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Epidemiology, prevention and public health

Section edited by Manami Inoue

This section aims to consider publications which focus on all aspects of cancer epidemiology including risk factors for disease initiation and development, social determinants, environmental, behavioural, and occupational correlates, and the impact of health policies, practices and interventions on the community.

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  1. Content type: Research article

    The rs2282679 A>C polymorphism in the vitamin D binding protein gene is associated with lower circulating levels of vitamin D. We investigated associations of this SNP with colorectal cancer (CRC) risk and sur...

    Authors: Yun Zhu, Peizhong Peter Wang, Guangju Zhai, Bharati Bapat, Sevtap Savas, Jennifer R. Woodrow, Peter T. Campbell, Yuming Li, Ning Yang, Xin Zhou, Elizabeth Dicks, John R. Mclaughlin and Patrick S. Parfrey

    Citation: BMC Cancer 2018 18:155

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  2. Content type: Research article

    We evaluated treatment decisions and outcomes in a cohort of predominately Caucasian patients with EGFR mutation-positive (EGFR Mut+) non-small-cell lung cancer (NSCLC).

    Authors: Wolfgang Schuette, Peter Schirmacher, Wilfried E. E. Eberhardt, Manfred Dietel, Ute Zirrgiebel, Lars Muehlenhoff and Michael Thomas

    Citation: BMC Cancer 2018 18:135

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  3. Content type: Research article

    It has been suggested that distal gastric carcinoma (GC) in younger patients has a more aggressive outcome than in older patients, however this is a controversial issue. The aim of this study was to compare cl...

    Authors: Manuel B. Braga-Neto, Jessica Gomes Carneiro, Alzira M. de Castro Barbosa, Igor S. Silva, Danielle C. Maia, Felipe S. Maciel, Rafael Jorge Alves de Alcântara, Paulo Roberto L. Vasconscelos and Lucia L. B. C. Braga

    Citation: BMC Cancer 2018 18:131

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  4. Content type: Research article

    Quality indicators for the Brazilian cervical cancer screening programme can provide a perspective on its effectiveness in Brazilian macro-regions and states. The aim of this study was to perform a trend analy...

    Authors: Ricardo Filipe Alves Costa, Adhemar Longatto-Filho, Fabiana de Lima Vazquez, Céline Pinheiro, Luiz Carlos Zeferino and José Humberto Tavares Guerreiro Fregnani

    Citation: BMC Cancer 2018 18:126

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  5. Content type: Research article

    Patients with primary brain tumors are reported to have an elevated level of distress prevalence, due to the functional sequelae and the unfavorable prognosis, but the estimated prevalence of this disorder var...

    Authors: Fangkun Liu, Jing Huang, Liyang Zhang, Fan Fan, Jindong Chen, Kun Xia and Zhixiong Liu

    Citation: BMC Cancer 2018 18:124

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  6. Content type: Research article

    Lung cancer is the leading cause of cancer-related mortality in Utah despite having the nation’s lowest smoking rate. Radon exposure and differences in lung cancer incidence between nonmetropolitan and metropo...

    Authors: Judy Y. Ou, Brynn Fowler, Qian Ding, Anne C. Kirchhoff, Lisa Pappas, Kenneth Boucher, Wallace Akerley, Yelena Wu, Kimberly Kaphingst, Garrett Harding and Deanna Kepka

    Citation: BMC Cancer 2018 18:115

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  7. Content type: Research article

    Breast cancer survivors are at high risk for fracture due to cancer treatment-induced bone loss, however, data is scarce regarding the scope of this problem from an epidemiologic and health services perspectiv...

    Authors: Evelyn Hsieh, Qin Wang, Renzhi Zhang, Xin Niu, Weibo Xia, Liana Fraenkel, Karl L. Insogna, Jing Li, Jennifer S. Smith, Chunwu Zhou, You-lin Qiao and Pin Zhang

    Citation: BMC Cancer 2018 18:104

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  8. Content type: Research article

    Surveys indicate quite high prevalence of cancer worry in the general population, but little is known about what it is about cancer that worries people. A better understanding of the origins of cancer worry ma...

