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Surgical oncology, cancer imaging, and interventional therapeutics

Section edited by Stephen P. Povoski

This section focuses on clinical research that impacts on the diagnosis and treatment of cancer using surgery, diagnostic imaging, interventional therapeutics, and surgical pathology.

Page 12 of 13

  1. Myoepithelial carcinoma (MEC) is a rare salivary gland tumor. Its long-term prognosis remains unknown because of the paucity of reported cases with long-term follow-up. Although some case series exist, the cli...

    Authors: Takahiro Wakasaki, Marie Kubota, Yutaka Nakashima, Eri Tomonobe, Takenao Mihara and Junichi Fukushima

    Citation: BMC Cancer 2016 16:827

    Content type: Case report

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  2. To evaluate the accuracy of sentinel lymph node biopsy (SLNB) after neoadjuvant chemotherapy (NAC) in breast cancer patients with axillary lymph node (ALN) metastasis.

    Authors: Yue Yu, Ning Cui, Heng-Yu Li, Yan-Mei Wu, Lu Xu, Min Fang and Yuan Sheng

    Citation: BMC Cancer 2016 16:808

    Content type: Research article

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  3. Gemcitabine is currently the standard chemotherapy for the adjuvant treatment of pancreatic cancer. This chemotherapeutic agent is generally well-tolerated, myelosuppression and gastrointestinal toxicity being...

    Authors: Elisabetta Fenocchio, Ilaria Depetris, Delia Campanella, Lucia Garetto, Fabrizio Carnevale Schianca, Danilo Galizia, Giovanni Grignani, Massimo Aglietta and Francesco Leone

    Citation: BMC Cancer 2016 16:793

    Content type: Case report

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  4. Pancreatic cancer is among the top 5 most common cancers worldwide, but is particularly devastating due to its insidious nature. Complete surgical resection remains the only potential curative treatment, altho...

    Authors: Mišo Gostimir, Sean Bennett, Terence Moyana, Harman Sekhon and Guillaume Martel

    Citation: BMC Cancer 2016 16:786

    Content type: Case report

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  5. Surgery for advanced gastric cancer (AGC) often includes dissection of splenic hilar lymph nodes (SHLNs). This study compared the safety and effectiveness of different approaches to SHLN dissection for upper- ...

    Authors: Xin Ji, Tao Fu, Zhao-De Bu, Ji Zhang, Xiao-Jiang Wu, Xiang-Long Zong, Zi-Yu Jia, Biao Fan, Yi-Nan Zhang and Jia-Fu Ji

    Citation: BMC Cancer 2016 16:765

    Content type: Research article

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  6. Arterial hyperenhancement and washout on computed tomography and magnetic resonance imaging (MRI) are described by all major guidelines as specific criteria for non-invasive diagnosis of hepatocellular carcino...

    Authors: Roman Kloeckner, Daniel Pinto dos Santos, Karl-Friedrich Kreitner, Anne Leicher-Düber, Arndt Weinmann, Jens Mittler and Christoph Düber

    Citation: BMC Cancer 2016 16:758

    Content type: Research article

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  7. A totally implantable venous access device (TIVAD) provides reliable, long-term vascular access and improves patients’ quality of life. The wide use of TIVADs is associated with important complications. A meta...

    Authors: Shaoyong Wu, Jingxiu Huang, Zongming Jiang, Zhimei Huang, Handong Ouyang, Li Deng, Wenqian Lin, Jin Guo and Weian Zeng

    Citation: BMC Cancer 2016 16:747

    Content type: Research article

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  8. Sequential biopsy of breast cancer is used to assess biomarker effects and drug efficacy. The preoperative “window of opportunity” setting is advantageous to test biomarker changes in response to therapeutic a...

