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Epidemiology, prevention and public health

This section aims to consider publications which focus on all aspects of cancer epidemiology including risk factors for disease initiation and development, social determinants, environmental, behavioural, and occupational correlates, and the impact of health policies, practices and interventions on the community.

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  1. Content type: Research article

    The goal of this exploratory study was to develop and assess a prediction model which can potentially be used as a biomarker of breast cancer, based on anthropometric data and parameters which can be gathered ...

    Authors: Miguel Patrício, José Pereira, Joana Crisóstomo, Paulo Matafome, Manuel Gomes, Raquel Seiça and Francisco Caramelo

    Citation: BMC Cancer 2018 18:29

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  2. Content type: Study protocol

    Cancer survival comes at a price: pediatric cancer survivors bear a high risk for a wide range of cognitive difficulties. Therefore, interventions targeting these difficulties are required. The aim of the pres...

    Authors: Valentin Benzing, Noëmi Eggenberger, Janine Spitzhüttl, Valerie Siegwart, Manuela Pastore-Wapp, Claus Kiefer, Nedelina Slavova, Michael Grotzer, Theda Heinks, Mirko Schmidt, Achim Conzelmann, Maja Steinlin, Regula Everts and Kurt Leibundgut

    Citation: BMC Cancer 2018 18:18

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  3. Content type: Research article

    Availability and affordability of anticancer medicines is a matter of great concern especially for low and middle income countries e.g., Pakistan. Prime focus of this study was to evaluate the availability of ...

    Authors: Muhammad Rehan Sarwar, Sadia Iftikhar and Anum Saqib

    Citation: BMC Cancer 2018 18:14

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  4. Content type: Research article

    Head and neck cancer squamous cell carcinoma (HNSSC) patients report substantial rates of clinically significant depression and/or anxiety, with dysphagia being a predictor of distress and poorer quality of li...

    Authors: J. M. Patterson, M. Fay, C. Exley, E. McColl, M. Breckons and V. Deary

    Citation: BMC Cancer 2018 18:1

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  5. Content type: Research article

    Globally, cancer is one of the leading causes of mortality. High treatment cost, partly owing to higher prices of anti-cancer drugs, presents a significant burden on patients and healthcare systems. The aim of...

    Authors: Shahrzad Salmasi, Kah Seng Lee, Long Chiau Ming, Chin Fen Neoh, Mahmoud E. Elrggal, Zaheer-Ud- Din Babar, Tahir Mehmood Khan and Muhammad Abdul Hadi

    Citation: BMC Cancer 2017 17:903

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  6. Content type: Research article

    In Denmark, national roll-out of a population-based, screening mammography program took place in 2007–2010. We report on outcome of the first four biennial invitation rounds.

    Authors: Elsebeth Lynge, Martin Bak, My von Euler-Chelpin, Niels Kroman, Anders Lernevall, Nikolaj Borg Mogensen, Walter Schwartz, Adam Jan Wronecki and Ilse Vejborg

    Citation: BMC Cancer 2017 17:897

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  7. Content type: Research article

    Use of dietary supplements among cancer survivors is common and controversial, but information on the amount of nutrients from supplements among cancer survivors is limited. We examined the amount of nutrients...

    Authors: Sihan Song, Jiyoung Youn, Yun Jung Lee, Minji Kang, Taisun Hyun, YoonJu Song and Jung Eun Lee

    Citation: BMC Cancer 2017 17:891

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  8. Content type: Research article

    Cervical cancer is the most common cancer in women living in Vientiane, Lao People’s Democratic Republic (PDR). This study examines cervical cytology using a liquid-based cytology (LBC) method and reports the ...

    Authors: Reika Takamatsu, Viengvansay Nabandith, Vatsana Pholsena, Phouthasone Mounthisone, Katsu Nakasone, Kentarou Ohtake and Naoki Yoshimi

    Citation: BMC Cancer 2017 17:872

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  9. Content type: Research article

    Case reports, retrospective analyses, and observational studies have linked the use of cisplatin to increased risk of second cancers, especially life-threatening secondary leukemia. We therefore performed a sy...

