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Supportive therapy, survivorship and psychosocial oncology

This section focuses on clinical research in the field of supportive therapy for short and long term effects (including emesis, pain, bone metastases, orphan symptoms, simultaneous care, elderly, comorbidities, emerging toxicities induced by innovative drugs, etc) induced by cancer therapies, along with their impact on quality of life, survivorship and well-being. This section will also consider material on the field of precision medicine in supportive therapy, but also on patient care and psychosocial oncology.

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  1. Content type: Research article

    Cancer is one of the leading causes of morbidity and mortality worldwide. Seventy percent of deaths of cancer occur in low or middle-income countries, where the resources to provide cancer treatment and care a...

    Authors: Thecla W. Kohi, Louise von Essen, Golden M. Masika, Maria Gottvall and Justine Dol

    Citation: BMC Cancer 2019 19:82

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  2. Content type: Research article

    Medical oncology outpatients are a group for whom advance care planning (ACP) activities are particularly relevant. Patient views can help prioritise areas for improving end of life communication. The study ai...

    Authors: Amy Waller, Heidi Turon, Jamie Bryant, Alison Zucca, Tiffany-Jane Evans and Rob Sanson-Fisher

    Citation: BMC Cancer 2019 19:63

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  3. Content type: Research article

    The Symptom Screening in Pediatrics Tool (SSPedi) is valid for assessing symptoms in children aged 8–18 years receiving cancer treatments. The objective was to develop a new self-report symptom screening tool ...

    Authors: Deborah Tomlinson, Shannon Hyslop, Eliana Stein, Brenda Spiegler, Emily Vettese, Susan Kuczynski, Tal Schechter, L. Lee Dupuis and Lillian Sung

    Citation: BMC Cancer 2019 19:32

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  4. Content type: Study protocol

    More than 60% of women diagnosed with early stage breast cancer receive (neo)adjuvant chemotherapy. Breast cancer patients receiving chemotherapy often experience symptoms such as nausea, vomiting and loss of ...

    Authors: J. Th. C. M. de Kruif, M. Visser, M. M. G. A. van den Berg, M. J. M. Derks, M. R. de Boer, H. W. M. van Laarhoven, J. H. M. de Vries, Y. C. de Vries, E. Kampman, R. W. Winkels and M. J. Westerman

    Citation: BMC Cancer 2019 19:7

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  5. Content type: Research article

    Existing evidence demonstrates that 1:1 personal training (PT) improves many adverse effects of androgen deprivation therapy (ADT). Whether less resource-intensive exercise delivery models are as effective rem...

    Authors: Shabbir M. H. Alibhai, Daniel Santa Mina, Paul Ritvo, George Tomlinson, Catherine Sabiston, Murray Krahn, Sara Durbano, Andrew Matthew, Padraig Warde, Meagan O’Neill, Narhari Timilshina, Roanne Segal and Nicole Culos-Reed

    Citation: BMC Cancer 2019 19:2

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  6. Content type: Research article

    Cancer patients’ survival time has obviously improved, with the development of systemic treatment techniques. However, the probability of metastases to the vertebrae has also been increased which makes some ad...

    Authors: Xiong-gang Yang, Deng-xing Lun, Yong-cheng Hu, Yong-heng Liu, Feng Wang, Jiang-tao Feng, Kun-chi Hua, Li Yang, Hao Zhang, Ming-you Xu and Hao-ran Zhang

    Citation: BMC Cancer 2018 18:1248

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  7. Content type: Research article

    Many studies have reported the prognostic value of haemoglobin level for cancers. Whereas the prognostic impact of decreased pretreatment haemoglobin level on the survival of patients with lung cancer remains ...

    Authors: Yaqi Huang, Siqi Wei, Nan Jiang, Lijuan Zhang, Siyuan Wang, Xiaona Cao, Yue Zhao and Peiguo Wang

    Citation: BMC Cancer 2018 18:1235

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  8. Content type: Research article

    Measuring quality of life is important for cancer patients, but there are regional differences in age-standardized colorectal cancer incidence and mortality rates which may affect measurement. This study aimed...

