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Epidemiology, prevention and public health

This section aims to consider publications which focus on all aspects of cancer epidemiology including risk factors for disease initiation and development, social determinants, environmental, behavioural, and occupational correlates, and the impact of health policies, practices and interventions on the community.

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  1. Content type: Research article

    The fecal immunochemical test (FIT) is easier to use and more sensitive than the guaiac fecal occult blood test, but it is unclear how to optimize FIT performance. We compared the sensitivity and specificity f...

    Authors: Elizabeth G. Liles, Nancy Perrin, Ana G. Rosales, David H. Smith, Adrianne C. Feldstein, David M. Mosen and Theodore R. Levin

    Citation: BMC Cancer 2018 18:509

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  2. Content type: Research article

    In the United States, race and socioeconomic status are well known predictors of adverse outcomes in several different cancers. Existing evidence suggests that race and socioeconomic status may impact survival...

    Authors: Alexander L. Lazarides, Julia D. Visgauss, Daniel P. Nussbaum, Cindy L. Green, Dan G. Blazer III, Brian E. Brigman and William C. Eward

    Citation: BMC Cancer 2018 18:488

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  3. Content type: Research article

    This study aimed to provide more information for cancer prevention strategies by determining the distribution of human papilloma virus (HPV) genotype prevalence in invasive cervical carcinoma (ICC) and precanc...

    Authors: Hongyun WANG, Xiaodong CHENG, Jing YE, Xiuyun XU, Ying HONG, Long SUI, Zhixue YOU and Xing XIE

    Citation: BMC Cancer 2018 18:487

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  4. Content type: Research article

    A gradual decline in the incidence of breast cancer is documented in developed countries especially over last two decades, while in developing countries the incidence continues to rise. We conducted this study...

    Authors: Ashan Fernando, Umesh Jayarajah, Saumyakala Prabashani, Eshani A. Fernando and Sanjeewa A. Seneviratne

    Citation: BMC Cancer 2018 18:482

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  5. Content type: Research article

    Surveillance, Epidemiology, and End Results (SEER) public research database does not include chemotherapy data due to concerns for incomplete ascertainment. To compensate for perceived lack of data quality man...

    Authors: Mark A. Healy, Arden M. Morris, Paul Abrahamse, Kevin C. Ward, Ikuko Kato and Christine M. Veenstra

    Citation: BMC Cancer 2018 18:481

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  6. Content type: Research article

    Both the adenoma detection rate (ADR) and proximal serrated polyp detection rate (PSPDR) vary among endoscopists. It is unclear how these variations influence colorectal cancer (CRC) screening effectiveness. W...

    Authors: Maxime E. S. Bronzwaer, Marjolein J. E. Greuter, Arne G. C. Bleijenberg, Joep E. G. IJspeert, Evelien Dekker and Veerle M. H. Coupé

    Citation: BMC Cancer 2018 18:465

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  7. Content type: Research article

    The Basque Colorectal Cancer Screening Programme began in 2009 and the implementation has been complete since 2013. Faecal immunological testing was used for screening in individuals between 50 and 69 years ol...

    Authors: Arantzazu Arrospide, Isabel Idigoras, Javier Mar, Harry de Koning, Miriam van der Meulen, Myriam Soto-Gordoa, Jose Miguel Martinez-Llorente, Isabel Portillo, Eunate Arana-Arri, Oliver Ibarrondo and Iris Lansdorp-Vogelaar

    Citation: BMC Cancer 2018 18:464

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  8. Content type: Research article

    Survival rates for upper gastrointestinal (GI) cancer are poor since many are diagnosed at advanced stages. Fast track endoscopy has been introduced to prompt diagnosis for patients with alarm symptoms that co...

