Skip to main content

Medical and radiation oncology

Section edited by Dirk Vordermark

This section focuses on clinical research that impacts on the treatment of cancer using systemic chemotherapy, targeted therapy, and radiation.

Page 4 of 24

  1. Radiotherapy is known to improve local tumor control in locally advanced pancreatic cancer (LAPC), although there is a lack of convincing data on a potential overall survival benefit of chemoradiotherapy over ...

    Authors: Jakob Liermann, Patrick Naumann, Adriane Hommertgen, Moritz Pohl, Meinhard Kieser, Juergen Debus and Klaus Herfarth

    Citation: BMC Cancer 2020 20:947

    Content type: Study protocol

    Published on:

  2. Undifferentiated carcinoma (UC) of the pancreas is a rare subtype of pancreatic cancer. Although UC has been considered a highly aggressive malignancy, no clinical studies have addressed the efficacy of chemot...

    Authors: Hiroshi Imaoka, Masafumi Ikeda, Kosuke Maehara, Kumiko Umemoto, Masato Ozaka, Satoshi Kobayashi, Takeshi Terashima, Hiroto Inoue, Chihiro Sakaguchi, Kunihiro Tsuji, Kazuhiko Shioji, Keiya Okamura, Yasuyuki Kawamoto, Rei Suzuki, Hirofumi Shirakawa, Hiroaki Nagano…

    Citation: BMC Cancer 2020 20:946

    Content type: Research article

    Published on:

  3. Hepatocellular carcinoma (HCC) is an inflammation-related cancer, where nonresolving inflammation contributes to its development and progression. Peripheral inflammatory cells have been shown to be associated ...

    Authors: Young Mi Hong, Ki Tae Yoon, Tae Ho Hwang and Mong Cho

    Citation: BMC Cancer 2020 20:937

    Content type: Research article

    Published on:

  4. Head and neck squamous cell cancer (HNSCC) frequently causes severe symptoms that may be reduced, when the tumor is successfully treated. The SOCCER trial studied the association of treatment response with pat...

    Authors: Markus Hecht, Dennis Hahn, Philipp Wolber, Matthias G. Hautmann, Dietmar Reichert, Steffi Weniger, Claus Belka, Tobias Bergmann, Thomas Göhler, Manfred Welslau, Christina Große-Thie, Orlando Guntinas-Lichius, Jens von der Grün, Panagiotis Balermpas, Katrin Orlowski, Diethelm Messinger…

    Citation: BMC Cancer 2020 20:933

    Content type: Research article

    Published on:

  5. Internal mammary and/or supraclavicular (IM–SC) lymph node (LN) recurrence without distant metastasis (DM) in patients with breast cancer is rare, and there have been few reports on its clinical outcomes.

    Authors: Hitoshi Inari, Natsuki Teruya, Miki Kishi, Rie Horii, Futoshi Akiyama, Shunji Takahashi, Yoshinori Ito, Takayuki Ueno, Takuji Iwase and Shinji Ohno

    Citation: BMC Cancer 2020 20:932

    Content type: Research article

    Published on:

  6. The incidence of oropharyngeal squamous cell carcinoma (OPSCC) in the US is rapidly increasing, driven largely by the epidemic of human papillomavirus (HPV)-mediated OPSCC. Although survival for patients with ...

    Authors: Hesham Elhalawani, Abdallah S. R. Mohamed, Baher Elgohari, Timothy A. Lin, Andrew G. Sikora, Stephen Y. Lai, Abdelrahman Abusaif, Jack Phan, William H. Morrison, G. Brandon Gunn, David I. Rosenthal, Adam S. Garden, Clifton D. Fuller and Vlad C. Sandulache

    Citation: BMC Cancer 2020 20:912

    Content type: Research article

    Published on:

  7. The prognosis of lung cancer was found to be associated with a series of biomarkers related to the tumor immune microenvironment (TIME), which can modulate the biological behaviors and consequent outcomes of l...

