagnosis or misdiagnosis with routine examination tools. These malignant cardiac tumors are highly aggressive with genera...

    Authors: Yi Yu, Qunshan Wang, Jian Sun, Jing Zhao, Suyun Chen and Yigang Li

    Citation: BMC Cancer 2020 20:13

    Content type: Case report

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  4. We sought to investigate the prognostic value of complete blood count (CBC)-based biomarkers for patients with resectable gastric cancer (GC).

    Authors: Jian-Xian Lin, Jun-Peng Lin, Jian-Wei Xie, Jia-bin Wang, Jun Lu, Qi-Yue Chen, Long-long Cao, Mi Lin, Ruhong Tu, Chao-Hui Zheng, Chang-Ming Huang and Ping Li

    Citation: BMC Cancer 2020 20:11

    Content type: Research article

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  5. Surgery is the only way to cure gastric adenocarcinoma (GAC), and chemotherapy is the basic adjuvant management for GAC. A significant prognostic nomogram for predicting the respective disease-specific surviva...

    Authors: Chao-Yang Wang, Jin Yang, Hao Zi, Zhong-Li Zheng, Bing-Hui Li, Yang Wang, Zheng Ge, Guang-Xu Jian, Jun Lyu, Xiao-Dong Li and Xue-Qun Ren

    Citation: BMC Cancer 2020 20:10

    Content type: Research article

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  6. Ganglioneuromas (GNs) are composed of mature ganglion cells and Schwann cells with a fibrous stroma; GNs are most often observed in children and young adults. The majority of non-cranial GNs are located in the...

    Authors: Chu-Wen Fang, Jyh-Seng Wang, Tony T. Wu and Jen-Tai Lin

    Citation: BMC Cancer 2019 19:1265

    Content type: Case report

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  7. To date, patients with metastasized pancreatic ductal adenocarcinoma (PDAC M1) are regarded as a uniform collective. We hypothesize the existence of oligometastatic disease (OMD): a state of PDAC M1 disease wi...

    Authors: Alexander I. Damanakis, Luisa Ostertag, Dirk Waldschmidt, Fabian Kütting, Alexander Quaas, Patrick Plum, Christiane J. Bruns, Florian Gebauer and Felix Popp

    Citation: BMC Cancer 2019 19:1261

    Content type: Research article

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  8. The application of multiparametric magnetic resonance imaging (mpMRI) for diagnosis of prostate cancer has been recommended by the European Association of Urology (EAU), National Comprehensive Cancer Network (...

    Authors: Liang Zhen, Xiaoqiang Liu, Chen Yegang, Yang Yongjiao, Xu Yawei, Kang Jiaqi, Wang Xianhao, Song Yuxuan, Hu Rui, Zhang Wei and Ou Ningjing

    Citation: BMC Cancer 2019 19:1244

    Content type: Research article

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  9. The aim of this study was to investigate how much the risks of recurrence and death are increased as a consequence of selecting fertility-sparing surgery (FSS) in young women with epithelial ovarian cancer (EOC).

    Authors: Hiroaki Kajiyama, Shiro Suzuki, Nobuhisa Yoshikawa, Michiyasu Kawai, Kimio Mizuno, Osamu Yamamuro, Tetsuro Nagasaka, Kiyosumi Shibata and Fumitaka Kikkawa

    Citation: BMC Cancer 2019 19:1235

    Content type: Research article

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  10. Neoadjuvant chemoradiotherapy is regarded as the standard of treatment for locally advanced lower rectal cancer, although some of these cases are systemic, and distant control may be inadequate. Neoadjuvant ch...

    Authors: Takuya Shiraishi, Takeshi Sasaki, Koji Ikeda, Yuichiro Tsukada, Yuji Nishizawa and Masaaki Ito

    Citation: BMC Cancer 2019 19:1222

    Content type: Research article

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  11. The optimal timing of surgery in relation to chemoradiation is still controversial. Retrospective analysis has demonstrated in the recent decades that the regression of adenocarcinoma can be slow and not compl...