    Authors: Sirwan M. Hadad, Lee B. Jordan, Pankaj G. Roy, Colin A. Purdie, Takayuki Iwamoto, Lajos Pusztai, Stacy L. Moulder-Thompson and Alastair M. Thompson

    Citation: BMC Cancer 2016 16:745

    Content type: Research article

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  9. The incidence rate has been increasing for superficial head and neck squamous cell carcinoma (HNSCC) discovered through surveillance endoscopic study using narrow band imaging (NBI), a procedure mainly used fo...

    Authors: Hiroshi Nakamura, Tomonori Yano, Satoshi Fujii, Tomohiro Kadota, Toshifumi Tomioka, Takeshi Shinozaki, Ryuichi Hayashi and Kazuhiro Kaneko

    Citation: BMC Cancer 2016 16:743

    Content type: Research article

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  10. In Germany, most breast cancer patients are treated in specialized breast cancer units (BCU), which are certified, and routinely monitored. Herein, we evaluate up-to-date oncological outcome of breast cancer (...

    Authors: André Hennigs, Fabian Riedel, Adam Gondos, Peter Sinn, Peter Schirmacher, Frederik Marmé, Dirk Jäger, Hans-Ulrich Kauczor, Anne Stieber, Katja Lindel, Jürgen Debus, Michael Golatta, Florian Schütz, Christof Sohn, Jörg Heil and Andreas Schneeweiss

    Citation: BMC Cancer 2016 16:734

    Content type: Research article

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  11. Lung cancer is usually presented with cough, dyspnea, pain and weight loss, which is overlapping with symptoms of other lung diseases such as pulmonary fibrosis. Pulmonary fibrosis shows characteristic reticul...

    Authors: Bakir Mehić, Lina Duranović Rayan, Nurija Bilalović, Danina Dohranović Tafro and Ilijaz Pilav

    Citation: BMC Cancer 2016 16:729

    Content type: Case report

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  12. The purpose of this study was to investigate the impact of the Controlling Nutritional Status (CONUT) score on survival compared with the platelet to lymphocyte ratio (PLR), the neutrophil to lymphocyte ratio ...

    Authors: Takahiro Toyokawa, Naoshi Kubo, Tatsuro Tamura, Katsunobu Sakurai, Ryosuke Amano, Hiroaki Tanaka, Kazuya Muguruma, Masakazu Yashiro, Kosei Hirakawa and Masaichi Ohira

    Citation: BMC Cancer 2016 16:722

    Content type: Research article

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  13. The role of laparoscopic resection in patients with clinically suspicious T4 colorectal cancer remains controversial. The aim of this study was to compare the long-term and oncologic outcomes of laparoscopic r...

    Authors: Jong Seob Park, Jung Wook Huh, Yoon Ah Park, Yong Beom Cho, Seong Hyeon Yun, Hee Cheol Kim, Woo Yong Lee and Ho-Kyung Chun

    Citation: BMC Cancer 2016 16:714

    Content type: Research article

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  14. Hepatocellular carcinoma (HCC) patients with hepatic vein tumor thrombosis (HVTT) extending to the inferior vena cava (IVC) have an extremely poor prognosis. Here we report a case of HCC with HVTT and renal dy...

    Authors: Atene Itoh, Hiroshi Sadamori, Kazuhisa Yabushita, Kazuteru Monden, Masashi Tatsukawa, Masayoshi Hioki, Tsuyoshi Hyodo, Kunihiro Omonishi, Toru Ueki, Satoshi Ohno, Kohsaku Sakaguchi and Norihisa Takakura

    Citation: BMC Cancer 2016 16:705

    Content type: Case report

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  15. The efficacy of the classical treatment modalities surgery and radiotherapy in the treatment of aggressive fibromatosis is presently disputed and there is a shift towards a more conservative approach. The aim ...

    Authors: Danique L.M. van Broekhoven, Dirk J. Grünhagenl, Thijs van Dalen, Frits van Coevorden, Han J. Bonenkamp, Lukas B. Been, Marc H.A. Bemelmans, Sander D.S. Dijkstra, Chiara Colombo, Alessandro Gronchi and Cornelis Verhoef

    Citation: BMC Cancer 2016 16:686

    Content type: Study protocol

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  16. The aims of this study were to evaluate the impact of initial uterus-preserving surgery, such as myomectomy or subtotal hysterectomy, on the recurrence rates of patients with uterine sarcoma found incidentally...

