Skip to main content

Surgical oncology, cancer imaging, and interventional therapeutics

Section edited by Stephen P. Povoski

This section focuses on clinical research that impacts on the diagnosis and treatment of cancer using surgery, diagnostic imaging, interventional therapeutics, and surgical pathology.

Page 11 of 13

  1. Cosmetic result following breast conserving surgery (BCS) for cancer influences quality of life and psychosocial functioning in breast cancer patients. A preoperative prediction of expected cosmetic result fol...

    Authors: M. Lagendijk, E. L. Vos, A. H. J. Koning, M. G. M. Hunink, J. P. Pignol, E. M. L. Corten, C. de Monye, C. H. M. van Deurzen, J. H. van Dam, W. W. Vrijland, C. M. E. Contant, C. Verhoef, W. van Lankeren and L. B. Koppert

    Citation: BMC Cancer 2017 17:336

    Content type: Study protocol

    Published on:

  2. Lymphatic vessel density and lymphovascular invasion are commonly assessed to identify the clinicopathological outcomes in breast cancer. However, the prognostic values of them on patients’ survival are still ...

    Authors: Song Zhang, Dong Zhang, Mingfu Gong, Li Wen, Cuiwei Liao and Liguang Zou

    Citation: BMC Cancer 2017 17:335

    Content type: Research article

    Published on:

  3. In the primary analysis of the ERIVANCE BCC trial, vismodegib, the first US Food and Drug Administration–approved Hedgehog pathway inhibitor, showed objective response rates (ORRs) by independent review facili...

    Authors: Aleksandar Sekulic, Michael R. Migden, Nicole Basset-Seguin, Claus Garbe, Anja Gesierich, Christopher D. Lao, Chris Miller, Laurent Mortier, Dedee F. Murrell, Omid Hamid, Jorge F. Quevedo, Jeannie Hou, Edward McKenna, Natalie Dimier, Sarah Williams, Dirk Schadendorf…

    Citation: BMC Cancer 2017 17:332

    Content type: Research article

    Published on:

    The Correction to this article has been published in BMC Cancer 2019 19:366

  4. Based on promising results from a Phase I study of hepatic arterial infusion chemotherapy using a combination of miriplatin and cisplatin powder (DDP-H) for unresectable hepatocellular carcinoma (UMIN-CTR00000...

    Authors: Kenya Kamimura, Takeshi Suda, Takeshi Yokoo, Hiroteru Kamimura, Tsutomu Kanefuji, Atsunori Tsuchiya, Masaaki Takamura, Hirokazu Kawai, Nobuo Waguri, Satoshi Yamagiwa and Shuji Terai

    Citation: BMC Cancer 2017 17:322

    Content type: Research article

    Published on:

  5. The association between lymphovascular invasion and lymphatic or hematogenous metastasis has been suspected, with conflicting evidence. We have investigated the association between the risk of biochemical recu...

    Authors: Yong Jin Kang, Hyun-Soo Kim, Won Sik Jang, Jong Kyou Kwon, Cheol Yong Yoon, Joo Yong Lee, Kang Su Cho, Won Sik Ham and Young Deuk Choi

    Citation: BMC Cancer 2017 17:321

    Content type: Research article

    Published on:

  6. To evaluate the procedures and complications of diaphragm peritonectomy (DP) and diaphragm full-thickness resection (DFTR) during primary cytoreduction for advanced stage epithelial ovarian cancer.

    Authors: Shuang Ye, Tiancong He, Shanhui Liang, Xiaojun Chen, Xiaohua Wu, Huijuan Yang and Libing Xiang

    Citation: BMC Cancer 2017 17:317

    Content type: Research article

    Published on:

  7. To determine the proportion of “true” interval cancers and tumor characteristics of interval breast cancers prior to, during and after the transition from screen-film mammography screening (SFM) to full-field ...