    Authors: Fei Liang, Sheng Zhang, Hongxi Xue and Qiang Chen

    Citation: BMC Cancer 2017 17:871

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  10. Content type: Research article

    Low income and uninsured individuals often have lower adherence to cancer screening for breast, cervical and colorectal cancer. Health fairs are a common community outreach strategy used to provide cancer-rela...

    Authors: Cam Escoffery, Shuting Liang, Kirsten Rodgers, Regine Haardoerfer, Grace Hennessy, Kendra Gilbertson, Natalia I. Heredia, Leticia A. Gatus and Maria E. Fernandez

    Citation: BMC Cancer 2017 17:865

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  11. Content type: Research article

    Obesity is linked to poor disease outcomes in breast cancer patients. However, this link was mostly based on body weight or BMI rather than body-fat. The purpose of this study was to evaluate the relationship ...

    Authors: Li-Ni Liu, Yung-Chang Lin, Christine Miaskowski, Shin-Cheh Chen and Mei-Ling Chen

    Citation: BMC Cancer 2017 17:863

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  12. Content type: Research article

    Physician recommendations for colorectal cancer (CRC) screening have consistently been shown to be a strong predictor of screening. The aim of this study was to investigate perceptions of CRC screening modalit...

    Authors: Hye Young Shin, Mina Suh, Boyoung Park, Jae Kwan Jun and Kui Son Choi

    Citation: BMC Cancer 2017 17:860

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  13. Content type: Research article

    In a previous paper, we had assumed that the risk of screen-detected breast cancer mostly reflects inherent risk, and the risk of whether a breast cancer is interval versus screen-detected mostly reflects risk...

    Authors: Kavitha Krishnan, Laura Baglietto, Jennifer Stone, Catriona McLean, Melissa C. Southey, Dallas R. English, Graham G. Giles and John L. Hopper

    Citation: BMC Cancer 2017 17:859

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  14. Content type: Research article

    Evidence suggests that risk of colorectal and prostate cancer is increased among those with a family history of the same disease, particularly among first-degree relatives. However, the aggregation of colorect...

    Authors: Jennifer L. Beebe-Dimmer, Cecilia Yee, Electra Paskett, Ann G. Schwartz, Dorothy Lane, Nynikka R. A. Palmer, Cathryn H. Bock, Rami Nassir and Michael S. Simon

    Citation: BMC Cancer 2017 17:848

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  15. Content type: Study protocol

    In Chile, more than 500 women die every year from cervical cancer, and a majority of Chilean women are not up-to-date with their Papanicolau (Pap) test. Mobile health has great potential in many health areas, ...

    Authors: McKenzie C. Momany, Javiera Martinez-Gutierrez, Mauricio Soto, Daniel Capurro, Francis Ciampi, Beti Thompson and Klaus Puschel

    Citation: BMC Cancer 2017 17:847

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  16. Content type: Research article

    The prevalence of Hereditary Non-Polyposis Colorectal Cancer (HNPCC) is 2 to 5% in the Caucasian population. HNPCC is caused by genomic mutations in DNA mismatch repair genes (MMR), namely MLH1, MSH2, MSH6, PMS2,

    Authors: Jasmine Lee, Yin-Yi Xiao, Yan Yu Sun, Jasminka Balderacchi, Bradley Clark, Jatin Desani, Vivek Kumar, Angela Saverimuthu, Khin Than Win, Yiwu Huang and Yiqing Xu

    Citation: BMC Cancer 2017 17:843

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  17. Content type: Research article

    Low serum selenium status has been associated with increased risk of esophageal squamous cell carcinoma (ESCC). East Africa is a region of high ESCC incidence and is known to have low soil selenium levels, but...

    Authors: Natalie R. Pritchett, Stephen L. Burgert, Gwen A. Murphy, John D. Brockman, Russell E. White, Justus Lando, Robert Chepkwony, Mark D. Topazian, Christian C. Abnet, Sanford M. Dawsey and Michael M. Mwachiro

    Citation: BMC Cancer 2017 17:835

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  18. Content type: Study protocol

    Despite guidelines for cervical cancer prevention in low-resource countries, a very small proportion of women in these settings undergo screening, and even fewer women are successfully treated. Using pilot dat...