    Authors: Jung-Yun Lee, Hyun Soo Kim, Eun Ji Nam, Sang Wun Kim, Sunghoon Kim and Young Tae Kim

    Citation: BMC Cancer 2016 16:675

    Content type: Research article

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  17. The Response Evaluation Criteria in Solid Tumors (RECIST) are the current standard for evaluating disease progression or therapy response in patients with solid tumors. RECIST 1.1 calls for axial, longest-diam...

    Authors: Kathleen E. Fenerty, Les R. Folio, Nicholas J. Patronas, Jennifer L. Marté, James L. Gulley and Christopher R. Heery

    Citation: BMC Cancer 2016 16:672

    Content type: Research article

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  18. The predictive accuracy of the American Joint Committee on Cancer (AJCC) stages of colorectal cancer (CRC) is mediocre. This study aimed to develop postoperative nomograms to predict cancer-specific survival (...

    Authors: Zhen-yu Zhang, Qi-feng Luo, Xiao-wei Yin, Zhen-ling Dai, Shiva Basnet and Hai-yan Ge

    Citation: BMC Cancer 2016 16:658

    Content type: Research article

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  19. Methotrexate-associated lymphoproliferative disorder (MTX-LPD) is a benign lymphoid proliferation or malignant lymphoma in patients who have been treated with MTX. MTX withdrawal and observation for a short pe...

    Authors: Shiro Watanabe, Osamu Manabe, Kenji Hirata, Noriko Oyama-Manabe, Naoya Hattori, Yasuka Kikuchi, Kentaro Kobayashi, Takuya Toyonaga and Nagara Tamaki

    Citation: BMC Cancer 2016 16:635

    Content type: Research article

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  20. Variable degrees of differentiation in hepatocellular carcinoma(HCC)under Edmondson-Steiner grading system has been proven to be an independent prognostic indicator for HCC. Up till now, there has been no effe...

    Authors: Zhenpeng Peng, Mengjie Jiang, Huasong Cai, Tao Chan, Zhi Dong, Yanji Luo, Zi-Ping Li and Shi-Ting Feng

    Citation: BMC Cancer 2016 16:625

    Content type: Research article

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  21. The response to neoadjuvant chemotherapy has been proven to predict long-term clinical benefits for patients. Our research is to construct a nomogram to predict pathological complete response of human epiderma...

    Authors: Xi Jin, Yi-Zhou Jiang, Sheng Chen, Ke-Da Yu, Ding Ma, Wei Sun, Zhi-Min Shao and Gen-Hong Di

    Citation: BMC Cancer 2016 16:606

    Content type: Research article

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  22. Lymphedema is a prevalent long-term effect of breast cancer treatment that is associated with reduced quality of life. More recent observational data suggest that the addition of night-time compression to day-...

    Authors: Margaret L. McNeely, Kristin L. Campbell, Marc Webster, Urve Kuusk, Karen Tracey and John Mackey

    Citation: BMC Cancer 2016 16:601

    Content type: Study protocol

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  23. In the lung, melanoma is mostly arranged as patterns of multiple nodules, solitary nodules, or miliary invasions. Very rarely, it also displays a “crazy paving” pattern (also described as a “paving stone,” “fl...

    Authors: Yikuan Feng, Jianping Zhao, Qun Yang, Weining Xiong, Guohua Zhen, Yongjian Xu, Zhenxiang Zhang and Huilan Zhang

    Citation: BMC Cancer 2016 16:592

    Content type: Case report

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  24. Liver biopsies in pediatric hematopoietic stem cell transplantation (HSCT) patients are as and effective when performed at bedside in the Bone Marrow Transplant Unit (BMTU) than in the Day Surgery Unit (DSU), ...

