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Surgical oncology, cancer imaging, and interventional therapeutics

Section edited by Stephen P. Povoski

This section focuses on clinical research that impacts on the diagnosis and treatment of cancer using surgery, diagnostic imaging, interventional therapeutics, and surgical pathology.

Page 1 of 11

  1. The aim of this study was to assess the agreement rate between intraoperative evaluation (IOE) and final diagnosis (FD) in a series of surgically resected endometrial carcinoma (EC), with a preoperative ambigu...

    Authors: A. Santoro, A. Piermattei, F. Inzani, G. Angelico, M. Valente, D. Arciuolo, S. Spadola, M. Martini, F. Fanfani, A. Fagotti, V. Gallotta, G. Scambia and G. F. Zannoni

    Citation: BMC Cancer 2019 19:1096

    Content type: Research article

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  2. We designed a retrospective study to compare prognostic outcomes based on whether or not surgical resection was performed in elderly patients aged(≥75 years) with resectable pancreatic cancer.

    Authors: Hyeong Min Park, Sang-Jae Park, Sung-Sik Han and Seoung Hoon Kim

    Citation: BMC Cancer 2019 19:1090

    Content type: Research article

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  3. High perioperative morbidity, mortality, and uncertain outcome of surgery in octogenarians with proximal gastric carcinoma (PGC) pose a dilemma for both patients and physicians. We aim to evaluate the risks an...

    Authors: Xuefei Wang, Junjie Zhao, Mark Fairweather, Tingsong Yang, Yihong Sun and Jiping Wang

    Citation: BMC Cancer 2019 19:1079

    Content type: Research article

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  4. Increase of circulating tumor cells (CTCs) has been found after surgery for various carcinomas but not confirmed for breast cancer, and whether endoscopic surgery confers identical effect to CTCs as open surge...

    Authors: Shichao Li, Wenting Yan, Xinhua Yang, Li Chen, Linjun Fan, Haoxi Liu, Kun Liu, Yi Zhang and Jun Jiang

    Citation: BMC Cancer 2019 19:1070

    Content type: Research article

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  5. The computed tomography (CT) features of small solid lung cancers and their changing regularity as they grow have not been well studied. The purpose of this study was to analyze the CT features of solid lung c...

    Authors: Zhi-gang Chu, Yan Zhang, Wang-jia Li, Qi Li, Yi-neng Zheng and Fa-jin Lv

    Citation: BMC Cancer 2019 19:1060

    Content type: Research article

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  6. Most lymph node metastasis (LNM) models for early gastric cancer (EGC) include lymphovascular invasion (LVI) as a predictor. However, LVI must be confirmed by postoperative pathology. In this study, we aimed t...

    Authors: Jian-Xian Lin, Zu-Kai Wang, Wei Wang, Jacopo Desiderio, Jian-Wei Xie, Jia-Bin Wang, Jun Lu, Qi-Yue Chen, Long-Long Cao, Mi Lin, Ru-Hong Tu, Chao-Hui Zheng, Ping Li, Amilcare Parisi, Zhi-Wei Zhou and Chang-Ming Huang

    Citation: BMC Cancer 2019 19:1048

    Content type: Research article

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  7. The application of laparoscopic liver resection (LLR) has expanded rapidly in recent decades. Although multiple authors have reported LLR shows improved safety and efficacy in treating hepatocellular carcinoma...

    Authors: Zi-Yu Wang, Qing-Lian Chen, Ling-Ling Sun, Shu-Ping He, Xiao-Fen Luo, Li-Shuang Huang, Jun-Hai Huang, Cheng-Ming Xiong and Chong Zhong

    Citation: BMC Cancer 2019 19:1047

    Content type: Research article

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  8. Assessment of preoperative general condition to predict postoperative outcomes is important, particularly in older patients who typically suffer from various comorbidities and exhibit impaired functional statu...

    Authors: Yuka Ahiko, Dai Shida, Tomoko Horie, Taro Tanabe, Yasuyuki Takamizawa, Ryohei Sakamoto, Konosuke Moritani, Shunsuke Tsukamoto and Yukihide Kanemitsu

    Citation: BMC Cancer 2019 19:946

    Content type: Research article

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  9. Radiological imaging plays a central role in the diagnosis of breast cancer (BC). Some studies suggest MRI techniques like diffusion weighted imaging (DWI) may provide further prognostic value by discriminatin...

