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Epidemiology, prevention and public health

This section aims to consider publications which focus on all aspects of cancer epidemiology including risk factors for disease initiation and development, social determinants, environmental, behavioural, and occupational correlates, and the impact of health policies, practices and interventions on the community.

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  1. Previous studies conducted on the association between diabetes and the risk of endometrial cancer have reported controversial results that have raised a variety of questions about the association between diabe...

    Authors: Lotfolah Saed, Fatemeh Varse, Hamid Reza Baradaran, Yousef Moradi, Sorour Khateri, Emilie Friberg, Zaher Khazaei, Saeedeh Gharahjeh, Shahrzad Tehrani, Amir-Babak Sioofy-Khojine and Zahra Najmi

    Citation: BMC Cancer 2019 19:527

    Content type: Research article

    Published on:

  2. Population-based estimates of the long-term risk of loco-regional recurrence and distant metastases of breast cancer (BRC) patients are scant, as most published studies used hospital-based cohorts or participa...

    Authors: Bernd Holleczek, Christa Stegmaier, Julia C. Radosa, Erich-Franz Solomayer and Hermann Brenner

    Citation: BMC Cancer 2019 19:520

    Content type: Research article

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  4. Breast cancer screening mammography is widespread in industrialised countries within the framework of public health program or opportunist form. Only few data exist on the comparison of effectiveness between o...

    Authors: Sarah Peisl, Stefan Zimmermann, Bertrand Camey, Daniel Betticher and Christine Bouchardy

    Citation: BMC Cancer 2019 19:469

    Content type: Research article

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  5. We investigated the risk of thyroid disorders, namely hypothyroidism, thyrotoxicosis and thyroiditis, in head and neck cancer patients undergoing multimodal treatment.

    Authors: Chien-Liang Lin, Shang-Yin Wu, Wen-Tsung Huang, Yin-Hsun Feng, Ching-Yi Yiu, Wei-Fan Chiang, Sheng-Yow Ho and Sheng-Hsiang Lin

    Citation: BMC Cancer 2019 19:461

    Content type: Research article

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  7. Breast cancer is the most common female cancer in Brazil with an estimated 60 thousand new cases per year. Widespread use of mammography opportunistic screening has been observed in the last 20 years, includin...

    Authors: Diama Bhadra Vale, Cassio Cardoso Filho, Julia Yoriko Shinzato, Fernanda Servidoni Spreafico, Partha Basu and Luiz Carlos Zeferino

    Citation: BMC Cancer 2019 19:432

    Content type: Research article

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  8. Colorectal cancer (CRC) is globally one of the most common cancers. Although studies have found a significant prognostic impact of cancer location for right-sided colon cancers compared with those of the left-...

    Authors: Hiroko Nakagawa-Senda, Megumi Hori, Tomohiro Matsuda and Hidemi Ito

    Citation: BMC Cancer 2019 19:431

    Content type: Research article

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  11. The best strategy for surveillance testing in stage II and III colon cancer patients following curative treatment is unknown. Previous randomized controlled trials have suffered from design limitations and yie...

    Authors: Robert B. Hines, Md Jibanul Haque Jiban, Adrian V. Specogna, Priya Vishnubhotla, Eunkyung Lee and Shunpu Zhang

    Citation: BMC Cancer 2019 19:418

    Content type: Research article

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  12. In Ethiopia, the incidence of new cases of breast cancer is currently increasing resulting to high rates of morbidity and mortality. Breast cancer is by far the most common cancer accounting for more than one ...

    Authors: Biniyam Tefera Deressa, Nikola Cihoric, Eugenia Vlaskou Badra, Alexandros Tsikkinis and Daniel Rauch

    Citation: BMC Cancer 2019 19:393

    Content type: Research article

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  13. Effector CD8+ T cell activation and its cytotoxic function to eradicate tumor cells depend on the T cell recognition of tumor neoantigens, and are positively associated with improved survival in breast cancer. Tu...

    Authors: Lingeng Lu, Huatian Huang, Jing Zhou, Wenxue Ma, Sean Mackay and Zuoheng Wang

    Citation: BMC Cancer 2019 19:387

    Content type: Research article

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  14. Little is known about the pathway to diagnosis of lymphoma in Sub-Saharan Africa, despite the increased risk of lymphoma in people living with HIV (PLHIV). The challenges of diagnosis in this setting include d...

