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Surgical oncology, cancer imaging, and interventional therapeutics

Section edited by Stephen P. Povoski

This section focuses on clinical research that impacts on the diagnosis and treatment of cancer using surgery, diagnostic imaging, interventional therapeutics, and surgical pathology.

Page 10 of 11

  1. Content type: Research article

    Platelet and blood coagulation abnormalities frequently occur in cancer patients. Fibrinogen is an important hemostatic factor that regulates the hemostatic pathway. Hyperfibrinogenemia is increasing recognize...

    Authors: Xuefeng Yu, Fulan Hu, Qiang Yao, Chunfeng Li, Hongfeng Zhang and Yingwei Xue

    Citation: BMC Cancer 2016 16:480

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  2. Content type: Research article

    The clinicopathological features and prognosis of gastric cancer in young patients are both limited and controversial. Therefore, the aim of this study was to define the clinicopathological features and progno...

    Authors: Shushang Liu, Fan Feng, Guanghui Xu, Zhen Liu, Yangzi Tian, Man Guo, Xiao Lian, Lei Cai, Daiming Fan and Hongwei Zhang

    Citation: BMC Cancer 2016 16:478

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  3. Content type: Research article

    Mammography and ultrasound are the gold standard imaging techniques for preoperative assessment and for monitoring the efficacy of neoadjuvant chemotherapy in breast cancer. Maximum accuracy in predicting path...

    Authors: Roland Gregor Stein, Daniel Wollschläger, Rolf Kreienberg, Wolfgang Janni, Manfred Wischnewsky, Joachim Diessner, Tanja Stüber, Catharina Bartmann, Mathias Krockenberger, Jörg Wischhusen, Achim Wöckel, Maria Blettner and Lukas Schwentner

    Citation: BMC Cancer 2016 16:459

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  4. Content type: Research article

    Diagnosing breast cancer during the early stage may be helpful for decreasing cancer-related mortality. In Western developed countries, mammographies have been the gold standard for breast cancer detection. Ho...

    Authors: Xiuyan Yu, Guoming Hu, Zhigang Zhang, Fuming Qiu, Xuan Shao, Xiaochen Wang, Hongwei Zhan, Yiding Chen, Yongchuan Deng and Jian Huang

    Citation: BMC Cancer 2016 16:450

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  5. Content type: Research article

    Our aim was to investigate the influence of FTS on human cellular and humoral immunity using a randomized controlled clinical study in esophageal cancer patients.

    Authors: Lantao Chen, Lixin Sun, Yaoguo Lang, Jun Wu, Lei Yao, Jinfeng Ning, Jinfeng Zhang and Shidong Xu

    Citation: BMC Cancer 2016 16:449

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  6. Content type: Case report

    Intraocular iris rhabdomyosarcoma is extremely rare, and in the 3 cases reported to date occurred as the primary site of tumour growth. We report a case of rhabdomyosarcoma of the foot metastasizing to the iris.

    Authors: Ido Didi Fabian, G. Darius Hildebrand, Shaun Wilson, Tina Foord and Mandeep S. Sagoo

    Citation: BMC Cancer 2016 16:447

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  7. Content type: Research article

    Multiple myeloma osteolytic disease affecting the spine results in vertebral compression fractures. These are painful, result in kyphosis, and impact respiratory function and quality of life. We explore the im...

    Authors: Karan Malhotra, Joseph S. Butler, Hai Ming Yu, Susanne Selvadurai, Shirley D’Sa, Neil Rabin, Charalampia Kyriakou, Kwee Yong and Sean Molloy

    Citation: BMC Cancer 2016 16:444

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  8. Content type: Research article

    Recent large trials have shown the survival benefits of 10-year use of tamoxifen by reducing late recurrence compared with 5-year therapy in estrogen receptor(ER)-positive breast cancer. We tried to identify c...