    Authors: Dantong Sun, Lu Tian, Tiantian Bian, Han Zhao, Junyan Tao, Lizong Feng, Qiaoling Liu and Helei Hou

    Citation: BMC Cancer 2020 20:910

    Content type: Research article

    Published on:

  8. High resolution melting curve analysis is a cost-effective rapid screening method for detection of somatic gene mutation. The performance characteristics of this technique has been explored previously, however...

    Authors: Reenu Anne Joy, Sukrishna Kamalasanan Thelakkattusserry, Narendranath Vikkath, Renjitha Bhaskaran, Sajitha Krishnan, Damodaran Vasudevan and Prasanth S. Ariyannur

    Citation: BMC Cancer 2020 20:902

    Content type: Research article

    Published on:

  9. Since the development of three-dimensional conformal radiotherapy and intensity-modulated radiotherapy (IMRT), no prospective study has investigated whether concurrent chemoradiotherapy (SIB-IMRT with 60 Gy) r...

    Authors: Lin-rui Gao, Xin Wang, Weiming Han, Wei Deng, Chen Li, Xiaomin Wang, Yidian Zhao, Wenjie Ni, Xiao Chang, Zongmei Zhou, Lei Deng, Wenqing Wang, Wenyang Liu, Jun Liang, Tao Zhang, Nan Bi…

    Citation: BMC Cancer 2020 20:901

    Content type: Study protocol

    Published on:

  10. The effect of brachytherapy on lymphocytes and cytokines in the tumor microenvironment is unclear. This study aimed to analyze the relationship between the invasion of lymphocytes and cytokines in the tumor mi...

    Authors: Lin Li, Hong Cheng Yue, Yun Wei Han, Wei Liu, Liang Geng Xiong and Jian Wen Zhang

    Citation: BMC Cancer 2020 20:893

    Content type: Research article

    Published on:

  12. In recent years, there is increasing evidence showing a beneficial outcome (e.g. progression free survival; PFS) after metastases-directed therapy (MDT) with external beam radiotherapy (EBRT) or targeted surge...

    Authors: Bastiaan M. Privé, Marcel J. R. Janssen, Inge M. van Oort, Constantijn H. J. Muselaers, Marianne A. Jonker, Michel de Groot, Niven Mehra, J. Fred Verzijlbergen, Tom W. J. Scheenen, Patrik Zámecnik, Jelle O. Barentsz, Martin Gotthardt, Walter Noordzij, Wouter V. Vogel, Andries M. Bergman, Henk G. van der Poel…

    Citation: BMC Cancer 2020 20:884

    Content type: Study protocol

    Published on:

  13. Currently, adjuvant therapy is not recommended for patients with thoracic esophageal squamous cell cancer (TESCC) after radical surgery, and a proportion of these patients go on to develop locoregional recurre...

    Authors: Xiao Chang, Lei Deng, Wenjie Ni, Chen Li, Weiming Han, Lin-rui Gao, Shijia Wang, Zongmei Zhou, Dongfu Chen, Qinfu Feng, Jun Liang, Nan Bi, Jima Lv, Shugeng Gao, Yousheng Mao, Qi Xue…

    Citation: BMC Cancer 2020 20:877

    Content type: Study protocol

    Published on:

  14. 5α-reductase inhibitors (5-ARIs) inhibit the pathway of converting the testosterone to dihydrotestosterone and are widely used in benign prostatic hyperplasia patients. Since androgen receptor activation may p...

    Authors: Chien-Sheng Wang, Ching-Chia Li, Yung-Shun Juan, Wen-Jeng Wu and Hsiang-Ying Lee

    Citation: BMC Cancer 2020 20:872

    Content type: Research article

    Published on:

  16. Endometrial cancer, one of the most common malignant tumors, is a serious threat to women’s health. Endometrial hyperplasia is a precursor of endometrial cancer. S100 calcium binding protein P (S100P) has been...

    Authors: Dan Zhang, Xiuying Chen, Hexia Xia, Lu Wang, Hongbo Zhao, Bufang Xu, Aijun Zhang and Wei Zhang

    Citation: BMC Cancer 2020 20:845

    Content type: Research article

    Published on:

  17. In 1997, the Radiation Therapy Oncology Group (RTOG) put forward the recursive partitioning analysis classification for the prognosis of brain metastases (BMs), but this system does not take into account the epid...

    Authors: Jing Wang, Zhiyan Liu, Qingsong Pang, Tian Zhang, Xi Chen, Puchun Er, Yuwen Wang, Ping Wang and Jun Wang

    Citation: BMC Cancer 2020 20:837

    Content type: Research article

    Published on:

  18. Phase 3 studies suggest that induction chemotherapy (ICT) of cisplatin and 5-fluorouracil plus docetaxel (TPF) is effective but toxic for patients with squamous-cell carcinoma of the head and neck (SCCHN). Dos...

    Authors: Ching-Yun Hsieh, Ming-Yuh Lein, Shih-Neng Yang, Yao-Ching Wang, Yin-Jun Lin, Chen-Yuan Lin, Chun-Hung Hua, Ming-Hsul Tsai and Ching-Chan Lin

    Citation: BMC Cancer 2020 20:832

    Content type: Research article

    Published on:

  19. Current standard practice for locally advanced rectal cancer (LARC) entails a multidisciplinary approach that includes preoperative chemoradiotherapy, followed by total mesorectal excision, and then adjuvant c...

    Authors: Ali Shamseddine, Youssef H. Zeidan, Malek Kreidieh, Ibrahim Khalifeh, Rim Turfa, Joseph Kattan, Deborah Mukherji, Sally Temraz, Kholoud Alqasem, Rula Amarin, Tala Al Awabdeh, Samer Deeba, Faek Jamali, Issa Mohamad, Mousa Elkhaldi, Faiez Daoud…

    Citation: BMC Cancer 2020 20:831

    Content type: Study protocol

    Published on:

  20. Peritoneal metastasis is the most frequent failure in gastric cancer. This study evaluated the role of prophylactic chemotherapeutic hyperthermic intraperitoneal perfusion (CHIP) in patients after D2 dissection.

    Authors: Lucheng Zhu, Zhizheng Xu, Yajun Wu, Pengyuan Liu, Jianing Qian, Shuhuan Yu, Bing Xia, Jianjun Lai, Shenglin Ma and Zhibing Wu

    Citation: BMC Cancer 2020 20:827

    Content type: Research article

    Published on:

  21. FOLFOXIRI (fluorouracil, leucovorin, oxaliplatin, and irinotecan) plus bevacizumab has shown to be one of the therapeutic regimens in first line with the highest activity in patients (pts.) with metastatic col...

    Authors: Angela Damato, Francesco Iachetta, Lorenzo Antonuzzo, Guglielmo Nasti, Francesca Bergamo, Roberto Bordonaro, Evaristo Maiello, Alberto Zaniboni, Giuseppe Tonini, Alessandra Romagnani, Annalisa Berselli, Nicola Normanno and Carmine Pinto

    Citation: BMC Cancer 2020 20:822

    Content type: Study protocol

    Published on:

  22. Differentiation syndrome (DS) is the main life-threatening adverse event that occurs in acute promyelocytic leukemia (APL) patients treated with all-trans retinoic acid (ATRA). Cytokine imbalances have been re...

    Authors: Luciana Yamamoto de Almeida, Diego Antonio Pereira-Martins, Ana Sílvia Gouvêa Lima, Márcia Sueli Baggio, Luisa Corrêa de Araujo Koury, Ana Paula Lange, Sarah Cristina Bassi, Priscila Santos Scheucher and Eduardo Magalhães Rego

    Citation: BMC Cancer 2020 20:821

    Content type: Research article

    Published on:

  23. Recently, copy number alteration (CNA) of 9p24.1 were demonstrated in 10% of diffuse large b-cell lymphoma (DLBCL), with gene expression and mutation profiles that were similar to those of primary mediastinal ...

    Authors: Xuemin Xue, Wenting Huang, Tian Qiu, Lei Guo, Jianming Ying and Ning Lv

    Citation: BMC Cancer 2020 20:816

    Content type: Research article

    Published on:

  24. By investigating treatment patterns and outcomes in locally advanced head and neck squamous cell carcinoma (LA-HNSCC), we aimed at providing valuable insights into the optimal therapeutic strategy for physicia...

    Authors: Yun-Gyoo Lee, Eun Joo Kang, Bhumsuk Keam, Jin-Hyuk Choi, Jin-Soo Kim, Keon Uk Park, Kyoung Eun Lee, Jung Hye Kwon, Keun-Wook Lee, Min Kyoung Kim, Hee Kyung Ahn, Seong Hoon Shin, Hye Ryun Kim, Sung-Bae Kim and Hwan Jung Yun

    Citation: BMC Cancer 2020 20:813

    Content type: Research article

    Published on:

  25. The aim of this study was to investigate the optimal order of radiation therapy in patients affected by stage IIIA pathologic N2 (IIIA/N2) non-small-cell lung cancer (NSCLC) and to identify its potential risk ...

    Authors: Hongxia Duan, Long Liang, Shuanshuan Xie and Changhui Wang

    Citation: BMC Cancer 2020 20:809

    Content type: Research article

    Published on:

  26. Non-small cell lung cancer is the most common cause of cancer death worldwide, highlighting the need for novel therapeutic concepts. In particular, there is still a lack of treatment strategies for the group o...

    Authors: Farastuk Bozorgmehr, Inn Chung, Petros Christopoulos, Johannes Krisam, Marc A. Schneider, Lena Brückner, Daniel Wilhelm Mueller, Michael Thomas and Stefan Rieken

    Citation: BMC Cancer 2020 20:806

    Content type: Study protocol

    Published on:

  27. Recently, the endothelial Activation and Stress Index (EASIX) score has been reported to predict overall survival (OS) after allogeneic stem cell transplantation. This study evaluated the prognostic role of EA...

    Authors: Ga-Young Song, Sung-Hoon Jung, Kihyun Kim, Seok Jin Kim, Sang Eun Yoon, Ho Sup Lee, Mihee Kim, Seo-Yeon Ahn, Jae-Sook Ahn, Deok-Hwan Yang, Hyeoung-Joon Kim and Je-Jung Lee

    Citation: BMC Cancer 2020 20:803

    Content type: Research article

    Published on:

  28. The optimal chemotherapy regimen for treating HIV associated NHL in low resource settings is unknown. We conducted a retrospective study to describe survival rates, treatment response rates and adverse events ...

    Authors: Clement D. Okello, Abrahams Omoding, Henry Ddungu, Yusuf Mulumba and Jackson Orem

    Citation: BMC Cancer 2020 20:798

    Content type: Research article

    Published on:

  29. The role of post-mastectomy radiotherapy (PMRT) in the treatment of patients with T1–2N1 breast cancer is controversial. This study’s purpose was to evaluate the risk of recurrence of T1–2N1 breast cancer and ...

    Authors: Shulian Wang, Ge Wen, Yu Tang, Yong Yang, Hao Jing, Jianyang Wang, Jianghu Zhang, Xuran Zhao, Guangyi Sun, Jing Jin, Yongwen Song, Yueping Liu, Hui Fang, Yujing Zhang and Yexiong Li

    Citation: BMC Cancer 2020 20:792

    Content type: Research article

    Published on:

  30. Accurate detection of patients with minimal residual disease (MRD) after surgery for stage II colon cancer (CC) remains an urgent unmet clinical need to improve selection of patients who might benefit form adj...

    Authors: S. J. Schraa, K. L. van Rooijen, D. E. W. van der Kruijssen, C. Rubio Alarcón, J. Phallen, M. Sausen, J. Simmons, V. M. H. Coupé, W. M. U. van Grevenstein, S. Elias, H. M. Verkooijen, M. M. Laclé, L. J. W. Bosch, D. van den Broek, G. A. Meijer, V. E. Velculescu…

    Citation: BMC Cancer 2020 20:790

    Content type: Study protocol

    Published on:

  31. Meningiomas are the most common primary central nervous system tumors. Potential risk factors include obesity, height, history of allergy/atopy, and autoimmune diseases, but findings are conflicting. This stud...

    Authors: Matan Ben-Zion Berliner, Lior Haim Katz, Estela Derazne, Hagai Levine, Lital Keinan-Boker, Alexandra Benouaich-Amiel, Omer Gal, Andrew A Kanner, Yosef Laviv, Asaf Honig, Tali Siegal, Jacob Mandel, Gilad Twig and Shlomit Yust-Katz

    Citation: BMC Cancer 2020 20:786

    Content type: Research article

    Published on:

  32. Pneumonitis is a possible side effect of radiotherapy for lung cancer. Since it can occur up to several months following treatment, symptoms may not be associated with previous radiotherapy, and pneumonitis ca...

    Authors: Dirk Rades, Elisa Marie Werner, Esther Glatzel, Marie-Christine Eggert, Denise Olbrich, Soeren Tvilsted and Sabine Bohnet

    Citation: BMC Cancer 2020 20:785

    Content type: Study protocol

    Published on:

  33. BCD-022 is a trastuzumab biosimilar which was shown to be equivalent to reference trastuzumab in a wide panel of physicochemical studies as well as preclinical studies in vitro and in vivo. International multi...

    Authors: Sergey M. Alexeev, Andrey V. Khorinko, Guzel Z. Mukhametshina, Konstantin G. Shelepen, Olga N. Burdaeva, Sergey A. Kulik, Chiradoni Thugappa Satheesh, Kirti Srivastava, Mummaneni Vikranth, Fedor Kryukov, Anastasia N. Paltusova, Mariya S. Shustova and Roman A. Ivanov

    Citation: BMC Cancer 2020 20:783

    Content type: Research article

    Published on:

  34. It is estimated that around 15–30% of patients with early stage colon cancer benefit from adjuvant chemotherapy. We are currently not capable of upfront selection of patients who benefit from chemotherapy, whi...

    Authors: I. van den Berg, S. van de Weerd, J. M. L. Roodhart, G. R. Vink, R. R. J. Coebergh van den Braak, C. R. Jimenez, S. G. Elias, D. van Vliet, M. Koelink, E. Hong, W. M. U. van Grevenstein, M. G. H. van Oijen, R. G. H. Beets-Tan, J. H. J. M. van Krieken, J. N. M. IJzermans, J. P. Medema…

    Citation: BMC Cancer 2020 20:776

    Content type: Study protocol

    Published on:

  35. PARP inhibitors niraparib and talazoparib are FDA approved for special cases of breast cancer. PARP is an interesting repair protein which is frequently affected in cancer cells. We studied the combined action...

    Authors: Verena Weigert, Tina Jost, Markus Hecht, Ilka Knippertz, Lucie Heinzerling, Rainer Fietkau and Luitpold V. Distel

    Citation: BMC Cancer 2020 20:775

    Content type: Research article

    Published on:

  36. Medulloblastoma is extremely rare in adults. The role of chemotherapy for average-risk adult patients remains controversial. Surgery and radiotherapy provide a significant disease control and a good prognosis,...

    Authors: E. Franceschi, S. Minichillo, A. Mura, A. Tosoni, M. Mascarin, C. Tomasello, S. Bartolini and A. A. Brandes

    Citation: BMC Cancer 2020 20:755

    Content type: Research article

    Published on:

  37. Several studies have reported the incidence of interstitial pneumonia (IP) among patients with non-Hodgkin lymphoma (NHL) that are undergoing combination chemotherapy plus rituximab; however, the effective pro...

    Authors: Cong Li, Fangxiao Lu, Tao Lei, Haifeng Yu, Xi Chen, Shuailing Peng, Shuiyun Han and Haiyan Yang

    Citation: BMC Cancer 2020 20:742

    Content type: Research article

    Published on:

  38. Laryngocarcinoma (LC), in most cases a squamous cell carcinoma, accounts for 1 ~ 5% of the incidence of all tumors. At present, laryngocarcinoma is mainly managed with the integration of surgery and radio- and...

    Authors: Yining Yang, Li Li, Yongzhe Zheng, Qingfeng Liu, Xianfeng Wei, Xinyuan Gong, Wei Wang and Peng Lin

    Citation: BMC Cancer 2020 20:734

    Content type: Study protocol

    Published on:

  39. Risk stratification and prognosis prediction of acute myeloid leukemia (AML) are largely dependent on pre-treatment information. However, post-treatment data also provides much useful information. In this retr...

    Authors: Yang Wang, Hua Wang, Weida Wang, Wenjian Liu, Nawei Liu, Shuang Liu and Yue Lu

    Citation: BMC Cancer 2020 20:732

    Content type: Research article

    Published on:

  40. Primary surgery is usually the mainstay treatment in early-stage oropharyngeal and oral cavity cancer. Typically, neck surgery is performed. Negative tumor margins are recommended (> 5 mm). If feasible, re-res...

    Authors: Julian Biau, Emilie Thivat, Corinne Millardet, Nicolas Saroul, Nathalie Pham-Dang, Ioana Molnar, Bruno Pereira, Xavier Durando, Jean Bourhis and Michel Lapeyre

    Citation: BMC Cancer 2020 20:730

    Content type: Study protocol

    Published on:

  41. Anti-PD1 inhibitors have been approved for the treatment of recurrent or metastatic head and neck cancer (HNC), as a result of Global Phase III trials. However, the clinical outcomes of immune checkpoint inhib...

    Authors: Hyera Kim, Minsuk Kwon, Binnari Kim, Hyun Ae Jung, Jong-Mu Sun, Se-Hoon Lee, Keunchil Park and Myung-Ju Ahn

    Citation: BMC Cancer 2020 20:727

    Content type: Research article

    Published on:

  42. Splenic marginal zone lymphoma (SMZL) is a rare lymphoid B-cell malignant neoplasm with primary involvement of the spleen. It is a chronic disease, of indolent behavior and prolonged survival. However, 25% of ...

    Authors: Luís Alberto de Pádua Covas Lage, Felipe Faganelli Caboclo dos Santos, Débora Levy, Frederico Rafael Moreira, Samuel Campanelli Freitas Couto, Hebert Fabrício Culler, Renata de Oliveira Costa, Vanderson Rocha and Juliana Pereira

    Citation: BMC Cancer 2020 20:717

    Content type: Research article

    Published on:

  43. NSCLC patients with EGFR mutation were at a higher incidence of developing brain metastasis (BM). Patients with BM are associated with high mortality. Reducing BM incidence becomes increasingly significant for...

    Authors: Wen Ouyang, Jing Yu, Yan Zhou, Jing Hu, Zhao huang, Junhong Zhang and Conghua Xie

    Citation: BMC Cancer 2020 20:699

    Content type: Research article

    Published on:

  44. The evidence that albumin-bound paclitaxel (nab-paclitaxel) is safe and efficacious for the treatment of many types of malignant tumors is continuously increasing. However, the evidence and clinical data of na...

    Authors: Zhichao Tian, Fan Zhang, Po Li, Jiaqiang Wang, Jinpo Yang, Peng Zhang, Weitao Yao and Xin Wang

    Citation: BMC Cancer 2020 20:698

    Content type: Research article

    Published on:

  45. Craniospinal irradiation (CSI) of childhood tumors with the RapidArc technique is a new method of treatment. Our objective was to compare the acute hematological toxicity pattern during 3D conformal radiothera...

    Authors: Zoltán Lőcsei, Róbert Farkas, Kornélia Borbásné Farkas, Klára Sebestyén, Zsolt Sebestyén, Zoltán Musch, Ágnes Vojcek, Noémi Benedek, László Mangel and Gábor Ottóffy

    Citation: BMC Cancer 2020 20:702

    Content type: Research article

    Published on:

  46. For loco-regionally advanced, but transorally resectable oropharyngeal cancer (OPSCC), the current standard of care includes surgical resection and risk-adapted adjuvant (chemo) radiotherapy, or definite chemo...

    Authors: Lara Bußmann, Simon Laban, Claus Wittekindt, Carmen Stromberger, Silke Tribius, Nikolaus Möckelmann, Arne Böttcher, Christian Stephan Betz, Jens Peter Klussmann, Volker Budach, Adrian Muenscher and Chia-Jung Busch

    Citation: BMC Cancer 2020 20:701

    Content type: Study protocol

    Published on:

  47. Previous studies have shown that fibrinogen-to-albumin ratio (FAR) is a novel prognostic immune biomarker in various diseases. In this study, we investigated the role of FAR in the prognosis of patients with s...

    Authors: Qiang An, Wei Liu, Yujia Yang and Bing Yang

    Citation: BMC Cancer 2020 20:691

    Content type: Research article

    Published on:

  48. First-line treatment with FOLFOXIRI plus bevacizumab (BEV) is highly effective and regarded as one of the standards-of-care for patients with metastatic colorectal cancer (mCRC), despite the high incidence of ...

    Authors: Masaaki Miyo, Takeshi Kato, Takayuki Yoshino, Takeharu Yamanaka, Hideaki Bando, Hironaga Satake, Kentaro Yamazaki, Hiroya Taniguchi, Eiji Oki, Masahito Kotaka, Koji Oba, Yoshinori Miyata, Kei Muro, Yoshito Komatsu, Hideo Baba and Akihito Tsuji

    Citation: BMC Cancer 2020 20:687

    Content type: Study protocol

    Published on:

  49. Nivolumab has changed the treatment of advanced gastric cancer (AGC). Nivolumab shows better outcomes compared to best supportive care among AGC patients who received at least two prior regimens. However, ther...

    Authors: Toshihiko Matsumoto, Yosuke Yamamoto, Yusuke Kuriona, Ukyo Okazaki, Shogo Kimura, Kou Miura, Takao Tsuduki, Takanori Watanabe, Yusuke Mastumoto and Masahiro Takatani

    Citation: BMC Cancer 2020 20:684

    Content type: Research article

    Published on:

  50. Immune checkpoint inhibitors (ICIs) reported remarkable achievements in several solid tumours. However, in metastatic colorectal cancer (mCRC) promising results are limited to patients with deficient mismatch ...

    Authors: Carlotta Antoniotti, Beatrice Borelli, Daniele Rossini, Filippo Pietrantonio, Federica Morano, Lisa Salvatore, Sara Lonardi, Federica Marmorino, Stefano Tamberi, Salvatore Corallo, Giampaolo Tortora, Francesca Bergamo, Di Stefano Brunella, Alessandra Boccaccino, Elisa Grassi, Patrizia Racca…

    Citation: BMC Cancer 2020 20:683

    Content type: Study protocol

    Published on:

Submit manuscript

Follow

BMC Cancer

ISSN: 1471-2407

Contact us