    Authors: Megan J. Huchko, James G. Kahn, Jennifer S. Smith, Robert A. Hiatt, Craig R. Cohen and Elizabeth Bukusi

    Citation: BMC Cancer 2017 17:826

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  19. Content type: Research article

    The association of malnutrition in early life with breast cancer risk has been studied in Europe by investigating survivors of the Dutch Hunger Winter Famine, but not in China. We evaluated the effect of expos...

    Authors: Dandan He, Yuan Fang, Marc J. Gunter, Dongli Xu, Yanping Zhao, Jie Zhou, Hong Fang and Wang Hong Xu

    Citation: BMC Cancer 2017 17:824

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  20. Content type: Study protocol

    Beyond survival of nowadays >80%, modern childhood cancer treatment strives to preserve long-term health and quality of life. However, the majority of today’s survivors suffer from short- and long-term adverse...

    Authors: Corina S. Rueegg, Susi Kriemler, Simeon J. Zuercher, Christina Schindera, Andrea Renner, Helge Hebestreit, Christian Meier, Prisca Eser and Nicolas X. von der Weid

    Citation: BMC Cancer 2017 17:822

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  21. Content type: Research article

    In spite of the increasing incidence of in situ breast cancer, the information about the risk factors of in situ breast cancer (DCIS) is scarce as compared to the information available for invasive ductal brea...

    Authors: Hyeonyoung Ko, Jinyoung Shin, Jeong Eon Lee, Seok Jin Nam, Tuong Linh Nguyen, John Llewelyn Hopper and Yun-Mi Song

    Citation: BMC Cancer 2017 17:821

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  22. Content type: Research article

    Danish cancer patients have lower survival rates than patients in many other western countries. Half of the patients present with non-alarm symptoms and thus have a long diagnostic pathway. Consequently, an ur...

    Authors: Esben Næser, Henrik Møller, Ulrich Fredberg, Jan Frystyk and Peter Vedsted

    Citation: BMC Cancer 2017 17:817

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  23. Content type: Research article

    Recent advances in methodologies utilizing “big data” have allowed researchers to investigate the use of common internet search engines as a real time tool to track disease. Little is known about its utility w...

    Authors: Xiaodong Huang, Peter Baade, Danny R. Youlden, Philippa H. Youl, Wenbiao Hu and Michael G. Kimlin

    Citation: BMC Cancer 2017 17:816

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  24. Content type: Research article

    In the absence of routine ovarian cancer screening, promoting help-seeking in response to ovarian symptoms is a potential route to early diagnosis. The factors influencing women’s anticipated time to presentat...

    Authors: Stephanie Smits, Jacky Boivin, Usha Menon and Kate Brain

    Citation: BMC Cancer 2017 17:814

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  25. Content type: Research article

    Epithelial cell adhesion molecule (EpCAM) is a promising biomarker for squamous cell carcinoma (SCC) of the uterine cervix, because it is over-expressed in various cancers of epithelial origin. However, EpCAM ...

    Authors: Warangkana Chantima, Charin Thepthai, Pornsuk Cheunsuchon and Tararaj Dharakul

    Citation: BMC Cancer 2017 17:811

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  26. Content type: Research article

    In 2012 a new cancer patient pathway for patients with non-specific symptoms and signs of cancer (NSSC-CPP) was introduced in Denmark. Limited information is available about the patients referred to the NSSC-C...

    Authors: Sara Falk Jørgensen, Pernille Ravn, Søren Thorsen and Signe Westring Worm

    Citation: BMC Cancer 2017 17:809

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  27. Content type: Research article

    Autopsy studies demonstrate the prevalence pool of incidental breast cancer in the population, but estimates are uncertain due to small numbers in any primary study. We aimed to conduct a systematic review of ...

    Authors: Elizabeth T. Thomas, Chris Del Mar, Paul Glasziou, Gordon Wright, Alexandra Barratt and Katy J. L. Bell

    Citation: BMC Cancer 2017 17:808

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  28. Content type: Research article

    Breast cancer is the most common malignancy accounting for 25% of all cancers in females. In Africa, breast cancer prevalence and mortality are steadily increasing. Knowledge of hormone receptors and human epi...