    Authors: Natalia Maximova, Massimo Gregori, Francesca Barbieri, Antonio Pizzol and Aurelio Sonzogni

    Citation: BMC Cancer 2016 16:590

    Content type: Research article

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  25. Total laryngectomy with or without adjuvant (chemo)radiation often induces speech, swallowing and neck and shoulder problems. Speech, swallowing and shoulder exercises may prevent or diminish these problems. T...

    Authors: Femke Jansen, Ingrid C. Cnossen, Simone E. J. Eerenstein, Veerle M. H. Coupé, Birgit I. Witte, Cornelia F. van Uden-Kraan, Patricia Doornaert, Weibel W. Braunius, Remco De Bree, José A. U. Hardillo, Jimmie Honings, György B. Halmos, C. René Leemans and Irma M. Verdonck-de Leeuw

    Citation: BMC Cancer 2016 16:580

    Content type: Study protocol

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  26. Volume-based parameters, such as metabolic tumor volume (MTV) and total lesion glycolysis (TLG), on F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) are useful for predicting treatment response...

    Authors: Tomoka Kitao, Kenji Hirata, Katsumi Shima, Takashi Hayashi, Mitsunori Sekizawa, Toshiki Takei, Wataru Ichimura, Masao Harada, Keishi Kondo and Nagara Tamaki

    Citation: BMC Cancer 2016 16:576

    Content type: Research article

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  27. The distinction between right-sided and left-sided colon cancer has recently received considerable attention due to differences regarding underlying genetic mutations. There is an ongoing debate if right- vers...

    Authors: Rene Warschkow, Michael C. Sulz, Lukas Marti, Ignazio Tarantino, Bruno M. Schmied, Thomas Cerny and Ulrich Güller

    Citation: BMC Cancer 2016 16:554

    Content type: Research article

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  28. Ganglioneuroma (GN) and ganglioneuroblastoma intermixed (GNBI) are mature variants of neuroblastic tumors (NT). It is still discussed whether incomplete resection of GN/GNBI impairs the outcome of patients.

    Authors: Boris Decarolis, Thorsten Simon, Barbara Krug, Ivo Leuschner, Christian Vokuhl, Peter Kaatsch, Dietrich von Schweinitz, Thomas Klingebiel, Ingo Mueller, Lothar Schweigerer, Frank Berthold and Barbara Hero

    Citation: BMC Cancer 2016 16:542

    Content type: Research article

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  29. Prostate cancer (PC) is a major health concern for men worldwide, with an estimated lifetime risk of ~14 %. A recent comprehensive analysis of mutational processes revealed ageing and mismatch repair as the on...

    Authors: Lynne Kerr, Matthew J. Rewhorn, Mark Longmuir, Sioban Fraser, Shaun Walsh, Nicola Andrew and Hing Y. Leung

    Citation: BMC Cancer 2016 16:529

    Content type: Research article

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  30. Binding to Sema4D and PlexinB1 induce angiogenesis and invasive growth in colorectal cancer (CRC). The expression of Semaphorin4D (Sema4D) and PlexinB1 has been shown to be related to the prognosis of patients...

    Authors: Tetsuro Ikeya, Kiyoshi Maeda, Hisashi Nagahara, Masatsune Shibutani, Yasuhito Iseki and Kosei Hirakawa

    Citation: BMC Cancer 2016 16:525

    Content type: Research article

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  31. The chemokine CXCL12 and its corresponding receptor CXCR4 are key players in the development of several cancers. Therefore, we hypothesized that there is a functional causality between CXCL12 expression and tu...

    Authors: Yusuke Uchi, Hiroya Takeuchi, Sachiko Matsuda, Yoshiro Saikawa, Hirofumi Kawakubo, Norihito Wada, Tsunehiro Takahashi, Rieko Nakamura, Kazumasa Fukuda, Tai Omori and Yuko Kitagawa

    Citation: BMC Cancer 2016 16:514

    Content type: Research article

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  32. Rectal cancer surgery is accompanied with high morbidity and poor long term functional outcome. Screening programs have shown a shift towards more early staged cancers. Patients with early rectal cancer can po...