    Authors: Philippa J. Murphy, Laura A. V. Marlow, Jo Waller and Charlotte Vrinten

    Citation: BMC Cancer 2018 18:86

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  9. Content type: Research article

    This study explores the effectiveness and cost-effectiveness of surveillance after breast cancer treatment provided in a hospital-setting versus surveillance embedded in the community-based National Breast Can...

    Authors: Kelly M. de Ligt, Annemieke Witteveen, Sabine Siesling and Lotte M. G. Steuten

    Citation: BMC Cancer 2018 18:96

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  10. Content type: Research article

    Deaf people represent 0.1% of the French population and their access to public health campaigns is limited due to their frequent illiteracy and the infrequent use of sign language in campaigns. There is also a...

    Authors: Vladimir Druel, Hélène Hayet, Laetitia Esman, Marie Clavel and Marie-Eve Rougé Bugat

    Citation: BMC Cancer 2018 18:93

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  11. Content type: Research article

    There is ongoing debate about the harms and benefits of a national prostate cancer screening programme. Several model-based cost-effectiveness analyses have been developed to determine whether the benefits of ...

    Authors: Sabina Sanghera, Joanna Coast, Richard M. Martin, Jenny L. Donovan and Syed Mohiuddin

    Citation: BMC Cancer 2018 18:84

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  12. Content type: Research article

    We evaluated the incidence and spectrum of pathogenic and likely pathogenic variants of cancer susceptibility genes in BRCA1/2 mutation-negative Korean patients with a high risk for hereditary breast cancer using...

    Authors: Ji Soo Park, Seung-Tae Lee, Eun Ji Nam, Jung Woo Han, Jung-Yun Lee, Jieun Kim, Tae Il Kim and Hyung Seok Park

    Citation: BMC Cancer 2018 18:83

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  13. Content type: Research article

    Obesity has been reported as an adverse prognostic factor in breast cancer, but inconsistently, and under-treatment with chemotherapy may occur. We provide the first assessment of obesity and breast cancer out...

    Authors: J. Mark Elwood, Sandar Tin Tin, Marion Kuper-Hommel, Ross Lawrenson and Ian Campbell

    Citation: BMC Cancer 2018 18:76

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  14. Content type: Research article

    Physical activity is consistently associated with a reduced risk of colorectal cancer in epidemiologic studies. This association among higher risk subgroups, such as those with a first-degree family history of...

    Authors: Eileen Shaw, Megan S. Farris, Chelsea R. Stone, Jeroen W. G. Derksen, Rhys Johnson, Robert J. Hilsden, Christine M. Friedenreich and Darren R. Brenner

    Citation: BMC Cancer 2018 18:71

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  15. Content type: Research article

    To assess the factorial structure, internal consistency, construct validity and reproducibility of the Quality of Working Life Questionnaire for Cancer Survivors (QWLQ-CS).

    Authors: Merel de Jong, Sietske J. Tamminga, Robert J. J. van Es, Monique H. W. Frings-Dresen and Angela G. E. M. de Boer

    Citation: BMC Cancer 2018 18:66

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  16. Content type: Research article

    Metformin is associated with a reduced risk of some cancers but its effect on prostate cancer is unclear. Some studies suggest only Asians derive this benefit. Therefore, we undertook a systematic review with ...

    Authors: Christopher B. Chen, Maxim Eskin, Dean T. Eurich, Sumit R. Majumdar and Jeffrey A. Johnson

    Citation: BMC Cancer 2018 18:65

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  17. Content type: Study protocol

    Though breast cancer remains a major health problem, there is a lack of information on health care provided to patients with this disease and associated costs. In addition, there is a need to update and valida...

    Authors: Susana García-Gutierrez, Miren Orive, Cristina Sarasqueta, Maria Jose Legarreta, Nerea Gonzalez, Maximino Redondo, Amado Rivero, Pedro Serrano-Aguilar, Xavier Castells, Jose Maria Quintana and Maria Sala

    Citation: BMC Cancer 2018 18:54

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  18. Content type: Research article

    New Zealand has major ethnic disparities in breast cancer survival with Māori (indigenous people) and Pacific women (immigrants or descended from immigrants from Pacific Islands) faring much worse than other e...