    Authors: Sanne Rasmussen, Peter Fentz Haastrup, Kirubakaran Balasubramaniam, René DePont Christensen, Jens Søndergaard and Dorte Ejg Jarbøl

    Citation: BMC Cancer 2018 18:440

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  9. Content type: Research article

    In China, stomach cancer is the third most common cancer and the third leading cause of cancer death. Few studies have examined Chinese stomach cancer patients’ medical expenses and their associated trends. Th...

    Authors: Xiao-Jie Sun, Ju-Fang Shi, Lan-Wei Guo, Hui-Yao Huang, Neng-Liang Yao, Ji-Yong Gong, Ya-Wen Sun, Guo-Xiang Liu, A-Yan Mao, Xian-Zhen Liao, Ya-Na Bai, Jian-Song Ren, Xin-Yu Zhu, Jin-Yi Zhou, Ling Mai, Bing-Bing Song…

    Citation: BMC Cancer 2018 18:435

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  10. Content type: Debate

    The Sarcoma Policy Checklist was created by a multidisciplinary expert group to provide policymakers with priority areas to improve care for sarcoma patients.

    Authors: Bernd Kasper, Estelle Lecointe-Artzner, Suzanne Wait, Shannon Boldon, Roger Wilson, Alessandro Gronchi, Claudia Valverde, Mikael Eriksson, Sarah Dumont, Nora Drove, Athanasia Kanli and Markus Wartenberg

    Citation: BMC Cancer 2018 18:424

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  11. Content type: Research article

    The increasing epidemic proportions of diabetes mellitus (DM) are a major cause of premature illness and death. However, whether DM confers the same excess risk of gastrointestinal cancer for women as it does ...

    Authors: Hong-juan FANG, Shao-bo SHAN, Yu-hao ZHOU and Li-yong ZHONG

    Citation: BMC Cancer 2018 18:422

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  12. Content type: Research article

    Patients with the myeloproliferative neoplasms (MPNs) myelofibrosis (MF), polycythemia vera (PV), and essential thrombocythemia (ET) are at increased risk for thrombotic and cardiovascular events and experienc...

    Authors: Jingbo Yu, Shreekant Parasuraman, Dilan Paranagama, Andrew Bai, Ahmad Naim, David Dubinski and Ruben Mesa

    Citation: BMC Cancer 2018 18:420

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  13. Content type: Research article

    Although acute oxaliplatin-induced neuropathy (OXIPN) is frequently regarded to be transient, recent studies have reported prolongation of infusion times, dose reduction and treatment cessation following the f...

    Authors: Endale Gebreegziabher Gebremedhn, Peter John Shortland and David Anthony Mahns

    Citation: BMC Cancer 2018 18:410

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  14. Content type: Research article

    Cancer registry data show that survival of colorectal cancer (CRC) in the United Kingdom is poor compared with other European countries and the United States, yet these data sources lack information on patient...

    Authors: Lucía Cea Soriano, Montse Soriano-Gabarró and Luis A. García Rodríguez

    Citation: BMC Cancer 2018 18:402

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  15. Content type: Research article

    Research has revealed that angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) may prevent cancers such as hepatocellular carcinoma (HCC). The comparative chemopreventi...

    Authors: Cheng-Maw Ho, Chih-Hsin Lee, Ming-Chia Lee, Jun-Fu Zhang, Jann-Yuan Wang, Rey-Heng Hu and Po-Huang Lee

    Citation: BMC Cancer 2018 18:401

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  16. Content type: Research article

    Studies on alternative routes to diagnosis stimulated successful policy interventions reducing the number of emergency diagnoses and associated mortality risk. A dearth of evidence on the costs of such interve...

    Authors: Mauro Laudicella, Brendan Walsh, Elaine Burns, Paolo Li Donni and Peter C. Smith

    Citation: BMC Cancer 2018 18:394

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  17. Content type: Research article

    To examine associations between occupational exposure to petroleum-based and oxygenated solvents and the risk of hypopharyngeal and laryngeal cancer.