    Authors: Min Liu, Wei Sun, Yuan-Yi Cai and Hua-Zhang Wu

    Citation: BMC Cancer 2018 18:1228

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  9. Content type: Research article

    The Body Image Scale (BIS) is a 10-item mono-factorial scale, designed to capture distress and symptoms related to body image in cancer patients. This paper describes the conversion and psychometric evaluation...

    Authors: Maria Antonietta Annunziata, Barbara Muzzatti, Francesca Bomben, Cristiana Flaiban, Marika Piccinin and Valentina Solfrini

    Citation: BMC Cancer 2018 18:1222

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  10. Content type: Study protocol

    The growing numbers of cancer survivors challenge delivery of high-quality survivorship care by healthcare systems. Innovative ways to improve care coordination for patients with cancer and multiple chronic co...

    Authors: Simon J. Craddock Lee, Katelyn K. Jetelina, Emily Marks, Eric Shaw, Kevin Oeffinger, Deborah Cohen, Noel O. Santini, John V. Cox and Bijal A. Balasubramanian

    Citation: BMC Cancer 2018 18:1204

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  11. Content type: Research article

    Impaired physical function due to chemotherapy-induced peripheral neuropathy (CIPN) symptoms may lead to diminished quality of life. However, even with the knowledge of the effects of CIPN on physical function...

    Authors: Robert Knoerl, Edie Weller, Barbara Halpenny and Donna Berry

    Citation: BMC Cancer 2018 18:1203

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  12. Content type: Study protocol

    Cancers of the upper gastrointestinal tract commonly result in malnutrition, which increases morbidity and mortality. Current nutrition best practice lacks a mechanism to provide early and intensive nutrition ...

    Authors: Kate Furness, Catherine E. Huggins, Lauren Hanna, Mary Anne Silvers, Paul Cashin, Liang Low, Daniel Croagh and Terry P. Haines

    Citation: BMC Cancer 2018 18:1181

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  13. Content type: Research article

    Few studies have focused on quality of life (QoL) after treatment of malignant pleural mesothelioma (MPM). There are still questions as to which surgical procedure, extrapleural pneumonectomy (EPP) or pleurect...

    Authors: Rebecca M. Schwartz, Wil Lieberman-Cribbin, Andrea Wolf, Raja M. Flores and Emanuela Taioli

    Citation: BMC Cancer 2018 18:1188

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  14. Content type: Research article

    Oesophageal carcinoma is one of the leading cancers in Sri Lanka. Recent advances in treatment modalities have drastically improved the survival of these patients. However, the quality of life (QoL) among the ...

    Authors: Ishanka Ayeshwari Talagala and Carukshi Arambepola

    Citation: BMC Cancer 2018 18:1184

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  15. Content type: Research article

    Cachexia is a multisystem syndrome characterized by weight loss, anorexia, loss of muscle mass, systemic inflammation, insulin resistance, and functional decline. Management of cachexia involves addressing mul...

    Authors: Shailesh M. Advani, Pragati G. Advani, Helena M. VonVille and Syed H. Jafri

    Citation: BMC Cancer 2018 18:1174

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  16. Content type: Research article

    Breast cancer survivors have an elevated risk of cognitive impairment compared to age-matched women without cancer. Causes of this impairment are complex, including both treatment and psychological factors. Mi...

    Authors: Gabriella Cifu, Melinda C. Power, Sarah Shomstein and Hannah Arem

    Citation: BMC Cancer 2018 18:1163

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  17. Content type: Research article

    Decision making with advanced cancer patients is often associated with decisional conflict regarding treatment outcomes. This longitudinal multicenter study investigated German physicians’ course of decisional...