    Authors: W. A. A. Borstlap, P. J. Tanis, T. W. A. Koedam, C. A. M. Marijnen, C. Cunningham, E. Dekker, M. E. van Leerdam, G. Meijer, N. van Grieken, I. D. Nagtegaal, C. J. A. Punt, M. G. W. Dijkgraaf, J. H. De Wilt, G. Beets, E. J. de Graaf, A. A. W van Geloven…

    Citation: BMC Cancer 2016 16:513

    Content type: Study protocol

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  33. Synovial sarcoma (SS) is a soft tissue sarcoma of unknown histogenesis. Most metastatic or unresectable cases are incurable. Novel antitumor agents and precise prognostication are needed for SS patients. The p...

    Authors: Akira Maekawa, Kenichi Kohashi, Masaaki Kuda, Kunio Iura, Takeaki Ishii, Makoto Endo, Tetsuya Nakatsura, Yukihide Iwamoto and Yoshinao Oda

    Citation: BMC Cancer 2016 16:511

    Content type: Research article

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  34. Occult invasive cervical cancer (OICC) is sometimes incidentally found in surgical specimens after a simple hysterectomy (SH). This study was aimed at identifying a subset of patients with OICC who have a favo...

    Authors: Huimin Bai, Dongyan Cao, Fang Yuan, Huilan Wang, Jie Chen, Yue Wang, Keng Shen and Zhenyu Zhang

    Citation: BMC Cancer 2016 16:507

    Content type: Research article

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  35. This study was carried out to determine the prognostic significance of preoperative peripheral epithelial cell adhesion molecule- positive (EpCAM +) circulating tumor cell (CTC) and T ...

    Authors: Yan Zhou, Beili Wang, Jiong Wu, Chunyan Zhang, Yiwen Zhou, XinRong Yang, Jian Zhou, Wei Guo and Jia Fan

    Citation: BMC Cancer 2016 16:506

    Content type: Research article

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  36. The 2010 guidelines of the French National Cancer Institute (INCa) classify patients with endometrial cancer into three risk groups for lymph node invasion and recurrence on the basis of MRI and histological a...

    Authors: Noemie Body, Vincent Lavoué, Olivier De Kerdaniel, Fabrice Foucher, Sébastien Henno, Aurélie Cauchois, Bruno Laviolle, Marc Leblanc and Jean Levêque

    Citation: BMC Cancer 2016 16:498

    Content type: Research article

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  37. The purpose of this retrospective study was to evaluate the efficacy of incorporating trans-arterial radioembolization (TARE) with systemic chemotherapy in the treatment of liver-dominant metastatic pancreatic...

    Authors: Alexander Y. Kim, Keith Unger, Hongkun Wang and Michael J. Pishvaian

    Citation: BMC Cancer 2016 16:492

    Content type: Research article

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  38. Platelet and blood coagulation abnormalities frequently occur in cancer patients. Fibrinogen is an important hemostatic factor that regulates the hemostatic pathway. Hyperfibrinogenemia is increasing recognize...

    Authors: Xuefeng Yu, Fulan Hu, Qiang Yao, Chunfeng Li, Hongfeng Zhang and Yingwei Xue

    Citation: BMC Cancer 2016 16:480

    Content type: Research article

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  39. The clinicopathological features and prognosis of gastric cancer in young patients are both limited and controversial. Therefore, the aim of this study was to define the clinicopathological features and progno...

    Authors: Shushang Liu, Fan Feng, Guanghui Xu, Zhen Liu, Yangzi Tian, Man Guo, Xiao Lian, Lei Cai, Daiming Fan and Hongwei Zhang

    Citation: BMC Cancer 2016 16:478

    Content type: Research article

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  40. Mammography and ultrasound are the gold standard imaging techniques for preoperative assessment and for monitoring the efficacy of neoadjuvant chemotherapy in breast cancer. Maximum accuracy in predicting path...