    Authors: Igor Monsellato, Filippo Alongi, Elisa Bertocchi, Stefania Gori, Giacomo Ruffo, Elisa Cassinotti, Ludovica Baldarti, Luigi Boni, Graziano Pernazza, Fabio Pulighe, Carlo De Nisco, Roberto Perinotti, Emilio Morpurgo, Tania Contardo, Enzo Mammano, Ugo Elmore…

    Citation: BMC Cancer 2019 19:1215

    Content type: Study protocol

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    The Correction to this article has been published in BMC Cancer 2020 20:128

  12. We aimed to estimate the stage-specific impact of lymph node dissection (LND) on survival for upper urinary tract urothelial carcinoma (UTUC) patients treated with nephroureterectomy (NU).

    Authors: Ting-Shuai Zhai, Liang Jin, Zhen Zhou, Xiang Liu, Huan Liu, Wei Chen, Jing-Yi Lu, Xu-Dong Yao, Li-Ming Feng and Lin Ye

    Citation: BMC Cancer 2019 19:1207

    Content type: Research article

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  13. In patients diagnosed with ductal carcinoma in situ (DCIS) with needle biopsy before surgery, invasive component (IC) is often found in the postoperative tissue, which results in altered post-surgical care. Ho...

    Authors: Kwan Ho Lee, Jeong Woo Han, Eun Young Kim, Ji Sup Yun, Yong Lai Park and Chan Heun Park

    Citation: BMC Cancer 2019 19:1201

    Content type: Research article

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  14. Glioblastoma multiform (GBM), a malignant brain tumour, has a very often poor prognosis. The therapeutic approach is represented by surgery followed by radiotherapy and chemotherapy. Hypoxia is a factor that c...

    Authors: Vincenzo Gangemi, Chiara Mignogna, Giusy Guzzi, Angelo Lavano, Salvatore Bongarzone, Giuseppe Lucio Cascini and Umberto Sabatini

    Citation: BMC Cancer 2019 19:1197

    Content type: Case report

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  15. An extremely rare condition, radiation-induced angiosarcoma is characterized by a poor prognosis, high recurrence rate and lack of effective treatment. Herein, we present a case report of a 48-year-old female ...

    Authors: Jieshan Guan, Zhijie Luo, Zhiwei Xiao, Yubin Xie and Lizhu Lin

    Citation: BMC Cancer 2019 19:1188

    Content type: Case report

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  16. Precise staging is indispensable to select the appropriate treatment strategy for gastric cancer (GC); however, the diagnostic accuracy of conventional modalities needs to be improved. This study investigated ...

    Authors: Toshiyuki Kosuga, Tomoki Konishi, Takeshi Kubota, Katsutoshi Shoda, Hirotaka Konishi, Atsushi Shiozaki, Kazuma Okamoto, Hitoshi Fujiwara, Michihiro Kudou, Tomohiro Arita, Ryo Morimura, Yasutoshi Murayama, Yoshiaki Kuriu, Hisashi Ikoma, Masayoshi Nakanishi and Eigo Otsuji

    Citation: BMC Cancer 2019 19:1187

    Content type: Research article

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  17. Several multicenter randomized controlled trials comparing laparoscopy and conventional open surgery for colon cancer have demonstrated that laparoscopic approach achieved the same oncological results while im...

    Authors: Gilles Manceau, Antoine Brouquet, Pascal Chaibi, Guillaume Passot, Olivier Bouché, Murielle Mathonnet, Jean-Marc Regimbeau, Rea Lo Dico, Jérémie H. Lefèvre, Frédérique Peschaud, Olivier Facy, Enrico Volpin, Elie Chouillard, Laura Beyert-Berjot, Marc Verny, Mehdi Karoui…

    Citation: BMC Cancer 2019 19:1185

    Content type: Study protocol

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  18. Adrenocortical carcinoma (ACC) is a rare malignant endocrine tumour. Due to a high tumour recurrence rate, the post-operative overall survival (OS) and disease-free survival (DFS) of ACCs is limited. Our resea...

    Authors: Jiayu Liang, Zhihong Liu, Xin Wei, Liang Zhou, Yongquan Tang, Chuan Zhou, Kan Wu, Fuxun Zhang, Fan Zhang, Yiping Lu and Yuchun Zhu

    Citation: BMC Cancer 2019 19:1165

    Content type: Research article

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  19. To compare the efficacy and safety between conventional transarterial chemoembolization (cTACE) and drug-eluting beads TACE (DEB-TACE) in patients with infiltrative hepatocellular carcinoma (iHCC).