    Authors: Catharina Schoenfeld, Yves Libert, Heribert Sattel, Delphine Canivet, France Delevallez, Andreas Dinkel, Pascal O. Berberat, Alexander Wuensch and Darius Razavi

    Citation: BMC Cancer 2018 18:1161

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  18. Content type: Research article

    The group of colorectal cancer (CRC) survivors continues to grow worldwide. Understanding health-related quality of life (HRQOL) determinants and consequences of HRQOL impairments in long-term CRC survivors ma...

    Authors: Ilka Ratjen, Clemens Schafmayer, Janna Enderle, Romina di Giuseppe, Sabina Waniek, Manja Koch, Greta Burmeister, Ute Nöthlings, Jochen Hampe, Sabrina Schlesinger and Wolfgang Lieb

    Citation: BMC Cancer 2018 18:1156

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  19. Content type: Research article

    Individuals with cancer have reduced quality of life, functionality, range of motion, strength, and an increase in pain and fatigue. Exergaming appears to be an effective rehabilitation tool for Parkinson’s di...

    Authors: Daniel Tough, Jonathan Robinson, Steven Gowling, Peter Raby, John Dixon and Samantha L. Harrison

    Citation: BMC Cancer 2018 18:1151

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  20. Content type: Study protocol

    African American adults experience a disproportionate burden and increased mortality for most solid tumor cancers and their adolescent children are negatively impacted by the illness experience. The purpose of...

    Authors: Nicole S. McKinney, Shannon Virtue, Frances Marcus Lewis, Alliric I. Willis, Tanisha Pettyjohn, La-Rhonda Harmon and Adam Davey

    Citation: BMC Cancer 2018 18:1140

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  21. Content type: Research article

    Outpatient autologous stem cell transplantations (ASCTs) in multiple myeloma and lymphoma patients have been shown to reduce the overall costs and improve the quality of life relative to inpatient ASCTs. This ...

    Authors: Weerapat Owattanapanich, Kittima Suphadirekkul, Chutima Kunacheewa, Patompong Ungprasert and Kannadit Prayongratana

    Citation: BMC Cancer 2018 18:1126

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  22. Content type: Study protocol

    Cancer has a lot of consequences on patients’ quality of life (such as cancer-related fatigue (CRF), sleep difficulties and emotional distress) and on patients’ partners and their relationship, such as distres...

    Authors: Charlotte Grégoire, Marie-Elisabeth Faymonville, Audrey Vanhaudenhuyse, Vanessa Charland-Verville, Guy Jerusalem and Isabelle Bragard

    Citation: BMC Cancer 2018 18:1113

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  23. Content type: Research article

    Given the high cure-rate for testicular cancer (TC) and the patients’ young age, comprehensive evaluation of health-related quality of life (HRQOL) is an important consideration in this patient population. The...

    Authors: Monika Sztankay, Neil K. Aaronson, Juan I. Arraras, Umberto Basso, Uros Bumbasirevic, Fabio Efficace, Johannes M. Giesinger, Colin D. Johnson, Marieke van Leeuwen, Anne S. Oberguggenberger, Roman Sosnowski, Teresa Young and Bernhard Holzner

    Citation: BMC Cancer 2018 18:1104

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  24. Content type: Research article

    Utility weight, a measure of health-related quality of life, is used in disease burden measurements and economic evaluations. In this study, we used the visual analogue scale (VAS) and standard gamble (SG) met...

    Authors: Eun-Jung Kim, Minsu Ock, Kyu-pyo Kim, Nuri Hyun Jung, Hyeon-Jeong Lee, Seon-Ha Kim and Min-Woo Jo

    Citation: BMC Cancer 2018 18:1081

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  25. Content type: Study protocol

    Health service change is difficult to achieve. One strategy to facilitate such change is the clinical pathway, a guide for clinicians containing a defined set of evidence-based interventions for a specific con...

