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Surgical oncology, cancer imaging, and interventional therapeutics

Section edited by Stephen P. Povoski

This section focuses on clinical research that impacts on the diagnosis and treatment of cancer using surgery, diagnostic imaging, interventional therapeutics, and surgical pathology.

Page 1 of 11

  1. Content type: Research article

    99mTc-Rituximab is a new specific radiopharmaceutical that binds to the CD20 receptor which is highly expressed on the surface of B cells. We conducted a study in which 99mTc-Rituximab was compared with filtered

    Authors: Jing-Jie Zhang, Wan-Chun Zhang, Cai-Xia An, Xiao-Min Li and Le Ma

    Citation: BMC Cancer 2019 19:956

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  2. Content type: Research article

    Lymph-node (LN) metastasis is an important prognostic factor in resected pancreatic cancer. In this study, the prognostic value of American Joint Committee on Cancer (AJCC) 8th edition N stage, lymph-node rati...

    Authors: Min Su You, Sang Hyub Lee, Young Hoon Choi, Bang-sup Shin, Woo Hyun Paik, Ji Kon Ryu, Yong-Tae Kim, Dong Kee Jang, Jun Kyu Lee, Wooil Kwon, Jin-Young Jang and Sun-Whe Kim

    Citation: BMC Cancer 2019 19:952

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  3. Content type: Research article

    Biliary rhabdomyosarcoma (RMS) is the most common biliary tumor in children. The management of affected patients contains unique challenges because of the rarity of this tumor entity and its critical location ...

    Authors: Cristian Urla, Steven W. Warmann, Monika Sparber-Sauer, Andreas Schuck, Ivo Leuschner, Thomas Klingebiel, Gunnar Blumenstock, Guido Seitz, Ewa Koscielniak and Jörg Fuchs

    Citation: BMC Cancer 2019 19:945

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  4. Content type: Research article

    This preliminary study aimed to examine the feasibility of sentinel lymph node biopsy (SLNB) using contrast-enhanced ultrasound (CEUS) vs. indocyanine green fluorescence (ICG), combined with blue dye in patien...

    Authors: Yidong Zhou, Yan Li, Feng Mao, Jing Zhang, Qingli Zhu, Songjie Shen, Yan Lin, Xiaohui Zhang, He Liu, Mengsu Xiao, Yuxin Jiang and Qiang Sun

    Citation: BMC Cancer 2019 19:939

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  5. Content type: Research article

    To investigate the implications of prophylactic intraoperative Hyperthermic Intraperitoneal Chemotherapy (HIPEC) with D2 radical gastrectomy for locally advanced Gastric Cancer (AGC) in a randomized case contr...

    Authors: Maneesh Kumarsing Beeharry, Zheng-Lun Zhu, Wen-Tao Liu, Xue-Xin Yao, Min Yan and Zheng-Gang Zhu

    Citation: BMC Cancer 2019 19:932

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  6. Content type: Research article

    Preoperative 5-FU-based chemoradiation is currently a standard treatment for advanced rectal cancer, particularly in Western countries. Although it reduced the local recurrence, it could not necessarily improv...

    Authors: Tsunekazu Mizushima, Masataka Ikeda, Takeshi Kato, Atsuyo Ikeda, Junichi Nishimura, Taishi Hata, Chu Matsuda, Taroh Satoh, Masaki Mori and Yuichiro Doki

    Citation: BMC Cancer 2019 19:929

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  7. Content type: Study protocol

    Pancreatic adenocarcinoma is a high-mortality neoplasm with a documented 5-years-overall survival around 5%. In the last decades, a real breakthrough in the treatment of the disease has not been achieved. Here...

    Authors: Viviana Vitolo, Lorenzo Cobianchi, Silvia Brugnatelli, Amelia Barcellini, Andrea Peloso, Angelica Facoetti, Alessandro Vanoli, Sara Delfanti, Lorenzo Preda, Silvia Molinelli, Catherine Klersy, Piero Fossati, Roberto Orecchia and Francesca Valvo

    Citation: BMC Cancer 2019 19:922

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  8. Content type: Research article

    Tumor-infiltrating immune cells are present in various malignant tumors, but their clinical significance in gastric cancer (GC) remains unclear. This study aimed to investigate the prognostic significance of t...