    Authors: Asmerom Tesfamariam Sengal, Nada Suliman Haj-Mukhtar, Ahmed Mohammed Elhaj, Shahinaz Bedri, Eva Johanna Kantelhardt and Ahmed A. Mohamedani

    Citation: BMC Cancer 2017 17:804

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  29. Content type: Research article

    In Europe, treatment of metastatic colorectal cancer (mCRC) with panitumumab requires prior confirmation of RAS wild-type mutation status. Two studies – a physician survey and a medical records review (MRR) – wer...

    Authors: J. Han van Krieken, George Kafatos, James Bennett, Laurent Mineur, Jiří Tomášek, Etienne Rouleau, Pavel Fabian, Giovanna De Maglio, Pilar García-Alfonso, Giuseppe Aprile, Parijan Parkar, Gerald Downey, Gaston Demonty and Jörg Trojan

    Citation: BMC Cancer 2017 17:798

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  30. Content type: Research article

    Subjective cognitive impairment can be a significant and prevalent problem for gynaecological cancer survivors. The aims of this study were to assess subjective cognitive functioning in gynaecological cancer s...

    Authors: Yingchun Zeng, Andy S. K. Cheng, Ting Song, Xiujie Sheng, Yang Zhang, Xiangyu Liu and Chetwyn C. H. Chan

    Citation: BMC Cancer 2017 17:796

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  31. Content type: Research article

    There is a dramatic rise in the incidence of Human papillomavirus (HPV) – associated head and neck squamous cell carcinoma (HNSCC) in the world, with considerable variation by geography, gender and ethnicity. ...

    Authors: Mushfiq H. Shaikh, Aminul I. Khan, Anwar Sadat, Ahmed H. Chowdhury, Shahed A. Jinnah, Vinod Gopalan, Alfred K. Lam, Daniel T. W. Clarke, Nigel A. J. McMillan and Newell W. Johnson

    Citation: BMC Cancer 2017 17:792

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  32. Content type: Research article

    Where resources are available, the World Health Organization recommends cervical cancer screening with human papillomavirus (HPV) DNA testing and subsequent treatment of HPV-positive women with timely cryother...

    Authors: Nicole G. Campos, Vivien Tsu, Jose Jeronimo, Mercy Mvundura and Jane J. Kim

    Citation: BMC Cancer 2017 17:791

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  33. Content type: Study protocol

    In recent years growing interest has been posed on alternative ways to screen women for breast cancer involving different imaging techniques or adjusting screening interval by breast cancer risk estimates. A n...

    Authors: Livia Giordano, Federica Gallo, Elisabetta Petracci, Giovanna Chiorino and Nereo Segnan

    Citation: BMC Cancer 2017 17:785

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  34. Content type: Database

    The KHP PCaBB was established in 2013 and recruits donors from the Urology or Oncology Departments at Guy’s Hospital in London (UK). Prostate cancer patients may be approached to give their consent for biobank...

    Authors: S. R. Saifuddin, W. Devlies, A. Santaolalla, F. Cahill, G. George, D. Enting, S. Rudman, P. Cathcart, B. Challacombe, P. Dasgupta, C. Galustian, A. Chandra, S. Chowdhury, C. Gillett and M. Van Hemelrijck

    Citation: BMC Cancer 2017 17:784

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  35. Content type: Research article

    Among colorectal cancer (CRC) survivors, how the prior tumor location affects the risk of subsequent primary colorectal cancer (SPCRC) and the outcome of those suffering from SPCRC remain unknown.

    Authors: Jiao Yang, Xianglin L. Du, Shuting Li, Yinying Wu, Meng Lv, Danfeng Dong, Lingxiao Zhang, Zheling Chen, Biyuan Wang, Fan Wang, Yanwei Shen, Enxiao Li, Min Yi and Jin Yang

    Citation: BMC Cancer 2017 17:783

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  36. Content type: Research article

    Recommending the optimal treatment for an individual patient requires a well-balanced consideration of various medical, social and ethical factors. The interplay of these factors, interpretation of the patient...