    Authors: Phyllis Butow, Joanne Shaw, Heather L. Shepherd, Melanie Price, Lindy Masya, Brian Kelly, Nicole M. Rankin, Afaf Girgis, Thomas F. Hack, Philip Beale, Rosalie Viney, Haryana M. Dhillon, Joseph Coll, Patrick Kelly, Melanie Lovell, Peter Grimison…

    Citation: BMC Cancer 2018 18:1077

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  26. Content type: Study protocol

    Up to 80% of breast cancer patients suffer from Cancer Related Cognitive Impairments (CRCI). Exercise is suggested as a potential supportive care option to reduce cognitive decline in cancer patients. This stu...

    Authors: Max Oberste, Nils Schaffrath, Katharina Schmidt, Wilhelm Bloch, Elke Jäger, Karen Steindorf, Philipp Hartig, Niklas Joisten and Philipp Zimmer

    Citation: BMC Cancer 2018 18:1071

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  27. Content type: Study protocol

    Higher levels of physical activity (PA) after treatment are associated with beneficial effects on physical and psychosocial functioning of cancer survivors. However, survivors often do not meet the recommended...

    Authors: H. J. van de Wiel, M. M. Stuiver, A. M. May, S. van Grinsven, N. K. Aaronson, V. P. Retèl, H. S. A. Oldenburg, H. G. van der Poel, S. Horenblas, W. H. van Harten and W. G. Groen

    Citation: BMC Cancer 2018 18:1073

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  28. Content type: Research article

    A patient’s physical function plays a leading role in the treatment prescription for patients with cancer. Objective assessments of physical function may be more predictive for treatment tolerability and survi...

    Authors: Joeri A. J. Douma, Henk M. W. Verheul and Laurien M. Buffart

    Citation: BMC Cancer 2018 18:1052

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  29. Content type: Study protocol

    Androgen deprivation therapy (ADT) is commonly used to treat prostate cancer. However, side effects of ADT often lead to reduced quality of life and physical function. Existing evidence demonstrates that exerc...

    Authors: Shabbir M. H. Alibhai, Paul Ritvo, Daniel Santa Mina, Catherine Sabiston, Murray Krahn, George Tomlinson, Andrew Matthew, Himu Lukka, Padraig Warde, Sara Durbano, Meagan O’Neill and S. Nicole Culos-Reed

    Citation: BMC Cancer 2018 18:1031

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  30. Content type: Research article

    How patients recover and resume everyday life after curative hepato-pancreato-biliary (HPB) surgery with intestinal reconstruction has, to our knowledge, not previously been investigated. We wanted to explore ...

    Authors: Kristine Elberg Dengsø, Tine Tjørnhøj-Thomsen, Susanne Oksbjerg Dalton, Bo Marcel Christensen, Jens Hillingsø and Thordis Thomsen

    Citation: BMC Cancer 2018 18:1017

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  31. Content type: Research article

    Colorectal cancer is a significant issue internationally, with over 1.3 million people diagnosed annually. Survival rates are increasing as treatments improve, although physical symptoms can persist despite er...

    Authors: Claire O’Gorman, Jim Stack, Alan O’Ceilleachair, Suzanne Denieffe, Martina Gooney, Martina McKnight and Linda Sharp

    Citation: BMC Cancer 2018 18:1022

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  32. Content type: Research article

    Fear of cancer recurrence (FCR) has been shown to be higher in patients treated with external beam radiotherapy (RT) compared to those untreated. However, little is known about the dynamics of patient’s FCR du...

    Authors: Y. Yang, J. Cameron, C. Bedi and G. Humphris

    Citation: BMC Cancer 2018 18:1002

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  33. Content type: Research article

    Decrease in bone mineral density, osteoporosis development, bone toxicity and resulting insufficiency fractures as late effect of radiotherapy are not well known. Osteoporosis development related to radiothera...