    Authors: Roland Gregor Stein, Daniel Wollschläger, Rolf Kreienberg, Wolfgang Janni, Manfred Wischnewsky, Joachim Diessner, Tanja Stüber, Catharina Bartmann, Mathias Krockenberger, Jörg Wischhusen, Achim Wöckel, Maria Blettner and Lukas Schwentner

    Citation: BMC Cancer 2016 16:459

    Content type: Research article

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  41. Diagnosing breast cancer during the early stage may be helpful for decreasing cancer-related mortality. In Western developed countries, mammographies have been the gold standard for breast cancer detection. Ho...

    Authors: Xiuyan Yu, Guoming Hu, Zhigang Zhang, Fuming Qiu, Xuan Shao, Xiaochen Wang, Hongwei Zhan, Yiding Chen, Yongchuan Deng and Jian Huang

    Citation: BMC Cancer 2016 16:450

    Content type: Research article

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  42. Our aim was to investigate the influence of FTS on human cellular and humoral immunity using a randomized controlled clinical study in esophageal cancer patients.

    Authors: Lantao Chen, Lixin Sun, Yaoguo Lang, Jun Wu, Lei Yao, Jinfeng Ning, Jinfeng Zhang and Shidong Xu

    Citation: BMC Cancer 2016 16:449

    Content type: Research article

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  43. Intraocular iris rhabdomyosarcoma is extremely rare, and in the 3 cases reported to date occurred as the primary site of tumour growth. We report a case of rhabdomyosarcoma of the foot metastasizing to the iris.

    Authors: Ido Didi Fabian, G. Darius Hildebrand, Shaun Wilson, Tina Foord and Mandeep S. Sagoo

    Citation: BMC Cancer 2016 16:447

    Content type: Case report

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  44. Multiple myeloma osteolytic disease affecting the spine results in vertebral compression fractures. These are painful, result in kyphosis, and impact respiratory function and quality of life. We explore the im...

    Authors: Karan Malhotra, Joseph S. Butler, Hai Ming Yu, Susanne Selvadurai, Shirley D’Sa, Neil Rabin, Charalampia Kyriakou, Kwee Yong and Sean Molloy

    Citation: BMC Cancer 2016 16:444

    Content type: Research article

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  45. Recent large trials have shown the survival benefits of 10-year use of tamoxifen by reducing late recurrence compared with 5-year therapy in estrogen receptor(ER)-positive breast cancer. We tried to identify c...

    Authors: Eun-Shin Lee, Wonshik Han, Min Kyoon Kim, Jongjin Kim, Tae-kyung Yoo, Moo Hyun Lee, Kyung Hun Lee, Tae Yong Kim, Hyeong-Gon Moon, Seock-Ah Im, Dong-Young Noh and Eun Sook Lee

    Citation: BMC Cancer 2016 16:430

    Content type: Research article

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  46. Detecting superficial head and neck squamous cell carcinoma (HNSCC) by endoscopy is challenging because of limited morphological hallmarks, and iodine cannot be applied to head and neck lesions due to severe m...

    Authors: Takeshi Mizushima, Shunsuke Ohnishi, Yuichi Shimizu, Yutaka Hatanaka, Kanako C. Hatanaka, Hidetaka Hosono, Yoshimasa Kubota, Mitsuteru Natsuizaka, Mako Kamiya, Shouko Ono, Akihiro Homma, Mototsugu Kato, Naoya Sakamoto and Yasuteru Urano

    Citation: BMC Cancer 2016 16:411

    Content type: Research article

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  47. Prostate cancer (PCa) is the most common non-skin cancer in USA and the second leading cause of cancer death in Western Countries. Despite the high mortality associated with PCa, the only established risk fact...

    Authors: Cosimo De Nunzio, Giuseppe Simone, Aldo Brassetti, Riccardo Mastroianni, Devis Collura, Giovanni Muto, Michele Gallucci and Andrea Tubaro

    Citation: BMC Cancer 2016 16:407

    Content type: Research article

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