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Supportive therapy, survivorship and psychosocial oncology

This section focuses on clinical research in the field of supportive therapy for short and long term effects (including emesis, pain, bone metastases, orphan symptoms, simultaneous care, elderly, comorbidities, emerging toxicities induced by innovative drugs, etc) induced by cancer therapies, along with their impact on quality of life, survivorship and well-being. This section will also consider material on the field of precision medicine in supportive therapy, but also on patient care and psychosocial oncology.

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  1. Content type: Research article

    Individuals with cancer have reduced quality of life, functionality, range of motion, strength, and an increase in pain and fatigue. Exergaming appears to be an effective rehabilitation tool for Parkinson’s di...

    Authors: Daniel Tough, Jonathan Robinson, Steven Gowling, Peter Raby, John Dixon and Samantha L. Harrison

    Citation: BMC Cancer 2018 18:1151

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  2. Content type: Study protocol

    African American adults experience a disproportionate burden and increased mortality for most solid tumor cancers and their adolescent children are negatively impacted by the illness experience. The purpose of...

    Authors: Nicole S. McKinney, Shannon Virtue, Frances Marcus Lewis, Alliric I. Willis, Tanisha Pettyjohn, La-Rhonda Harmon and Adam Davey

    Citation: BMC Cancer 2018 18:1140

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  3. Content type: Research article

    Outpatient autologous stem cell transplantations (ASCTs) in multiple myeloma and lymphoma patients have been shown to reduce the overall costs and improve the quality of life relative to inpatient ASCTs. This ...

    Authors: Weerapat Owattanapanich, Kittima Suphadirekkul, Chutima Kunacheewa, Patompong Ungprasert and Kannadit Prayongratana

    Citation: BMC Cancer 2018 18:1126

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  4. Content type: Study protocol

    Cancer has a lot of consequences on patients’ quality of life (such as cancer-related fatigue (CRF), sleep difficulties and emotional distress) and on patients’ partners and their relationship, such as distres...

    Authors: Charlotte Grégoire, Marie-Elisabeth Faymonville, Audrey Vanhaudenhuyse, Vanessa Charland-Verville, Guy Jerusalem and Isabelle Bragard

    Citation: BMC Cancer 2018 18:1113

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  5. Content type: Research article

    Given the high cure-rate for testicular cancer (TC) and the patients’ young age, comprehensive evaluation of health-related quality of life (HRQOL) is an important consideration in this patient population. The...

    Authors: Monika Sztankay, Neil K. Aaronson, Juan I. Arraras, Umberto Basso, Uros Bumbasirevic, Fabio Efficace, Johannes M. Giesinger, Colin D. Johnson, Marieke van Leeuwen, Anne S. Oberguggenberger, Roman Sosnowski, Teresa Young and Bernhard Holzner

    Citation: BMC Cancer 2018 18:1104

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  6. Content type: Research article

    Utility weight, a measure of health-related quality of life, is used in disease burden measurements and economic evaluations. In this study, we used the visual analogue scale (VAS) and standard gamble (SG) met...

    Authors: Eun-Jung Kim, Minsu Ock, Kyu-pyo Kim, Nuri Hyun Jung, Hyeon-Jeong Lee, Seon-Ha Kim and Min-Woo Jo

    Citation: BMC Cancer 2018 18:1081

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  7. Content type: Study protocol

    Health service change is difficult to achieve. One strategy to facilitate such change is the clinical pathway, a guide for clinicians containing a defined set of evidence-based interventions for a specific con...

    Authors: Phyllis Butow, Joanne Shaw, Heather L. Shepherd, Melanie Price, Lindy Masya, Brian Kelly, Nicole M. Rankin, Afaf Girgis, Thomas F. Hack, Philip Beale, Rosalie Viney, Haryana M. Dhillon, Joseph Coll, Patrick Kelly, Melanie Lovell, Peter Grimison…

    Citation: BMC Cancer 2018 18:1077

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  8. Content type: Study protocol

    Up to 80% of breast cancer patients suffer from Cancer Related Cognitive Impairments (CRCI). Exercise is suggested as a potential supportive care option to reduce cognitive decline in cancer patients. This stu...

    Authors: Max Oberste, Nils Schaffrath, Katharina Schmidt, Wilhelm Bloch, Elke Jäger, Karen Steindorf, Philipp Hartig, Niklas Joisten and Philipp Zimmer

    Citation: BMC Cancer 2018 18:1071

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  9. Content type: Study protocol

    Higher levels of physical activity (PA) after treatment are associated with beneficial effects on physical and psychosocial functioning of cancer survivors. However, survivors often do not meet the recommended...

