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Epidemiology, prevention and public health

Section edited by Manami Inoue

This section aims to consider publications which focus on all aspects of cancer epidemiology including risk factors for disease initiation and development, social determinants, environmental, behavioural, and occupational correlates, and the impact of health policies, practices and interventions on the community.

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  1. Content type: Research article

    Studies on alternative routes to diagnosis stimulated successful policy interventions reducing the number of emergency diagnoses and associated mortality risk. A dearth of evidence on the costs of such interve...

    Authors: Mauro Laudicella, Brendan Walsh, Elaine Burns, Paolo Li Donni and Peter C. Smith

    Citation: BMC Cancer 2018 18:394

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  2. Content type: Research article

    To examine associations between occupational exposure to petroleum-based and oxygenated solvents and the risk of hypopharyngeal and laryngeal cancer.

    Authors: Christine Barul, Matthieu Carton, Loredana Radoï, Gwenn Menvielle, Corinne Pilorget, Simona Bara, Isabelle Stücker and Danièle Luce

    Citation: BMC Cancer 2018 18:388

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  3. Content type: Research article

    Breast cancer (BC) is the most common cancer in women worldwide and leading cause of cancer deaths indeveloping countries. There is very limited data on BC in the Central African Republic. The purpose of this ...

    Authors: Augustin Balekouzou, Ping Yin, Cavin Epi Bekolo, Christian Maucler Pamatika, Marceline Djeintote, Sylvain Wilfrid Nambei, Bertrand Ba-Mpoutou, Dieubeni Rawago Mandjiza, Chang Shu, Minghui Yin, Tingting Qing and Boniface Koffi

    Citation: BMC Cancer 2018 18:387

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  4. Content type: Research article

    Breast density is known to affect breast cancer risk and screening sensitivity, but it may also be associated with breast cancer survival. The interpretation of results from previous studies on breast density ...

    Authors: Daniëlle van der Waal, André L. M. Verbeek and Mireille J. M. Broeders

    Citation: BMC Cancer 2018 18:386

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  5. Content type: Research article

    Common cancer monitoring practice is seldom prospective and rather driven by public requests. This study aims to assess the performance of a recently developed prospective cancer monitoring method and the stat...

    Authors: Tammo Konstantin Reinders, Joachim Kieschke, Antje Timmer and Verena Jürgens

    Citation: BMC Cancer 2018 18:384

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  6. Content type: Research article

    With ongoing healthcare reform and shrinking numbers of oncologists, appropriate triaging of gynecologic cancer survivor care is crucial. Input from patients is a necessary part of this task. The objective of ...

    Authors: Matthew Schlumbrecht, Charlotte Sun, Marilyn Huang, Andrea Milbourne and Diane Bodurka

    Citation: BMC Cancer 2018 18:375

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  7. Content type: Research article

    Active smoking at the time of diagnosis of a first head & neck (H&N) or lung cancer is associated with a worse cancer outcome and increased mortality. However, the compared characteristics of active vs. former...

    Authors: Corinne Vannimenus, Hélène Bricout, Olivier Le Rouzic, François Mouawad, Dominique Chevalier, Eric Dansin, Laurence Rotsaert, Gautier Lefebvre, Olivier Cottencin, Henri Porte, Arnaud Scherpereel, Asmaa El Fahsi, Florence Richard and Benjamin Rolland

    Citation: BMC Cancer 2018 18:372

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  8. Content type: Research article

    Prostate cancer patients on androgen deprivation therapy (ADT) experience adverse effects such as lean mass loss, known as sarcopenia, fat gain, and changes in cardiometabolic factors that increase risk of met...

    Authors: Jacqueline K. Dawson, Tanya B. Dorff, E. Todd Schroeder, Christianne J. Lane, Mitchell E. Gross and Christina M. Dieli-Conwright

    Citation: BMC Cancer 2018 18:368

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  9. Content type: Research article

    Identifying preferences for stool collection devices may help increase uptake rates for colorectal cancer screening via fecal immunochemical test (FIT). This study surveyed satisfaction with different devices ...