    Authors: Katherine Antel, Carly Levetan, Zainab Mohamed, Vernon J Louw, Jenna Oosthuizen, Gary Maartens and Estelle Verburgh

    Citation: BMC Cancer 2019 19:384

    Content type: Research article

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  15. The healthcare system (HCS) improved in Tibet Autonomous Region (TAR), China. The present study aimed to investigate whether these improvements might alter the clinicopathological characteristics of a Tibetan ...

    Authors: Yulan Zhao, Hanhuan Luo, Xintian Zhang, Tashi Bianba, Lin Li, Qian Wang, Lei Guo, Dian Wang, Yongge Ze and Shan Zheng

    Citation: BMC Cancer 2019 19:380

    Content type: Research article

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  16. Smoking is one of the well-established risk factors for gastric cancer incidence, yet whether men are more or equally susceptible to gastric cancer due to smoking compared with women is a matter of controversy...

    Authors: Wen-Ya Li, Yunan Han, Hui-Mian Xu, Zhen-Ning Wang, Ying-Ying Xu, Yong-Xi Song, Hao Xu, Song-Cheng Yin, Xing-Yu Liu and Zhi-Feng Miao

    Citation: BMC Cancer 2019 19:377

    Content type: Research article

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  17. Cervical Cancer is still a major public health challenge in low and middle-income countries. HPV testing has been an innovative approach, which was introduced in Argentina for women aged 30+ through the Jujuy ...

    Authors: Juan Gago, Melisa Paolino and Silvina Arrossi

    Citation: BMC Cancer 2019 19:367

    Content type: Research article

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  18. Phase I trials aim to identify the recommended dose for further development. Health-related quality of life (HRQoL) could be a complement to the usual National Cancer Institute Common Terminology Criteria for ...

    Authors: Frédéric Fiteni, Isabelle Le Ray, Ahmad Ousmen, Nicolas Isambert, Amélie Anota and Franck Bonnetain

    Citation: BMC Cancer 2019 19:361

    Content type: Research article

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  19. Salivary gland carcinoma ranks the sixth in head and neck cancers while it is relatively rare in its incidence. Epidemiological studies have been based mostly on institutional data, leading to selection bias i...

    Authors: Jin-Ye Fu, Chun-Xiao Wu, Shu-Kun Shen, Ying Zheng, Chen-Ping Zhang and Zhi-Yuan Zhang

    Citation: BMC Cancer 2019 19:350

    Content type: Research article

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  20. Extrahepatic cholangiocarcinoma (ECC) has become one of the most rapidly increasing malignancies in China during recent decades. The relationship between tobacco exposure and ECC epidemics is unclear; this stu...

    Authors: Lei Hou, Jingmei Jiang, Boqi Liu, Wei Han, Yanping Wu, Xiaonong Zou, Fang Xue, Yuanli Chen, Biao Zhang, Haiyu Pang, Yuyan Wang, Zixing Wang, Yaoda Hu and Junyao Li

    Citation: BMC Cancer 2019 19:348

    Content type: Research article

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  21. Incidence of renal dysfunction and risks of progression to end-stage renal disease (ESRD) were reported higher in upper urinary tract urothelial carcinoma (UTUC) than in renal cell carcinoma (RCC) patients aft...

    Authors: Sheng-Wen Niu, Peir-In Liang, Ming-Yen Lin, Shih-Meng Yeh, Yen-Yi Zhen, Yu-Han Chang, Pin-Chia Huang, Chi-Chi Hung, I-Ching Kuo, Hugo You-Hsien Lin, Mei-Chuan Kuo, Wei-Ming Li, Chun-Nung Huang, Wen-Jeng Wu, Li-Tzong Chen, Yi-Wen Chiu…

    Citation: BMC Cancer 2019 19:337

    Content type: Research article

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  22. Our aim was to determine the epidemiology and recent changes in the trends of non-functional pancreatic neuroendocrine tumours (NF-pNETs) at the population level. In addition, we explored the risk factors that...