    Authors: H. J. van de Wiel, M. M. Stuiver, A. M. May, S. van Grinsven, N. K. Aaronson, V. P. Retèl, H. S. A. Oldenburg, H. G. van der Poel, S. Horenblas, W. H. van Harten and W. G. Groen

    Citation: BMC Cancer 2018 18:1073

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  10. Content type: Research article

    A patient’s physical function plays a leading role in the treatment prescription for patients with cancer. Objective assessments of physical function may be more predictive for treatment tolerability and survi...

    Authors: Joeri A. J. Douma, Henk M. W. Verheul and Laurien M. Buffart

    Citation: BMC Cancer 2018 18:1052

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  11. Content type: Study protocol

    Androgen deprivation therapy (ADT) is commonly used to treat prostate cancer. However, side effects of ADT often lead to reduced quality of life and physical function. Existing evidence demonstrates that exerc...

    Authors: Shabbir M. H. Alibhai, Paul Ritvo, Daniel Santa Mina, Catherine Sabiston, Murray Krahn, George Tomlinson, Andrew Matthew, Himu Lukka, Padraig Warde, Sara Durbano, Meagan O’Neill and S. Nicole Culos-Reed

    Citation: BMC Cancer 2018 18:1031

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  12. Content type: Research article

    How patients recover and resume everyday life after curative hepato-pancreato-biliary (HPB) surgery with intestinal reconstruction has, to our knowledge, not previously been investigated. We wanted to explore ...

    Authors: Kristine Elberg Dengsø, Tine Tjørnhøj-Thomsen, Susanne Oksbjerg Dalton, Bo Marcel Christensen, Jens Hillingsø and Thordis Thomsen

    Citation: BMC Cancer 2018 18:1017

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  13. Content type: Research article

    Colorectal cancer is a significant issue internationally, with over 1.3 million people diagnosed annually. Survival rates are increasing as treatments improve, although physical symptoms can persist despite er...

    Authors: Claire O’Gorman, Jim Stack, Alan O’Ceilleachair, Suzanne Denieffe, Martina Gooney, Martina McKnight and Linda Sharp

    Citation: BMC Cancer 2018 18:1022

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  14. Content type: Research article

    Fear of cancer recurrence (FCR) has been shown to be higher in patients treated with external beam radiotherapy (RT) compared to those untreated. However, little is known about the dynamics of patient’s FCR du...

    Authors: Y. Yang, J. Cameron, C. Bedi and G. Humphris

    Citation: BMC Cancer 2018 18:1002

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  15. Content type: Research article

    Decrease in bone mineral density, osteoporosis development, bone toxicity and resulting insufficiency fractures as late effect of radiotherapy are not well known. Osteoporosis development related to radiothera...

    Authors: Gokhan Yaprak, Cengiz Gemici, Sule Temizkan, Sevim Ozdemir, Berfu Cinkit Dogan and Ozgur Ozan Seseogullari

    Citation: BMC Cancer 2018 18:972

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  16. Content type: Research article

    Paclitaxel induced peripheral neuropathy (PIPN) is a major debilitating side effect of paclitaxel in patients with breast cancer with no fully known mechanisms. The aim of the study was to find out the possibl...

    Authors: Zohreh Ghoreishi, Seyedali Keshavarz, Mohammad Asghari Jafarabadi, Zahra Fathifar, Karyn A Goodman and Ali Esfahani

    Citation: BMC Cancer 2018 18:958

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  17. Content type: Research article

    Patients’ quality of life has become a major objective of care in oncology. At the same time, it has become the object of increasing interest by researchers, working with both quantitative and qualitative meth...

    Authors: Jordan Sibeoni, Camille Picard, Massimiliano Orri, Mathilde Labey, Guilhem Bousquet, Laurence Verneuil and Anne Revah-Levy

    Citation: BMC Cancer 2018 18:951

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  18. Content type: Study protocol

    Many studies have shown that lifestyle factors such as diet, physical activity are related to the incidence of cancer. However, there are few studies on the association between lifestyle factors and cancer pro...

    Authors: Yuri Mizota, Yukihide Kanemitsu, Shunsuke Tsukamoto, Dai Shida, Hiroki Ochiai and Seiichiro Yamamoto

    Citation: BMC Cancer 2018 18:953

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  19. Content type: Study protocol

    Several intervention studies have demonstrated that exercise training has beneficial effects among cancer patients. However, older cancer patients are underrepresented in clinical trials, and only few exercise...