    Authors: Jun Lu, Yu Xu, Yuan Wu, Xiao-yan Huang, Jian-wei Xie, Jia-bin Wang, Jian-xian Lin, Ping Li, Chao-hui Zheng, Ai-min Huang and Chang-ming Huang

    Citation: BMC Cancer 2019 19:920

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  9. Content type: Case report

    Gastrointestinal stromal tumor (GIST) is the most common primary mesenchymal neoplasm of the gastrointestinal tract. Mutations of KIT and platelet-derived growth factor receptor alpha have been well characteri...

    Authors: Li Li, Marian Khalili, Gregg Johannes, Praneeth Baratam, William F. Morano, Michael Styler, Wilbur B. Bowne and J. Steve Hou

    Citation: BMC Cancer 2019 19:913

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  10. Content type: Research article

    The sensitivity of endoscopic ultrasound (EUS) in staging gastro-oesophageal cancers (GOCs) has been widely studied. However, the economic evidence of EUS staging in the management of patients with GOCs is sca...

    Authors: Seow Tien Yeo, Nathan Bray, Hasan Haboubi, Zoe Hoare and Rhiannon Tudor Edwards

    Citation: BMC Cancer 2019 19:900

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  11. Content type: Research article

    To evaluate the short- and long-term outcomes of 3 different endoscopic dissection techniques for upper gastrointestinal (GI) submucosal tumours (SMTs).

    Authors: Xi-Feng Jin, Wei Gai, Rong-Lian Du, Tong-Hai Chai, Ling Li and Christoph J. Auernhammer

    Citation: BMC Cancer 2019 19:893

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  12. Content type: Research article

    Soft-tissue sarcomas (STS) are rare malignant tumors those are resistant to chemotherapy. We have previously reported the 3-year follow-up result on the efficacy of perioperative chemotherapy with doxorubicin ...

    Authors: Kazuhiro Tanaka, Junki Mizusawa, Norifumi Naka, Akira Kawai, Hirohisa Katagiri, Toru Hiruma, Yoshihiro Matsumoto, Hiroyuki Tsuchiya, Robert Nakayama, Hiroshi Hatano, Makoto Emori, Munenori Watanuki, Yukihiro Yoshida, Takeshi Okamoto, Satoshi Abe, Kunihiro Asanuma…

    Citation: BMC Cancer 2019 19:890

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  13. Content type: Research article

    Our purpose was to examine the outcomes of patients who underwent extensive resection of periacetabular tumors involving the sacroiliac joint and joint reconstruction with a hemipelvic endoprosthesis.

    Authors: Bo Wang, Changye Zou, Xiaokun Hu, Jian Tu, Hao Yao, Junqiang Yin, Gang Huang, Xianbiao Xie and Jingnan Shen

    Citation: BMC Cancer 2019 19:861

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  14. Content type: Research article

    We report on our experience of ultrasound (US)-guided dual-localization for axillary nodes before and after neoadjuvant chemotherapy (NAC) with clip and activated charcoal to guide axillary surgery in breast c...

    Authors: Won Hwa Kim, Hye Jung Kim, See Hyung Kim, Jin Hyang Jung, Ho Yong Park, Jeeyeon Lee, Wan Wook Kim, Ji Young Park, Yee Soo Chae and Soo Jung Lee

    Citation: BMC Cancer 2019 19:859

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  15. Content type: Research article

    Recently, evidence has emerged that palliative gastrectomy in patients with stage IV gastric cancer may offer some survival benefits. However, the decision whether to perform primary tumor surgery remains chal...

    Authors: Tai Ma, Zhi-jun Wu, Hui Xu, Chang-hao Wu, Jing Xu, Wan-ren Peng, Lu-lu Fan and Guo-ping Sun

    Citation: BMC Cancer 2019 19:852

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  16. Content type: Research article

    Studies over the past 10 years strongly support an association between skeletal muscle mass (SMM) depletion and outcome in metastatic colorectal cancer (mCRC). Factors influencing SMM changes over time are, ho...