    Authors: Eun-Shin Lee, Wonshik Han, Min Kyoon Kim, Jongjin Kim, Tae-kyung Yoo, Moo Hyun Lee, Kyung Hun Lee, Tae Yong Kim, Hyeong-Gon Moon, Seock-Ah Im, Dong-Young Noh and Eun Sook Lee

    Citation: BMC Cancer 2016 16:430

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  9. Content type: Research article

    Several staging systems have been developed to evaluate patients with hepatocellular carcinoma (HCC), including the China Staging System (CS), the American Joint Committee on Cancer (AJCC) tumor-node-metastasi...

    Authors: Lihui Su, Tao Zhou, Zongli Zhang, Xiuguo Zhang, Xuting Zhi, Caixia Li, Qingliang Wang, Chongqi Jia, Wenna Shi, Yanqiu Yue, Yanjing Gao and Baoquan Cheng

    Citation: BMC Cancer 2016 16:424

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  10. Content type: Research article

    Detecting superficial head and neck squamous cell carcinoma (HNSCC) by endoscopy is challenging because of limited morphological hallmarks, and iodine cannot be applied to head and neck lesions due to severe m...

    Authors: Takeshi Mizushima, Shunsuke Ohnishi, Yuichi Shimizu, Yutaka Hatanaka, Kanako C. Hatanaka, Hidetaka Hosono, Yoshimasa Kubota, Mitsuteru Natsuizaka, Mako Kamiya, Shouko Ono, Akihiro Homma, Mototsugu Kato, Naoya Sakamoto and Yasuteru Urano

    Citation: BMC Cancer 2016 16:411

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  11. Content type: Research article

    Prostate cancer (PCa) is the most common non-skin cancer in USA and the second leading cause of cancer death in Western Countries. Despite the high mortality associated with PCa, the only established risk fact...

    Authors: Cosimo De Nunzio, Giuseppe Simone, Aldo Brassetti, Riccardo Mastroianni, Devis Collura, Giovanni Muto, Michele Gallucci and Andrea Tubaro

    Citation: BMC Cancer 2016 16:407

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  12. Content type: Research article

    Transanal total mesorectal excision (taTME) is an emerging surgical technique for rectal cancer. However, the oncological and perioperative outcomes are controversial when compared with conventional laparoscop...

    Authors: Bin Ma, Peng Gao, Yongxi Song, Cong Zhang, Changwang Zhang, Longyi Wang, Hongpeng Liu and Zhenning Wang

    Citation: BMC Cancer 2016 16:380

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  13. Content type: Study protocol

    Along with the marked increase in early gastric cancer (EGC) in the Eastern countries, there has been an effort to adopt the sentinel node concept in EGC to preserve gastric function and reduce the occurrence ...

    Authors: Ji Yeon Park, Young-Woo Kim, Keun Won Ryu, Byung-Ho Nam, Young Joon Lee, Sang Ho Jeong, Ji-Ho Park, Hoon Hur, Sang-Uk Han, Jae Seok Min, Ji Yeong An, Woo Jin Hyung, Gyu Seok Cho, Gui Ae Jeong, Oh Jeong, Young Kyu Park…

    Citation: BMC Cancer 2016 16:340

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  14. Content type: Study protocol

    Urinary, sexual and anorectal sequelae are frequent after rectal cancer surgery and were found to be related to intraoperative neurogenic impairment. Neuromonitoring methods have been developed to identify and...

    Authors: D. W. Kauff, K Kronfeld, S Gorbulev, D Wachtlin, H Lang and W Kneist

    Citation: BMC Cancer 2016 16:323

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  15. Content type: Study protocol

    Current surgical and ablative treatment options for prostate cancer (PCa) may result in a high incidence of (temporary) incontinence, erectile dysfunction and/or bowel damage. These side effects are due to pro...