    Authors: Christine Barul, Matthieu Carton, Loredana Radoï, Gwenn Menvielle, Corinne Pilorget, Simona Bara, Isabelle Stücker and Danièle Luce

    Citation: BMC Cancer 2018 18:388

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  18. Content type: Research article

    Breast cancer (BC) is the most common cancer in women worldwide and leading cause of cancer deaths indeveloping countries. There is very limited data on BC in the Central African Republic. The purpose of this ...

    Authors: Augustin Balekouzou, Ping Yin, Cavin Epi Bekolo, Christian Maucler Pamatika, Marceline Djeintote, Sylvain Wilfrid Nambei, Bertrand Ba-Mpoutou, Dieubeni Rawago Mandjiza, Chang Shu, Minghui Yin, Tingting Qing and Boniface Koffi

    Citation: BMC Cancer 2018 18:387

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  19. Content type: Research article

    Breast density is known to affect breast cancer risk and screening sensitivity, but it may also be associated with breast cancer survival. The interpretation of results from previous studies on breast density ...

    Authors: Daniëlle van der Waal, André L. M. Verbeek and Mireille J. M. Broeders

    Citation: BMC Cancer 2018 18:386

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  20. Content type: Research article

    Common cancer monitoring practice is seldom prospective and rather driven by public requests. This study aims to assess the performance of a recently developed prospective cancer monitoring method and the stat...

    Authors: Tammo Konstantin Reinders, Joachim Kieschke, Antje Timmer and Verena Jürgens

    Citation: BMC Cancer 2018 18:384

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  21. Content type: Research article

    With ongoing healthcare reform and shrinking numbers of oncologists, appropriate triaging of gynecologic cancer survivor care is crucial. Input from patients is a necessary part of this task. The objective of ...

    Authors: Matthew Schlumbrecht, Charlotte Sun, Marilyn Huang, Andrea Milbourne and Diane Bodurka

    Citation: BMC Cancer 2018 18:375

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  22. Content type: Research article

    Active smoking at the time of diagnosis of a first head & neck (H&N) or lung cancer is associated with a worse cancer outcome and increased mortality. However, the compared characteristics of active vs. former...

    Authors: Corinne Vannimenus, Hélène Bricout, Olivier Le Rouzic, François Mouawad, Dominique Chevalier, Eric Dansin, Laurence Rotsaert, Gautier Lefebvre, Olivier Cottencin, Henri Porte, Arnaud Scherpereel, Asmaa El Fahsi, Florence Richard and Benjamin Rolland

    Citation: BMC Cancer 2018 18:372

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  23. Content type: Research article

    Prostate cancer patients on androgen deprivation therapy (ADT) experience adverse effects such as lean mass loss, known as sarcopenia, fat gain, and changes in cardiometabolic factors that increase risk of met...

    Authors: Jacqueline K. Dawson, Tanya B. Dorff, E. Todd Schroeder, Christianne J. Lane, Mitchell E. Gross and Christina M. Dieli-Conwright

    Citation: BMC Cancer 2018 18:368

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  24. Content type: Research article

    Identifying preferences for stool collection devices may help increase uptake rates for colorectal cancer screening via fecal immunochemical test (FIT). This study surveyed satisfaction with different devices ...

    Authors: Hye Young Shin, Mina Suh, Kui Son Choi, Sang-Hyun Hwang, Jae Kwan Jun, Dong Soo Han, You Kyoung Lee, Jae Hwan Oh, Chan Wha Lee and Do-Hoon Lee

    Citation: BMC Cancer 2018 18:365

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  25. Content type: Research article

    Understanding what influences people to seek help can inform interventions to promote earlier diagnosis of cancer, and ultimately better cancer survival. We aimed to examine relationships between negative canc...

    Authors: Anette Fischer Pedersen, Lindsay Forbes, Kate Brain, Line Hvidberg, Christian Nielsen Wulff, Magdalena Lagerlund, Senada Hajdarevic, Samantha L. Quaife and Peter Vedsted

    Citation: BMC Cancer 2018 18:363

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  26. Content type: Research article

    The accumulated evidence has indicated the diagnostic role of cytokeratin (CK) and vimentin protein immunoassay in primary esophageal spindle cell carcinoma (PESC), which is a rare malignant tumor with epithel...

    Authors: Xin Min Li, Xin Song, Xue Ke Zhao, Shou Jia Hu, Rang Cheng, Shuang Lv, Dan Feng Du, Xiang Yang Zhang, Jian Liang Lu, Jian Wei Ku, Dong Yun Zhang, Yao Zhang, Zong Min Fan and Li Dong Wang

    Citation: BMC Cancer 2018 18:356

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  27. Content type: Research article

    Breast cancer survivors with excess weight are more likely to have negative breast cancer outcomes. Biomarkers related to insulin resistance may help explain this negative association. Weight loss is associate...

    Authors: Kim L. Dittus, Jean R. Harvey, Janice Y. Bunn, Nathan D. Kokinda, Karen M. Wilson, Jeff Priest and Richard E. Pratley

    Citation: BMC Cancer 2018 18:351

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  28. Content type: Research article

    Previous studies have indicated that people with malignant pleural mesothelioma (MPM) have a poor quality of life (QOL); however, information about the QOL of people with MPM in Japan is anecdotal. The aims of...

    Authors: Yasuko Nagamatsu, Isao Oze, Keisuke Aoe, Katsuyuki Hotta, Katsuya Kato, Junko Nakagawa, Keiko Hara, Takumi Kishimoto and Nobukazu Fujimoto

    Citation: BMC Cancer 2018 18:350

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  29. Content type: Research article

    Ovarian carcinoma is the most lethal gynecological malignancy due to early dissemination and acquired resistance to platinum-based chemotherapy. Reliable markers that are independent and complementary to clini...

    Authors: Cécile Le Page, Kurosh Rahimi, Martin Köbel, Patricia N. Tonin, Liliane Meunier, Lise Portelance, Monique Bernard, Brad H. Nelson, Marcus Q. Bernardini, John M. S. Bartlett, Dimcho Bachvarov, Walter H. Gotlieb, Blake Gilks, Jessica N. McAlpine, Mark W. Nachtigal, Alain Piché…

    Citation: BMC Cancer 2018 18:347

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  30. Content type: Research article

    The incidence and survival rates for colorectal cancer in Australia are among the highest in the world. With population growth and ageing there are increasing numbers of colorectal cancer survivors in the comm...

    Authors: Jane M. Young, Ivana Durcinoska, Katie DeLoyde and Michael J. Solomon

    Citation: BMC Cancer 2018 18:339

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  31. Content type: Research article

    Whether the emotional distress around cancer diagnosis is associated with the long-term outcomes and care utilization is unknown. We aimed to examine the association of mental disorders around cancer diagnosis...

    Authors: Jianwei Zhu, Arvid Sjölander, Katja Fall, Unnur Valdimarsdottir and Fang Fang

    Citation: BMC Cancer 2018 18:322

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  32. Content type: Research article

    The primary objective was to determine human papilloma virus (HPV) clearance rate after cervical biopsy among women with persistent high-risk HPV infection compared with spontaneous HPV clearance rate in the a...

    Authors: K. U. Petry, J. Horn, A. Luyten and R. T. Mikolajczyk

    Citation: BMC Cancer 2018 18:318

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  33. Content type: Research article

    Typically, women in South Africa (SA) are diagnosed with breast cancer when they self-present with symptoms to health facilities. The aim of this study was to determine the pathway that women follow to breast ...

    Authors: Jennifer Moodley, Lydia Cairncross, Thurandrie Naiker and Deborah Constant

    Citation: BMC Cancer 2018 18:312

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  34. Content type: Research article

    Tumor testing for mutations in the epidermal growth factor receptor (EGFR) gene is indicated for all newly diagnosed, metastatic lung cancer patients, who may be candidates for first-line treatment with an EGFR t...

