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Genetics, genomics and epigenetics

This section considers articles on all aspects of genome-scale analysis, functional genomics, genetic association studies, pharmacogenomics and epigenetics in relation to cancer biology, diagnosis and therapy.

Page 14 of 19

  1. A germline, variant in the BRCA1 3’UTR (rs8176318) was previously shown to predict breast and ovarian cancer risk in women from high-risk families, as well as increased risk of triple negative breast cancer. Here...

    Authors: Jemima J Dorairaj, David W Salzman, Deirdre Wall, Tiffany Rounds, Carina Preskill, Catherine AW Sullivan, Robert Lindner, Catherine Curran, Kim Lezon-Geyda, Terri McVeigh, Lyndsay Harris, John Newell, Michael J Kerin, Marie Wood, Nicola Miller and Joanne B Weidhaas

    Citation: BMC Cancer 2014 14:421

    Content type: Research article

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  2. NQO1 (NAD(P)H: quinone oxidoreductase-1), located on chromosome 16q22, functions primarily to protect normal cells from oxidant stress and electrophilic attack. Recent studies have revealed that NQO1 is expres...

    Authors: Yue Ma, Jienan Kong, Guanghai Yan, Xiangshan Ren, Dan Jin, Tiefeng Jin, Lijuan Lin and Zhenhua Lin

    Citation: BMC Cancer 2014 14:414

    Content type: Research article

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  3. To date only a handful of drugs are available for the treatment of melanoma. Among them vemurafenib, a BrafV600E specific inhibitor, showed promising results in terms of response rate and increase in median survi...

    Authors: Madhuri Bhandaru, Gholamreza Safaee Ardekani, Guohong Zhang, Magdalena Martinka, Kevin J McElwee, Gang Li and Anand Rotte

    Citation: BMC Cancer 2014 14:398

    Content type: Research article

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  4. The progression of low-risk del(5q) myelodysplastic syndrome to acute myeloid leukemia is increased when associated with mutations of TP53, or with additional chromosomal abnormalities. However, to date the progn...

    Authors: Alberto L’Abbate, Crocifissa Lo Cunsolo, Ettore Macrì, Paolo Iuzzolino, Cristina Mecucci, Claudio Doglioni, Michelina Coco, Lucia Anna Muscarella, Simona Salati, Enrico Tagliafico, Carla Minoia, Giacoma De Tullio, Attilio Guarini, Nicoletta Testoni, Claudio Agostinelli and Clelia Tiziana Storlazzi

    Citation: BMC Cancer 2014 14:396

    Content type: Case report

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  5. The hypermethylation of Alcohol dehydrogenase iron containing 1 (ADHFE1) was recently reported to be associated with colorectal cancer (CRC) differentiation. However, the effect of alcohol on ADHFE1 hypermethylat...

    Authors: Ji Wook Moon, Soo Kyung Lee, Yong Woo Lee, Jung Ok Lee, Nami Kim, Hye Jeong Lee, Jung Seon Seo, Jin Kim, Hyeon Soo Kim and Sun-Hwa Park

    Citation: BMC Cancer 2014 14:377

    Content type: Research article

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  6. There is a body of evidence that shows a link between tumorigenesis and ribosome biogenesis. The precursor of mature 18S, 28S and 5.8S ribosomal RNAs is transcribed from the ribosomal DNA gene (rDNA), which ex...

    Authors: Maria Giulia Bacalini, Annalisa Pacilli, Cristina Giuliani, Marianna Penzo, Davide Treré, Chiara Pirazzini, Stefano Salvioli, Claudio Franceschi, Lorenzo Montanaro and Paolo Garagnani

    Citation: BMC Cancer 2014 14:361

    Content type: Research article

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  7. IL-6 triggers oncogenic/angiogenic signals and the cytokine-dependent pro-cachexia cascade. The prognostic role of the functional IL-6 (promoter) rs1800795 and the IL-6R (receptor) rs8192284 single nucleotide pol...

    Authors: Annamaria Ruzzo, Vincenzo Catalano, Emanuele Canestrari, Elisa Giacomini, Daniele Santini, Giuseppe Tonini, Bruno Vincenzi, Giammaria Fiorentini, Mauro Magnani and Francesco Graziano

    Citation: BMC Cancer 2014 14:357

    Content type: Research article

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  8. The association between alpha-1 antitrypsin (AAT) deficiency and colorectal cancer (CRC) is currently controversial. The present study compares AAT serum concentrations and gene frequencies between a group of ...