    Authors: Marta Kramer Mikkelsen, Cecilia Margareta Lund, Anders Vinther, Anders Tolver, Anne-Mette Ragle, Julia Sidenius Johansen, Inna Chen, Lotte Engell-Noerregaard, Finn Ole Larsen, Bo Zerahn, Dorte Lisbet Nielsen and Mary Jarden

    Citation: BMC Cancer 2018 18:934

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  20. Content type: Research article

    Hospitalized cancer patients undergoing intensive or high-dose chemotherapy often experience a considerable decline in functional performance associated with the increased risk of adverse health events. Exerci...

    Authors: Antonia Pahl, Anja Wehrle, Sarah Kneis, Albert Gollhofer and Hartmut Bertz

    Citation: BMC Cancer 2018 18:920

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  21. Content type: Study protocol

    Patients undergoing chemotherapy are highly burdened by side effects. These may be caused by the pharmacodynamics of the drug or be driven by psychological factors such as negative expectations or pre-conditio...

    Authors: Julia Quidde, Yiqi Pan, Melanie Salm, Armin Hendi, Sven Nilsson, Karin Oechsle, Alexander Stein and Yvonne Nestoriuc

    Citation: BMC Cancer 2018 18:916

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  22. Content type: Research article

    Women diagnosed with gynaecological cancer experience supportive care needs that require care provision to reduce the impact on their lives. International evidence suggests supportive care needs of women with ...

    Authors: Natalie Williams, Georgia Griffin, Victoria Farrell, Alethea Rea, Kevin Murray and Yvonne L. Hauck

    Citation: BMC Cancer 2018 18:912

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  23. Content type: Research article

    Physical exercise and nutritional treatment are promising measures to prevent muscle wasting that is frequently observed in advanced-stage cancer patients. However, conventional exercise is not always suitable...

    Authors: Kristin Schink, Hans J. Herrmann, Raphaela Schwappacher, Julia Meyer, Till Orlemann, Elisabeth Waldmann, Bernd Wullich, Andreas Kahlmeyer, Rainer Fietkau, Dorota Lubgan, Matthias W. Beckmann, Carolin Hack, Wolfgang Kemmler, Jürgen Siebler, Markus F. Neurath and Yurdagül Zopf

    Citation: BMC Cancer 2018 18:886

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  24. Content type: Study protocol

    Cancer related fatigue (CRF) is one of the most prevalent and distressing long-term complaints reported by (non-) Hodgkin survivors. To date there has been no standard treatment for CRF in this population. A n...

    Authors: Daniëlle E. J. Starreveld, Laurien A. Daniels, Heiddis B. Valdimarsdottir, William H. Redd, Jessie L. de Geus, Sonia Ancoli-Israel, Susan Lutgendorf, Catharina M. Korse, Jacobien M. Kieffer, Flora E. van Leeuwen and Eveline M. A. Bleiker

    Citation: BMC Cancer 2018 18:880

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  25. Content type: Research article

    Although there is a recognition of the importance of fertility to young women with cancer, we do not know who is at risk of distress related to fertility issues following diagnosis. We investigated the determi...

    Authors: Aleksandra Sobota and Gozde Ozakinci

    Citation: BMC Cancer 2018 18:874

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  26. Content type: Study protocol

    Anthracycline chemotherapy agents are commonly used to treat breast cancer, but also result in cardiac injury, and potentially detrimental effects to vascular and skeletal muscle. Preclinical evidence demonstr...

    Authors: Amy A. Kirkham, D. Ian Paterson, Carla M. Prado, John M. Mackey, Kerry S. Courneya, Edith Pituskin and Richard B. Thompson

    Citation: BMC Cancer 2018 18:864

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  27. Content type: Study protocol

    Breast cancer (BC) is the most frequent cancer in women with more than 70% of BC patients being treated with hormonal therapy (HT). Among these patients, some report difficulties in remembering what they are s...

    Authors: Mylène Duivon, Joy Perrier, Florence Joly, Idlir Licaj, Jean-Michel Grellard, Bénédicte Clarisse, Christelle Lévy, Philippe Fleury, Sophie Madeleine, Nicolas Lefèvre, Géraldine Rauchs, Grégory Lecouvey, Florence Fraisse, Fausto Viader, Francis Eustache, Béatrice Desgranges…

    Citation: BMC Cancer 2018 18:866

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  28. Content type: Study protocol

    Routine assessment and clinical utilisation of patient-reported outcome (PRO) measures can lead to improved patient outcomes. The PROMPT-Care eHealth system facilitates PRO data capture from cancer patients, d...

    Authors: Afaf Girgis, Ivana Durcinoska, Martha Gerges, Nasreen Kaadan, Anthony Arnold, Joseph Descallar and Geoff P. Delaney

    Citation: BMC Cancer 2018 18:845

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  29. Content type: Study protocol

    Treatments for localized prostate cancer present challenging tradeoffs in the face of uncertain treatment benefits. These options are best weighed in a process of shared decision-making with the patient’s heal...