    Authors: Gokhan Yaprak, Cengiz Gemici, Sule Temizkan, Sevim Ozdemir, Berfu Cinkit Dogan and Ozgur Ozan Seseogullari

    Citation: BMC Cancer 2018 18:972

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  34. Content type: Research article

    Paclitaxel induced peripheral neuropathy (PIPN) is a major debilitating side effect of paclitaxel in patients with breast cancer with no fully known mechanisms. The aim of the study was to find out the possibl...

    Authors: Zohreh Ghoreishi, Seyedali Keshavarz, Mohammad Asghari Jafarabadi, Zahra Fathifar, Karyn A Goodman and Ali Esfahani

    Citation: BMC Cancer 2018 18:958

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  35. Content type: Research article

    Patients’ quality of life has become a major objective of care in oncology. At the same time, it has become the object of increasing interest by researchers, working with both quantitative and qualitative meth...

    Authors: Jordan Sibeoni, Camille Picard, Massimiliano Orri, Mathilde Labey, Guilhem Bousquet, Laurence Verneuil and Anne Revah-Levy

    Citation: BMC Cancer 2018 18:951

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  36. Content type: Study protocol

    Many studies have shown that lifestyle factors such as diet, physical activity are related to the incidence of cancer. However, there are few studies on the association between lifestyle factors and cancer pro...

    Authors: Yuri Mizota, Yukihide Kanemitsu, Shunsuke Tsukamoto, Dai Shida, Hiroki Ochiai and Seiichiro Yamamoto

    Citation: BMC Cancer 2018 18:953

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  37. Content type: Study protocol

    Several intervention studies have demonstrated that exercise training has beneficial effects among cancer patients. However, older cancer patients are underrepresented in clinical trials, and only few exercise...

    Authors: Marta Kramer Mikkelsen, Cecilia Margareta Lund, Anders Vinther, Anders Tolver, Anne-Mette Ragle, Julia Sidenius Johansen, Inna Chen, Lotte Engell-Noerregaard, Finn Ole Larsen, Bo Zerahn, Dorte Lisbet Nielsen and Mary Jarden

    Citation: BMC Cancer 2018 18:934

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  38. Content type: Research article

    Hospitalized cancer patients undergoing intensive or high-dose chemotherapy often experience a considerable decline in functional performance associated with the increased risk of adverse health events. Exerci...

    Authors: Antonia Pahl, Anja Wehrle, Sarah Kneis, Albert Gollhofer and Hartmut Bertz

    Citation: BMC Cancer 2018 18:920

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  39. Content type: Study protocol

    Patients undergoing chemotherapy are highly burdened by side effects. These may be caused by the pharmacodynamics of the drug or be driven by psychological factors such as negative expectations or pre-conditio...

    Authors: Julia Quidde, Yiqi Pan, Melanie Salm, Armin Hendi, Sven Nilsson, Karin Oechsle, Alexander Stein and Yvonne Nestoriuc

    Citation: BMC Cancer 2018 18:916

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  40. Content type: Research article

    Women diagnosed with gynaecological cancer experience supportive care needs that require care provision to reduce the impact on their lives. International evidence suggests supportive care needs of women with ...

    Authors: Natalie Williams, Georgia Griffin, Victoria Farrell, Alethea Rea, Kevin Murray and Yvonne L. Hauck

    Citation: BMC Cancer 2018 18:912

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  41. Content type: Research article

    Physical exercise and nutritional treatment are promising measures to prevent muscle wasting that is frequently observed in advanced-stage cancer patients. However, conventional exercise is not always suitable...

    Authors: Kristin Schink, Hans J. Herrmann, Raphaela Schwappacher, Julia Meyer, Till Orlemann, Elisabeth Waldmann, Bernd Wullich, Andreas Kahlmeyer, Rainer Fietkau, Dorota Lubgan, Matthias W. Beckmann, Carolin Hack, Wolfgang Kemmler, Jürgen Siebler, Markus F. Neurath and Yurdagül Zopf

    Citation: BMC Cancer 2018 18:886

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  42. Content type: Study protocol

    Cancer related fatigue (CRF) is one of the most prevalent and distressing long-term complaints reported by (non-) Hodgkin survivors. To date there has been no standard treatment for CRF in this population. A n...