    Authors: Sergio Pérez-Holanda, Ignacio Blanco, Manuel Menéndez and Luis Rodrigo

    Citation: BMC Cancer 2014 14:355

    Content type: Research article

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  9. Metastasis to the cervical (neck) lymph nodes is one of the most significant clinical factors responsible for death from oral squamous cell carcinoma (SCC). Therefore, the lymph nodes are frequently removed wh...

    Authors: Kenichiro Uchida, Ratna Veeramachaneni, Bing Huey, Aditi Bhattacharya, Brian L Schmidt and Donna G Albertson

    Citation: BMC Cancer 2014 14:353

    Content type: Research article

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  10. Esophageal cancer ranks eighth among frequent cancers worldwide. Our aim was to investigate whether and at which neoplastic stage promoter hypermethylation of CAV1 is involved in human esophageal carcinogenesis.

    Authors: Zhe Jin, Liang Wang, Ziyi Cao, Yulan Cheng, Yan Gao, Xianling Feng, Si Chen, Huimin Yu, Wenjing Wu, Zhenfu Zhao, Ming Dong, Xiaojing Zhang, Jie Liu, Xinmin Fan, Yuriko Mori and Stephen J Meltzer

    Citation: BMC Cancer 2014 14:345

    Content type: Research article

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  11. BRCA1 plays an essential role in maintaining genome stability. Inherited BRCA1 germline mutation (BRCA1+) is a determined genetic predisposition leading to high risk of breast cancer. While BRCA1+ induces breast ...

    Authors: Fengxia Xiao, Yeong C Kim, Carrie Snyder, Hongxiu Wen, Pei Xian Chen, Jiangtao Luo, Dina Becirovic, Bradley Downs, Kenneth H Cowan, Henry Lynch and San Ming Wang

    Citation: BMC Cancer 2014 14:342

    Content type: Research article

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  12. It is known that all tumors studied in sufficient number to draw conclusions show characteristic/specific chromosomal rearrangements, and the identification of these chromosomes and the genes rearranged behind...

    Authors: Francesca Micci, Lisbeth Haugom, Vera M Abeler, Ben Davidson, Claes G Tropé and Sverre Heim

    Citation: BMC Cancer 2014 14:315

    Content type: Research article

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  13. Mercaptopurine (6-MP) plays a pivotal role in treatment of childhood acute lymphoblastic leukemia (ALL); however, interindividual variability in toxicity of this drug due to genetic polymorphism in 6-MP metabo...

    Authors: Mauricio J Farfan, Carolina Salas, Cristina Canales, Felipe Silva, Milena Villarroel, Katherine Kopp, Juan P Torres, María E Santolaya and Jorge Morales

    Citation: BMC Cancer 2014 14:299

    Content type: Research article

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  14. Malignant ascites is often present at diagnostic in women with advanced ovarian cancer (OC) and its presence is associated with a worse outcome. Human peritoneal mesothelial cells (HPMCs) are key components of...

    Authors: Isabelle Matte, Denis Lane, Dimcho Bachvarov, Claudine Rancourt and Alain Piché

    Citation: BMC Cancer 2014 14:288

    Content type: Research article

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  15. The transcription factor GATA3 is a favorable prognostic indicator in estrogen receptor-α (ERα)-positive breast tumors in which it participates with ERα and FOXA1 in a complex transcriptional regulatory progra...

    Authors: Aleksandra B Adomas, Sara A Grimm, Christine Malone, Motoki Takaku, Jennifer K Sims and Paul A Wade

    Citation: BMC Cancer 2014 14:278

    Content type: Research article

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  16. Advanced squamous cervical cancer, one of the most commonly diagnosed cancers in women, still remains a major problem in oncology due to treatment failure and distant metastasis. Antitumor therapy failure is d...

    Authors: Ovidiu Balacescu, Loredana Balacescu, Oana Tudoran, Nicolae Todor, Meda Rus, Rares Buiga, Sergiu Susman, Bogdan Fetica, Laura Pop, Laura Maja, Simona Visan, Claudia Ordeanu, Ioana Berindan-Neagoe and Viorica Nagy

    Citation: BMC Cancer 2014 14:246

    Content type: Research article

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  17. Pleomorphic xanthoastrocytoma (PXA) is a rare WHO grade II tumor accounting for less than 1% of all astrocytomas. Malignant transformation into PXA with anaplastic features, is unusual and correlates with poor...