    Authors: Hye Young Shin, Mina Suh, Kui Son Choi, Sang-Hyun Hwang, Jae Kwan Jun, Dong Soo Han, You Kyoung Lee, Jae Hwan Oh, Chan Wha Lee and Do-Hoon Lee

    Citation: BMC Cancer 2018 18:365

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  10. Content type: Research article

    Understanding what influences people to seek help can inform interventions to promote earlier diagnosis of cancer, and ultimately better cancer survival. We aimed to examine relationships between negative canc...

    Authors: Anette Fischer Pedersen, Lindsay Forbes, Kate Brain, Line Hvidberg, Christian Nielsen Wulff, Magdalena Lagerlund, Senada Hajdarevic, Samantha L. Quaife and Peter Vedsted

    Citation: BMC Cancer 2018 18:363

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  11. Content type: Research article

    The accumulated evidence has indicated the diagnostic role of cytokeratin (CK) and vimentin protein immunoassay in primary esophageal spindle cell carcinoma (PESC), which is a rare malignant tumor with epithel...

    Authors: Xin Min Li, Xin Song, Xue Ke Zhao, Shou Jia Hu, Rang Cheng, Shuang Lv, Dan Feng Du, Xiang Yang Zhang, Jian Liang Lu, Jian Wei Ku, Dong Yun Zhang, Yao Zhang, Zong Min Fan and Li Dong Wang

    Citation: BMC Cancer 2018 18:356

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  12. Content type: Research article

    Breast cancer survivors with excess weight are more likely to have negative breast cancer outcomes. Biomarkers related to insulin resistance may help explain this negative association. Weight loss is associate...

    Authors: Kim L. Dittus, Jean R. Harvey, Janice Y. Bunn, Nathan D. Kokinda, Karen M. Wilson, Jeff Priest and Richard E. Pratley

    Citation: BMC Cancer 2018 18:351

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  13. Content type: Research article

    Previous studies have indicated that people with malignant pleural mesothelioma (MPM) have a poor quality of life (QOL); however, information about the QOL of people with MPM in Japan is anecdotal. The aims of...

    Authors: Yasuko Nagamatsu, Isao Oze, Keisuke Aoe, Katsuyuki Hotta, Katsuya Kato, Junko Nakagawa, Keiko Hara, Takumi Kishimoto and Nobukazu Fujimoto

    Citation: BMC Cancer 2018 18:350

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  14. Content type: Research article

    Ovarian carcinoma is the most lethal gynecological malignancy due to early dissemination and acquired resistance to platinum-based chemotherapy. Reliable markers that are independent and complementary to clini...

    Authors: Cécile Le Page, Kurosh Rahimi, Martin Köbel, Patricia N. Tonin, Liliane Meunier, Lise Portelance, Monique Bernard, Brad H. Nelson, Marcus Q. Bernardini, John M. S. Bartlett, Dimcho Bachvarov, Walter H. Gotlieb, Blake Gilks, Jessica N. McAlpine, Mark W. Nachtigal, Alain Piché…

    Citation: BMC Cancer 2018 18:347

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  15. Content type: Research article

    The incidence and survival rates for colorectal cancer in Australia are among the highest in the world. With population growth and ageing there are increasing numbers of colorectal cancer survivors in the comm...

    Authors: Jane M. Young, Ivana Durcinoska, Katie DeLoyde and Michael J. Solomon

    Citation: BMC Cancer 2018 18:339

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  16. Content type: Research article

    Whether the emotional distress around cancer diagnosis is associated with the long-term outcomes and care utilization is unknown. We aimed to examine the association of mental disorders around cancer diagnosis...

    Authors: Jianwei Zhu, Arvid Sjölander, Katja Fall, Unnur Valdimarsdottir and Fang Fang

    Citation: BMC Cancer 2018 18:322

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  17. Content type: Research article

    The primary objective was to determine human papilloma virus (HPV) clearance rate after cervical biopsy among women with persistent high-risk HPV infection compared with spontaneous HPV clearance rate in the a...