    Authors: Daniëlle E. J. Starreveld, Laurien A. Daniels, Heiddis B. Valdimarsdottir, William H. Redd, Jessie L. de Geus, Sonia Ancoli-Israel, Susan Lutgendorf, Catharina M. Korse, Jacobien M. Kieffer, Flora E. van Leeuwen and Eveline M. A. Bleiker

    Citation: BMC Cancer 2018 18:880

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  43. Content type: Research article

    Although there is a recognition of the importance of fertility to young women with cancer, we do not know who is at risk of distress related to fertility issues following diagnosis. We investigated the determi...

    Authors: Aleksandra Sobota and Gozde Ozakinci

    Citation: BMC Cancer 2018 18:874

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  44. Content type: Study protocol

    Anthracycline chemotherapy agents are commonly used to treat breast cancer, but also result in cardiac injury, and potentially detrimental effects to vascular and skeletal muscle. Preclinical evidence demonstr...

    Authors: Amy A. Kirkham, D. Ian Paterson, Carla M. Prado, John M. Mackey, Kerry S. Courneya, Edith Pituskin and Richard B. Thompson

    Citation: BMC Cancer 2018 18:864

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    The Correction to this article has been published in BMC Cancer 2019 19:75

  45. Content type: Study protocol

    Breast cancer (BC) is the most frequent cancer in women with more than 70% of BC patients being treated with hormonal therapy (HT). Among these patients, some report difficulties in remembering what they are s...

    Authors: Mylène Duivon, Joy Perrier, Florence Joly, Idlir Licaj, Jean-Michel Grellard, Bénédicte Clarisse, Christelle Lévy, Philippe Fleury, Sophie Madeleine, Nicolas Lefèvre, Géraldine Rauchs, Grégory Lecouvey, Florence Fraisse, Fausto Viader, Francis Eustache, Béatrice Desgranges…

    Citation: BMC Cancer 2018 18:866

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  46. Content type: Study protocol

    Routine assessment and clinical utilisation of patient-reported outcome (PRO) measures can lead to improved patient outcomes. The PROMPT-Care eHealth system facilitates PRO data capture from cancer patients, d...

    Authors: Afaf Girgis, Ivana Durcinoska, Martha Gerges, Nasreen Kaadan, Anthony Arnold, Joseph Descallar and Geoff P. Delaney

    Citation: BMC Cancer 2018 18:845

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  47. Content type: Study protocol

    Treatments for localized prostate cancer present challenging tradeoffs in the face of uncertain treatment benefits. These options are best weighed in a process of shared decision-making with the patient’s heal...

    Authors: Joel E. Pacyna, Simon Kim, Kathleen Yost, Hillary Sedlacek, Daniel Petereit, Judith Kaur, Bruce Rapkin, Robert Grubb, Electra Paskett, George J. Chang, Jeff Sloan, Ethan Basch, Brittny Major, Paul Novotny, John Taylor, Jan Buckner…

    Citation: BMC Cancer 2018 18:788

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  48. Content type: Study protocol

    Individual patients differ in their psychological response when receiving a cancer diagnosis, in this case breast cancer. Given the same disease burden, some patients master the situation well, while others ex...

    Authors: Ulrika Axelsson, Lisa Rydén, Per Johnsson, Patrik Edén, Johanna Månsson, Ingalill Rahm Hallberg and Carl A. K. Borrebaeck

    Citation: BMC Cancer 2018 18:789

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  49. Content type: Study protocol

    Cancer-related fatigue (CRF) is a common and distressing symptom of cancer and/or cancer treatment that persists for years after treatment completion in approximately one third of cancer survivors. Exercise is...

    Authors: Rosie Twomey, Tristan Martin, John Temesi, S. Nicole Culos-Reed and Guillaume Y. Millet

    Citation: BMC Cancer 2018 18:757

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