    Authors: Ramón Martínez, F Javier Carmona, Miguel Vizoso, Veit Rohde, Matthias Kirsch, Gabriele Schackert, Santiago Ropero, Werner Paulus, Alonso Barrantes, Antonio Gomez and Manel Esteller

    Citation: BMC Cancer 2014 14:213

    Content type: Research article

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  18. The epidermal growth factor receptor (EGFR) is differently expressed in breast cancer, and its presence may favor cancer progression. We hypothesized that two EGFR functional polymorphisms, a (CA)n repeat in intr...

    Authors: Marcelo Sobral Leite, Letícia Carlos Giacomin, Diogo Nascimento Piranda, Juliana Simões Festa-Vasconcellos, Vanessa Indio-do-Brasil, Sérgio Koifman, Rodrigo Soares de Moura-Neto, Marcelo Alex de Carvalho and Rosane Vianna-Jorge

    Citation: BMC Cancer 2014 14:190

    Content type: Research article

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  19. The aim of this study was to examine the association of non-random X chromosome inactivation (XCI) and loss of heterozygosity (LOH) at Xq25 with breast cancer development.

    Authors: Hui-Tzu Chen, Yao-Chung Wu, Shou-Tung Chen, Hsien-Chang Tsai and Yi-Chih Chien

    Citation: BMC Cancer 2014 14:144

    Content type: Research article

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  20. To evaluate the insulin receptor isoform mRNA expression status in non-small cell lung cancer (NSCLC) patients.

    Authors: Liyan Jiang, Wei Zhu, Katie Streicher, Chris Morehouse, Philip Brohawn, Xiaoxiao Ge, Zhengwei Dong, Xiaolu Yin, Guanshan Zhu, Yi Gu, Koustubh Ranade, Brandon W Higgs, Yihong Yao and Jiaqi Huang

    Citation: BMC Cancer 2014 14:131

    Content type: Research article

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  21. Acute leukemia in early age (EAL) is characterized by acquired genetic alterations such as MLL rearrangements (MLL-r). The aim of this case-controlled study was to investigate whether single nucleotide polymorphi...

    Authors: Mariana Emerenciano, Thayana Conceição Barbosa, Bruno Almeida Lopes, Caroline Barbieri Blunck, Alessandra Faro, Camilla Andrade, Claus Meyer, Rolf Marschalek and Maria S Pombo-de-Oliveira

    Citation: BMC Cancer 2014 14:127

    Content type: Research article

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  22. It remains presently unclear whether disease progression in colorectal carcinoma (CRC), from early, to invasive and metastatic forms, is associated to a gradual increase in genetic instability and to a scheme ...

    Authors: Béatrice Orsetti, Janick Selves, Caroline Bascoul-Mollevi, Laurence Lasorsa, Karine Gordien, Frédéric Bibeau, Blandine Massemin, François Paraf, Isabelle Soubeyran, Isabelle Hostein, Valérie Dapremont, Rosine Guimbaud, Christophe Cazaux, Michel Longy and Charles Theillet

    Citation: BMC Cancer 2014 14:121

    Content type: Research article

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  23. MicroRNAs(miRNAs) are small non-coding RNAs that participate in a variety of biologic processes, and dysregulation of miRNA is always associated with cancer development and progression. Aberrant expression of ...

    Authors: Guang-jun Zhang, He Zhou, Hua-xu Xiao, Yu Li and Tong Zhou

    Citation: BMC Cancer 2014 14:109

    Content type: Research article

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  24. GATA-5, a zinc-finger transcription factor and member of the GATA family proteins 1–6, is known to be involved in cellular differentiation. We recently found that tumor-specific hypermethylation of the GATA5 CpG ...

    Authors: Inga Peters, Natalia Dubrowinskaja, Michael Kogosov, Mahmoud Abbas, Jörg Hennenlotter, Christoph von Klot, Axel S Merseburger, Arnulf Stenzl, Ralph Scherer, Markus A Kuczyk and Jürgen Serth

    Citation: BMC Cancer 2014 14:101

    Content type: Research article

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  25. Preclinical and clinical studies have shown for decades that tumor cells demonstrate significantly enhanced sensitivity to “fever range” hyperthermia (increasing the intratumoral temperature to 42-45°C) than n...

    Authors: Clarissa Amaya, Vittal Kurisetty, Jessica Stiles, Alice M Nyakeriga, Arunkumar Arumugam, Rajkumar Lakshmanaswamy, Cristian E Botez, Dianne C Mitchell and Brad A Bryan

    Citation: BMC Cancer 2014 14:81

    Content type: Research article

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  26. Improved insight into the molecular characteristics of the different ovarian cancer subgroups is needed for developing a more individualized and optimized treatment regimen. The aim of this study was to a) ide...