    Authors: Alexey Surov, Yun-Woo Chang, Lihua Li, Laura Martincich, Savannah C. Partridge, Jin You Kim and Andreas Wienke

    Citation: BMC Cancer 2019 19:1043

    Content type: Research article

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  10. The ultimate goal of locoregional therapy (LRT) to the liver is to induce total tumor necrosis. Trans-arterial chemoembolization (TACE) is the mainstay bridging therapy for patients with hepatocellular carcino...

    Authors: Wei Zhang, An-Hui Xu, Wei Wang, Yan-Hui Wu, Qian-Ling Sun and Chang Shu

    Citation: BMC Cancer 2019 19:1041

    Content type: Research article

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  11. Many data suggest that patients with low rectal adenocarcinoma who achieved ypT0N0 status have improved survival and disease-free survival (DFS) compared to all other stages however only few data are available...

    Authors: Amine Souadka, Mohammed Anass Majbar, Amine Benkabbou, Badr Serji, Tarik Souiki, Sidi Mohammed Bouchentouf, Mourad Abid, Basma El Khannousi, Tijani El Harroudi, Hadj Omar El Malki, Mohammed Raiss, Lahsen Ifrine, Khalid Mazaz, Aziz Zentar, Raouf Mohsine, Abdelilah Souadka…

    Citation: BMC Cancer 2019 19:1008

    Content type: Research article

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  12. Amputation is the standard of care even for early-stage subungual melanomas (SUMs), known as nail apparatus melanoma, because the nail bed and nail matrix are close to the distal phalanx. However, a recent stu...

    Authors: Kiyo Tanaka, Yasuhiro Nakamura, Tomonori Mizutani, Taro Shibata, Arata Tsutsumida, Haruhiko Fukuda, Shigeto Matsushita, Megumi Aoki, Kenjiro Namikawa, Shuichi Ohe, Satoshi Fukushima and Naoya Yamazaki

    Citation: BMC Cancer 2019 19:1002

    Content type: Study protocol

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  13. Overexpression of epidermal growth factor receptor (EGFR) has been established as a valid therapeutic target of non-small cell lung cancer (NSCLC). However, the clinical benefit of cetuximab as an EGFR-targeti...

    Authors: Aiko Yamaguchi, Arifudin Achmad, Hirofumi Hanaoka, Yusri Dwi Heryanto, Anu Bhattarai, Ratianto, Erdene Khongorzul, Rini Shintawati, A. Adhipatria P. Kartamihardja, Ayaka Kanai, Yumi Sugo, Noriko S. Ishioka, Tetsuya Higuchi and Yoshito Tsushima

    Citation: BMC Cancer 2019 19:1000

    Content type: Research article

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  14. To compare the value of two dynamic contrast-enhanced Magnetic Resonance Images (DCE-MRI) reconstruction approaches, namely golden-angle radial sparse parallel (GRASP) and view-sharing with golden-angle radial...

    Authors: Yanan Lu, Ling Ma, Jianjun Qin, Zhaoqi Wang, Jia Guo, Yan Zhao, Hongkai Zhang, Xu Yan, Hui Liu, Hailiang Li, Ihab R. Kamel and Jinrong Qu

    Citation: BMC Cancer 2019 19:999

    Content type: Research article

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  15. Limited evidence is available regarding the dissemination of tumor tissues due to compression during massage therapy, a routine procedure in patients with various symptoms in Asian countries.

    Authors: Shinji Miwa, Michi Kamei, Satoru Yoshida, Satoshi Yamada, Hisaki Aiba, Hiroyuki Tsuchiya and Takanobu Otsuka

    Citation: BMC Cancer 2019 19:993

    Content type: Case report

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  16. Laparoscopic surgery, fast-track perioperative treatment and XELOX chemotherapy are effective strategies for shortening the duration of hospital stay for cancer patients. This trial aimed to clarify the safety...

    Authors: Jun Li, Xiang-Xing Kong, Jiao-Jiao Zhou, Yong-Mao Song, Xue-Feng Huang, Gen-Hai Li, Xiao-Jiang Ying, Xiao-Yu Dai, Min Lu, Kai Jiang, Dong-Liang Fu, Xin-Lin Li, Jin-Jie He, Jian-Wei Wang, Li-Feng Sun, Dong Xu…

    Citation: BMC Cancer 2019 19:988

    Content type: Research article

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  17. Breast cancer related lymphoedema (BCRL) is a common side effect of cancer treatment. Recently indocyanine green (ICG) fluorescent lymphography has become a popular method for imaging the lymphatics, however t...