    Authors: K. U. Petry, J. Horn, A. Luyten and R. T. Mikolajczyk

    Citation: BMC Cancer 2018 18:318

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  18. Content type: Research article

    Typically, women in South Africa (SA) are diagnosed with breast cancer when they self-present with symptoms to health facilities. The aim of this study was to determine the pathway that women follow to breast ...

    Authors: Jennifer Moodley, Lydia Cairncross, Thurandrie Naiker and Deborah Constant

    Citation: BMC Cancer 2018 18:312

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  19. Content type: Research article

    Tumor testing for mutations in the epidermal growth factor receptor (EGFR) gene is indicated for all newly diagnosed, metastatic lung cancer patients, who may be candidates for first-line treatment with an EGFR t...

    Authors: Julie A. Lynch, Brygida Berse, Merry Rabb, Paul Mosquin, Rob Chew, Suzanne L. West, Nicole Coomer, Daniel Becker and John Kautter

    Citation: BMC Cancer 2018 18:306

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  20. Content type: Research article

    The WHO recognises that community pharmacists are the most accessible healthcare professionals to the general public. Most patients regularly visit community pharmacies for health information and also seek adv...

    Authors: Kofi Boamah Mensah, Frasia Oosthuizen and Adwoa Bemah Bonsu

    Citation: BMC Cancer 2018 18:299

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  21. Content type: Research article

    Cervical cancer is one of the most easily preventable forms of female cancers if early screening and diagnosis is made. Low awareness level about the disease and risk factors, beliefs about the disease, poor a...

    Authors: Yitagesu Habtu, Samuel Yohannes and Tariku Laelago

    Citation: BMC Cancer 2018 18:298

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  22. Content type: Research article

    Thyroid cancer is the most common malignant disease of the endocrine system. Previous studies indicate a rapid increase in the incidence of thyroid cancer in recent decades, and this increase has aroused the g...

    Authors: Lingbin Du, Youqing Wang, Xiaohui Sun, Huizhang Li, Xinwei Geng, Minghua Ge and Yimin Zhu

    Citation: BMC Cancer 2018 18:291

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  23. Content type: Research article

    Epidemiological studies have clarified the potential associations between regular aspirin use and cancers. However, it remains controversial on whether aspirin use decreases the risk of cancers risks. Therefor...

    Authors: Yan Qiao, Tingting Yang, Yong Gan, Wenzhen Li, Chao Wang, Yanhong Gong and Zuxun Lu

    Citation: BMC Cancer 2018 18:288

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  24. Content type: Research article

    Reproductive factors are well known risk factors for breast cancer; however, little is known about how genetic variants in hormonal pathways interact with that relationship.

    Authors: Trinidad Dierssen-Sotos, Camilo Palazuelos-Calderón, José-Juan Jiménez-Moleón, Nuria Aragonés, Jone M. Altzibar, Gemma Castaño-Vinyals, Vicente Martín-Sanchez, Inés Gómez-Acebo, Marcela Guevara, Adonina Tardón, Beatriz Pérez-Gómez, Pilar Amiano, Victor Moreno, Antonio J. Molina, Jéssica Alonso-Molero, Conchi Moreno-Iribas…

    Citation: BMC Cancer 2018 18:280

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  25. Content type: Research article

    A number of studies have investigated the association between androgenic alopecia (AGA) and cancer risk, but they have yielded inconsistent results. Therefore, this study was conducted to explore this controve...

    Authors: Weijun Liang, Liuying Song, Zheng Peng, Yan Zou and Shengming Dai

    Citation: BMC Cancer 2018 18:279

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  26. Content type: Research article

    Cervical cancer screening participation remains insufficient in most countries. Our aim was to evaluate whether offering a HPV self-sampling kit, either mailed directly to the woman’s home or using timely opt-...