    Authors: Sandar Tin Tin, J. Mark Elwood, Charis Brown, Diana Sarfati, Ian Campbell, Nina Scott, Reena Ramsaroop, Sanjeewa Seneviratne, Vernon Harvey and Ross Lawrenson

    Citation: BMC Cancer 2018 18:58

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  19. Content type: Research article

    Informal caregivers provide extended support to people with cancer but they receive little support from the health care system to assist them in their caring role. The aim of this single-blind, multi-centre, r...

    Authors: Leila Heckel, Kate M. Fennell, John Reynolds, Anna Boltong, Mari Botti, Richard H. Osborne, Cathrine Mihalopoulos, Jacquie Chirgwin, Melinda Williams, Cadeyrn J. Gaskin, David M. Ashley and Patricia M. Livingston

    Citation: BMC Cancer 2018 18:59

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  20. Content type: Research article

    To provide further information on the clinical and pathological prognostic factors in triple-negative breast cancer (TNBC), for which limited and inconsistent data are available.

    Authors: Silvana Anna Maria Urru, Silvano Gallus, Cristina Bosetti, Tiziana Moi, Ricardo Medda, Elisabetta Sollai, Alma Murgia, Francesca Sanges, Giovanna Pira, Alessandra Manca, Dolores Palmas, Matteo Floris, Anna Maria Asunis, Francesco Atzori, Ciriaco Carru, Maurizio D’Incalci…

    Citation: BMC Cancer 2018 18:56

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  21. Content type: Research article

    Bone metastases commonly occur in conjunction with solid tumors, and are associated with serious bone complications. Population-based estimates of bone metastasis incidence are limited, often based on autopsy ...

    Authors: Rohini K. Hernandez, Sally W. Wade, Adam Reich, Melissa Pirolli, Alexander Liede and Gary H. Lyman

    Citation: BMC Cancer 2018 18:44

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  22. Content type: Research article

    Interventions to improve fecal testing for colorectal cancer (CRC) exist, but are not yet routine practice. We conducted this systematic review to determine how implementation strategies and contextual factors...

    Authors: Melinda M. Davis, Michele Freeman, Jackilen Shannon, Gloria D. Coronado, Kurt C. Stange, Jeanne-Marie Guise, Stephanie B. Wheeler and David I. Buckley

    Citation: BMC Cancer 2018 18:40

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  23. Content type: Research article

    The objective of this study is to develop, implement, and evaluate a training program for healthcare providers to improve ability to provide psychosocial support to breast cancer survivors in Korea.

    Authors: Eunyoung Park, Junghee Yoon, Eun-kyung Choi, Im Ryung Kim, Danbee Kang, Se-Kyung Lee, Jeong Eon Lee, Seok Jin Nam, Jin Seok Ahn, Adriaan Visser and Juhee Cho

    Citation: BMC Cancer 2018 18:45

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  24. Content type: Research article

    Colorectal cancer is the 4th common cancer in China. Most colorectal cancers are due to modifiable lifestyle factors, but few studies have provided a systematic evidence-based assessment of the burden of color...

    Authors: Meng-Jia Gu, Qiu-Chi Huang, Cheng-Zhen Bao, Ying-Jun Li, Xiao-Qin Li, Ding Ye, Zhen-Hua Ye, Kun Chen and Jian-Bing Wang

    Citation: BMC Cancer 2018 18:38

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  25. Content type: Research article

    Breast cancer has a high case fatality rate in sub-Saharan Africa, and this is chiefly because of late detection and inadequate treatment resources. Progressive renovations in diagnostic and management modalit...

    Authors: Bibiana Ateh Nzeangung, Martin Essomba Biwole, Benjamin Momo Kadia, Ndemazie Nkafu Bechem, Christian Akem Dimala and Albert Mouelle Sone

    Citation: BMC Cancer 2018 18:32

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  26. Content type: Research article

    The goal of this exploratory study was to develop and assess a prediction model which can potentially be used as a biomarker of breast cancer, based on anthropometric data and parameters which can be gathered ...