    Authors: Junjun Wu, Chi Sun, Enliang Li, Jiakun Wang, Xianping He, Rongfa Yuan, Chenghao Yi, Wenjun Liao and Linquan Wu

    Citation: BMC Cancer 2019 19:334

    Content type: Research article

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  23. In France, a Pap test for cervical cancer screening is recommended every three years for all sexually active women aged 25 to 65 years. Modes of contraception (any or no contraception, with or without a visit to ...

    Authors: Stéphanie Mignot, Virginie Ringa, Solène Vigoureux, Marie Zins, Henri Panjo, Pierre-Jean Saulnier and Xavier Fritel

    Citation: BMC Cancer 2019 19:317

    Content type: Research article

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  24. Colorectal cancer (CRC) is the second cause of tumour mortality in Spain and Europe. To date, no studies have been conducted in Spain to evaluate the spatial and temporal distribution of the excess risk of dea...

    Authors: J. M. García-Torrecillas, M. C. Olvera-Porcel, M. Ferrer-Márquez, F. Rubio-Gil, M J. Sánchez and M. Rodríguez-Barranco

    Citation: BMC Cancer 2019 19:310

    Content type: Research article

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  25. Thyroid cancer is the most frequent endocrine neoplasia worldwide. Information from Andean countries is scarce. In Ecuador there is no reports available of the epidemiology of this type of cancer. The aim of t...

    Authors: Jorge Salazar-Vega, Esteban Ortiz-Prado, Paola Solis-Pazmino, Lenin Gómez-Barreno, Katherine Simbaña-Rivera, Aquiles R. Henriquez-Trujillo, Juan P. Brito, Theofilos Toulkeridis and Marco Coral-Almeida

    Citation: BMC Cancer 2019 19:294

    Content type: Research article

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  26. Human papillomavirus (HPV) vaccines are indicated for the prevention of cancers and genital warts caused by vaccine-covered HPV types. Although the standard regimen requires a two or three-dose vaccine series,...

    Authors: Yi Zeng, Anna-Barbara Moscicki, Vikrant V. Sahasrabuddhe, Francisco Garcia, Heide Woo, Chiu-Hsieh Hsu, Eva Szabo, Eileen Dimond, Susan Vanzzini, Angelica Mondragon, Valerie Butler, Hillary DeRose and H.-H. Sherry Chow

    Citation: BMC Cancer 2019 19:290

    Content type: Study protocol

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  27. Recently, the concept of “late presentation with viral hepatitis” was introduced to help quantify the proportion of patients missing timely diagnosis and treatment for viral hepatitis. The clinical implication...

    Authors: Dong Hyun Sinn, Danbee Kang, Minwoong Kang, Seung Woon Paik, Eliseo Guallar, Juhee Cho and Geum-Youn Gwak

    Citation: BMC Cancer 2019 19:286

    Content type: Research article

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  28. There is limited information on changes over time in carcinoid syndrome (CS) symptoms and quality of life (QoL). This study assessed change in CS symptoms and QoL in patients treated with somatostatin analogs ...

    Authors: Daniel M. Halperin, Lynn Huynh, Jennifer L. Beaumont, Beilei Cai, Rachel H. Bhak, Sahil Narkhede, Todor Totev, Mei S. Duh, Maureen P. Neary and David Cella

    Citation: BMC Cancer 2019 19:274

    Content type: Research article

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  29. Cardiovascular medications may be associated with cancer development, but little is known about their association with cancer recurrence. Medications such as statins and antihypertensives may be commonly used ...

    Authors: Erin J. A. Bowles, Onchee Yu, Rebecca Ziebell, Lu Chen, Denise M. Boudreau, Debra P. Ritzwoller, Rebecca A. Hubbard, Jennifer M. Boggs, Andrea N. Burnett-Hartman, Andrew Sterrett, Monica Fujii and Jessica Chubak

    Citation: BMC Cancer 2019 19:270

    Content type: Research article

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  30. Data from population-based cancer registries (PBCRs) are a useful resource for estimating the incidence of cancers. PBCR data is useful in the planning and implementation of cancer prevention and control strat...