    Authors: Joel E. Pacyna, Simon Kim, Kathleen Yost, Hillary Sedlacek, Daniel Petereit, Judith Kaur, Bruce Rapkin, Robert Grubb, Electra Paskett, George J. Chang, Jeff Sloan, Ethan Basch, Brittny Major, Paul Novotny, John Taylor, Jan Buckner…

    Citation: BMC Cancer 2018 18:788

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  30. Content type: Study protocol

    Individual patients differ in their psychological response when receiving a cancer diagnosis, in this case breast cancer. Given the same disease burden, some patients master the situation well, while others ex...

    Authors: Ulrika Axelsson, Lisa Rydén, Per Johnsson, Patrik Edén, Johanna Månsson, Ingalill Rahm Hallberg and Carl A. K. Borrebaeck

    Citation: BMC Cancer 2018 18:789

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  31. Content type: Study protocol

    Cancer-related fatigue (CRF) is a common and distressing symptom of cancer and/or cancer treatment that persists for years after treatment completion in approximately one third of cancer survivors. Exercise is...

    Authors: Rosie Twomey, Tristan Martin, John Temesi, S. Nicole Culos-Reed and Guillaume Y. Millet

    Citation: BMC Cancer 2018 18:757

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  32. Content type: Research article

    This prospective multicentre-study aimed to analyze return to work (RTW) among prostate cancer survivors 12 months after having attended a cancer rehabilitation program and to identify risk factors for no and ...

    Authors: Anneke Ullrich, Hilke Maria Rath, Ullrich Otto, Christa Kerschgens, Martin Raida, Christa Hagen-Aukamp and Corinna Bergelt

    Citation: BMC Cancer 2018 18:751

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  33. Content type: Study protocol

    Despite the significant, empirically supported benefits of physical activity, the majority of breast cancer survivors do not meet recommended guidelines for physical activity. A variety of effective strategies...

    Authors: Chad D. Rethorst, Heidi A. Hamann, Thomas J. Carmody, Kendall J. Sharp, Keith E. Argenbright, Barbara B. Haley, Celette Sugg Skinner and Madhukar H. Trivedi

    Citation: BMC Cancer 2018 18:744

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  34. Content type: Research article

    Adjuvant endocrine therapy (AET) significantly decreases the risk of breast cancer recurrence and mortality. Notwithstanding the demonstrated efficacy of AET, 31–73% of breast cancer survivors do not persist w...

    Authors: Leah K. Lambert, Lynda G. Balneaves, A. Fuchsia Howard, Stephen K. Chia and Carolyn C. Gotay

    Citation: BMC Cancer 2018 18:732

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  35. Content type: Study protocol

    A major challenge for those living with cancers of the upper gastrointestinal tract (oesophagus, stomach and pancreas), is the impact of the disease and treatment on nutritional status and quality of life. People...

    Authors: Lauren Hanna, Catherine E. Huggins, Kate Furness, Mary Anne Silvers, June Savva, Helena Frawley, Daniel Croagh, Paul Cashin, Liang Low, Judith Bauer, Helen Truby and Terrence Haines

    Citation: BMC Cancer 2018 18:707

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  36. Content type: Research article

    The insurance reimbursement rate of medical cost affects the quality and quantity of health services provided in China. The nature of this relationship, however, has not been reliably described in the field of...

    Authors: Xi Li, Qi Zhou, Xinyu Wang, Shaofei Su, Meiqi Zhang, Hao Jiang, Jiaying Wang and Meina Liu

    Citation: BMC Cancer 2018 18:683

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  37. Content type: Research article

    Evidence suggests reallocating daily sedentary time to physical activity or sleep confers important health benefits in cancer survivors. Despite emerging research suggesting physical activity as a treatment fo...

    Authors: Diane K. Ehlers, Jason Fanning, Elizabeth A. Salerno, Susan Aguiñaga, Josh Cosman, Joan Severson, Arthur F. Kramer and Edward McAuley

    Citation: BMC Cancer 2018 18:685

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  38. Content type: Research article

    Prostate and breast cancer can have a lot of negative consequences such as fatigue, sleep difficulties and emotional distress, which decrease quality of life. Group interventions showed benefits to emotional d...