    Authors: Miguel Patrício, José Pereira, Joana Crisóstomo, Paulo Matafome, Manuel Gomes, Raquel Seiça and Francisco Caramelo

    Citation: BMC Cancer 2018 18:29

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  27. Content type: Research article

    Body image is a complex post-treatment concern among female patients with breast cancer, and various tools have been developed and applied to measure this multifaceted issue. However, these available tools wer...

    Authors: Kaina Zhou, Xiaole He, Lanting Huo, Jinghua An, Minjie Li, Wen Wang and Xiaomei Li

    Citation: BMC Cancer 2018 18:19

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  28. Content type: Research article

    Though the incidence of Testicular cancer among young is rising, little attention is given to promoting testicular self-examination which is recommended for its early prevention in developing countries. This stud...

    Authors: Hordofa Gutema, Yamrot Debela, Bizuayehu Walle, Kidist Reba and Habtamu Wondiye

    Citation: BMC Cancer 2018 18:21

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  29. Content type: Research article

    We examined incidence and survival in relation to age, gender, socioeconomic deprivation, rurality and trends over time. We also examined the association between volume of patients treated by hospitals and sur...

    Authors: Ravi Maheswaran and Nick Morley

    Citation: BMC Cancer 2018 18:25

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  30. Content type: Research article

    Availability and affordability of anticancer medicines is a matter of great concern especially for low and middle income countries e.g., Pakistan. Prime focus of this study was to evaluate the availability of ...

    Authors: Muhammad Rehan Sarwar, Sadia Iftikhar and Anum Saqib

    Citation: BMC Cancer 2018 18:14

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  31. Content type: Study protocol

    Cancer survival comes at a price: pediatric cancer survivors bear a high risk for a wide range of cognitive difficulties. Therefore, interventions targeting these difficulties are required. The aim of the pres...

    Authors: Valentin Benzing, Noëmi Eggenberger, Janine Spitzhüttl, Valerie Siegwart, Manuela Pastore-Wapp, Claus Kiefer, Nedelina Slavova, Michael Grotzer, Theda Heinks, Mirko Schmidt, Achim Conzelmann, Maja Steinlin, Regula Everts and Kurt Leibundgut

    Citation: BMC Cancer 2018 18:18

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  32. Content type: Research article

    Head and neck cancer squamous cell carcinoma (HNSSC) patients report substantial rates of clinically significant depression and/or anxiety, with dysphagia being a predictor of distress and poorer quality of li...

    Authors: J. M. Patterson, M. Fay, C. Exley, E. McColl, M. Breckons and V. Deary

    Citation: BMC Cancer 2018 18:1

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  33. Content type: Research article

    Globally, cancer is one of the leading causes of mortality. High treatment cost, partly owing to higher prices of anti-cancer drugs, presents a significant burden on patients and healthcare systems. The aim of...

    Authors: Shahrzad Salmasi, Kah Seng Lee, Long Chiau Ming, Chin Fen Neoh, Mahmoud E. Elrggal, Zaheer-Ud- Din Babar, Tahir Mehmood Khan and Muhammad Abdul Hadi

    Citation: BMC Cancer 2017 17:903

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  34. Content type: Research article

    Use of dietary supplements among cancer survivors is common and controversial, but information on the amount of nutrients from supplements among cancer survivors is limited. We examined the amount of nutrients...

    Authors: Sihan Song, Jiyoung Youn, Yun Jung Lee, Minji Kang, Taisun Hyun, YoonJu Song and Jung Eun Lee

    Citation: BMC Cancer 2017 17:891

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  35. Content type: Research article

    In Denmark, national roll-out of a population-based, screening mammography program took place in 2007–2010. We report on outcome of the first four biennial invitation rounds.

    Authors: Elsebeth Lynge, Martin Bak, My von Euler-Chelpin, Niels Kroman, Anders Lernevall, Nikolaj Borg Mogensen, Walter Schwartz, Adam Jan Wronecki and Ilse Vejborg

    Citation: BMC Cancer 2017 17:897

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  36. Content type: Research article

    Case reports, retrospective analyses, and observational studies have linked the use of cisplatin to increased risk of second cancers, especially life-threatening secondary leukemia. We therefore performed a sy...