    Authors: Zi-shu Zhang, Hui-zhou Li, Cong Ma and Yu-dong Xiao

    Citation: BMC Cancer 2019 19:1162

    Content type: Research article

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  20. Pulmonary sclerosing pneumocytoma (PSP) is a rare benign tumor. Although lymph node metastasis has been reported, it is still considered benign. No malignant transformation has been reported. This is the first...

    Authors: Xiao Teng and Xiaodong Teng

    Citation: BMC Cancer 2019 19:1154

    Content type: Case report

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  21. Conventional cystoscopy can detect advanced stages of bladder cancer; however, it has limitations to detect bladder cancer at the early stages. Fluorocoxib A, a rhodamine-conjugated analog of indomethacin, is ...

    Authors: Jennifer Bourn, Kusum Rathore, Robert Donnell, Wesley White, Md. Jashim Uddin, Lawrence Marnett and Maria Cekanova

    Citation: BMC Cancer 2019 19:1152

    Content type: Research article

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  22. Myeloid sarcoma (MS), also known as chloroma, is an extramedullary manifestation of malignant primitive myeloid cells. Previously, only small studies investigated clinical and imaging features of MS. The purpo...

    Authors: Hans-Jonas Meyer, Wolfram Pönisch, Stefan Andreas Schmidt, Susanne Wienbeck, Friederike Braulke, Dominik Schramm and Alexey Surov

    Citation: BMC Cancer 2019 19:1150

    Content type: Research article

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  23. Neurolymphomatosis (NL) is a direct process of invasion of peripheral nerves by lymphoma. It occurs in roughly 5% of patients with lymphoma and represents a particularly difficult diagnostic dilemma when it is...

    Authors: Pierre R. Bourque, Marcos Loreto Sampaio, Jodi Warman-Chardon, Sam Samaan and Carlos Torres

    Citation: BMC Cancer 2019 19:1149

    Content type: Case report

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  24. To evaluate the clinicopathological and prognostic significance of the percentage change between maximum standardized uptake value (SUVmax) at 60 min (SUVmax1) and SUVmax at 120 min (SUVmax2) (ΔSUVmax%) using dua...

    Authors: Yoji YAMAGISHI, Tomomi KOIWAI, Tamio YAMASAKI, Takahiro EINAMA, Makiko FUKUMURA, Miyuki HIRATSUKA, Takako KONO, Katsumi HAYASHI, Jiro ISHIDA, Hideki UENO and Hitoshi TSUDA

    Citation: BMC Cancer 2019 19:1146

    Content type: Research article

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  25. Recent studies have found that inflammatory response is involved in the pathogenesis of ovarian cancer. Advanced ovarian cancer is often presented with ascites that is rich in cytokines, inflammatory factors o...

    Authors: Jun Shi, Rongfen Huo, Ningli Li, Haichuan Li, Tianhang Zhai, Huidan Li, Baihua Shen, Jing Ye, Ruojin Fu and Wen Di

    Citation: BMC Cancer 2019 19:1140

    Content type: Research article

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  26. Thyroid nodules are frequently detected by cervical ultrasound examinations. In follow-up studies, malignant as well as benign nodules may exhibit an increase in size.

    Authors: Michael Cordes, Theresa Ida Götz, Karen Horstrup, Torsten Kuwert and Christian Schmidkonz

    Citation: BMC Cancer 2019 19:1139

    Content type: Research article

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  27. Early recurrence of hepatocellular carcinoma (HCC) after liver transplantation (LT) is associated with poor surgical outcomes. This study aims to construct a preoperative model to predict individual risk of po...

    Authors: Abdulahad Abdulrab Mohammed Al-Ameri, Xuyong Wei, Lidan Lin, Zhou Shao, Haijun Guo, Haiyang Xie, Lin Zhou, Shusen Zheng and Xiao Xu

    Citation: BMC Cancer 2019 19:1136

    Content type: Research article

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  28. Post-transplant lymphoproliferative disorders (PTLDs) represent a spectrum of heterogenetic lymphoid proliferations. PTLD is a serious complication that affects the long-term survival of kidney transplant pati...

    Authors: Jian-Chao Zhang, Hui-Xia Lan, Hui-Juan Zhao, Yang-Yang Lei, Li Ma, Xiao-Yan Xie, Ming-de Lu and Wei Wang

    Citation: BMC Cancer 2019 19:1135

    Content type: Case report

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  29. Non-muscle-invasive bladder cancer (NMIBC) is the most common neoplasm of the urinary tract and requires life-long invasive surveillance to detect disease recurrence. Currently, there are no effective oral the...