    Authors: Julie A. Lynch, Brygida Berse, Merry Rabb, Paul Mosquin, Rob Chew, Suzanne L. West, Nicole Coomer, Daniel Becker and John Kautter

    Citation: BMC Cancer 2018 18:306

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  35. Content type: Research article

    The WHO recognises that community pharmacists are the most accessible healthcare professionals to the general public. Most patients regularly visit community pharmacies for health information and also seek adv...

    Authors: Kofi Boamah Mensah, Frasia Oosthuizen and Adwoa Bemah Bonsu

    Citation: BMC Cancer 2018 18:299

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  36. Content type: Research article

    Cervical cancer is one of the most easily preventable forms of female cancers if early screening and diagnosis is made. Low awareness level about the disease and risk factors, beliefs about the disease, poor a...

    Authors: Yitagesu Habtu, Samuel Yohannes and Tariku Laelago

    Citation: BMC Cancer 2018 18:298

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  37. Content type: Research article

    Thyroid cancer is the most common malignant disease of the endocrine system. Previous studies indicate a rapid increase in the incidence of thyroid cancer in recent decades, and this increase has aroused the g...

    Authors: Lingbin Du, Youqing Wang, Xiaohui Sun, Huizhang Li, Xinwei Geng, Minghua Ge and Yimin Zhu

    Citation: BMC Cancer 2018 18:291

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  38. Content type: Research article

    Epidemiological studies have clarified the potential associations between regular aspirin use and cancers. However, it remains controversial on whether aspirin use decreases the risk of cancers risks. Therefor...

    Authors: Yan Qiao, Tingting Yang, Yong Gan, Wenzhen Li, Chao Wang, Yanhong Gong and Zuxun Lu

    Citation: BMC Cancer 2018 18:288

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  39. Content type: Research article

    Reproductive factors are well known risk factors for breast cancer; however, little is known about how genetic variants in hormonal pathways interact with that relationship.

    Authors: Trinidad Dierssen-Sotos, Camilo Palazuelos-Calderón, José-Juan Jiménez-Moleón, Nuria Aragonés, Jone M. Altzibar, Gemma Castaño-Vinyals, Vicente Martín-Sanchez, Inés Gómez-Acebo, Marcela Guevara, Adonina Tardón, Beatriz Pérez-Gómez, Pilar Amiano, Victor Moreno, Antonio J. Molina, Jéssica Alonso-Molero, Conchi Moreno-Iribas…

    Citation: BMC Cancer 2018 18:280

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  40. Content type: Research article

    A number of studies have investigated the association between androgenic alopecia (AGA) and cancer risk, but they have yielded inconsistent results. Therefore, this study was conducted to explore this controve...

    Authors: Weijun Liang, Liuying Song, Zheng Peng, Yan Zou and Shengming Dai

    Citation: BMC Cancer 2018 18:279

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  41. Content type: Research article

    Cervical cancer screening participation remains insufficient in most countries. Our aim was to evaluate whether offering a HPV self-sampling kit, either mailed directly to the woman’s home or using timely opt-...

    Authors: Mette Tranberg, Bodil Hammer Bech, Jan Blaakær, Jørgen Skov Jensen, Hans Svanholm and Berit Andersen

    Citation: BMC Cancer 2018 18:273

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  42. Content type: Research article

    There is no international consensus up to which age women with a diagnosis of triple-negative breast cancer (TNBC) and no family history of breast or ovarian cancer should be offered genetic testing for germline

    Authors: Christoph Engel, Kerstin Rhiem, Eric Hahnen, Sibylle Loibl, Karsten E. Weber, Sabine Seiler, Silke Zachariae, Jan Hauke, Barbara Wappenschmidt, Anke Waha, Britta Blümcke, Marion Kiechle, Alfons Meindl, Dieter Niederacher, Claus R. Bartram, Dorothee Speiser…

    Citation: BMC Cancer 2018 18:265

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