    Authors: Matthijs J. V. Scheltema, Willemien van den Bos, Daniel M. de Bruin, Hessel Wijkstra, M. Pilar Laguna, Theo M. de Reijke and Jean JMCH de la Rosette

    Citation: BMC Cancer 2016 16:299

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  16. Content type: Research article

    To assess whether intraoperative use of contrast-enhanced ultrasound (CEUS)-CT/MR image fusion can accurately evaluate ablative margin (AM) and guide supplementary ablation to improve AM after hepatocellular c...

    Authors: Kai Li, Zhong-Zhen Su, Er-Jiao Xu, Jin-Xiu Ju, Xiao-Chun Meng and Rong-Qin Zheng

    Citation: BMC Cancer 2016 16:277

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  17. Content type: Study protocol

    Among patients with rectal cancer, 5–10 % have a primary rectal cancer beyond the total mesorectal excision plane (PRC-bTME) and 10 % recur locally following primary surgery (LRRC). In both cases, patients ‘ca...

    Authors: Quentin Denost, Florence Saillour, Lindy Masya, Helene Maillou Martinaud, Stephanie Guillon, Marion Kret, Eric Rullier, Bruno Quintard and Michael Solomon

    Citation: BMC Cancer 2016 16:262

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  18. Content type: Research article

    The information surgeons impart to patients and information patients want about surgery for cancer is important but rarely examined. This study explored information provided by surgeons and patient preferences...

    Authors: Angus G. K. McNair, F MacKichan, J. L. Donovan, S. T. Brookes, K. N. L. Avery, S. M. Griffin, T. Crosby and J. M. Blazeby

    Citation: BMC Cancer 2016 16:258

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  19. Content type: Research article

    Advanced glycation end products (AGEs) and their receptor RAGE emerge as important pathogenic contributors in colorectal carcinogenesis. However, their relationship to the detoxification enzyme Glyoxalase (GLO...

    Authors: Stratigoula Sakellariou, Paraskevi Fragkou, Georgia Levidou, Antonios N. Gargalionis, Christina Piperi, Georgia Dalagiorgou, Christos Adamopoulos, Angelica Saetta, George Agrogiannis, Irini Theohari, Stavros Sougioultzis, Panagiota Tsioli, Ioannis Karavokyros, Nikolaos Tsavaris, Ioannis D. Kostakis, Adamantia Zizi-Serbetzoglou…

    Citation: BMC Cancer 2016 16:174

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  20. Content type: Research article

    It is generally believed that patients with Hürthle cell thyroid carcinoma (HCTC) have a poor prognosis. Furthermore, distant metastases represent the most frequent cause of thyroid cancer-related death of pat...

    Authors: Nikola Besic, Andreja Schwarzbartl-Pevec, Barbara Vidergar-Kralj, Tea Crnic, Barbara Gazic and Maja Marolt Music

    Citation: BMC Cancer 2016 16:162

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  21. Content type: Research article

    Combined hepatocellular-cholangiocarcinoma (cHCC-CC) is an uncommon primary liver malignancy and little known about the clinical and imaging characteristics of cHCC-CC. We aim to define the demographics, imagi...

    Authors: Rui Li, Dan Yang, Chun-Lin Tang, Ping Cai, Kuan-sheng Ma, Shi-Yi Ding, Xiao-Hang Zhang, De-Yu Guo and Xiao-Chu Yan

    Citation: BMC Cancer 2016 16:158

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  22. Content type: Research article

    Evaluation of lymph node (LN) status is an important factor for detecting metastasis and thereby staging breast cancer. Currently utilized clinical techniques involve the surgical disruption and resection of l...

    Authors: Ryan M. Nolan, Steven G. Adie, Marina Marjanovic, Eric J. Chaney, Fredrick A. South, Guillermo L. Monroy, Nathan D. Shemonski, Sarah J. Erickson-Bhatt, Ryan L. Shelton, Andrew J. Bower, Douglas G. Simpson, Kimberly A. Cradock, Z. George Liu, Partha S. Ray and Stephen A. Boppart

    Citation: BMC Cancer 2016 16:144

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  23. Content type: Research article

    The occurrence and development of hepatocellular carcinoma (HCC) depends largely on such non-tumor factors as inflammatory condition, immune state, viral infection and liver fibrosis. Various inflammation-base...