    Authors: C. Grégoire, H. Nicolas, I. Bragard, F. Delevallez, I. Merckaert, D. Razavi, D. Waltregny, M.-E. Faymonville and A. Vanhaudenhuyse

    Citation: BMC Cancer 2018 18:677

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  39. Content type: Research article

    Adolescent and young adults (AYA) enrolment rates into cancer clinical trials (CCT) are the lowest of any age group globally. As AYA have distinct biological, psychosocial and relational needs, we aimed to exp...

    Authors: Jennifer A.H. Bell, Victoria Forcina, Laura Mitchell, Seline Tam, Kate Wang, Abha A. Gupta and Jeremy Lewin

    Citation: BMC Cancer 2018 18:629

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  40. Content type: Research article

    Inter-patient variability in response to opioids is well known but a comprehensive definition of its pathophysiological mechanism is still lacking and, more importantly, no studies have focused on children. Th...

    Authors: Ersilia Lucenteforte, Laura Vagnoli, Alessandra Pugi, Giada Crescioli, Niccolò Lombardi, Roberto Bonaiuti, Maurizio Aricò, Sabrina Giglio, Andrea Messeri, Alessandro Mugelli, Alfredo Vannacci and Valentina Maggini

    Citation: BMC Cancer 2018 18:568

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  41. Content type: Research article

    Management of squamous cell carcinoma of the anus (SCCA) is becoming more relevant, as its incidence increases. The purpose of this study was to investigate possible differences in patient population and care ...

    Authors: Victor E. Pricolo, Matteo Bonvini and Carlo F. Abelli

    Citation: BMC Cancer 2018 18:567

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  42. Content type: Research article

    Nausea/vomiting (N/V) not related to anti-cancer treatment is common in patients with advanced cancer. The standard approach to management is to define a dominant cause, and treat with an antiemetic selected t...

    Authors: Janet Hardy, Helen Skerman, Paul Glare, Jennifer Philip, Peter Hudson, Geoffrey Mitchell, Peter Martin, Odette Spruyt, David Currow and Patsy Yates

    Citation: BMC Cancer 2018 18:510

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  43. Content type: Study protocol

    Advanced cancer significantly impacts quality of life of patients and families as they cope with symptom burden, treatment decision-making, uncertainty and costs of treatment. In Singapore, information about t...

    Authors: Irene Teo, Ratna Singh, Chetna Malhotra, Semra Ozdemir, Rebecca A. Dent, Nesaretnam Barr Kumarakulasinghe, Wee Lee Yeo, Yin Bun Cheung, Rahul Malhotra, Ravindran Kanesvaran, Alethea Chung Pheng Yee, Noreen Chan, Huei Yaw Wu, Soh Mun Chin, Hum Yin Mei Allyn, Grace Meijuan Yang…

    Citation: BMC Cancer 2018 18:459

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  44. Content type: Study protocol

    The consequences of treatment for Head and Neck cancer (HNC) patients has profound detrimental impacts such as impaired QOL, emotional distress, delayed recovery and frequent use of healthcare. The aim of this...

    Authors: Simon N. Rogers, Derek Lowe, Cher Lowies, Seow Tien Yeo, Christine Allmark, Dominic Mcavery, Gerald M. Humphris, Robert Flavel, Cherith Semple, Steven J. Thomas and Anastasios Kanatas

    Citation: BMC Cancer 2018 18:444

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  45. Content type: Research article

    The increasing incidence of colorectal cancer in Taiwan has generated a need for a disease-specific quality-of-life measuring instrument. We aimed to validate the Taiwan Chinese version of the European Organis...

    Authors: Ming-Hung Shen, Ling-Ping Chen, Thien-Fiew Ho, Ying-Yih Shih, Ching-Shui Huang, Wei-Chu Chie and Chi-Cheng Huang

    Citation: BMC Cancer 2018 18:353

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  46. Content type: Study protocol

    Brief interventions for smoking cessation and alcohol moderation may contribute considerably to the prevention of cancer among populations at risk, such as cancer survivors, in addition to improving their gene...

    Authors: Ajla Mujcic, Matthijs Blankers, Brigitte Boon, Rutger Engels and Margriet van Laar

    Citation: BMC Cancer 2018 18:364

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  47. Content type: Research article

    The intent of this pooled analysis as part of the German society for radiation oncology (DEGRO) stereotactic body radiotherapy (SBRT) initiative was to analyze the patterns of care of SBRT for liver oligometas...

    Authors: N. Andratschke, H. Alheid, M. Allgäuer, G. Becker, O. Blanck, J. Boda-Heggemann, T. Brunner, M. Duma, S. Gerum, M. Guckenberger, G. Hildebrandt, R. J. Klement, V. Lewitzki, C. Ostheimer, A. Papachristofilou, C. Petersen…

    Citation: BMC Cancer 2018 18:283

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