    Authors: Mette Tranberg, Bodil Hammer Bech, Jan Blaakær, Jørgen Skov Jensen, Hans Svanholm and Berit Andersen

    Citation: BMC Cancer 2018 18:273

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  27. Content type: Research article

    There is no international consensus up to which age women with a diagnosis of triple-negative breast cancer (TNBC) and no family history of breast or ovarian cancer should be offered genetic testing for germline

    Authors: Christoph Engel, Kerstin Rhiem, Eric Hahnen, Sibylle Loibl, Karsten E. Weber, Sabine Seiler, Silke Zachariae, Jan Hauke, Barbara Wappenschmidt, Anke Waha, Britta Blümcke, Marion Kiechle, Alfons Meindl, Dieter Niederacher, Claus R. Bartram, Dorothee Speiser…

    Citation: BMC Cancer 2018 18:265

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  28. Content type: Research article

    Cancer screening awareness and participation may be lower in low- and middle-income countries that lack established national screening programmes compared with those that do. We evaluated potential determinant...

    Authors: Sumadi L. Anwar, Gindo Tampubolon, Mieke Van Hemelrijck, Susanna H. Hutajulu, Johnathan Watkins and Wahyu Wulaningsih

    Citation: BMC Cancer 2018 18:208

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  29. Content type: Research article

    Between 2003 and 2010 digital mammography (DM) gradually replaced screen-film mammography (SFM) in the Dutch breast cancer screening programme (BCSP). Previous studies showed increases in detection rate (DR) a...

    Authors: Valérie D. V. Sankatsing, Jacques Fracheboud, Linda de Munck, Mireille J. M. Broeders, Nicolien T. van Ravesteyn, Eveline A. M. Heijnsdijk, André L. M. Verbeek, Johannes D. M. Otten, Ruud M. Pijnappel, Sabine Siesling and Harry J. de Koning

    Citation: BMC Cancer 2018 18:256

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  30. Content type: Research article

    Identifying female carriers of BRCA1 and BRCA2 mutations is imperative for prevention of ovarian cancer and breast cancer. There are five major histologic subtypes of ovarian cancer and high grade serous cancer (...

    Authors: Gillian E. Hanley, Jessica N. McAlpine, Dianne Miller, David Huntsman, Kasmintan A. Schrader, C. Blake Gilks and Gillian Mitchell

    Citation: BMC Cancer 2018 18:254

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  31. Content type: Research article

    Carers looking after someone with cancer often experience negative impacts on their own health. M-health interventions have been designed to provide information and support to patients and their carers. Howeve...

    Authors: Natalie Heynsbergh, Leila Heckel, Mari Botti and Patricia M. Livingston

    Citation: BMC Cancer 2018 18:244

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  32. Content type: Research article

    In recent years management practices in relation to low-risk papillary microcarcinoma (PMC) have been evolving with increased awareness of the potential overdiagnosis and overtreatment of PMCs, and guidelines ...

    Authors: Brooke Nickel, Juan P. Brito, Ray Moynihan, Alexandra Barratt, Susan Jordan and Kirsten McCaffery

    Citation: BMC Cancer 2018 18:242

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  33. Content type: Research article

    Consumption of very hot (> 65 °C) beverages is probably associated with increased risk of oesophageal cancer. First associations were reported for yerba mate and it was initially believed that high content of ...

    Authors: Alex O. Okaru, Anke Rullmann, Adriana Farah, Elvira Gonzalez de Mejia, Mariana C. Stern and Dirk W. Lachenmeier

    Citation: BMC Cancer 2018 18:236

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  34. Content type: Research article

    Gastroenterology Departments at hospitals within Australia receive thousands of General Practitioner (GP)-referral letters for gastrointestinal investigations every month. Many of these requests are for colono...

    Authors: Anton R. Lord, Lisa A. Simms, Allison Brown, Katherine Hanigan, Krupa Krishnaprasad, Belinda Schouten, Anthony R. Croft, Mark N. Appleyard and Graham L. Radford-Smith

    Citation: BMC Cancer 2018 18:229

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  35. Content type: Research article

    Aspirin has been proposed as a novel adjuvant agent in colorectal cancer (CRC). Six observational studies have reported CRC-specific survival outcomes in patients using aspirin after CRC diagnosis but the resu...