    Authors: Yaw Ampem Amoako, Baffour Awuah, Rita Larsen-Reindorf, Fred Kwame Awittor, Gloria Kyem, Kwame Ofori-Boadu, Ernest Osei-Bonsu and Dennis Odai Laryea

    Citation: BMC Cancer 2019 19:267

    Content type: Research article

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  31. Although men carry a higher risk of hepatocellular carcinoma (HCC) than women, it is still controversial whether men also have a poorer postoperative prognosis. A retrospective study was conducted to evaluate ...

    Authors: Ming-Wei Lai, Yu-De Chu, Chih-Lang Lin, Rong-Nan Chien, Ta-Sen Yeh, Tai-Long Pan, Po-Yuan Ke, Kwang-Hui Lin and Chau-Ting Yeh

    Citation: BMC Cancer 2019 19:250

    Content type: Research article

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  32. Cancer indicators are essential information for cancer surveillance and cancer research strategy development. The Martinique Cancer Registry (MCR) is a population-based cancer Registry (PBCR) that has been rec...

    Authors: Clarisse Joachim, Jacqueline Veronique-Baudin, Stephen Ulric-Gervaise, Audrey Pomier, Aimée Pierre-Louis, Mylène Vestris, Jean-Luc Novella, Moustapha Drame, Jonathan Macni and Patrick Escarmant

    Citation: BMC Cancer 2019 19:239

    Content type: Research article

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  33. The purpose of the present study was to characterize the prevalence, associated factors, and to construct a nomogram for predicting bone metastasis (BM) with different histological types of lung cancer.

    Authors: Chao Zhang, Min Mao, Xu Guo, Ping Cui, Lianmin Zhang, Yao Xu, Lili Li, Xiuxin Han, Karl Peltzer, Shunbin Xiong, Vladimir P. Baklaushev, Xin Wang and Guowen Wang

    Citation: BMC Cancer 2019 19:238

    Content type: Research article

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  34. Breast cancer is the most common cancer in women worldwide, with a great diversity in outcomes among individual patients. The ability to accurately predict a breast cancer outcome is important to patients, phy...

    Authors: Minh Tung Phung, Sandar Tin Tin and J. Mark Elwood

    Citation: BMC Cancer 2019 19:230

    Content type: Research article

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  35. Despite strong evidence of benefit, breast cancer risk assessment and chemoprevention are underutilized by primary care physicians. This study evaluates the impact of an educational program on knowledge and ut...

    Authors: Siddhartha Yadav, Sarah Hartkop, Paola Yumpo Cardenas, Rand Ladkany, Alexandra Halalau, Sandor Shoichet, Michael Maddens and Dana Zakalik

    Citation: BMC Cancer 2019 19:228

    Content type: Research article

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  37. The gastric cancer incidence rate differs widely across geographical areas. In Italy, in the province of Cremona the incidence is high, compared to the national situation. For this reason a specialized populat...

    Authors: B. M. Donida, G. Tomasello, M. Ghidini, F. Buffoli, M. Grassi, W. Liguigli, G. Maglietta, L. Pergola, M. Ratti, G. Sabadini, L. Toppo, M. Ungari and R. Passalacqua

    Citation: BMC Cancer 2019 19:212

    Content type: Research article

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  38. Recurrence is not explicitly documented in cancer registry data that are widely used for research. Patterns of events after initial treatment such as oncology visits, re-operation, and receipt of subsequent ch...

    Authors: Yuan Xu, Shiying Kong, Winson Y. Cheung, Antoine Bouchard-Fortier, Joseph C. Dort, Hude Quan, Elizabeth M. Buie, Geoff McKinnon and May Lynn Quan

    Citation: BMC Cancer 2019 19:210

    Content type: Research article

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  39. The length of interval between successive childbirths (birth interval) might influence the incidence of breast cancer, either by stimulating or by inhibiting the factors that are responsible for the initiation...

    Authors: Sushmita Katuwal, Juha S. Tapanainen, Eero Pukkala and Antti Kauppila

    Citation: BMC Cancer 2019 19:199

    Content type: Research article

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  40. Philadelphia (Ph) chromosome-negative myeloproliferative neoplasms (MPNs) are a heterogeneous group of hematopoietic stem cell clonal diseases. Most patients with MPN are asymptomatic at diagnosis although som...