    Authors: Sami Antoun, Mohamed Amine Bayar, Valérie Dyevre, Emilie Lanoy, Cristina Smolenschi and Michel Ducreux

    Citation: BMC Cancer 2019 19:847

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  17. Content type: Case report

    The prognosis of ductal carcinoma in situ (DCIS) is reportedly well. Extremely rare patients with DCIS develop distant breast cancer metastasis without locoregional or contralateral recurrence. This is the fir...

    Authors: Qiuting You, Yichao Fang, Chenchen Li, Yujie Tan, Jianli Zhao, Cui Tan, Ying Wang, Herui Yao and Fengxi Su

    Citation: BMC Cancer 2019 19:844

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  18. Content type: Research article

    Blood counting and the liver function tests, as the routine examinations, can reflect the immune and nutritional status of the body, our aim is to assess the prognostic significance of serum gamma-glutamyltran...

    Authors: Li-xiang Zhang, Yang Lv, A-Man Xu and Huan-zhong Wang

    Citation: BMC Cancer 2019 19:841

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  19. Content type: Research article

    Adrenal tumors in patients with previous/synchronous extra-adrenal malignancy are diverse and are a dilemma in clinical practice. This study investigated the differentiation of adrenal malignant and benign tum...

    Authors: Lei Tan, Yunlin Ye, Kanghua Xiao, Xuelian Xu, Haitao Liang, Fufu Zheng and Zike Qin

    Citation: BMC Cancer 2019 19:838

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  20. Content type: Research article

    Current advancements in neoadjuvant therapy and total mesorectal excision have engendered increased local control. However, the survival benefit of preoperative radiotherapy (RT; 5 × 5 Gy) in rectal cancer pat...

    Authors: Yi-Hung Kuo, Chia-Hsuan Lai, Cheng-Yi Huang, Chih-Jung Chen, Yun-Ching Huang, Wen-Shih Huang and Chih-Chien Chin

    Citation: BMC Cancer 2019 19:815

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  21. Content type: Research article

    The co-occurrence of type 1 autoimmune pancreatitis (AIP) and pancreatic tumor (PaT) has been previously reported. Pure AIP cases have favorable prognosis and are primarily treated with steroids, while AIP cas...

    Authors: Pei Xiang, Xiaoling Zhang, Chaoyang Wang, Yuejiao Lang, Ling Xu, Li Huang, Jingxian Shen and Shi-Ting Feng

    Citation: BMC Cancer 2019 19:814

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  22. Content type: Research article

    The risk of lymph node positivity in early-stage colon cancer is a parameter that impacts therapeutic recommendations. However, little is known about the effect of age on lymph node positivity in colon cancer ...

    Authors: Xin Xie, Jianhao Yin, Zhangjian Zhou, Chengxue Dang, Hao Zhang and Yong Zhang

    Citation: BMC Cancer 2019 19:803

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  23. Content type: Case report

    We report an extremely rare case of vaginal clear cell carcinoma, which originated from the malignant transformation of vaginal adenosis without prenatal diethylstilbestrol (DES) exposure.

    Authors: Lihong Pang, Lei Li, Lan Zhu, Jinghe Lang and Yalan Bi

    Citation: BMC Cancer 2019 19:798

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  24. Content type: Research article

    To demonstrate that post-therapy pathological tumor volume (ypTV) should be considered as an independent prognostic factor in advanced gastric cancer (GC) patients who underwent neoadjuvant chemotherapy (NAC) ...

    Authors: Xiaolong Tang, Qingsi He, Hui Qu, Guorui Sun, Jia Liu, Lei Gao, Jingbo Shi, Jianhong Ye and Yahang Liang

    Citation: BMC Cancer 2019 19:797

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  25. Content type: Research article

    This study aimed to investigate the prognostic value of volumetric parameters on 18F- fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) in gastric-cancer patients, accor...

    Authors: Guobing Liu, Yan Hu, Xi Cheng, Yan Wang, Yushen Gu, Tianshu Liu and Hongcheng Shi

    Citation: BMC Cancer 2019 19:790

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  26. Content type: Research article

    The aim of this study was to compare the oncological outcomes and clinical efficacy of laparoscopic pancreaticoduodenectomy (LPD) and open pancreaticoduodenectomy (OPD) in patients with pancreatic ductal adeno...