    Authors: Rob M. G. van Bommel, Roy Weber, Adri C. Voogd, Joost Nederend, Marieke W. J. Louwman, Dick Venderink, Luc J. A. Strobbe, Matthieu J. C. Rutten, Menno L. Plaisier, Paul N. Lohle, Marianne J. H. Hooijen, Vivianne C.G. Tjan-Heijnen and Lucien E. M. Duijm

    Citation: BMC Cancer 2017 17:315

    Content type: Research article

    Published on:

  8. Vascular invasion, including microvascular invasion (MVI) and portal vein tumor thrombus (PVTT), is associated with the postoperative recurrence of hepatocellular carcinoma (HCC). We aimed to investigate the p...

    Authors: Xubiao Wei, Nan Li, Shanshan Li, Jie Shi, Weixing Guo, Yaxin Zheng and Shuqun Cheng

    Citation: BMC Cancer 2017 17:304

    Content type: Research article

    Published on:

  9. Rapid and accurate cancer staging following diagnosis underpins patient management, in particular the identification of distant metastatic disease. Current staging guidelines recommend sequential deployment of...

    Authors: Stuart A. Taylor, Sue Mallett, Anne Miles, Sandy Beare, Gauraang Bhatnagar, John Bridgewater, Rob Glynne-Jones, Vicky Goh, Ashley M. Groves, Sam M. Janes, Dow Mu Koh, Steve Morris, Alison Morton, Neal Navani, Alf Oliver, Anwar R. Padhani…

    Citation: BMC Cancer 2017 17:299

    Content type: Study protocol

    Published on:

  10. Thyroglobulin measurement with fine-needle aspiration (Tg-FNA) is a sensitive method for detecting metastatic papillary thyroid carcinoma (PTC). However, the diagnostic threshold is not well established and th...

    Authors: Huan Zhao, Yong Wang, Min-jie Wang, Zhi-hui Zhang, Hai-rui Wang, Bing Zhang and Hui-qin Guo

    Citation: BMC Cancer 2017 17:296

    Content type: Research article

    Published on:

  11. The theory of extravasated platelet aggregation in cancer lesions was recently introduced. We investigated the association of platelet aggregation in gastric cancer stroma with clinicopathological features, ch...

    Authors: Hiroto Saito, Sachio Fushida, Tomoharu Miyashita, Katsunobu Oyama, Takahisa Yamaguchi, Tomoya Tsukada, Jun Kinoshita, Hidehiro Tajima, Itasu Ninomiya and Tetsuo Ohta

    Citation: BMC Cancer 2017 17:294

    Content type: Research article

    Published on:

  12. Women with breast cancer undergoing chemotherapy suffer from a number of symptoms and report receiving inadequate support from health care professionals. Innovative and easily accessible interventions are lack...

    Authors: Jiemin Zhu, Lyn Ebert, Xiangyu Liu and Sally Wai-Chi Chan

    Citation: BMC Cancer 2017 17:291

    Content type: Study protocol

    Published on:

  13. We observed red autofluorescence emanating from bronchial cancer lesions using a sensitive color-fluorescence endoscopy system. We investigated to clarify the origin of the red autofluorescence.

    Authors: Yoshinobu Ohsaki, Takaaki Sasaki, Satoshi Endo, Masahiro Kitada, Shunsuke Okumura, Noriko Hirai, Yoshihiro Kazebayashi, Eri Toyoshima, Yasushi Yamamoto, Kaneyoshi Takeyama, Susumu Nakajima and Isao Sakata

    Citation: BMC Cancer 2017 17:289

    Content type: Research article

    Published on:

  14. Patients with unresectable malignant biliary obstruction have limited life expectancy because of limited stent patency and tumor progression. The aim of our study was to retrospectively evaluate the safety and...

    Authors: Wei Cui, Wenzhe Fan, Mingjian Lu, Yingqiang Zhang, Wang Yao, Jiaping Li and Yu Wang

    Citation: BMC Cancer 2017 17:288

    Content type: Research article

    Published on:

  15. Due to a lack of consensus on adjuvant treatments for pT1N1 gastric cancer, surgeons face a dilemma when deciding treatments for patients with pT1N1 gastric cancer after gastrectomy. The objective of this stud...