    Authors: Bente Vilming Elgaaen, Ole Kristoffer Olstad, Kari Bente Foss Haug, Berit Brusletto, Leiv Sandvik, Anne Cathrine Staff, Kaare M Gautvik and Ben Davidson

    Citation: BMC Cancer 2014 14:80

    Content type: Research article

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  27. An early age at Breast Cancer (BC) onset may be a hallmark of inherited predisposition, but BRCA1/2 mutations are only found in a minority of younger BC patients. Among the others, a fraction may carry mutatio...

    Authors: Laura Maria Pradella, Cecilia Evangelisti, Claudia Ligorio, Claudio Ceccarelli, Iria Neri, Roberta Zuntini, Laura Benedetta Amato, Simona Ferrari, Alberto Maria Martelli, Giuseppe Gasparre and Daniela Turchetti

    Citation: BMC Cancer 2014 14:70

    Content type: Case report

    Published on:

  28. Tumor expression of estrogen receptor (ER) is an important marker of prognosis, and is predictive of response to endocrine therapy in breast cancer. Several studies have observed that epigenetic events, such m...

    Authors: Joaquina Martínez-Galán, Blanca Torres-Torres, María Isabel Núñez, Jesús López-Peñalver, Rosario Del Moral, José Mariano Ruiz De Almodóvar, Salomón Menjón, Ángel Concha, Clara Chamorro, Sandra Ríos and Juan Ramón Delgado

    Citation: BMC Cancer 2014 14:59

    Content type: Research article

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  29. Methylentetrahydrofolate reductase (MTHFR) plays a major role in folate metabolism and consequently could be an important factor for the efficacy of a treatment with 5-fluorouracil. Our aim was to evaluate the...

    Authors: Susanne Blank, Sivaramakrishna Rachakonda, Gisela Keller, Wilko Weichert, Florian Lordick, Rupert Langer, Christoph Springfeld, Thomas Bruckner, Karen Becker, Rajiv Kumar and Katja Ott

    Citation: BMC Cancer 2014 14:58

    Content type: Research article

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  30. The development of colorectal cancer (CRC) is accompanied by extensive epigenetic changes, including frequent regional hypermethylation particularly of gene promoter regions. Specific genes, including SEPT9, VIM1

    Authors: Susan M Mitchell, Jason P Ross, Horace R Drew, Thu Ho, Glenn S Brown, Neil FW Saunders, Konsta R Duesing, Michael J Buckley, Rob Dunne, Iain Beetson, Keith N Rand, Aidan McEvoy, Melissa L Thomas, Rohan T Baker, David A Wattchow, Graeme P Young…

    Citation: BMC Cancer 2014 14:54

    Content type: Research article

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  31. Breast cancer is the most common malignancy that develops in women, responsible for the highest cancer-associated death rates. Triple negative breast cancers represent an important subtype that have an aggress...

    Authors: Kelly A Avery-Kiejda, Stephen G Braye, Andrea Mathe, John F Forbes and Rodney J Scott

    Citation: BMC Cancer 2014 14:51

    Content type: Research article

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  32. Hypoxia-induced genes are potential targets in cancer therapy. Responses to hypoxia have been extensively studied in vitro, however, they may differ in vivo due to the specific tumor microenvironment. In this stu...

    Authors: Katharina Leithner, Christoph Wohlkoenig, Elvira Stacher, Jörg Lindenmann, Nicole A Hofmann, Birgit Gallé, Christian Guelly, Franz Quehenberger, Philipp Stiegler, Freyja-Maria Smolle-Jüttner, Sjaak Philipsen, Helmut H Popper, Andelko Hrzenjak, Andrea Olschewski and Horst Olschewski

    Citation: BMC Cancer 2014 14:40

    Content type: Research article

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  33. Renal cell carcinoma (RCC) is marked by high mortality rate. To date, no robust risk stratification by clinical or molecular prognosticators of cancer-specific survival (CSS) has been established for early sta...

    Authors: Daniel Vergho, Susanne Kneitz, Andreas Rosenwald, Charlotte Scherer, Martin Spahn, Maximilian Burger, Hubertus Riedmiller and Burkhard Kneitz

    Citation: BMC Cancer 2014 14:25

    Content type: Research article

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  34. Primary small cell carcinoma of the esophagus (PSCCE) is a rare and aggressive tumor with poor prognosis. The aim of this study was to investigate the existence of EGFR, KRAS, PIK3CA and PTEN mutations in PSCCE.