    Authors: Hiroo Suami, Asha Heydon-White, Helen Mackie, Sharon Czerniec, Louise Koelmeyer and John Boyages

    Citation: BMC Cancer 2019 19:985

    Content type: Technical advance

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  18. To determine the safety and efficacy of transarterial chemoembolization (TACE) combined with radiofrequency ablation (hereafter, TACE-RFA) in treating Barcelona Clinic Liver Cancer (BCLC) Stage A or B (hereaft...

    Authors: Yanqiao Ren, Yanyan Cao, Hong Ma, Xuefeng Kan, Chen Zhou, Jiacheng Liu, Qin Shi, Gansheng Feng, Bin Xiong and Chuansheng Zheng

    Citation: BMC Cancer 2019 19:983

    Content type: Research article

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  19. To our knowledge, there are no studies to systematically compare the detailed clinical significance between curatively resected pancreatic head (ph) and body-tail (pbt) ductal adenocarcinoma based on the new 8...

    Authors: Weiwei Sheng, Ming Dong, Guosen Wang, Xiaoyang Shi, Wei Gao, Kewei Wang, He Song, Gang Shi and Xiaodong Tan

    Citation: BMC Cancer 2019 19:981

    Content type: Research article

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  20. One critical step in the therapy of patients with localized pancreatic cancer is the determination of local resectability. The decision between primary surgery versus upfront local or systemic cancer therapy s...

    Authors: U. A. Wittel, D. Lubgan, M. Ghadimi, O. Belyaev, W. Uhl, W. O. Bechstein, R. Grützmann, W. M. Hohenberger, A. Schmid, L. Jacobasch, R. S. Croner, A. Reinacher-Schick, U. T. Hopt, A. Pirkl, H. Oettle, R. Fietkau…

    Citation: BMC Cancer 2019 19:979

    Content type: Research article

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  21. The aim of this study is to present and evaluate surgical resection and reconstructive techniques using autologous femoral head bone-grafting in treating partial acetabular defects arising from primary pelvic ...

    Authors: Wei Sun, Pengfei Zan, Xiaojun Ma, Yingqi Hua, Jiakang Shen and Zhengdong Cai

    Citation: BMC Cancer 2019 19:969

    Content type: Research article

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  22. Lymphoma and dysplasia are rare complications of long-standing Crohn’s disease. We report an exceptional case of a synchronous intestinal marginal zone B-cell lymphoma (MALT lymphoma) and colonic adenoma in a ...

    Authors: Amal Bennani, Ghizlane Kharrasse, Miry Achraf, Khanoussi Wafa, Ismaili Zahi, Kamaoui Imane and Bouziane Mohamed

    Citation: BMC Cancer 2019 19:966

    Content type: Case report

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  23. 99mTc-Rituximab is a new specific radiopharmaceutical that binds to the CD20 receptor which is highly expressed on the surface of B cells. We conducted a study in which 99mTc-Rituximab was compared with filtered

    Authors: Jing-Jie Zhang, Wan-Chun Zhang, Cai-Xia An, Xiao-Min Li and Le Ma

    Citation: BMC Cancer 2019 19:956

    Content type: Research article

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  24. Lymph-node (LN) metastasis is an important prognostic factor in resected pancreatic cancer. In this study, the prognostic value of American Joint Committee on Cancer (AJCC) 8th edition N stage, lymph-node rati...

    Authors: Min Su You, Sang Hyub Lee, Young Hoon Choi, Bang-sup Shin, Woo Hyun Paik, Ji Kon Ryu, Yong-Tae Kim, Dong Kee Jang, Jun Kyu Lee, Wooil Kwon, Jin-Young Jang and Sun-Whe Kim

    Citation: BMC Cancer 2019 19:952

    Content type: Research article

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  25. Biliary rhabdomyosarcoma (RMS) is the most common biliary tumor in children. The management of affected patients contains unique challenges because of the rarity of this tumor entity and its critical location ...

