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Medical and radiation oncology

Section edited by Dirk Vordermark

This section focuses on clinical research that impacts on the treatment of cancer using systemic chemotherapy, targeted therapy, and radiation.

Page 12 of 16

  1. Cytoplasmic linker-associated protein 2 (CLASP2) belongs to a family of microtubule plus-end tracking proteins that localizes to the distal ends of microtubules and regulate microtubule dynamics. We speculated...

    Authors: Bisong Zhu, Lin Qi, Sulai Liu, Wentao Liu, Zhenyu Ou, Minfeng Chen, Longfei Liu, Xiongbing Zu, Jun Wang and Yuan Li

    Citation: BMC Cancer 2017 17:105

    Content type: Research article

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  2. The roles of carcinoembryonic antigen (CEA), cytokeratin 19 fragments (CYFRA21-1) and neuron-specific enolase (NSE) in metastases occurrence and poor diagnosis in specific histological classifications of lung ...

    Authors: Li Zhang, Dan Liu, Lei Li, Dan Pu, Ping Zhou, Yuting Jing, He Yu, Yanwen Wang, Yihan Zhu, Yanqi He, Yalun Li, Shuang Zhao, Zhixin Qiu and Weimin Li

    Citation: BMC Cancer 2017 17:96

    Content type: Research article

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  3. The purpose of this study was to develop an effective nomogram capable of estimating the individual survival outcomes of patients with hepatocellular carcinoma (HCC), and compare the predictive accuracy and di...

    Authors: Gang Wan, Fangyuan Gao, Jialiang Chen, Yuxin Li, Mingfan Geng, Le Sun, Yao Liu, Huimin Liu, Xue Yang, Rui Wang, Ying Feng and Xianbo Wang

    Citation: BMC Cancer 2017 17:91

    Content type: Research article

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  4. The effect of adjuvant radiotherapy on the survival outcomes of patients with mucinous rectal cancer remains unclear. This study evaluated the 5-year cause specific survival (CSS) of patients with mucinous rec...

    Authors: Qingguo Li, Yaqi Li, Weixing Dai, Sheng Wang, Ye Xu, Xinxiang Li and Sanjun Cai

    Citation: BMC Cancer 2017 17:80

    Content type: Research article

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  5. This study aimed to determine whether synchrotron radiation (SR)-based X-ray in-line phase-contrast imaging (IL-PCI) can be used to investigate the morphological characteristics of tumor neovascularization in ...

    Authors: Beilei Li, Yiqiu Zhang, Weizhong Wu, Guohao Du, Liang Cai, Hongcheng Shi and Shaoliang Chen

    Citation: BMC Cancer 2017 17:73

    Content type: Research article

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  6. Breast carcinomas with neuroendocrine features (NEBC) are a very rare entity of mammary neoplasms, WHO classification of which has recently been revised. There are very limited data available about the clinica...

    Authors: Nelli Roininen, Sari Takala, Kirsi-Maria Haapasaari, Arja Jukkola-Vuorinen, Johanna Mattson, Päivi Heikkilä and Peeter Karihtala

    Citation: BMC Cancer 2017 17:72

    Content type: Research article

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  7. CC-chemokine receptor seven (CCR7), a G-protein coupled receptor normally facilitating immune cells lymphatic homing, has recently been identified on several cancer cells in promoting invasion and lymphatic sp...

    Authors: Yu Xia, Li Liu, Ying Xiong, Qi Bai, Jiajun Wang, Wei Xi, Yang Qu, Jiejie Xu and Jianming Guo

    Citation: BMC Cancer 2017 17:70

    Content type: Research article

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  8. Mechanisms influencing breast cancer (BC) development and recurrence include hyperglycemia, hyperinsulinemia, high insulin-like growth factor-1, high circulating estrogen, inflammation and impaired cellular di...

    Authors: Livia S.A. Augustin, Massimo Libra, Anna Crispo, Maria Grimaldi, Michele De Laurentiis, Massimo Rinaldo, Massimiliano D’Aiuto, Francesca Catalano, Giuseppe Banna, Francesco Ferrau’, Rosalba Rossello, Diego Serraino, Ettore Bidoli, Samuele Massarut, Guglielmo Thomas, Davide Gatti…

    Citation: BMC Cancer 2017 17:69

    Content type: Study protocol

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  9. Chemoradiotherapy (CRT) and bio-radiotherapy (BRT) are recognized as standard therapies for head and neck cancer (HNC). Aspiration pneumonia after CRT or BRT is a common late adverse event. Our aim in this stu...

    Authors: Sadayuki Kawai, Tomoya Yokota, Yusuke Onozawa, Satoshi Hamauchi, Akira Fukutomi, Hirofumi Ogawa, Tsuyoshi Onoe, Tetsuro Onitsuka, Takashi Yurikusa, Akiko Todaka, Takahiro Tsushima, Yukio Yoshida, Yosuke Kito, Keita Mori and Hirofumi Yasui

    Citation: BMC Cancer 2017 17:59

    Content type: Research article

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  10. Cancer related thrombosis not only increases morbidity and mortality but also poses a significant financial burden on health care system. Risk of venous thromboembolism (VTE) in these patients substantially in...

    Authors: Muhammad Nauman Zahir, Quratulain Shaikh, Munira Shabbir-Moosajee and Adnan Abdul Jabbar

    Citation: BMC Cancer 2017 17:57

    Content type: Research article

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  11. Dysphagia is a significant side-effect following treatment for head and neck cancers, yet poor adherence to swallowing exercises is frequently reported in intervention studies. Behaviour change techniques (BCT...

    Authors: Roganie Govender, Christina H. Smith, Stuart A. Taylor, Helen Barratt and Benjamin Gardner

    Citation: BMC Cancer 2017 17:43

    Content type: Research article

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  12. Brain metastasis (BM) is a poor prognostic factor for non-small-cell lung cancer (NSCLC). The efficacy and roles of combining temozolomide (TMZ) with whole brain radiotherapy (WBRT) in protection neurocognitiv...

    Authors: Xia Deng, Zhen Zheng, Baochai Lin, Huafang Su, Hanbin Chen, Shaoran Fei, Zhenghua Fei, Lihao Zhao, Xiance Jin and Cong-Ying Xie

    Citation: BMC Cancer 2017 17:42

    Content type: Research article

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  13. Chemotherapy-induced peripheral neuropathy (CIPN) seriously affects the quality of life of patients with multiple myeloma (MM) as well as the response rate to chemotherapy. Acupuncture has a potential role in ...

    Authors: Xiaoyan Han, Lijuan Wang, Hongfei Shi, Gaofeng Zheng, Jingsong He, Wenjun Wu, Jimin Shi, Guoqing Wei, Weiyan Zheng, Jie Sun, He Huang and Zhen Cai

    Citation: BMC Cancer 2017 17:40

    Content type: Research article

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  14. After analysis of minor RAS mutations (KRAS exon 3, 4/NRAS) in the FIRE-3 and PRIME studies, an expanded range of RAS mutations were established as a negative predictive marker for the efficacy of anti-EGFR antib...

    Authors: Izuma Nakayama, Eiji Shinozaki, Tomohiro Matsushima, Takeru Wakatsuki, Mariko Ogura, Takashi Ichimura, Masato Ozaka, Daisuke Takahari, Mitsukuni Suenaga, Keisho Chin, Nobuyuki Mizunuma and Kensei Yamaguchi

    Citation: BMC Cancer 2017 17:38

    Content type: Research article

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  15. This matched-pair study was initiated to validate the results of a retrospective study of 186 patients published in 2007 that compared whole-brain irradiation (WBI) alone and radiosurgery (RS) alone for up to ...

    Authors: Dirk Rades, Stefan Janssen, Liesa Dziggel, Oliver Blanck, Amira Bajrovic, Theo Veninga and Steven E. Schild

    Citation: BMC Cancer 2017 17:30

    Content type: Research article

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  16. This study evaluated the distribution pattern of the Ki67-labeling index (LI) among patients at a Chinese breast cancer center, and analyzed its prognostic significance in the 2015 St Gallen consensus breast c...

    Authors: Yue Hu, Ran Gu, Jinghua Zhao, Yaping Yang, Fengtao Liu, Liang Jin, Kai Chen, Haixia Jia, Hongli Wang, Qiang Liu, Fengxi Su and Weijuan Jia

    Citation: BMC Cancer 2017 17:28

    Content type: Research article

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  17. Receptor for advanced glycation end-products (RAGE), a receptor for amyloids, is constitutively expressed in lungs and generally observed to be downregulated in lung cancer tissues. However, increasing levels ...

    Authors: Shouichi Okamoto, Shinsaku Togo, Ichiro Nagata, Kazue Shimizu, Yoshika Koinuma, Yukiko Namba, Jun Ito, Toshimasa Uekusa and Kazuhisa Takahashi

    Citation: BMC Cancer 2017 17:22

    Content type: Case report

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  18. To compare the efficacy of sorafenib and sunitinib with regard to overall survival (OS) and progression free survival (PFS) in Chinese patients with metastatic renal cell carcinoma (mRCC).

    Authors: Hai-Liang Zhang, Xi-Nan Sheng, Xue-Song Li, Hong-Kai Wang, Zhi-Hong Chi, Zhi-Song He, Ding-Wei Ye and Jun Guo

    Citation: BMC Cancer 2017 17:16

    Content type: Research article

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  19. Primary natural killer (NK)/T cell lymphoma of adrenal glands is an extremely rare tumor with aggressive clinical behavior. There have only been a few cases reported worldwide and the highest reported survival...

    Authors: Liu Hu, Weimin Xu, Mingwei Wang, Pan Wang, Guang Han and Chi Lin

    Citation: BMC Cancer 2017 17:15

    Content type: Case report

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  20. Solitary plasmacytoma (SP) is a localized neoplastic plasma cell disorder with an annual incidence of less than 450 cases. Given the rarity of this disorder, it is difficult to conduct large-scale population s...

    Authors: Nishitha Thumallapally, Ahmed Meshref, Mohammed Mousa and Terenig Terjanian

    Citation: BMC Cancer 2017 17:13

    Content type: Research article

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    The Erratum to this article has been published in BMC Cancer 2017 17:443

  21. Health-related quality-of-life (HRQOL) assessment with EORTC QLQ-C30 was prognostic for overall survival (OS) in patients with advance-stage hepatocellular carcinoma (HCC), but no data existed for early-stage ...

    Authors: Leung Li, Frankie KF Mo, Stephen L Chan, Edwin P Hui, Nelson SL Tang, Jane Koh, Linda KS Leung, Annette NY Poon, Joyce Hui, Cheuk M Chu, Kit F Lee, Brigette BY Ma, Paul BS Lai, Anthony TC Chan, Simon CH Yu and Winnie Yeo

    Citation: BMC Cancer 2017 17:8

    Content type: Research article

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  22. Discordance in hormone receptors (HR) and human epidermal growth factor receptor 2 (HER2) status between primary tumors and metastatic sites for breast cancer is well established. However, it is uncertain whic...

    Authors: Shlomit Strulov Shachar, Tanya Mashiach, Georgeta Fried, Karen Drumea, Noa Shafran, Hyman B. Muss and Gil Bar-Sela

    Citation: BMC Cancer 2017 17:7

    Content type: Research article

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  23. In head and neck cancer little is known about the kinetics of osteopontin (OPN) expression after tumor resection. In this study we evaluated the time course of OPN plasma levels before and after surgery.

    Authors: Bülent Polat, Philipp Kaiser, Gisela Wohlleben, Thomas Gehrke, Agmal Scherzad, Matthias Scheich, Uwe Malzahn, Thomas Fischer, Dirk Vordermark and Michael Flentje

    Citation: BMC Cancer 2017 17:6

    Content type: Research article

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  24. Advanced age has been shown to be a factor predicting poor survival in patients with brain metastases (BM). There have been only a few studies focusing on stereotactic radiosurgery (SRS) for elderly BM patient...

    Authors: Shoji Yomo and Motohiro Hayashi

    Citation: BMC Cancer 2016 16:948

    Content type: Research article

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  25. Primary pancreatic leiomyosarcoma is a rare pancreatic malignancy; the clinical presentation and treatment is not well-characterized. Further, the molecular mechanisms underlying its pathogenesis are not known...

    Authors: Chao Lin, Liping Wang, Jiyao Sheng, Dan Zhang, Lianyue Guan, Kai Zhao and Xuewen Zhang

    Citation: BMC Cancer 2016 16:947

    Content type: Case report

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  26. To compare efficacy and toxicity of nimotuzumab versus cisplatin (CDDP) concurrent with intensity modulated radiation therapy (IMRT) in patients with nasopharyngeal carcinoma (NPC).

    Authors: H. M. Li, P. Li, Y. J. Qian, X. Wu, L. Xie, F. Wang, H. Zhang and L. Liu

    Citation: BMC Cancer 2016 16:946

    Content type: Research article

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  27. Decisions on palliative chemotherapy (CT) for locally advanced or metastatic gastric cancer (mGC) require trade-offs between potential benefits and risks for patients. Healthcare providers and payers agree tha...

    Authors: R. Hofheinz, J. Clouth, J. Borchardt-Wagner, U. Wagner, E. Weidling, M. H. Jen and P. Brück

    Citation: BMC Cancer 2016 16:937

    Content type: Research article

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  28. Multidisciplinary team (MDT) meetings are used to optimise expert decision-making about treatment options, but such expertise is not digitally transferable between centres. To help standardise medical decision...

    Authors: Frank P. Y. Lin, Adrian Pokorny, Christina Teng, Rachel Dear and Richard J. Epstein

    Citation: BMC Cancer 2016 16:929

    Content type: Research article

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  29. There still is no evidence which neoadjuvant therapy regimen for stage II–III rectal cancer is superior. The aim of this study was to compare results achieved after long-course chemoradiotherapy (CRT) with sho...

    Authors: Tadas Latkauskas, Henrikas Pauzas, Laura Kairevice, Aleksandras Petrauskas, Zilvinas Saladzinskas, Rasa Janciauskiene, Jurate Gudaityte, Paulius Lizdenis, Saulius Svagzdys, Algimantas Tamelis and Dainius Pavalkis

    Citation: BMC Cancer 2016 16:927

    Content type: Research article

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  30. Recurrent/metastatic squamous cell carcinoma of the head and neck (SCCHN) has a poor prognosis and the combination of cisplatin and cetuximab, with or without 5-fluorouracil, is the gold standard treatment in ...

    Authors: Francesco Caponigro, Elena Di Gennaro, Franco Ionna, Francesco Longo, Corrado Aversa, Ettore Pavone, Maria Grazia Maglione, Massimiliano Di Marzo, Paolo Muto, Ernesta Cavalcanti, Antonella Petrillo, Fabio Sandomenico, Piera Maiolino, Roberta D’Aniello, Gerardo Botti, Rossella De Cecio…

    Citation: BMC Cancer 2016 16:918

    Content type: Study protocol

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  31. The treatment goal for recurrent malignant gliomas centers on disease stabilization while minimizing therapy-related side effects. Metronomic dosing of cytotoxic chemotherapy has emerged as a promising option ...

    Authors: Eric T. Wong, Joshua Timmons, Amy Callahan, Lauren O’Loughlin, Bridget Giarusso and David C. Alsop

    Citation: BMC Cancer 2016 16:914

    Content type: Research article

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  32. Standard radiotherapy is the treatment of first choice in patients with symptomatic spinal metastases, but is only moderately effective. Stereotactic body radiation therapy is increasingly used to treat spinal...

    Authors: Joanne M. van der Velden, Helena M. Verkooijen, Enrica Seravalli, Jochem Hes, A. Sophie Gerlich, Nicolien Kasperts, Wietse S. C. Eppinga, Jorrit-Jan Verlaan and Marco van Vulpen

    Citation: BMC Cancer 2016 16:909

    Content type: Study protocol

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  33. The role of radiation therapy in addition to chemotherapy has not been well established in non-oligometastatic Stage IV non-small cell lung cancer (NSCLC). We aimed to investigate overall survival (OS) of non-...

    Authors: ShengFa Su, YinXiang Hu, WeiWei Ouyang, Zhu Ma, QingSong Li, HuiQin Li, Yu Wang, XiaoHu Wang, Tao Li, JianCheng Li, Ming Chen, You Lu, YuJu Bai, ZhiXu He and Bing Lu

    Citation: BMC Cancer 2016 16:908

    Content type: Research article

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  34. PEP02 (also known as MM-398, nal-IRI) is a novel nanoparticle formulation of irinotecan encapsulated in liposomes. The aims of this study were to investigate the dose-limiting toxicity (DLT), maximum tolerated...

    Authors: Nai-Jung Chiang, Tsu-Yi Chao, Ruey-Kuen Hsieh, Cheng-Hsu Wang, Yi-Wen Wang, C. Grace Yeh and Li-Tzong Chen

    Citation: BMC Cancer 2016 16:907

    Content type: Research article

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  35. Malnutrition in gastrectomized patients receiving chemotherapy is associated with the susceptibility to chemotherapy-related adverse events. This study evaluated pre-operative nutritional status-related indice...

    Authors: Seung Hee Seo, Sung-Eun Kim, Yoon-Koo Kang, Baek-Yeol Ryoo, Min-Hee Ryu, Jae Ho Jeong, Shin Sook Kang, Mihi Yang, Jung Eun Lee and Mi-Kyung Sung

    Citation: BMC Cancer 2016 16:900

    Content type: Research article

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  36. NUT midline carcinoma (NMC) is a rare and highly aggressive malignancy. Although more information on NMC has been recently accumulating in the literature, most oncologists and pathologists remain unfamiliar wi...

    Authors: Yohei Harada, Takafumi Koyama, Kengo Takeuchi, Kazufusa Shoji, Kazuei Hoshi and Yu Oyama

    Citation: BMC Cancer 2016 16:895

    Content type: Case report

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  37. The prognosis of patients with gastrointestinal stromal tumor (GIST) after the failure of standard therapies is poor with supportive care alone. Guidelines recommend clinical trials, and patients with good per...

    Authors: Yoshiaki Nagatani, Kohei Shitara, Hideaki Bando, Yasutoshi Kuboki, Wataru Okamoto, Takashi Kojima, Takayuki Yoshino, Toshirou Nishida, Atushi Ohtsu and Toshihiko Doi

    Citation: BMC Cancer 2016 16:889

    Content type: Research article

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  38. This study aimed to identify the health-related quality of life (HRQOL) domains associated with prognosis by assessing longitudinal alterations in HRQOL in patients with advanced hepatocellular carcinoma recei...

    Authors: Masako Shomura, Tatehiro Kagawa, Haruka Okabe, Koichi Shiraishi, Shunji Hirose, Yoshitaka Arase, Kota Tsuruya, Sachiko Takahira and Tetsuya Mine

    Citation: BMC Cancer 2016 16:878

    Content type: Research article

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  39. Mammalian target of rapamycin (mTOR) is a serine/threonine protein kinase responsible for regulating ribosomal biogenesis and protein synthesis. Dysregulation of mTOR contributes to tumorigenesis, angiogenesis...

    Authors: Shuangjiang Li, Zhiqiang Wang, Jian Huang, Shan Cheng, Heng Du, Guowei Che and Yong Peng

    Citation: BMC Cancer 2016 16:877

    Content type: Research article

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  40. Relapse of acute lymphoblastic leukemia (ALL) occurring in the breast after allografting is extremely rare, with only 22 reported cases in the literature thus far. Further, the lack of a systemic analysis prov...

    Authors: Bailong Liu, Bin Liu, Xu Wang, Liang Guo, Xiaoliang Liu, Wei Han, Lihua Dong and Min Liu

    Citation: BMC Cancer 2016 16:875

    Content type: Case report

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  41. Multimodality treatment improves the chance of survival but increases the risk for long-term side effects in young cancer survivors, so-called” Adolescents and Young Adults“(AYAs). Compared to the general popu...

    Authors: J. Quidde, J. von Grundherr, B. Koch, C. Bokemeyer, G. Escherich, L. Valentini, D. Buchholz, G. Schilling and A. Stein

    Citation: BMC Cancer 2016 16:872

    Content type: Research article

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  42. Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI) readministration to lung cancer patients is common owing to the few options available. Impact of clinical factors on prognosis of EGFR-mu...

    Authors: Yu-Mu Chen, Chien-Hao Lai, Kun-Ming Rau, Cheng-Hua Huang, Huang-Chih Chang, Tung-Ying Chao, Chia-Cheng Tseng, Wen-Feng Fang, Yu-Hsiu Chung, Yi-Hsi Wang, Mao-Chang Su, Kuo-Tung Huang, Shih-Feng Liu, Hung-Chen Chen, Ya-Chun Chang, Yu-Ping Chang…

    Citation: BMC Cancer 2016 16:868

    Content type: Research article

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  43. Radiation-induced parotid damage is one of the most common complications in patients with nasopharyngeal carcinoma (NPC) undergoing radiotherapy (RT). Intravoxel incoherent motion (IVIM) magnetic resonance (MR...

    Authors: Nan Zhou, Chen Chu, Xin Dou, Ming Li, Song Liu, Lijing Zhu, Baorui Liu, Tingting Guo, Weibo Chen, Jian He, Jing Yan, Zhengyang Zhou, Xiaofeng Yang and Tian Liu

    Citation: BMC Cancer 2016 16:865

    Content type: Research article

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  44. The majority of non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutation eventually develop resistance to EGFR tyrosine kinase inhibitors (TKIs). Minimal information exist...

    Authors: Ryo Ko, Hirotsugu Kenmotsu, Masakuni Serizawa, Yasuhiro Koh, Kazushige Wakuda, Akira Ono, Tetsuhiko Taira, Tateaki Naito, Haruyasu Murakami, Mitsuhiro Isaka, Masahiro Endo, Takashi Nakajima, Yasuhisa Ohde, Nobuyuki Yamamoto, Kazuhisa Takahashi and Toshiaki Takahashi

    Citation: BMC Cancer 2016 16:864

    Content type: Research article

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  45. In a large number of patients with multiple gastrointestinal adenomatous polyps, no causal germline mutation can be found. Non-genetic factors may contribute to the development of adenomatous polyps in these u...

    Authors: Lisanne Sara Rigter, Frank G. J. Kallenberg, Barbara Bastiaansen, Theo A. M. van Os, Floor E. van Leeuwen, Monique Esther van Leerdam and Evelien Dekker

    Citation: BMC Cancer 2016 16:862

    Content type: Case report

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  46. Boron neutron capture therapy (BNCT) is a cellular-level particle radiation therapy that combines the selective delivery of boron compounds to tumour tissue with neutron irradiation. L-p-Boronophenylalanine (L-BP...

    Authors: Tsubasa Watanabe, Yoshihide Hattori, Youichiro Ohta, Miki Ishimura, Yosuke Nakagawa, Yu Sanada, Hiroki Tanaka, Satoshi Fukutani, Shin-ichiro Masunaga, Masahiro Hiraoka, Koji Ono, Minoru Suzuki and Mitsunori Kirihata

    Citation: BMC Cancer 2016 16:859

    Content type: Research article

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  47. There are clinical situations (CS) in which the use of somatostatin analogs (SSAs) in patients with neuroendocrine tumors (NET) is controversial due to lack of evidence. A Delphi study was conducted to develop...

    Authors: Isabel Sevilla, Ángel Segura, Jaume Capdevila, Carlos López, Rocío García-Carbonero and Enrique Grande

    Citation: BMC Cancer 2016 16:858

    Content type: Research article

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  48. Approximately 20 % of hepatocellular carcinoma (HCC) patients diagnosed in the early stages may benefit from potentially curative ablative therapies such as surgical resection, transplantation or radiofrequenc...

    Authors: Mihir Gandhi, Su Pin Choo, Choon Hua Thng, Say Beng Tan, Albert Su Chong Low, Peng Chung Cheow, Anthony Soon Whatt Goh, Kiang Hiong Tay, Richard Hoau Gong Lo, Brian Kim Poh Goh, Jen San Wong, David Chee Eng Ng, Khee Chee Soo, Wei Ming Liew and Pierce K. H. Chow

    Citation: BMC Cancer 2016 16:856

    Content type: Study protocol

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  49. Human Epidermal Growth Factor (Her-2/neu) has strong therapeutic implications in certain cancers like breast and gastric cancer. Literature on its frequency in colorectal cancer is scarce. In this study, we have ...

    Authors: Asma Shabbir, Talat Mirza, Abdullah Bin Khalid, Muhammad Asif Qureshi and Sadaf Ahmed Asim

    Citation: BMC Cancer 2016 16:855

    Content type: Research article

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  50. Gliomas are the most common primary brain tumors in adults and invariably carry a poor prognosis. Recent clinical studies have demonstrated the safety and compelling survival benefit when tumor treating fields...

    Authors: Jennifer Connelly, Adília Hormigo, Nimish Mohilie, Jethro Hu, Aafia Chaudhry and Nicholas Blondin

    Citation: BMC Cancer 2016 16:842

    Content type: Case report

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