    Authors: Zhimin Zhang, Hualiang Xiao, Fei Xie, Hui Zhang, Chuan Chen, He Xiao, Zhenzhou Yang, Dong Wang, Zengpeng Li and Ge Wang

    Citation: BMC Cancer 2014 14:19

    Content type: Research article

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  35. The approval of vemurafenib in the US 2011 and in Europe 2012 improved the therapy of not resectable or metastatic melanoma. Patients carrying a substitution of valine to glutamic acid at codon 600 (p.V600E) o...

    Authors: Michaela Angelika Ihle, Jana Fassunke, Katharina König, Inga Grünewald, Max Schlaak, Nicole Kreuzberg, Lothar Tietze, Hans-Ulrich Schildhaus, Reinhard Büttner and Sabine Merkelbach-Bruse

    Citation: BMC Cancer 2014 14:13

    Content type: Research article

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  36. Resistance of the highly aggressive glioblastoma multiforme (GBM) to drug therapy is a major clinical problem resulting in a poor patient’s prognosis. Beside promoter methylation of the O 6 ...

    Authors: Moritz C Oberstadt, Sandra Bien-Möller, Kerstin Weitmann, Susann Herzog, Katharina Hentschel, Christian Rimmbach, Silke Vogelgesang, Ellen Balz, Matthias Fink, Heike Michael, Jan-Philip Zeden, Henrike Bruckmüller, Anneke N Werk, Ingolf Cascorbi, Wolfgang Hoffmann, Dieter Rosskopf…

    Citation: BMC Cancer 2013 13:617

    Content type: Research article

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  37. Aberrant methylation at imprinted differentially methylated regions (DMRs) in human 11p15.5 has been reported in many tumors including hepatoblastoma. However, the methylation status of imprinted DMRs in impri...

    Authors: Janette Mareska Rumbajan, Toshiyuki Maeda, Ryota Souzaki, Kazumasa Mitsui, Ken Higashimoto, Kazuhiko Nakabayashi, Hitomi Yatsuki, Kenichi Nishioka, Ryoko Harada, Shigehisa Aoki, Kenichi Kohashi, Yoshinao Oda, Kenichiro Hata, Tsutomu Saji, Tomoaki Taguchi, Tatsuro Tajiri…

    Citation: BMC Cancer 2013 13:608

    Content type: Research article

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  38. Despite an initial good response to epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI), resistance to treatment eventually develops. Although several resistance mechanisms have been discov...

    Authors: Wonjun Ji, Chang-Min Choi, Jin Kyung Rho, Se Jin Jang, Young Soo Park, Sung-Min Chun, Woo Sung Kim, Jung-Shin Lee, Sang-We Kim, Dae Ho Lee and Jae Cheol Lee

    Citation: BMC Cancer 2013 13:606

    Content type: Research article

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  39. Nonpolypoid adenomas are a subgroup of colorectal adenomas that have been associated with a more aggressive clinical behaviour compared to their polypoid counterparts. A substantial proportion of nonpolypoid a...

    Authors: Quirinus JM Voorham, Jerry Janssen, Marianne Tijssen, Suzanne Snellenberg, Sandra Mongera, Nicole CT van Grieken, Heike Grabsch, Martin Kliment, Bjorn J Rembacken, Chris JJ Mulder, Manon van Engeland, Gerrit A Meijer, Renske DM Steenbergen and Beatriz Carvalho

    Citation: BMC Cancer 2013 13:603

    Content type: Research article

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  40. Recent genomic evidence suggests frequent phosphatidylinositide 3-kinase (PI3K) pathway activation in human papillomavirus (HPV) positive oropharyngeal squamous cell carcinoma. Mutations/amplification of the g...

    Authors: Simion I Chiosea, Jennifer R Grandis, Vivian W Y Lui, Brenda Diergaarde, Jessica H Maxwell, Robert L Ferris, Seungwon W Kim, Alyssa Luvison, Megan Miller and Marina N Nikiforova

    Citation: BMC Cancer 2013 13:602

    Content type: Research article

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  41. Glutaminase 2 (Gls2) is a p53 target gene and is known to play an important role in energy metabolism. Gls2 has been reported to be downregulated in human hepatocellular carcinomas (HCC). However, the underlyi...