    Authors: Cristian Urla, Steven W. Warmann, Monika Sparber-Sauer, Andreas Schuck, Ivo Leuschner, Thomas Klingebiel, Gunnar Blumenstock, Guido Seitz, Ewa Koscielniak and Jörg Fuchs

    Citation: BMC Cancer 2019 19:945

    Content type: Research article

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  26. This preliminary study aimed to examine the feasibility of sentinel lymph node biopsy (SLNB) using contrast-enhanced ultrasound (CEUS) vs. indocyanine green fluorescence (ICG), combined with blue dye in patien...

    Authors: Yidong Zhou, Yan Li, Feng Mao, Jing Zhang, Qingli Zhu, Songjie Shen, Yan Lin, Xiaohui Zhang, He Liu, Mengsu Xiao, Yuxin Jiang and Qiang Sun

    Citation: BMC Cancer 2019 19:939

    Content type: Research article

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  27. To investigate the implications of prophylactic intraoperative Hyperthermic Intraperitoneal Chemotherapy (HIPEC) with D2 radical gastrectomy for locally advanced Gastric Cancer (AGC) in a randomized case contr...

    Authors: Maneesh Kumarsing Beeharry, Zheng-Lun Zhu, Wen-Tao Liu, Xue-Xin Yao, Min Yan and Zheng-Gang Zhu

    Citation: BMC Cancer 2019 19:932

    Content type: Research article

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  28. Preoperative 5-FU-based chemoradiation is currently a standard treatment for advanced rectal cancer, particularly in Western countries. Although it reduced the local recurrence, it could not necessarily improv...

    Authors: Tsunekazu Mizushima, Masataka Ikeda, Takeshi Kato, Atsuyo Ikeda, Junichi Nishimura, Taishi Hata, Chu Matsuda, Taroh Satoh, Masaki Mori and Yuichiro Doki

    Citation: BMC Cancer 2019 19:929

    Content type: Research article

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  29. Pancreatic adenocarcinoma is a high-mortality neoplasm with a documented 5-years-overall survival around 5%. In the last decades, a real breakthrough in the treatment of the disease has not been achieved. Here...

    Authors: Viviana Vitolo, Lorenzo Cobianchi, Silvia Brugnatelli, Amelia Barcellini, Andrea Peloso, Angelica Facoetti, Alessandro Vanoli, Sara Delfanti, Lorenzo Preda, Silvia Molinelli, Catherine Klersy, Piero Fossati, Roberto Orecchia and Francesca Valvo

    Citation: BMC Cancer 2019 19:922

    Content type: Study protocol

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  30. Tumor-infiltrating immune cells are present in various malignant tumors, but their clinical significance in gastric cancer (GC) remains unclear. This study aimed to investigate the prognostic significance of t...

    Authors: Jun Lu, Yu Xu, Yuan Wu, Xiao-yan Huang, Jian-wei Xie, Jia-bin Wang, Jian-xian Lin, Ping Li, Chao-hui Zheng, Ai-min Huang and Chang-ming Huang

    Citation: BMC Cancer 2019 19:920

    Content type: Research article

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  31. Gastrointestinal stromal tumor (GIST) is the most common primary mesenchymal neoplasm of the gastrointestinal tract. Mutations of KIT and platelet-derived growth factor receptor alpha have been well characteri...

    Authors: Li Li, Marian Khalili, Gregg Johannes, Praneeth Baratam, William F. Morano, Michael Styler, Wilbur B. Bowne and J. Steve Hou

    Citation: BMC Cancer 2019 19:913

    Content type: Case report

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  32. The sensitivity of endoscopic ultrasound (EUS) in staging gastro-oesophageal cancers (GOCs) has been widely studied. However, the economic evidence of EUS staging in the management of patients with GOCs is sca...

    Authors: Seow Tien Yeo, Nathan Bray, Hasan Haboubi, Zoe Hoare and Rhiannon Tudor Edwards

    Citation: BMC Cancer 2019 19:900

    Content type: Research article

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  33. To evaluate the short- and long-term outcomes of 3 different endoscopic dissection techniques for upper gastrointestinal (GI) submucosal tumours (SMTs).

    Authors: Xi-Feng Jin, Wei Gai, Rong-Lian Du, Tong-Hai Chai, Ling Li and Christoph J. Auernhammer

    Citation: BMC Cancer 2019 19:893

    Content type: Research article

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  34. Soft-tissue sarcomas (STS) are rare malignant tumors those are resistant to chemotherapy. We have previously reported the 3-year follow-up result on the efficacy of perioperative chemotherapy with doxorubicin ...