    Authors: I. Otte, S. Salloch, A. Reinacher-Schick and J. Vollmann

    Citation: BMC Cancer 2017 17:780

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  37. Content type: Research article

    Breast cancer is the top cancer by incidence and mortality in Singaporean women. Mammography is by far its best screening tool, but current recommended age and interval may not yield the most benefit. Recent s...

    Authors: Xin Yi Wong, Kok Joon Chong, Janine A. van Til and Hwee Lin Wee

    Citation: BMC Cancer 2017 17:776

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  38. Content type: Research article

    This study evaluated the cost-effectiveness of replacing standard intravenous therapy (taxane) with oral S-1 therapy for first-line metastatic breast cancer treatment.

    Authors: Takeru Shiroiwa, Takashi Fukuda, Kojiro Shimozuma, Mitsuko Mouri, Yasuhiro Hagiwara, Takuya Kawahara, Shozo Ohsumi, Yasuo Hozumi, Yoshiaki Sagara, Yasuo Ohashi and Hirofumi Mukai

    Citation: BMC Cancer 2017 17:773

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  39. Content type: Research article

    The aim of the study was to evaluate the current rate of molecular testing prescription (KRAS codons 12/13, BRAF and microsatellite instability (MSI)) in newly diagnosed colorectal cancer (CRC) patients and to de...

    Authors: Quentin Thiebault, Gautier Defossez, Lucie Karayan-Tapon, Pierre Ingrand, Christine Silvain and David Tougeron

    Citation: BMC Cancer 2017 17:765

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  40. Content type: Research article

    Beneficial effects of aspirin and non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) against recurrent colorectal adenomas have been documented in systematic reviews; however, the results have not been ...

    Authors: Sajesh K. Veettil, Kean Ghee Lim, Siew Mooi Ching, Surasak Saokaew, Pochamana Phisalprapa and Nathorn Chaiyakunapruk

    Citation: BMC Cancer 2017 17:763

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  41. Content type: Research article

    Endometrial cancer is the fourth most common cancer in European women. The major risk factors for endometrial cancer are related to the exposure of endometrium to estrogens not opposed to progestogens, that ca...

    Authors: Fulvio Ricceri, Maria Teresa Giraudo, Francesca Fasanelli, Dario Milanese, Veronica Sciannameo, Laura Fiorini and Carlotta Sacerdote

    Citation: BMC Cancer 2017 17:757

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  42. Content type: Research article

    Women with pathogenic BRCA germline mutations have an increased risk for breast and ovarian cancer that seems to be modified by life-style factors. Though, randomized trials investigating the impact of lifestyle ...

    Authors: Marion Kiechle, Ricarda Dukatz, Maryam Yahiaoui-Doktor, Anika Berling, Maryam Basrai, Vera Staiger, Uwe Niederberger, Nicole Marter, Jacqueline Lammert, Sabine Grill, Katharina Pfeifer, Kerstin Rhiem, Rita K. Schmutzler, Matthias Laudes, Michael Siniatchkin, Martin Halle…

    Citation: BMC Cancer 2017 17:752

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  43. Content type: Research article

    Breast cancer patients are at an increased risk of venous thromboembolism (VTE). However, current evidence as to whether VTE increases the risk of mortality in breast cancer patients is conflicting. We present...

    Authors: Umair T. Khan, Alex J. Walker, Sadaf Baig, Tim R. Card, Cliona C. Kirwan and Matthew J. Grainge

    Citation: BMC Cancer 2017 17:747

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  44. Content type: Research article

    To date, research on stigmatization among cancer patients and related psychosocial consequences has been scarce and mostly based on small and highly selected samples. We investigated stigmatization and its imp...

    Authors: J. Ernst, A. Mehnert, A. Dietz, B. Hornemann and P. Esser

    Citation: BMC Cancer 2017 17:741

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  45. Content type: Research article

    Medication non-adherence is associated with poor health outcomes and increased health care costs. Depending on definitions, reported non-adherence rates in cancer patients ranges between 16 and 100%, which ill...

    Authors: Linda Bouwman, Corien M. Eeltink, Otto Visser, Jeroen J. W. M. Janssen and Jolanda M. Maaskant

    Citation: BMC Cancer 2017 17:739

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