    Authors: Ronan T. Gray, Helen G. Coleman, Carmel Hughes, Liam J. Murray and Chris R. Cardwell

    Citation: BMC Cancer 2018 18:228

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  36. Content type: Research article

    The centralisation of specialist cancer surgical services across London Cancer and Greater Manchester Cancer, England, may significantly change how patients experience care. These centres are changing specialist ...

    Authors: Mariya Melnychuk, Cecilia Vindrola-Padros, Michael Aitchison, Caroline S. Clarke, Naomi J. Fulop, Claire Levermore, Satish B. Maddineni, Caroline M. Moore, Muntzer M. Mughal, Catherine Perry, Kathy Pritchard-Jones, Angus I. G. Ramsay, David Shackley, Jonathan Vickers and Stephen Morris

    Citation: BMC Cancer 2018 18:226

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  37. Content type: Research article

    The insulin receptor (INSR) and the insulin growth factor 1 receptor (IGF1R) play important roles in the etiology of both diabetes mellitus and breast cancer. We aimed to evaluate the expression of hormone and...

    Authors: Heleen K. Bronsveld, Marie L. De Bruin, Jelle Wesseling, Joyce Sanders, Ingrid Hofland, Vibeke Jensen, Marloes T. Bazelier, Bas ter Braak, Anthonius de Boer, Peter Vestergaard and Marjanka K. Schmidt

    Citation: BMC Cancer 2018 18:224

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  38. Content type: Research article

    Obesity has been proposed as a potential protective factor against lung cancer. We examined the association between BMI and lung cancer risk in a pooled analysis based on nested case-control studies from four ...

    Authors: Harinakshi Sanikini, Jian-Min Yuan, Lesley M. Butler, Woon-Puay Koh, Yu-Tang Gao, Annika Steffen, Mattias Johansson, Paolo Vineis, Gary E. Goodman, Matt J. Barnett, Rayjean J. Hung, Chu Chen and Isabelle Stücker

    Citation: BMC Cancer 2018 18:220

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  39. Content type: Research article

    Aberrant crypt foci (ACF) are commonly considered the early pre-cancerous lesions that can progress to colorectal cancer (CRC). The available literature data reveal that age, dietary factors and lifestyle can ...

    Authors: Marek Kowalczyk, Marcin Orłowski, Piotr Siermontowski, Dariusz Mucha, Krzysztof Zinkiewicz, Waldemar Kurpiewski, Ewa Zieliński, Iwona Kowalczyk and Agnieszka Pedrycz

    Citation: BMC Cancer 2018 18:213

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  40. Content type: Research article

    Mammography screening is used to detect breast cancer at an early treatable stage, reducing breast cancer mortality. Traditionally, breast cancer has been seen as a disease with only progressive lesions, and h...

    Authors: Åsbjørn Schumacher Westvik, Harald Weedon-Fekjær, Jan Mæhlen and Knut Liestøl

    Citation: BMC Cancer 2018 18:209

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  41. Content type: Research article

    Improvements in detection and treatment of prostate cancer (PCa) translate into more men living with PCa, who are therefore potentially at risk of a secondly diagnosed primary tumour (SDPTs). Little is known a...

    Authors: Cecilia Bosco, Hans Garmo, Niklas Hammar, Göran Walldius, Ingmar Jungner, Håkan Malmström, Lars Holmberg and Mieke Van Hemelrijck

    Citation: BMC Cancer 2018 18:205

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  42. Content type: Research article

    Subjects with elevated Epstein-Barr virus (EBV) immunoglobulin A (IgA) titers have a higher risk of developing nasopharyngeal carcinoma (NPC), indicating that reactivation of EBV in the local mucosa might be i...

    Authors: Yufeng Chen, Yifei Xu, Weilin Zhao, Xue Xiao, Xiaoying Zhou, Longde Lin, Tingting Huang, Jian Liao, Yancheng Li, Xiaoyun Zeng, Guangwu Huang, Weimin Ye and Zhe Zhang

    Citation: BMC Cancer 2018 18:190

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