    Authors: Fei Ji, Yao Liang, Shun-Jun Fu, Zhi-Yong Guo, Man Shu, Shun-Li Shen, Shao-Qiang Li, Bao-Gang Peng, Li-Jian Liang and Yun-Peng Hua

    Citation: BMC Cancer 2016 16:137

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  24. Content type: Research article

    The bone scan index (BSI) using a computer-aided diagnosis system for bone scans is expected to be an objective and quantitative clinical tool for evaluating bone metastatic prostate cancer. This study aimed t...

    Authors: Yasuhide Miyoshi, Shuko Yoneyama, Takashi Kawahara, Yusuke Hattori, Jun-ichi Teranishi, Keiichi Kondo, Masatoshi Moriyama, Shigeo Takebayashi, Yumiko Yokomizo, Masahiro Yao, Hiroji Uemura and Kazumi Noguchi

    Citation: BMC Cancer 2016 16:128

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  25. Content type: Research article

    Oesophagogastric adenocarcinoma (OGA) has a poor prognosis, even for patients with operable disease. However, the optimal surveillance strategy following surgery is unknown.

    Authors: Sing Yu Moorcraft, Elisa Fontana, David Cunningham, Clare Peckitt, Tom Waddell, Elizabeth C. Smyth, William Allum, Jeremy Thompson, Sheela Rao, David Watkins, Naureen Starling and Ian Chau

    Citation: BMC Cancer 2016 16:112

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  26. Content type: Research article

    The bone scan index (BSI), which is obtained using a computer-aided bone scan evaluation system, is anticipated to become an objective and quantitative clinical tool for evaluating bone metastases in prostate ...

    Authors: Koichi Uemura, Yasuhide Miyoshi, Takashi Kawahara, Shuko Yoneyama, Yusuke Hattori, Jun-ichi Teranishi, Keiichi Kondo, Masatoshi Moriyama, Shigeo Takebayashi, Yumiko Yokomizo, Masahiro Yao, Hiroji Uemura and Kazumi Noguchi

    Citation: BMC Cancer 2016 16:109

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  27. Content type: Research article

    The combination of blue dye and radioisotope is most widely used to identify sentinel lymph nodes (SLNs) in patients with breast cancer. However, some individual studies suggested that dual tracers did not hav...

    Authors: Pei-Sheng He, Feng Li, Guan-Hua Li, Can Guo and Tian-Jin Chen

    Citation: BMC Cancer 2016 16:107

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  28. Content type: Research article

    Lymph node (LN) involvement represents the strongest prognostic factor in colon cancer patients. The objective of this prospective study was to assess the prognostic impact of isolated tumor cells (ITC, define...

    Authors: B. Weixler, R. Warschkow, U. Güller, A. Zettl, U. von Holzen, B. M. Schmied and M. Zuber

    Citation: BMC Cancer 2016 16:106

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  29. Content type: Research article

    Early gastric cancer is defined as a lesion confined to the mucosa or submucosa, regardless of the size or lymph node metastasis. Treatment methods include endoscopic mucosal resection or endoscopic submucosal...

    Authors: Zhixue Zheng, Yinan Zhang, Lianhai Zhang, Ziyu Li, Xiaojiang Wu, Yiqiang Liu, Zhaode Bu and Jiafu Ji

    Citation: BMC Cancer 2016 16:92

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  30. Content type: Research article

    Little is known about the safety of the anti-VEGF antibody bevacizumab in patients undergoing resection for colorectal liver metastases (CLM). This meta-analysis evaluates the impact of bevacizumab on parenchy...

    Authors: Andreas M. Volk, Johannes Fritzmann, Christoph Reissfelder, Georg F. Weber, Jürgen Weitz and Nuh N. Rahbari

    Citation: BMC Cancer 2016 16:84

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  31. Content type: Research article

    Intravoxel incoherent motion (IVIM) MR imaging has been applied in researches of various diseases, however its potential in cervical cancer patients has not been fully explored. The purpose of this study was t...