    Authors: Kazuhiro Tanaka, Junki Mizusawa, Norifumi Naka, Akira Kawai, Hirohisa Katagiri, Toru Hiruma, Yoshihiro Matsumoto, Hiroyuki Tsuchiya, Robert Nakayama, Hiroshi Hatano, Makoto Emori, Munenori Watanuki, Yukihiro Yoshida, Takeshi Okamoto, Satoshi Abe, Kunihiro Asanuma…

    Citation: BMC Cancer 2019 19:890

    Content type: Research article

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  35. Our purpose was to examine the outcomes of patients who underwent extensive resection of periacetabular tumors involving the sacroiliac joint and joint reconstruction with a hemipelvic endoprosthesis.

    Authors: Bo Wang, Changye Zou, Xiaokun Hu, Jian Tu, Hao Yao, Junqiang Yin, Gang Huang, Xianbiao Xie and Jingnan Shen

    Citation: BMC Cancer 2019 19:861

    Content type: Research article

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  36. We report on our experience of ultrasound (US)-guided dual-localization for axillary nodes before and after neoadjuvant chemotherapy (NAC) with clip and activated charcoal to guide axillary surgery in breast c...

    Authors: Won Hwa Kim, Hye Jung Kim, See Hyung Kim, Jin Hyang Jung, Ho Yong Park, Jeeyeon Lee, Wan Wook Kim, Ji Young Park, Yee Soo Chae and Soo Jung Lee

    Citation: BMC Cancer 2019 19:859

    Content type: Research article

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  37. Recently, evidence has emerged that palliative gastrectomy in patients with stage IV gastric cancer may offer some survival benefits. However, the decision whether to perform primary tumor surgery remains chal...

    Authors: Tai Ma, Zhi-jun Wu, Hui Xu, Chang-hao Wu, Jing Xu, Wan-ren Peng, Lu-lu Fan and Guo-ping Sun

    Citation: BMC Cancer 2019 19:852

    Content type: Research article

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  38. Studies over the past 10 years strongly support an association between skeletal muscle mass (SMM) depletion and outcome in metastatic colorectal cancer (mCRC). Factors influencing SMM changes over time are, ho...

    Authors: Sami Antoun, Mohamed Amine Bayar, Valérie Dyevre, Emilie Lanoy, Cristina Smolenschi and Michel Ducreux

    Citation: BMC Cancer 2019 19:847

    Content type: Research article

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  39. The prognosis of ductal carcinoma in situ (DCIS) is reportedly well. Extremely rare patients with DCIS develop distant breast cancer metastasis without locoregional or contralateral recurrence. This is the fir...

    Authors: Qiuting You, Yichao Fang, Chenchen Li, Yujie Tan, Jianli Zhao, Cui Tan, Ying Wang, Herui Yao and Fengxi Su

    Citation: BMC Cancer 2019 19:844

    Content type: Case report

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  40. Blood counting and the liver function tests, as the routine examinations, can reflect the immune and nutritional status of the body, our aim is to assess the prognostic significance of serum gamma-glutamyltran...

    Authors: Li-xiang Zhang, Yang Lv, A-Man Xu and Huan-zhong Wang

    Citation: BMC Cancer 2019 19:841

    Content type: Research article

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  41. Adrenal tumors in patients with previous/synchronous extra-adrenal malignancy are diverse and are a dilemma in clinical practice. This study investigated the differentiation of adrenal malignant and benign tum...

    Authors: Lei Tan, Yunlin Ye, Kanghua Xiao, Xuelian Xu, Haitao Liang, Fufu Zheng and Zike Qin

    Citation: BMC Cancer 2019 19:838

    Content type: Research article

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  42. Current advancements in neoadjuvant therapy and total mesorectal excision have engendered increased local control. However, the survival benefit of preoperative radiotherapy (RT; 5 × 5 Gy) in rectal cancer pat...

    Authors: Yi-Hung Kuo, Chia-Hsuan Lai, Cheng-Yi Huang, Chih-Jung Chen, Yun-Ching Huang, Wen-Shih Huang and Chih-Chien Chin

    Citation: BMC Cancer 2019 19:815

    Content type: Research article

    Published on: