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Medical and radiation oncology

Section edited by Dirk Vordermark

This section focuses on clinical research that impacts on the treatment of cancer using systemic chemotherapy, targeted therapy, and radiation.

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  1. Content type: Case report

    Adenocarcinomas of the oral cavity are rare neoplasms, and only four cases of primary colonic adenocarcinoma of the tongue have ever been described in literature. Very few information about chemotherapy sensit...

    Authors: Clizia Zichi, Marco Tampellini, Marcello Tucci, Cristina Sonetto, Chiara Baratelli, Maria P. Brizzi and Giorgio V. Scagliotti

    Citation: BMC Cancer 2018 18:470

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  2. Content type: Case report

    Radiogenic angiosarcoma of the breast (RASB) is a rare late sequela of local irradiation of the breast or chest wall after breast cancer. The prognosis of women with RASB is poor and there is no standardized t...

    Authors: Askin Dogan, Peter Kern, Beate Schultheis, Günther Häusler, Günther A. Rezniczek and Clemens B. Tempfer

    Citation: BMC Cancer 2018 18:463

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  3. Content type: Research article

    5-Fluorouracil (5FU), Folinic acid (FA), and Oxaliplatin (FOLFOX) or 5FU, FA, and Irinotecan (FOLFIRI) are standard regimens for palliative chemotherapy of metastatic colon cancer. Since data showing the influ...

    Authors: Stefan Munker, Michael Gerken, Petra Fest, Claudia Ott, Elisabeth Schnoy, Stefan Fichtner-Feigl, Philipp Wiggermann, Martin Vogelhuber, Wolfgang Herr, Christian Stroszczynski, Hans Jürgen Schlitt, Matthias Evert, Michael Reng, Monika Klinkhammer-Schalke and Andreas Teufel

    Citation: BMC Cancer 2018 18:455

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  4. Content type: Research article

    The objective of study was to determine the effect of anthracycline dose reduction and chemotherapy delays on 5-year overall survival in patients with stage I-III breast cancer, to establish the impact of mole...

    Authors: Sigita Liutkauskiene, Saulius Grizas, Kristina Jureniene, Jorune Suipyte, Akvile Statnickaite and Elona Juozaityte

    Citation: BMC Cancer 2018 18:453

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  5. Content type: Research article

    Some patients develop recurrence after curative resection and adjuvant chemotherapy. S-1, an oral fluoropyrimidine, is one of the standard regimens in adjuvant chemotherapy, and is also used in first-line trea...

    Authors: Seiji Ito, Yasuo Ohashi and Mitsuru Sasako

    Citation: BMC Cancer 2018 18:449

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  6. Content type: Research article

    To evaluate the efficacy and safety of stereotactic body radiation therapy (SBRT) in patients with small hepatocellular carcinoma(sHCC) who were ineligible for surgery or ablation therapies.

    Authors: Tao Zhang, Jing Sun, Weiping He, Huan Li, Junjie Piao, Huijun Xu and Xuezhang Duan

    Citation: BMC Cancer 2018 18:451

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  7. Content type: Research article

    To identify the incidence, recurrence pattern and prognosis of brain metastases (BM) among women with metastatic triple negative breast cancer (mTNBC) treated consecutively at a single institution during a 7-y...

    Authors: Jia Jin, Yu Gao, Jian Zhang, Leiping Wang, Biyun Wang, Jun Cao, Zhimin Shao and Zhonghua Wang

    Citation: BMC Cancer 2018 18:446

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  8. Content type: Research article

    Volumetric-modulated arc therapy (VMAT) is a highly sophisticated linear accelerator-based treatment method, and allows dose rate-changing intensity modulation with gantry rotation. We report our clinical expe...

    Authors: Yuri Jeong, Jinhong Jung, Byungchul Cho, Jungwon Kwak, Chiyoung Jeong, Jong Hoon Kim, Jin-hong Park, So Yeon Kim, Ju Hyun Shim, Kang Mo Kim, Young-Suk Lim, Han Chu Lee and Sang Min Yoon

    Citation: BMC Cancer 2018 18:416

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  9. Content type: Case report

    SMARCB1 (INI1) is a tumor-suppressor gene located at 22q11.2. Loss of SMARCB1 protein expression has been reported to be associated with atypical teratoid/rhabdoid tumors and malignant rhabdoid tumors of the kidn...

    Authors: Kazushi Yoshida, Yutaka Fujiwara, Yasushi Goto, Takashi Kohno, Akihiko Yoshida, Koji Tsuta and Yuichiro Ohe

    Citation: BMC Cancer 2018 18:398

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  10. Content type: Case report

    Treatment of recurrent nasopharyngeal carcinoma is a challenging clinical problem. We report the case of a 46 year old male showing excellent response and signs of immunostimulation following re-re-irradiation...

    Authors: T. Finazzi, T. Rordorf, K. Ikenberg, G. F. Huber, M. Guckenberger and H. I. Garcia Schueler

    Citation: BMC Cancer 2018 18:395

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  11. Content type: Research article

    Sorafenib and transarterial chemoembolization (TACE) might both provide survival benefit for advanced hepatocellular carcinoma (HCC). Adopting either as a first-line therapy carries major cost and resource imp...

    Authors: Shuling Chen, Zhenwei Peng, Mengchao Wei, Weifeng Liu, Zihao Dai, Haibo Wang, Jie Mei, Mingfong Cheong, Hanmei Zhang and Ming Kuang

    Citation: BMC Cancer 2018 18:392

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  12. Content type: Research article

    Recent studies have reported a relationship between prognosis and neutrophil-to-lymphocyte ratio (NLR) in patients with head and neck cancer (HNC). As the results are still controversial, we conducted a meta-a...

    Authors: Yalian Yu, Hongbo Wang, Aihui Yan, Hailong Wang, Xinyao Li, Jiangtao Liu and Wei Li

    Citation: BMC Cancer 2018 18:383

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  13. Content type: Research article

    Knowledge about disease and treatment is necessary before patients can consent to treatment. One of the few established instruments for evaluating whether sufficient information has been provided, is the EORTC...

    Authors: Ola Berger, Bjørn Henning Grønberg, Jon Håvard Loge, Stein Kaasa and Kari Sand

    Citation: BMC Cancer 2018 18:381

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  14. Content type: Research article

    A randomized trial demonstrated that capecitabine is at least as effective as fluorouracil in the adjuvant treatment of patients with locally advanced rectal cancer. However, not all patients receive all plann...

    Authors: Flavius Sandra-Petrescu, Florian Herrle, Iris Burkholder, Peter Kienle and Ralf-Dieter Hofheinz

    Citation: BMC Cancer 2018 18:369

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  15. Content type: Research article

    Treatment of localized gastric cancer (LGC) consists of surgical resection followed by adjuvant treatment. Both chemoradiation (CRT) and chemotherapy (CT) regimens have shown benefit in survival outcomes versu...

    Authors: Daniel M. Girardi, Mariana A. de Lima, Gabriel C. B. Pereira, Marcelo V. Negrão, Rossana V. M. López, Fernanda C. Capareli, Jorge Sabbaga and Paulo Marcelo G. Hoff

    Citation: BMC Cancer 2018 18:378

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  16. Content type: Study protocol

    Treatment of chronic myeloid leukemia with a tyrosine kinase inhibitor (TKI) offers significant improvements over previous treatments in terms of survival and toxicity yet nevertheless is associated with reduc...

    Authors: Ehab Atallah, Charles A. Schiffer, Kevin P. Weinfurt, Mei-Jie Zhang, Jerald P. Radich, Vivian G. Oehler, Javier Pinilla-Ibarz, Michael W. N. Deininger, Li Lin, Richard A. Larson, Michael J. Mauro, Joseph O. Moore, Ellen K. Ritchie, Neil P. Shah, Richard T. Silver, Martha Wadleigh…

    Citation: BMC Cancer 2018 18:359

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  17. Content type: Debate

    Fasting in disease prevention and treatment has recently become a popular topic, particularly in the context of oncology. Unfortunately, the growing attention paid by the media has created a background of spec...

    Authors: Riccardo Caccialanza, Emanuele Cereda, Francesco De Lorenzo, Gabriella Farina and Paolo Pedrazzoli

    Citation: BMC Cancer 2018 18:337

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  18. Content type: Research article

    Concurrent chemoradiotherapy followed by adjuvant chemotherapy (CCRT-AC) is currently recommended as the standard treatment for locally advanced nasopharyngeal carcinoma (LA-NPC). Neoadjuvant chemotherapy foll...

    Authors: Jiraporn Setakornnukul and Kullathorn Thephamongkhol

    Citation: BMC Cancer 2018 18:329

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  19. Content type: Research article

    Little is known about the prognostic difference of anti-EGFR therapy, cetuximab (CTX) or nimotuzumab (NTZ), concurrently with induction chemotherapy (IC, investigational arm) or RT (control arm) for patients w...

    Authors: Hao Peng, Ling-Long Tang, Xu Liu, Lei Chen, Wen-Fei Li, Yan-Ping Mao, Yuan Zhang, Li-Zhi Liu, Li Tian, Ying Guo, Ying Sun and Jun Ma

    Citation: BMC Cancer 2018 18:323

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