    Authors: Yu-Li Jiang, Ren-Chao Zhang and Yu-Cheng Zhou

    Citation: BMC Cancer 2019 19:781

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  27. Content type: Case report

    ROS1 rearrangements are validated drivers in lung cancer, which have been identified in a small subset (1–2%) of patients with non-small cell lung cancer (NSCLC). To date, 18 fusion genes of ROS1 have been identi...

    Authors: Shuguang Xu, Wenxian Wang, Chunwei Xu, Xingliang Li, Junhui Ye, Youcai Zhu and Ting Ge

    Citation: BMC Cancer 2019 19:769

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  28. Content type: Case report

    Bladder leiomyosarcoma is the most frequent mesenchymal neoplasm of the bladder. However, the rarity of the disease and some morphological aspects could give serious problems to differential diagnosis.

    Authors: Vincenzo Fiorentino, Francesco Pierconti, Niccolò Lenci, Martina Calicchia, Giuseppe Palermo, Pierfrancesco Bassi, Luigi Maria Larocca and Maurizio Martini

    Citation: BMC Cancer 2019 19:763

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  29. Content type: Research article

    Efficacy of treatments for colorectal liver metastases after failure of first-line chemotherapy is limited. The aim of this study was to prospectively evaluate the feasibility, tolerability, and pharmacokineti...

    Authors: Toshihiro Tanaka, Takeshi Sato, Hideyuki Nishiofuku, Tetsuya Masada, Shota Tatsumoto, Nagaaki Marugami, Toshio Otsuji, Masatoshi Kanno, Fumikazu Koyama, Masayuki Sho and Kimihiko Kichikawa

    Citation: BMC Cancer 2019 19:758

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  30. Content type: Research article

    For brain metastases from non-specific primary tumors, the most frequently used and validated clinical prognostic assessment tool is Karnofsky performance status (KPS). Given the lack of prognostic factors of ...

    Authors: Jun Imaizumi, Dai Shida, Yoshitaka Narita, Yasuji Miyakita, Taro Tanabe, Atsuo Takashima, Narikazu Boku, Hiroshi Igaki, Jun Itami and Yukihide Kanemitsu

    Citation: BMC Cancer 2019 19:755

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  31. Content type: Research article

    The 8th edition of the tumor-node-metastasis (TNM) classification classifies inguinal lymph nodes as regional lymph nodes for anal canal carcinoma but non-regional lymph nodes for rectal carcinoma. This differ...

    Authors: Taro Tanabe, Dai Shida, Sho Komukai, Yuya Nakamura, Shunsuke Tsukamoto and Yukihide Kanemitsu

    Citation: BMC Cancer 2019 19:733

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  32. Content type: Research article

    Recently, the incidence of gastroesophageal junction (GEJ) cancer has been increasing in Eastern countries. Mediastinal lymph node (MLN) metastasis rates among patients with GEJ cancer are reported to be 5–25%...

    Authors: Won Ho Han, Bang Wool Eom, Hong Man Yoon, Daniel Reim, Young-Woo Kim, Moon Soo Kim, Jong Mog Lee and Keun Won Ryu

    Citation: BMC Cancer 2019 19:719

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  33. Content type: Research article

    Assessing the prognostic significance of specific clinicopathological features plays an important role in surgical management after radical cystectomy. This study investigated the association between ten clini...

    Authors: Lijin Zhang, Bin Wu, Zhenlei Zha, Wei Qu, Hu Zhao and Jun Yuan

    Citation: BMC Cancer 2019 19:716

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  34. Content type: Research article

    Hepatocellular carcinomas (HCC) arising in the caudate lobe is rare and the treatment is difficult. The aim of this study is to summarize the experience of ultrasound-guided percutaneous ablation therapy for H...

    Authors: Baoxian Liu, Jianting Long, Wei Wang, Tongyi Huang, Xiaohua Xie, Shuling Chen, Guangliang Huang, Chunlin Jiang, Jieyi Ye, Haiyi Long, Xiaoyan Xie and Ming Kuang

    Citation: BMC Cancer 2019 19:699

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  35. Content type: Research article

    To evaluate the safety and efficacy of intra-arterial chemotherapy (IAC) for the primary or secondary treatment of infants diagnosed with advanced retinoblastoma before 3 months of age.