    Authors: Remco J. Molenaar, Jons W. van Hattum, Iris S. Brummelhuis, Jorg R. Oddens, C. Dilara Savci-Heijink, Egbert R. Boevé, Saskia A. van der Meer, J. Fred Witjes, Michael N. Pollak, Theo M. de Reijke and Johanna W. Wilmink

    Citation: BMC Cancer 2019 19:1133

    Content type: Study protocol

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  30. TAE-gene therapy for hepatoma, incorporating the tumor-targeted therapeutic efficacy of trans-arterial embolization, hydroxyapatite nanoparticles (nHAP) and anti-cancer wild-type p53 gene (wt-p53), was present...

    Authors: Gaopeng Li, Wenqin Kang, Mingliang Jin, Lidong Zhang, Jian Zheng, Kai Jia, Jinfeng Ma, Ting Liu, Xueyi Dang, Zhifeng Yan, Zefeng Gao and Jun Xu

    Citation: BMC Cancer 2019 19:1126

    Content type: Research article

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  31. Intracranial metastasis of Gastrointestinal Stromal Tumors (GISTs) is rare but presents unique treatment challenges. We present a case of intracranial metastasis of GIST with a systematic review of the literat...

    Authors: Marc Prablek, Visish M. Srinivasan, Aditya Srivatsan, Stephanie Holdener, Mazen Oneissi, Kent A. Heck, Ali Jalali, Jacob Mandel, Ashwin Viswanathan and Akash J. Patel

    Citation: BMC Cancer 2019 19:1119

    Content type: Case report

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  33. Multiple endocrine neoplasia type 1 (MEN1) is a rare autosomal dominant inherited condition affecting multiple endocrine organs, resulting in significant morbidity and decreased life expectancy. Early tumor id...

    Authors: Lei Lou, Lixia Zhou, Wenyan Wang, Huina Li and Yuehong Li

    Citation: BMC Cancer 2019 19:1107

    Content type: Case report

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  35. The aim of this study was to assess the agreement rate between intraoperative evaluation (IOE) and final diagnosis (FD) in a series of surgically resected endometrial carcinoma (EC), with a preoperative ambigu...

    Authors: A. Santoro, A. Piermattei, F. Inzani, G. Angelico, M. Valente, D. Arciuolo, S. Spadola, M. Martini, F. Fanfani, A. Fagotti, V. Gallotta, G. Scambia and G. F. Zannoni

    Citation: BMC Cancer 2019 19:1096

    Content type: Research article

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  36. We designed a retrospective study to compare prognostic outcomes based on whether or not surgical resection was performed in elderly patients aged(≥75 years) with resectable pancreatic cancer.

    Authors: Hyeong Min Park, Sang-Jae Park, Sung-Sik Han and Seoung Hoon Kim

    Citation: BMC Cancer 2019 19:1090

    Content type: Research article

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  37. High perioperative morbidity, mortality, and uncertain outcome of surgery in octogenarians with proximal gastric carcinoma (PGC) pose a dilemma for both patients and physicians. We aim to evaluate the risks an...

    Authors: Xuefei Wang, Junjie Zhao, Mark Fairweather, Tingsong Yang, Yihong Sun and Jiping Wang

    Citation: BMC Cancer 2019 19:1079

    Content type: Research article

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  38. Increase of circulating tumor cells (CTCs) has been found after surgery for various carcinomas but not confirmed for breast cancer, and whether endoscopic surgery confers identical effect to CTCs as open surge...

    Authors: Shichao Li, Wenting Yan, Xinhua Yang, Li Chen, Linjun Fan, Haoxi Liu, Kun Liu, Yi Zhang and Jun Jiang

    Citation: BMC Cancer 2019 19:1070

    Content type: Research article

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  40. The computed tomography (CT) features of small solid lung cancers and their changing regularity as they grow have not been well studied. The purpose of this study was to analyze the CT features of solid lung c...

    Authors: Zhi-gang Chu, Yan Zhang, Wang-jia Li, Qi Li, Yi-neng Zheng and Fa-jin Lv

    Citation: BMC Cancer 2019 19:1060

    Content type: Research article

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  42. Most lymph node metastasis (LNM) models for early gastric cancer (EGC) include lymphovascular invasion (LVI) as a predictor. However, LVI must be confirmed by postoperative pathology. In this study, we aimed t...

    Authors: Jian-Xian Lin, Zu-Kai Wang, Wei Wang, Jacopo Desiderio, Jian-Wei Xie, Jia-Bin Wang, Jun Lu, Qi-Yue Chen, Long-Long Cao, Mi Lin, Ru-Hong Tu, Chao-Hui Zheng, Ping Li, Amilcare Parisi, Zhi-Wei Zhou and Chang-Ming Huang

    Citation: BMC Cancer 2019 19:1048

    Content type: Research article

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  43. The application of laparoscopic liver resection (LLR) has expanded rapidly in recent decades. Although multiple authors have reported LLR shows improved safety and efficacy in treating hepatocellular carcinoma...

    Authors: Zi-Yu Wang, Qing-Lian Chen, Ling-Ling Sun, Shu-Ping He, Xiao-Fen Luo, Li-Shuang Huang, Jun-Hai Huang, Cheng-Ming Xiong and Chong Zhong

    Citation: BMC Cancer 2019 19:1047

    Content type: Research article

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  44. Assessment of preoperative general condition to predict postoperative outcomes is important, particularly in older patients who typically suffer from various comorbidities and exhibit impaired functional statu...

    Authors: Yuka Ahiko, Dai Shida, Tomoko Horie, Taro Tanabe, Yasuyuki Takamizawa, Ryohei Sakamoto, Konosuke Moritani, Shunsuke Tsukamoto and Yukihide Kanemitsu

    Citation: BMC Cancer 2019 19:946

    Content type: Research article

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  45. Radiological imaging plays a central role in the diagnosis of breast cancer (BC). Some studies suggest MRI techniques like diffusion weighted imaging (DWI) may provide further prognostic value by discriminatin...

    Authors: Alexey Surov, Yun-Woo Chang, Lihua Li, Laura Martincich, Savannah C. Partridge, Jin You Kim and Andreas Wienke

    Citation: BMC Cancer 2019 19:1043

    Content type: Research article

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  46. The ultimate goal of locoregional therapy (LRT) to the liver is to induce total tumor necrosis. Trans-arterial chemoembolization (TACE) is the mainstay bridging therapy for patients with hepatocellular carcino...

    Authors: Wei Zhang, An-Hui Xu, Wei Wang, Yan-Hui Wu, Qian-Ling Sun and Chang Shu

    Citation: BMC Cancer 2019 19:1041

    Content type: Research article

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  48. Many data suggest that patients with low rectal adenocarcinoma who achieved ypT0N0 status have improved survival and disease-free survival (DFS) compared to all other stages however only few data are available...

    Authors: Amine Souadka, Mohammed Anass Majbar, Amine Benkabbou, Badr Serji, Tarik Souiki, Sidi Mohammed Bouchentouf, Mourad Abid, Basma El Khannousi, Tijani El Harroudi, Hadj Omar El Malki, Mohammed Raiss, Lahsen Ifrine, Khalid Mazaz, Aziz Zentar, Raouf Mohsine, Abdelilah Souadka…

    Citation: BMC Cancer 2019 19:1008

    Content type: Research article

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  49. Amputation is the standard of care even for early-stage subungual melanomas (SUMs), known as nail apparatus melanoma, because the nail bed and nail matrix are close to the distal phalanx. However, a recent stu...

    Authors: Kiyo Tanaka, Yasuhiro Nakamura, Tomonori Mizutani, Taro Shibata, Arata Tsutsumida, Haruhiko Fukuda, Shigeto Matsushita, Megumi Aoki, Kenjiro Namikawa, Shuichi Ohe, Satoshi Fukushima and Naoya Yamazaki

    Citation: BMC Cancer 2019 19:1002

    Content type: Study protocol

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  50. Overexpression of epidermal growth factor receptor (EGFR) has been established as a valid therapeutic target of non-small cell lung cancer (NSCLC). However, the clinical benefit of cetuximab as an EGFR-targeti...

    Authors: Aiko Yamaguchi, Arifudin Achmad, Hirofumi Hanaoka, Yusri Dwi Heryanto, Anu Bhattarai, Ratianto, Erdene Khongorzul, Rini Shintawati, A. Adhipatria P. Kartamihardja, Ayaka Kanai, Yumi Sugo, Noriko S. Ishioka, Tetsuya Higuchi and Yoshito Tsushima

    Citation: BMC Cancer 2019 19:1000

    Content type: Research article

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