    Authors: Tarinee Rungjirajittranon, Weerapat Owattanapanich, Patompong Ungprasert, Noppadol Siritanaratkul and Theera Ruchutrakool

    Citation: BMC Cancer 2019 19:184

    Content type: Research article

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  41. Although rare cancers account for 27% of cancer diagnoses in the US, there is insufficient research on survivorship issues in these patients. An important issue cancer survivors face is an elevated risk of bei...

    Authors: Dianne M. Finkelstein, Nora K. Horick, Ritesh Ramchandani, Kristina L. Boyd, Huma Q. Rana and Brittany L. Bychkovsky

    Citation: BMC Cancer 2019 19:166

    Content type: Research article

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  42. The association of ABO blood groups with gastric cancer risk was proposed decades ago, but the results have been inconsistent.

    Authors: Yingying Mao, Wenjun Yang, Qi Qi, Fei Yu, Tianpei Wang, Hongfei Zhang, Juncheng Dai, Hongxia Ma, Zhibin Hu, Hongbing Shen, Gang Li and Guangfu Jin

    Citation: BMC Cancer 2019 19:164

    Content type: Research article

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  43. The aim of this study was to evaluate the prevalence of some gynecological cancer risk factors in a population of female relatives of cancer patients in Hacettepe University Oncology Hospital. Additionally, wh...

    Authors: Nooria Atta, Saadettin Kilickap, Deniz Yuce and Mutlu Hayran

    Citation: BMC Cancer 2019 19:154

    Content type: Research article

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  44. Chemotherapy-induced thrombocytopenia (CIT) is a potentially serious complication that can lead to chemotherapy dose delays, dose reductions, or discontinuation, and increases the risk of serious bleeding even...

    Authors: Derek Weycker, Mark Hatfield, Aaron Grossman, Ahuva Hanau, Alex Lonshteyn, Anjali Sharma and David Chandler

    Citation: BMC Cancer 2019 19:151

    Content type: Research article

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  46. The brain is a common site for metastasis in non-small-cell lung cancer (NSCLC). This study was designed to evaluate the relationship between the mutational of the epidermal growth factor receptor (EGFR) and o...

    Authors: Wen-Ya Li, Ting-Ting Zhao, Hui-Mian Xu, Zhen-Ning Wang, Ying-Ying Xu, Yunan Han, Yong-Xi Song, Jian-Hua Wu, Hao Xu, Song-Cheng Yin, Xing-Yu Liu and Zhi-Feng Miao

    Citation: BMC Cancer 2019 19:145

    Content type: Research article

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  47. Evidence from clinical trials suggests that the addition of bevacizumab to chemotherapy in the first-line treatment of patients with HER2-negative metastatic breast cancer improves progression-free survival (P...

    Authors: Audrey Petitjean, Jayne Smith-Palmer, William Valentine, Bertrand Tehard and Stephané Roze

    Citation: BMC Cancer 2019 19:140

    Content type: Research article

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  48. Intracranial and intraspinal tumours are the most numerous solid tumours in children. Some recently defined subtypes are relatively frequent in childhood. Many cancer registries routinely ascertain CNS tumours...

    Authors: Charles A. Stiller, Anita M. Bayne, Aruna Chakrabarty, Tom Kenny and Paul Chumas

    Citation: BMC Cancer 2019 19:139

    Content type: Research article

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  49. Considering the lack of efficient breast cancer prediction models suitable for general population screening in China. We aimed to develop a risk prediction model to identify high-risk populations, to help with...

    Authors: Lu Wang, Liyuan Liu, Zhen Lou, Lijie Ding, Hui Guan, Fei Wang, Lixiang Yu, Yujuan Xiang, Fei Zhou, Fuzhong Xue and Zhigang Yu

    Citation: BMC Cancer 2019 19:128

    Content type: Research article

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  50. The prognostic value of Ki-67 expression in colorectal cancer patients was controversial. Therefore, this meta analysis was conducted to ascertain the prognostic value of Ki-67 expression in colorectal cancer ...

    Authors: Zhao-Wen Luo, Ming-Gu Zhu, Zhi-Qiao Zhang, Feng-Jun Ye, Wen-Heng Huang and Xue-Zhang Luo

    Citation: BMC Cancer 2019 19:123

    Content type: Research article

    Published on:

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