    Authors: Hyun Beak Shin, Ji Yeong An, Seung Hyoung Lee, Yoon Young Choi, Jong Won Kim, Soo Sang Sohn and Sung Hoon Noh

    Citation: BMC Cancer 2017 17:287

    Content type: Research article

    Published on:

  16. Ultrasonography (US) is widely used as a standard surveillance tool for patients who are at a high risk of having hepatocellular carcinoma (HCC); however, conventional B-mode US appears to be insufficient in o...

    Authors: Ji Hoon Park, Mi-Suk Park, So Jung Lee, Woo Kyoung Jeong, Jae Young Lee, Min Jung Park, Kyunghwa Han, Chung Mo Nam, Seong Ho Park and Kyoung Ho Lee

    Citation: BMC Cancer 2017 17:279

    Content type: Study protocol

    Published on:

  17. The objective of the study was to reveal through pragmatic MCDA (EVIDEM) the contribution of a broad range of criteria to the value of the orphan drug lenvatinib for radioiodine refractory differentiated thyro...

    Authors: Monika Wagner, Hanane Khoury, Liga Bennetts, Patrizia Berto, Jenifer Ehreth, Xavier Badia and Mireille Goetghebeur

    Citation: BMC Cancer 2017 17:272

    Content type: Research article

    Published on:

  18. There is little information on which pattern should be chosen to perform lymph node dissection for stage I non-small-cell lung cancer. This study aimed to develop a model for predicting lymph node metastasis u...

    Authors: Fei Zhao, Yue Zhou, Peng-Fei Ge, Chen-Jun Huang, Yue Yu, Jun Li, Yun-Gang Sun, Yang-Chun Meng, Jian-Xia Xu, Ting Jiang, Zhi-Xuan Zhang, Jin-Peng Sun and Wei Wang

    Citation: BMC Cancer 2017 17:267

    Content type: Research article

    Published on:

  19. Sentinel node (SN) biopsy (SNB) detects clinically occult metastases of breast cancer and melanoma in 20–30%. Wound infections, seroma and lymph edema occur in up to 10%. Targeted ultrasound (US) of the SN, (w...

    Authors: Charlotte M.C. Oude Ophuis, Lisa B. Koppert, Cécile de Monyé, Carolien H.M. van Deurzen, Senada Koljenović, Alexander C.J. van Akkooi, Cornelis Verhoef and Dirk J. Grünhagen

    Citation: BMC Cancer 2017 17:258

    Content type: Study protocol

    Published on:

    The Erratum to this article has been published in BMC Cancer 2017 17:387

  20. Total mesorectal excision is the standard surgical treatment for mid- and low-rectal cancer. Laparoscopy represents a clear leap forward in the management of rectal cancer patients, offering significant improv...

    Authors: Bernard Lelong, Cécile de Chaisemartin, Helene Meillat, Sandra Cournier, Jean Marie Boher, Dominique Genre, Mehdi Karoui, Jean Jacques Tuech and Jean Robert Delpero

    Citation: BMC Cancer 2017 17:253

    Content type: Study protocol

    Published on:

  21. UroVysion fluorescence in situ hybridization (uFISH) was reported to have superior sensitivity to urine cytology. However uFISH studies are limited by varying definitions of what is considered a positive resul...

    Authors: Hugh J. Lavery, Boriana Zaharieva, Andrew McFaddin, Nyla Heerema and Kamal S. Pohar

    Citation: BMC Cancer 2017 17:247

    Content type: Research article

    Published on:

  22. A new staging system recently proposed by the IGCA has demonstrated a better capacity of stratifying different prognoses for gastric cancer than the 7th edition AJCC staging system (AJCC7). The aim of this stu...

    Authors: Ping Shu, Jing Qin, Kuntang Shen, Weidong Chen, Fenglin Liu, Yong Fang, Xuefei Wang, Hongshan Wang, Zhenbin Shen, Yihong Sun and Xinyu Qin

    Citation: BMC Cancer 2017 17:238

    Content type: Research article

    Published on:

  23. Although the significance of preoperative nutritional status has been investigated, there is no report regarding the relationship of their postoperative changes on outcomes in patients who underwent radical cy...

    Authors: Makito Miyake, Yosuke Morizawa, Shunta Hori, Nagaaki Marugami, Keiji Shimada, Daisuke Gotoh, Yoshihiro Tatsumi, Yasushi Nakai, Takeshi Inoue, Satoshi Anai, Kazumasa Torimoto, Katsuya Aoki, Nobumichi Tanaka and Kiyohide Fujimoto

    Citation: BMC Cancer 2017 17:237

    Content type: Research article

    Published on:

    The Erratum to this article has been published in BMC Cancer 2017 17:353

  24. Negative lymph node (NLN) count has been reported to provide more accurate prognostic information than the N stage alone in patients with rectal cancer (RC). Since preoperative radiotherapy (Pre-RT) can signif...

    Authors: Xinxing Li, Hao Lu, Kai Xu, Haolu Wang, Xiaowen Liang and Zhiqian Hu

    Citation: BMC Cancer 2017 17:227

    Content type: Research article

    Published on:

  25. Follicular thyroid carcinoma (FTC) metastasis to the facial skeleton is exceedingly rare. A case of FTC metastasizing to the mandible is presented and a systematic review of the literature describing thyroid m...

    Authors: Varun V. Varadarajan, Elizabeth K. Pace, Vatsal Patel, Raja Sawhney, Robert J. Amdur and Peter T. Dziegielewski

    Citation: BMC Cancer 2017 17:225

    Content type: Case report

    Published on:

  26. ATP-binding cassette sub-family G member 2 (ABCG2) is a semi-transport protein that plays a major role in multidrug resistance. We aimed to evaluate the prognostic significance of ABCG2 expression in patients wit...

    Authors: Haofei Wang, Fangxiu Luo, Zhe Zhu, Zhaoping Xu, Xin Huang, Renyi Ma, Hongchao He, Yu Zhu, Kun Shao and Juping Zhao

    Citation: BMC Cancer 2017 17:222

    Content type: Research article

    Published on:

  27. Autotransplantation of frozen-thawed ovarian tissue is a method to preserve ovarian function and fertility in patients undergoing gonadotoxic therapy. In oncology patients, the safety cannot yet be guaranteed,...

    Authors: Inge T. A. Peters, Merle A. van der Steen, Bertine W. Huisman, Carina G. J .M. Hilders, Vincent T. H. B. M. Smit, Alexander L. Vahrmeijer, Cornelis F. M. Sier, J. Baptist Trimbos and Peter J. K. Kuppen

    Citation: BMC Cancer 2017 17:206

    Content type: Research article

    Published on:

  28. The aim of this study was to assess and compare the Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST 1.1) and the Choi criteria in evaluating the early response of advanced gastroenteropancreat...

    Authors: Yanji Luo, Jie Chen, Kun Huang, Yuan Lin, Minhu Chen, Ling Xu, Zi-Ping Li and Shi-Ting Feng

    Citation: BMC Cancer 2017 17:154

    Content type: Research article

    Published on:

  29. Chemokine (C–C motif) ligand 17 (CCL17) is a chemokine mainly produced by myeloid dendritic cells. It is a ligand for CC chemokine receptor 4 (CCR4) and CC chemokine receptor 8 (CCR8). The aim of this study wa...

    Authors: Ying Xiong, Li Liu, Yu Xia, Jiajun Wang, Wei Xi, Qi Bai, Yang Qu, Jiejie Xu and Jianming Guo

    Citation: BMC Cancer 2017 17:117

    Content type: Research article

    Published on:

  30. The “TOPical Imiquimod treatment of high-grade Cervical intraepithelial neoplasia” (TOPIC) trial was stopped preliminary, due to lagging inclusions. This study aimed to evaluate the treatment efficacy and clin...

    Authors: M. M. Koeneman, A. J. Kruse, L. F. S. Kooreman, A. zur Hausen, A. H. N. Hopman, S. J. S. Sep, T. Van Gorp, B. F. M. Slangen, H. J. van Beekhuizen, A. J. M. van de Sande, C. G. Gerestein, H. W. Nijman and R. F. P. M. Kruitwagen

    Citation: BMC Cancer 2017 17:110

    Content type: Correspondence

    Published on:

  31. Ongoing improvements in technique and instruments for video-assisted thoracoscopic surgery (VATS) have made minimally-invasive uniportal VATS lobectomy a reality. However, the outcomes of the procedure are sti...

    Authors: Linlin Wang, Dabei Liu, Jibin Lu, Suning Zhang and Xueying Yang

    Citation: BMC Cancer 2017 17:75

    Content type: Research article

    Published on:

  32. Pathological response is an important marker for tumor aggressiveness in patients with esophageal squamous cell carcinoma (ESCC) who receive preoperative chemoradiation followed by esophagectomy. We aim to eva...

    Authors: Cheng-Che Tu, Po-Kuei Hsu, Ling-I Chien, Wan-Chen Liu, Chien-Sheng Huang, Chih-Cheng Hsieh, Han-Shui Hsu and Yu-Chung Wu

    Citation: BMC Cancer 2017 17:62

    Content type: Research article

    Published on:

  33. To assess the accuracy of contrast-enhanced ultrasound (CEUS)-CT/MR image fusion in evaluating the radiofrequency ablative margin (AM) of hepatocellular carcinoma (HCC) based on a custom-made phantom model and...

    Authors: Kai Li, Zhongzhen Su, Erjiao Xu, Qiannan Huang, Qingjing Zeng and Rongqin Zheng

    Citation: BMC Cancer 2017 17:61

    Content type: Research article

    Published on:

  34. Microvascular invasion (MVI) is recognized as a prognostic factor associated with poor outcome in hepatocellular carcinoma (HCC) patients after curative resection. It remains unclear, however, whether MVI can ...

    Authors: Cheng Huang, Xiao-Dong Zhu, Yuan Ji, Guang-Yu Ding, Guo-Ming Shi, Ying-Hao Shen, Jian Zhou, Jia Fan and Hui-Chuan Sun

    Citation: BMC Cancer 2017 17:58

    Content type: Research article

    Published on:

  35. In the early stage esophageal cancer, changes in the mucosa are subtle and pass unnoticed in endoscopic examinations using white light. To increase sensitivity, chromoscopy with Lugol’s solution has been used....

    Authors: Flavio Hiroshi Ananias Morita, Wanderley Marques Bernardo, Edson Ide, Rodrigo Silva Paula Rocha, Julio Cesar Martins Aquino, Mauricio Kazuyoshi Minata, Kendi Yamazaki, Sergio Barbosa Marques, Paulo Sakai and Eduardo Guimarães Hourneaux de Moura

    Citation: BMC Cancer 2017 17:54

    Content type: Research article

    Published on:

  36. Detection of circulating (CTC) or disseminated tumor cells (DTC) has been associated with negative prognosis and outcome in patients with colorectal cancer, though testing for these cells is not yet part of cl...

    Authors: Sebastian Hinz, Alexander Hendricks, Amke Wittig, Clemens Schafmayer, Jürgen Tepel, Holger Kalthoff, Thomas Becker and Christian Röder

    Citation: BMC Cancer 2017 17:53

    Content type: Research article

    Published on:

  37. Long-term term survival in patients with pancreatic neuroendocrine tumors has been reported, even in patients with metastatic disease. Metastases to the spleen are extremely rare, but have been reported from a...

    Authors: Yasunaru Sakuma, Yoshikazu Yasuda, Naohiro Sata, Yoshinori Hosoya, Atsushi Shimizu, Hirofumi Fujii, Daisuke Matsubara, Noriyuki Fukushima, Atsushi Miki, Misato Maeno and Alan Kawarai Lefor

    Citation: BMC Cancer 2017 17:37

    Content type: Case report

    Published on:

  38. Preoperative neoadjuvant therapy for colorectal liver metastases (CRLM) is increasing in use and can lead to chemotherapy-induced damage to sinusoidal integrity, namely sinusoidal obstruction syndrome (SOS). S...

    Authors: Heather L. Stevenson, Mariana M. Prats and Eizaburo Sasatomi

    Citation: BMC Cancer 2017 17:35

    Content type: Research article

    Published on:

  39. The Hangzhou criteria expand the Milan criteria safely and effectively in selecting hepatocellular carcinoma (HCC) candidates for liver transplantation (LT), but some patients exceeding the Milan but fulfillin...

    Authors: Weiliang Xia, Qinghong Ke, Hua Guo, Weilin Wang, Min Zhang, Yan Shen, Jian Wu, Xiao Xu, Sheng Yan, Jun Yu, Mangli Zhang and Shusen Zheng

    Citation: BMC Cancer 2017 17:14

    Content type: Research article

    Published on:

  40. To investigate the impact of biological gender on operative parameters, especially operative time, in laparoscopic partial nephrectomy (LPN) for T1 renal tumor.

    Authors: Hiroki Ito, Kazuhide Makiyama, Takashi Kawahara, Kimito Osaka, Koji Izumi, Yumiko Yokomizo, Noboru Nakaigawa and Masahiro Yao

    Citation: BMC Cancer 2016 16:944

    Content type: Research article

    Published on:

  41. Prognostic factors aid in the stratification and treatment of cancer. This study evaluated the prognostic significance of human epidermal growth factor receptor (HER) family members (HER1–4) expression in pati...

    Authors: Qin Li, Lei Zhang, XiuHong Li, Han Yan, Liuting Yang, Yingying Li, Teng Li, Jing Wang and Bangwei Cao

    Citation: BMC Cancer 2016 16:910

    Content type: Research article

    Published on:

  42. Evaluation of resection margins during cancer surgery can be challenging, often resulting in incomplete tumour removal. Fluorescence-guided surgery (FGS) aims to aid the surgeon to visualize tumours and resect...

    Authors: P. B. A. A. van Driel, M. C. Boonstra, H. A. J. M. Prevoo, M. van de Giessen, T. J. A. Snoeks, Q. R. J. G. Tummers, S. Keereweer, R. A. Cordfunke, A. Fish, J. D. H. van Eendenburg, B. P. F. Lelieveldt, J. Dijkstra, C. J. H. van de Velde, P. J. K. Kuppen, A. L. Vahrmeijer, C. W. G. M. Löwik…

    Citation: BMC Cancer 2016 16:884

    Content type: Research article

    Published on:

  43. Evaluation of lymph node involvement is an important factor in detecting metastasis and deciding whether to perform axillary lymph node dissection (ALND) in breast cancer surgery. As ALND is associated with po...

    Authors: Kelsey M. Kennedy, Lixin Chin, Philip Wijesinghe, Robert A. McLaughlin, Bruce Latham, David D. Sampson, Christobel M. Saunders and Brendan F. Kennedy

    Citation: BMC Cancer 2016 16:874

    Content type: Research article

    Published on:

  44. The purpose of this study is to review our results for pancreatic resection in patients with intraductal papillary mucinous neoplasm (IPMN) with and without associated carcinoma.

    Authors: Katharina Marsoner, Johannes Haybaeck, Dora Csengeri, James Elvis Waha, Jakob Schagerl, Rainer Langeder, Hans Joerg Mischinger and Peter Kornprat

    Citation: BMC Cancer 2016 16:844

    Content type: Research article

    Published on: