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BMC Cancer

Medical and radiation oncology

Section edited by Dirk Vordermark

This section focuses on clinical research that impacts on the treatment of cancer using systemic chemotherapy, targeted therapy, and radiation.

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  1. Content type: Research article

    Preliminary evidence suggests that changes in plasma brain-derived neurotrophic factor (BDNF) levels may contribute to the occurrence of chemotherapy-associated cognitive impairment (CACI), and a previous stud...

    Authors: Terence Ng, Ying Yun Lee, Jung-woo Chae, Angie Hui Ling Yeo, Maung Shwe, Yan Xiang Gan, Raymond C. H. Ng, Pat Pak Yan Chu, Chiea Chuen Khor, Han Kiat Ho and Alexandre Chan

    Citation: BMC Cancer 2017 17:867

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  2. Content type: Case report

    Capecitabine is an oral prodrug of fluorouracil, which is a common agent used in the management of many solid tumor malignancies. Dermatologic reaction is common with various chemotherapy agents but is not com...

    Authors: Rena A. Shah, Daniel D. Bennett and Mark E. Burkard

    Citation: BMC Cancer 2017 17:866

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  3. Content type: Research article

    Compared with World Health Organization-defined acute myeloid leukaemia (AML) not otherwise specified, patients with AML with myelodysplasia-related changes (AML-MRC) are generally older and more likely to hav...

    Authors: John F. Seymour, Hartmut Döhner, Aleksandra Butrym, Agnieszka Wierzbowska, Dominik Selleslag, Jun Ho Jang, Rajat Kumar, James Cavenagh, Andre C. Schuh, Anna Candoni, Christian Récher, Irwindeep Sandhu, Teresa Bernal del Castillo, Haifa Kathrin Al-Ali, Jose Falantes, Richard M. Stone…

    Citation: BMC Cancer 2017 17:852

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  4. Content type: Study protocol

    In Japan, S-1 plus cisplatin (SP) regimen has become a standard therapy for patients with advanced gastric cancer. Moreover, the S-1 plus oxaliplatin regimen is now a standard treatment.

    Authors: Yasuyuki Kawamoto, Yoshito Komatsu, Satoshi Yuki, Kentaro Sawada, Tetsuhito Muranaka, Kazuaki Harada, Hiroshi Nakatsumi, Hiraku Fukushima, Atsushi Ishiguro, Masayoshi Dazai, Kazuteru Hatanaka, Michio Nakamura, Ichiro Iwanaga, Minoru Uebayashi, Susumu Sogabe, Yoshimitsu Kobayashi…

    Citation: BMC Cancer 2017 17:837

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  5. Content type: Research article

    To appraise the ability of a radiomics based analysis to predict local response and overall survival for patients with hepatocellular carcinoma.

    Authors: Luca Cozzi, Nicola Dinapoli, Antonella Fogliata, Wei-Chung Hsu, Giacomo Reggiori, Francesca Lobefalo, Margarita Kirienko, Martina Sollini, Davide Franceschini, Tiziana Comito, Ciro Franzese, Marta Scorsetti and Po-Ming Wang

    Citation: BMC Cancer 2017 17:829

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  6. Content type: Case report

    Leukocytoclastic vasculitis is typically mediated by deposition of immune complexes and is related to many causes, including medication. To the best of our knowledge, leukocytoclastic vasculitis related to cis...

    Authors: Júlia Coelho França Quintanilha, Marília Berlofa Visacri, Laís Sampaio Amaral, Carmen Silvia Passos Lima, Maria Letícia Cintra and Patricia Moriel

    Citation: BMC Cancer 2017 17:831

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  7. Content type: Research article

    The efficacy and safety of eribulin in patients with locally advanced or metastatic breast cancer has been demonstrated in phase III trials. However, as patients receiving eribulin in daily practice do not nec...

    Authors: Sakura Iizumi, Tatsunori Shimoi, Natsuko Tsushita, Seiko Bun, Akihiko Shimomura, Emi Noguchi, Makoto Kodaira, Mayu Yunokawa, Kan Yonemori, Chikako Shimizu, Yasuhiro Fujiwara and Kenji Tamura

    Citation: BMC Cancer 2017 17:819

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  8. Content type: Study protocol

    For metastatic spinal cord compression (MSCC), conventional radiotherapy with 10 × 3 Gy in 2 weeks results in better local progression-free survival (LPFS) than 5 × 4 Gy in 1 week. Since patients with MSCC are...

    Authors: Dirk Rades, Jon Cacicedo, Antonio J. Conde-Moreno, Claudia Doemer, Jürgen Dunst, Darejan Lomidze, Barbara Segedin, Denise Olbrich and Niels Henrik Holländer

    Citation: BMC Cancer 2017 17:818

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  9. Content type: Research article

    Médecins Sans Frontières is supporting comprehensive HIV care and treatment for Kaposi Sarcoma (KS) in Guinea, where antiretroviral coverage is low and access to KS treatment is very limited. We aimed to evalu...

    Authors: Cavin E. Bekolo, Mohamed M. Soumah, Ousseni W. Tiemtore, Abdourahimi Diallo, Joseph-Desire Yuma, Letizia Di Stefano, Carol Metcalf and Mohamed Cisse

    Citation: BMC Cancer 2017 17:806

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  10. Content type: Research article

    Cancer cachexia in elderly patients may substantially impact physical function and medical dependency. The aim of this study was to estimate the impact of cachexia on activity of daily living (ADL), length of ...

    Authors: Tateaki Naito, Taro Okayama, Takashi Aoyama, Takuya Ohashi, Yoshiyuki Masuda, Madoka Kimura, Hitomi Shiozaki, Haruyasu Murakami, Hirotsugu Kenmotsu, Tetsuhiko Taira, Akira Ono, Kazushige Wakuda, Hisao Imai, Takuya Oyakawa, Takeshi Ishii, Shota Omori…

    Citation: BMC Cancer 2017 17:800

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  11. Content type: Research article

    Utilisation of radiation therapy for regional Australia and around the world has been the focus of much health policy the last decade. Radiation therapy centres have been built in Australian regional and rural...

    Authors: Sandra C. Thompson, Shelley Cheetham and Siddhartha Baxi

    Citation: BMC Cancer 2017 17:794

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  12. Content type: Research article

    To evaluate the incidence of neck muscle spasm in nasopharyngeal carcinoma (NPC) patients that received intensity-modulated radiotherapy (IMRT), and to analyse the patient- and treatment-related risk factors a...

    Authors: Lu-Lu Zhang, Guan-Qun Zhou, Zhen-Yu Qi, Xiao-Jun He, Jia-Xiang Li, Ling-Long Tang, Yan-Ping Mao, Ai-Hua Lin, Jun Ma and Ying Sun

    Citation: BMC Cancer 2017 17:788

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  13. Content type: Research article

    The magnitude and rapidity of the tumor response to androgen deprivation is known to predict the durability of the therapy. We have investigated the predictive value of categorizing patients by the half-life o...

    Authors: Yong Jin Kang, Won Sik Jang, Jong Kyou Kwon, Cheol Yong Yoon, Joo Yong Lee, Won Sik Ham and Young Deuk Choi

    Citation: BMC Cancer 2017 17:789

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  14. Content type: Debate

    Cancer treatment during pregnancy is a growing problem especially now that women delay childbearing. Systemic treatment of these malignancies during pregnancy centers mainly on the anticancer drugs anthracycli...

    Authors: Marialuisa Framarino-dei-Malatesta, Paolo Sammartino and Angela Napoli

    Citation: BMC Cancer 2017 17:777

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  15. Content type: Case report

    Pediatric papillary thyroid carcinoma frequently presents with lymph node involvement and distant metastases. Sorafenib, an oral multikinase inhibitor, has been used to treat radioactive iodine (RAI) therapy-r...

    Authors: Yousuke Higuchi, Takayuki Motoki, Hisashi Ishida, Kiichiro Kanamitsu, Kana Washio, Takanori Oyama, Takuo Noda, Yasuko Tsurumaru, Ayumi Okada, Hirokazu Tsukahara and Akira Shimada

    Citation: BMC Cancer 2017 17:775

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  16. Content type: Research article

    To evaluate the role of ablative radiotherapy doses in the treatment of hilar or intrahepatic cholangiocarcinoma (CCC) using stereotactic body radiotherapy (SBRT).

    Authors: Eleni Gkika, Lukas Hallauer, Simon Kirste, Sonja Adebahr, Nico Bartl, Hannes Philipp Neeff, Ralph Fritsch, Volker Brass, Ursula Nestle, Anca Ligia Grosu and Thomas Baptist Brunner

    Citation: BMC Cancer 2017 17:781

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  17. Content type: Case report

    Pseudoprogression refers to a specific pattern of response sometimes observed in malignant melanoma patients receiving treatment with immune-checkpoint inhibitors. Although cases with pseudoprogression documen...

    Authors: Yukinori Ozaki, Junichi Shindoh, Yuji Miura, Hiromichi Nakajima, Ryosuke Oki, Miyuki Uchiyama, Jun Masuda, Keiichi Kinowaki, Chihiro Kondoh, Yuko Tanabe, Tsuyoshi Tanaka, Shusuke Haruta, Masaki Ueno, Shigehisa Kitano, Takeshi Fujii, Harushi Udagawa…

    Citation: BMC Cancer 2017 17:778

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  18. Content type: Case report

    Pemetrexed, a multitargeted antifolate cytotoxic agent, is currently used primarily in combination with cisplatin for metastatic non-small cell lung cancer and for malignant mesothelioma. Acute renal toxicity ...

    Authors: Maureen Assayag, Philippe Rouvier, Marion Gauthier, Ghania Costel, Philippe Cluzel, Lucile Mercadal, Gilbert Deray and Corinne Isnard Bagnis

    Citation: BMC Cancer 2017 17:770

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  19. Content type: Correspondence

    The routine use of adjuvant whole brain radiotherapy (AWBRT) after surgery or stereotactic radiosurgery is now discouraged by a number of international expert panels. Three decades of randomised studies have s...

    Authors: Mark B. Pinkham, Arjun Sahgal, Andrew P. Pullar and Matthew C. Foote

    Citation: BMC Cancer 2017 17:768

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