    Authors: Fei Liang, Sheng Zhang, Hongxi Xue and Qiang Chen

    Citation: BMC Cancer 2017 17:871

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  37. Content type: Research article

    Cervical cancer is the most common cancer in women living in Vientiane, Lao People’s Democratic Republic (PDR). This study examines cervical cytology using a liquid-based cytology (LBC) method and reports the ...

    Authors: Reika Takamatsu, Viengvansay Nabandith, Vatsana Pholsena, Phouthasone Mounthisone, Katsu Nakasone, Kentarou Ohtake and Naoki Yoshimi

    Citation: BMC Cancer 2017 17:872

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  38. Content type: Research article

    Low income and uninsured individuals often have lower adherence to cancer screening for breast, cervical and colorectal cancer. Health fairs are a common community outreach strategy used to provide cancer-rela...

    Authors: Cam Escoffery, Shuting Liang, Kirsten Rodgers, Regine Haardoerfer, Grace Hennessy, Kendra Gilbertson, Natalia I. Heredia, Leticia A. Gatus and Maria E. Fernandez

    Citation: BMC Cancer 2017 17:865

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  39. Content type: Research article

    Obesity is linked to poor disease outcomes in breast cancer patients. However, this link was mostly based on body weight or BMI rather than body-fat. The purpose of this study was to evaluate the relationship ...

    Authors: Li-Ni Liu, Yung-Chang Lin, Christine Miaskowski, Shin-Cheh Chen and Mei-Ling Chen

    Citation: BMC Cancer 2017 17:863

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  40. Content type: Research article

    Physician recommendations for colorectal cancer (CRC) screening have consistently been shown to be a strong predictor of screening. The aim of this study was to investigate perceptions of CRC screening modalit...

    Authors: Hye Young Shin, Mina Suh, Boyoung Park, Jae Kwan Jun and Kui Son Choi

    Citation: BMC Cancer 2017 17:860

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  41. Content type: Research article

    In a previous paper, we had assumed that the risk of screen-detected breast cancer mostly reflects inherent risk, and the risk of whether a breast cancer is interval versus screen-detected mostly reflects risk...

    Authors: Kavitha Krishnan, Laura Baglietto, Jennifer Stone, Catriona McLean, Melissa C. Southey, Dallas R. English, Graham G. Giles and John L. Hopper

    Citation: BMC Cancer 2017 17:859

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  42. Content type: Research article

    The prevalence of Hereditary Non-Polyposis Colorectal Cancer (HNPCC) is 2 to 5% in the Caucasian population. HNPCC is caused by genomic mutations in DNA mismatch repair genes (MMR), namely MLH1, MSH2, MSH6, PMS2,

    Authors: Jasmine Lee, Yin-Yi Xiao, Yan Yu Sun, Jasminka Balderacchi, Bradley Clark, Jatin Desani, Vivek Kumar, Angela Saverimuthu, Khin Than Win, Yiwu Huang and Yiqing Xu

    Citation: BMC Cancer 2017 17:843

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  43. Content type: Research article

    Evidence suggests that risk of colorectal and prostate cancer is increased among those with a family history of the same disease, particularly among first-degree relatives. However, the aggregation of colorect...

    Authors: Jennifer L. Beebe-Dimmer, Cecilia Yee, Electra Paskett, Ann G. Schwartz, Dorothy Lane, Nynikka R. A. Palmer, Cathryn H. Bock, Rami Nassir and Michael S. Simon

    Citation: BMC Cancer 2017 17:848

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  44. Content type: Study protocol

    In Chile, more than 500 women die every year from cervical cancer, and a majority of Chilean women are not up-to-date with their Papanicolau (Pap) test. Mobile health has great potential in many health areas, ...

    Authors: McKenzie C. Momany, Javiera Martinez-Gutierrez, Mauricio Soto, Daniel Capurro, Francis Ciampi, Beti Thompson and Klaus Puschel

    Citation: BMC Cancer 2017 17:847

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