    Authors: Jianbin Zhang, Cheng Wang, Mingquan Chen, Jianping Cao, Ying Zhong, Liting Chen, Han-Ming Shen and Dajing Xia

    Citation: BMC Cancer 2013 13:601

    Content type: Research article

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  42. The genetic changes in gastric adenocarcinoma are extremely complex and reliable tumor markers have not yet been identified. There are also remarkable geographical differences in the distribution of this disea...

    Authors: Lars L Eftang, Ying Esbensen, Tone M Tannæs, Gustav P Blom, Ida RK Bukholm and Geir Bukholm

    Citation: BMC Cancer 2013 13:586

    Content type: Research article

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  43. DNA methylation is a well-known epigenetic mechanism involved in epigenetic gene regulation. Several genes were reported hypermethylated in CRC, althought no gene marker was proven to be individually of suffic...

    Authors: Jean-Pierre Roperch, Roberto Incitti, Solène Forbin, Floriane Bard, Hicham Mansour, Farida Mesli, Isabelle Baumgaertner, Francesco Brunetti and Iradj Sobhani

    Citation: BMC Cancer 2013 13:566

    Content type: Research article

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  44. The tumor suppressor p53 is a sequence-specific transcription factor that regulates an extensive network of coding genes, long non-coding RNAs and microRNAs, that establish intricate gene regulatory circuits i...

    Authors: Alessandra Bisio, Veronica De Sanctis, Valerio Del Vescovo, Michela A Denti, Anil G Jegga, Alberto Inga and Yari Ciribilli

    Citation: BMC Cancer 2013 13:552

    Content type: Research article

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  45. Current evidence implicates aberrant microRNA expression patterns in human malignancies; measurement of microRNA expression may have diagnostic and prognostic applications. Roles for microRNAs in head and neck...

    Authors: Patricia Severino, Holger Brüggemann, Flavia Maziero Andreghetto, Carme Camps, Maria de Fatima Garrido Klingbeil, Welbert Oliveira de Pereira, Renata Machado Soares, Raquel Moyses, Victor Wünsch-Filho, Monica Beatriz Mathor, Fabio Daumas Nunes, Jiannis Ragoussis and Eloiza Helena Tajara

    Citation: BMC Cancer 2013 13:533

    Content type: Research article

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  46. Colorectal cancer (CRC) is one of the most common and comprehensively studied malignancies. Hypoxic conditions during formation of CRC may support the development of more aggressive cancers. Hypoxia inducible ...

    Authors: Agnieszka A Rawluszko, Katarzyna E Bujnicka, Karolina Horbacka, Piotr Krokowicz and Paweł P Jagodziński

    Citation: BMC Cancer 2013 13:526

    Content type: Research article

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  47. Breast cancer is the most common type of cancer and the second leading cause of cancer-death among women in Poland. The known high-risk mutations account for 25% of familial aggregation cases and 5% of total b...

    Authors: Joanna K Ledwoń, Ewa E Hennig, Natalia Maryan, Krzysztof Goryca, Dorota Nowakowska, Anna Niwińska and Jerzy Ostrowski

    Citation: BMC Cancer 2013 13:510

    Content type: Research article

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  48. Genetic aberrations are required for the progression of HPV-induced cervical precancers. A prerequisite for clonal expansion of cancer cells is unlimited proliferative capacity. In a cell culture model for cer...

    Authors: Melanie Liesenfeld, Sandy Mosig, Harald Funke, Lars Jansen, Ingo B Runnebaum, Matthias Dürst and Claudia Backsch

    Citation: BMC Cancer 2013 13:507

    Content type: Research article

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  49. Small intestinal neuroendocrine tumors (SI-NETs) are typically slow-growing tumors that have metastasized already at the time of diagnosis. The purpose of the present study was to further refine and define reg...

    Authors: Jamileh Hashemi, Omid Fotouhi, Luqman Sulaiman, Magnus Kjellman, Anders Höög, Jan Zedenius and Catharina Larsson

    Citation: BMC Cancer 2013 13:505

    Content type: Research article

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  50. MTO1 and MRPL41 are nuclear-encoded mitochondrial genes encoding a mitochondrial tRNA-modifying enzyme and a mitochondrial ribosomal protein, respectively. Although both genes have been known to have potential...

    Authors: Tae Woo Kim, Byungtak Kim, Ju Hee Kim, Seongeun Kang, Sung-Bin Park, Gookjoo Jeong, Han-Sung Kang and Sun Jung Kim

    Citation: BMC Cancer 2013 13:502

    Content type: Research article

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