    Authors: Qiuying Chen, Bin Zhang, Yuhao Dong, Xiaokai Mo, Lu Zhang, Jiejun Xia, Jing Zhang and Shuixing Zhang

    Citation: BMC Cancer 2019 19:693

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  36. Content type: Research article

    Lung cancer is the most important cause of cancer-related deaths worldwide and the overall survival of patients with non-small cell lung cancer has not improved. Transforming growth factor beta or TGF-β is a p...

    Authors: Jue Li, Cheng Shen, Xin Wang, Yutian Lai, Kun Zhou, Pengfei Li, Lunxu Liu and Guowei Che

    Citation: BMC Cancer 2019 19:691

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  37. Content type: Case report

    Chronic lymphocytic leukemia is a malignancy with good prognosis. However, the incidence of secondary tumors increases every year after the diagnosis of chronic lymphotcytic leukemia. One of the induced second...

    Authors: Yinjie Zhu, Yanqing Wang, Zhiyu Qian, Jiahua Pan, Qiang Liu, Baijun Dong and Wei Xue

    Citation: BMC Cancer 2019 19:676

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  38. Content type: Research article

    The neutrophil–lymphocyte ratio (NLR) and platelet–lymphocyte ratio (PLR) are representative blood markers of systemic inflammatory responses. However, the clinical significance of the combination of these mar...

    Authors: Tetsushi Hirahara, Takaaki Arigami, Shigehiro Yanagita, Daisuke Matsushita, Yasuto Uchikado, Yoshiaki Kita, Shinichiro Mori, Ken Sasaki, Itaru Omoto, Hiroshi Kurahara, Kosei Maemura, Keishi Okubo, Yoshikazu Uenosono, Sumiya Ishigami and Shoji Natsugoe

    Citation: BMC Cancer 2019 19:672

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  39. Content type: Case report

    Stereotactic radiotherapy is an emerging treatment option for patients with inoperable renal cell carcinoma (RCC). Haemorrhage has not previously been reported to occur as a result of Stereotactic Body Radioth...

    Authors: Liam A. Hilleary, Christopher Wratten, Shankar Siva, Jenna Hilleary and Jarad M. Martin

    Citation: BMC Cancer 2019 19:671

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  40. Content type: Research article

    Breast cancer survivors are at risk of developing breast cancer-related lymphedema (BCRL) after surgical treatment, which may have a negative effect on quality of life. The purpose of this study was to investi...

    Authors: Sung Mook Lim, Yujin Han, Seung Il Kim and Hyung Seok Park

    Citation: BMC Cancer 2019 19:669

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  41. Content type: Study protocol

    An important parameter for survival in patients with esophageal carcinoma is lymph node status. The distribution of lymph node metastases depends on tumor characteristics such as tumor location, histology, inv...

    Authors: Eliza R. C. Hagens, Mark I. van Berge Henegouwen, Johanna W. van Sandick, Miguel A. Cuesta, Donald L. van der Peet, Joos Heisterkamp, Grard A. P. Nieuwenhuijzen, Camiel Rosman, Joris J. G. Scheepers, Meindert N. Sosef, Richard van Hillegersberg, Sjoerd M. Lagarde, Magnus Nilsson, Jari Räsänen, Philippe Nafteux, Piet Pattyn…

    Citation: BMC Cancer 2019 19:662

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  42. Content type: Research article

    Yes-associated protein (YAP) plays a crucial role in tumour development and it is the main effector of the Hippo signalling pathway. However, the mechanism underlying YAP downregulation in laryngeal cancer is ...

    Authors: Xiaomin Tang, Yuxuan Sun, Ganglun Wan, Jiaqiang Sun, Jingwu Sun and Chunchen Pan

    Citation: BMC Cancer 2019 19:654

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  43. Content type: Research article

    The optimal reconstructive method after diaphyseal malignant bone tumor resection remains controversial. This multicenter clinical study was designed to investigate the clinical value and complications of segm...

    Authors: Kai Zheng, Xiu-chun Yu, Yong-cheng Hu, Zeng-wu Shao, Ming Xu, Bai-chuan Wang and Feng Wang

    Citation: BMC Cancer 2019 19:638

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