    Authors: Li Zhu, Lijing Zhu, Hua Shi, Huanhuan Wang, Jing Yan, Baorui Liu, Weibo Chen, Jian He, Zhengyang Zhou, Xiaofeng Yang and Tian Liu

    Citation: BMC Cancer 2016 16:79

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  32. Content type: Research article

    Intravenous leiomyomatosis (IVL) extending to inferior vena cava and heart is one of the most challenging conditions for surgical treatment. We explored the use of computerized tomography angiography (CTA) in ...

    Authors: Ting Gui, Qiuhong Qian, Dongyan Cao, Jiaxin Yang, Ping Peng and Keng Shen

    Citation: BMC Cancer 2016 16:73

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  33. Content type: Research article

    Aberrant TGF-β1 signaling is suggested to be involved in gastric carcinogenesis. However, the role of TGF-β1 in intestinal-type [i-GC] and diffuse-type [d-GC] gastric cancer remains largely unknown. In this st...

    Authors: Kyung Ho Pak, Dong Hoon Kim, Hyunki Kim, Do Hyung Lee and Jae-Ho Cheong

    Citation: BMC Cancer 2016 16:60

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    The Erratum to this article has been published in BMC Cancer 2016 16:99

  34. Content type: Research article

    To correlate parameters of Ultrasonography-guided Diffuse optical tomography (US-DOT) with pharmacokinetic features of Dynamic contrast-enhanced (DCE)-MRI and pathologic markers of breast cancer.

    Authors: Min Jung Kim, Min-Ying Su, Hon J Yu, Jeon-Hor Chen, Eun-Kyung Kim, Hee Jung Moon and Ji Soo Choi

    Citation: BMC Cancer 2016 16:50

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  35. Content type: Research article

    Utilisation of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) and guide sheath (EBUS-GS) for diagnosis and staging of lung cancer is gaining popularity, however, its impact on cli...

    Authors: Neli S. Slavova-Azmanova, Catalina Lizama, Claire E. Johnson, Herbert P. Ludewick, Leanne Lester, Shanka Karunarathne and Martin Phillips

    Citation: BMC Cancer 2016 16:44

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  36. Content type: Research article

    Over 20 % of ovarian cancer patients have preoperative thrombocytosis or hyperfibrinogenemia. We aimed to demonstrate the clinical and prognostic significance of thrombocytosis and hyperfibrinogenemia in high-...

    Authors: Zheng Feng, Hao Wen, Rui Bi, Yachen Duan, Wentao Yang and Xiaohua Wu

    Citation: BMC Cancer 2016 16:43

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  37. Content type: Research article

    Preoperative chemotherapy (PCT) and chemoradiotherapy (PCRT) showed promising results for gastric cancers. However, the influence of preoperative adverse events (AEs) on postoperative complications remains unk...

    Authors: Shuang-Xi Li, Sang Hyuk Seo, Yoon Young Choi, Masatoshi Nakagawa, Ji Yeong An, Hyoung-Il Kim, Jae-Ho Cheong, Woo Jin Hyung and Sung Hoon Noh

    Citation: BMC Cancer 2016 16:29

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  38. Content type: Research article

    FoxC2 is an epithelial–mesenchymal transition (EMT) regulator which induces metastasis. The purpose of this study is to assess the prognostic value of FoxC2 expression in non-small cell lung cancer (NSCLC), al...

    Authors: Wei Jiang, Hong Fan, Cheng Qian, Jianyong Ding, Qun Wang and Xuguang Pang

    Citation: BMC Cancer 2016 16:16

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  39. Content type: Study protocol

    For decades, planar bone scintigraphy has been the standard practice for detection of bone metastases in prostate cancer and has been endorsed by recent oncology/urology guidelines. It is a sensitive method wi...

    Authors: Randi F. Fonager, Helle D. Zacho, Niels C. Langkilde and Lars J. Petersen

    Citation: BMC Cancer 2016 16:10

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  40. Content type: Case report

    Intravenous leiomyomas are a rare variant of uterine leiomyoma. Although histologically benign, these tumors are associated with a poor prognosis due to propensity for metastasis, high recurrence rate, difficu...

    Authors: Ying Zhang, Leslie H. Clark, Xiugui Sheng and Chunxiao Zhou

    Citation: BMC Cancer 2016 16:6

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  41. Content type: Case report

    The objective of the study was to explore the clinical expression, radiological and pathological features, differential diagnosis, and biological behavior of a clear cell myomelanocytic tumor. In a case involv...

    Authors: Zu-Sen Wang, Lin Xu, Lin Ma, Meng-Qi Song, Li-Qun Wu and Xuan Zhou

    Citation: BMC Cancer 2015 15:1004

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  42. Content type: Research article

    Use of FDG-PET/CT for staging and restaging of lymphoma patients is widely incorporated into current practice guidelines. Our aim was to prospectively evaluate the diagnostic performance of FDG-PET/MRI and WB-...

    Authors: Ken Herrmann, Marcelo Queiroz, Martin W. Huellner, Felipe de Galiza Barbosa, Andreas Buck, Niklaus Schaefer, Paul Stolzman and Patrick Veit-Haibach

    Citation: BMC Cancer 2015 15:1002

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  43. Content type: Research article

    The study was to investigate whether 18F-fluorodeoxyglucose (18F-FDG) uptake, analyzed by positron emission tomography (PET), can be used preoperatively to predict survival in Chinese patients with colorectal car...

    Authors: Debing Shi, Guoxiang Cai, Junjie Peng, Dawei Li, Xinxiang Li, Ye Xu and Sanjun Cai

    Citation: BMC Cancer 2015 15:991

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  44. Content type: Study protocol

    Selected patients with peritoneal carcinomatosis (PC) from colorectal cancer (CRC) benefit from cytoreductive surgery (CRS) combined with intraperitoneal chemoperfusion (IPC). However, even after optimal cytor...

    Authors: Wouter Willaert, Kurt Van Der Speeten, Gabriel Liberale and Wim Ceelen

    Citation: BMC Cancer 2015 15:980

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  45. Content type: Research article

    The relationship between pathological factors and lymph node metastasis of pathological stage early gastric cancer has been extensively investigated. By contrast, the relationship between preoperative factors ...

    Authors: Masatoshi Nakagawa, Yoon Young Choi, Ji Yeong An, Hyunsoo Chung, Sang Hyuk Seo, Hyun Beak Shin, Hui-Jae Bang, Shuangxi Li, Hyung-Il Kim, Jae-Ho Cheong, Woo Jin Hyung and Sung Hoon Noh

    Citation: BMC Cancer 2015 15:943

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  46. Content type: Research article

    With the remarkable improvements in ultrasound equipment, transabdominal ultrasound after oral administration of an echoic cellulose-based gastric ultrasound contrast agent (TUS-OCCA) has recently been suggest...

    Authors: Zhijun Liu, Jintao Guo, Shupeng Wang, Ying Zhao, Jing Li, Weidong Ren, Shaoshan Tang, Limei Xie, Ying Huang, Siyu Sun and Liping Huang

    Citation: BMC Cancer 2015 15:932

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  47. Content type: Study protocol

    Current evidence supports a diverting stoma in patients undergoing low anterior resection with total mesorectal excision for rectal cancer as it reduces clinical severity of anastomotic leakage. However, relev...

    Authors: Flavius Sandra-Petrescu, Florian Herrle, Axel Hinke, Inga Rossion, Heiko Suelberg, Stefan Post, Ralf-Dieter Hofheinz and Peter Kienle

    Citation: BMC Cancer 2015 15:923

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