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Epidemiology, prevention and public health

Section edited by Manami Inoue

This section aims to consider publications which focus on all aspects of cancer epidemiology including risk factors for disease initiation and development, social determinants, environmental, behavioural, and occupational correlates, and the impact of health policies, practices and interventions on the community.

Page 3 of 20

  1. Content type: Research article

    Thyroid cancer is the most common malignant disease of the endocrine system. Previous studies indicate a rapid increase in the incidence of thyroid cancer in recent decades, and this increase has aroused the g...

    Authors: Lingbin Du, Youqing Wang, Xiaohui Sun, Huizhang Li, Xinwei Geng, Minghua Ge and Yimin Zhu

    Citation: BMC Cancer 2018 18:291

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  2. Content type: Research article

    Epidemiological studies have clarified the potential associations between regular aspirin use and cancers. However, it remains controversial on whether aspirin use decreases the risk of cancers risks. Therefor...

    Authors: Yan Qiao, Tingting Yang, Yong Gan, Wenzhen Li, Chao Wang, Yanhong Gong and Zuxun Lu

    Citation: BMC Cancer 2018 18:288

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  3. Content type: Research article

    A number of studies have investigated the association between androgenic alopecia (AGA) and cancer risk, but they have yielded inconsistent results. Therefore, this study was conducted to explore this controve...

    Authors: Weijun Liang, Liuying Song, Zheng Peng, Yan Zou and Shengming Dai

    Citation: BMC Cancer 2018 18:279

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  4. Content type: Research article

    Reproductive factors are well known risk factors for breast cancer; however, little is known about how genetic variants in hormonal pathways interact with that relationship.

    Authors: Trinidad Dierssen-Sotos, Camilo Palazuelos-Calderón, José-Juan Jiménez-Moleón, Nuria Aragonés, Jone M. Altzibar, Gemma Castaño-Vinyals, Vicente Martín-Sanchez, Inés Gómez-Acebo, Marcela Guevara, Adonina Tardón, Beatriz Pérez-Gómez, Pilar Amiano, Victor Moreno, Antonio J. Molina, Jéssica Alonso-Molero, Conchi Moreno-Iribas…

    Citation: BMC Cancer 2018 18:280

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  5. Content type: Research article

    Cervical cancer screening participation remains insufficient in most countries. Our aim was to evaluate whether offering a HPV self-sampling kit, either mailed directly to the woman’s home or using timely opt-...

    Authors: Mette Tranberg, Bodil Hammer Bech, Jan Blaakær, Jørgen Skov Jensen, Hans Svanholm and Berit Andersen

    Citation: BMC Cancer 2018 18:273

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  8. Content type: Research article

    There is no international consensus up to which age women with a diagnosis of triple-negative breast cancer (TNBC) and no family history of breast or ovarian cancer should be offered genetic testing for germline

    Authors: Christoph Engel, Kerstin Rhiem, Eric Hahnen, Sibylle Loibl, Karsten E. Weber, Sabine Seiler, Silke Zachariae, Jan Hauke, Barbara Wappenschmidt, Anke Waha, Britta Blümcke, Marion Kiechle, Alfons Meindl, Dieter Niederacher, Claus R. Bartram, Dorothee Speiser…

    Citation: BMC Cancer 2018 18:265

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  9. Content type: Research article

    Cancer screening awareness and participation may be lower in low- and middle-income countries that lack established national screening programmes compared with those that do. We evaluated potential determinant...

    Authors: Sumadi L. Anwar, Gindo Tampubolon, Mieke Van Hemelrijck, Susanna H. Hutajulu, Johnathan Watkins and Wahyu Wulaningsih

    Citation: BMC Cancer 2018 18:208

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  11. Content type: Research article

    Between 2003 and 2010 digital mammography (DM) gradually replaced screen-film mammography (SFM) in the Dutch breast cancer screening programme (BCSP). Previous studies showed increases in detection rate (DR) a...

    Authors: Valérie D. V. Sankatsing, Jacques Fracheboud, Linda de Munck, Mireille J. M. Broeders, Nicolien T. van Ravesteyn, Eveline A. M. Heijnsdijk, André L. M. Verbeek, Johannes D. M. Otten, Ruud M. Pijnappel, Sabine Siesling and Harry J. de Koning

    Citation: BMC Cancer 2018 18:256

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  12. Content type: Research article

    Identifying female carriers of BRCA1 and BRCA2 mutations is imperative for prevention of ovarian cancer and breast cancer. There are five major histologic subtypes of ovarian cancer and high grade serous cancer (...

    Authors: Gillian E. Hanley, Jessica N. McAlpine, Dianne Miller, David Huntsman, Kasmintan A. Schrader, C. Blake Gilks and Gillian Mitchell

    Citation: BMC Cancer 2018 18:254

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  14. Content type: Research article

    Carers looking after someone with cancer often experience negative impacts on their own health. M-health interventions have been designed to provide information and support to patients and their carers. Howeve...

    Authors: Natalie Heynsbergh, Leila Heckel, Mari Botti and Patricia M. Livingston

    Citation: BMC Cancer 2018 18:244

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  15. Content type: Research article

    In recent years management practices in relation to low-risk papillary microcarcinoma (PMC) have been evolving with increased awareness of the potential overdiagnosis and overtreatment of PMCs, and guidelines ...

    Authors: Brooke Nickel, Juan P. Brito, Ray Moynihan, Alexandra Barratt, Susan Jordan and Kirsten McCaffery

    Citation: BMC Cancer 2018 18:242

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  16. Content type: Research article

    Consumption of very hot (> 65 °C) beverages is probably associated with increased risk of oesophageal cancer. First associations were reported for yerba mate and it was initially believed that high content of ...

    Authors: Alex O. Okaru, Anke Rullmann, Adriana Farah, Elvira Gonzalez de Mejia, Mariana C. Stern and Dirk W. Lachenmeier

    Citation: BMC Cancer 2018 18:236

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  18. Content type: Research article

    The centralisation of specialist cancer surgical services across London Cancer and Greater Manchester Cancer, England, may significantly change how patients experience care. These centres are changing specialist ...

    Authors: Mariya Melnychuk, Cecilia Vindrola-Padros, Michael Aitchison, Caroline S. Clarke, Naomi J. Fulop, Claire Levermore, Satish B. Maddineni, Caroline M. Moore, Muntzer M. Mughal, Catherine Perry, Kathy Pritchard-Jones, Angus I. G. Ramsay, David Shackley, Jonathan Vickers and Stephen Morris

    Citation: BMC Cancer 2018 18:226

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  19. Content type: Research article

    Gastroenterology Departments at hospitals within Australia receive thousands of General Practitioner (GP)-referral letters for gastrointestinal investigations every month. Many of these requests are for colono...

    Authors: Anton R. Lord, Lisa A. Simms, Allison Brown, Katherine Hanigan, Krupa Krishnaprasad, Belinda Schouten, Anthony R. Croft, Mark N. Appleyard and Graham L. Radford-Smith

    Citation: BMC Cancer 2018 18:229

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  20. Content type: Research article

    The insulin receptor (INSR) and the insulin growth factor 1 receptor (IGF1R) play important roles in the etiology of both diabetes mellitus and breast cancer. We aimed to evaluate the expression of hormone and...

    Authors: Heleen K. Bronsveld, Marie L. De Bruin, Jelle Wesseling, Joyce Sanders, Ingrid Hofland, Vibeke Jensen, Marloes T. Bazelier, Bas ter Braak, Anthonius de Boer, Peter Vestergaard and Marjanka K. Schmidt

    Citation: BMC Cancer 2018 18:224

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  21. Content type: Research article

    Aspirin has been proposed as a novel adjuvant agent in colorectal cancer (CRC). Six observational studies have reported CRC-specific survival outcomes in patients using aspirin after CRC diagnosis but the resu...

    Authors: Ronan T. Gray, Helen G. Coleman, Carmel Hughes, Liam J. Murray and Chris R. Cardwell

    Citation: BMC Cancer 2018 18:228

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  22. Content type: Research article

    Obesity has been proposed as a potential protective factor against lung cancer. We examined the association between BMI and lung cancer risk in a pooled analysis based on nested case-control studies from four ...

    Authors: Harinakshi Sanikini, Jian-Min Yuan, Lesley M. Butler, Woon-Puay Koh, Yu-Tang Gao, Annika Steffen, Mattias Johansson, Paolo Vineis, Gary E. Goodman, Matt J. Barnett, Rayjean J. Hung, Chu Chen and Isabelle Stücker

    Citation: BMC Cancer 2018 18:220

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  23. Content type: Research article

    Aberrant crypt foci (ACF) are commonly considered the early pre-cancerous lesions that can progress to colorectal cancer (CRC). The available literature data reveal that age, dietary factors and lifestyle can ...

    Authors: Marek Kowalczyk, Marcin Orłowski, Piotr Siermontowski, Dariusz Mucha, Krzysztof Zinkiewicz, Waldemar Kurpiewski, Ewa Zieliński, Iwona Kowalczyk and Agnieszka Pedrycz

    Citation: BMC Cancer 2018 18:213

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  24. Content type: Research article

    Mammography screening is used to detect breast cancer at an early treatable stage, reducing breast cancer mortality. Traditionally, breast cancer has been seen as a disease with only progressive lesions, and h...

    Authors: Åsbjørn Schumacher Westvik, Harald Weedon-Fekjær, Jan Mæhlen and Knut Liestøl

    Citation: BMC Cancer 2018 18:209

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  25. Content type: Research article

    Improvements in detection and treatment of prostate cancer (PCa) translate into more men living with PCa, who are therefore potentially at risk of a secondly diagnosed primary tumour (SDPTs). Little is known a...

    Authors: Cecilia Bosco, Hans Garmo, Niklas Hammar, Göran Walldius, Ingmar Jungner, Håkan Malmström, Lars Holmberg and Mieke Van Hemelrijck

    Citation: BMC Cancer 2018 18:205

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  26. Content type: Research article

    Physical activity has been implicated as a risk factor in the development of testicular cancer (TC), but the relationship remains controversial. This systematic review pooled available evidence regarding this ...

    Authors: Stephanie Huang, Virginia Signal, Diana Sarfati, Caroline Shaw, James Stanley, Katherine McGlynn and Jason Gurney

    Citation: BMC Cancer 2018 18:189

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  27. Content type: Research article

    Subjects with elevated Epstein-Barr virus (EBV) immunoglobulin A (IgA) titers have a higher risk of developing nasopharyngeal carcinoma (NPC), indicating that reactivation of EBV in the local mucosa might be i...

    Authors: Yufeng Chen, Yifei Xu, Weilin Zhao, Xue Xiao, Xiaoying Zhou, Longde Lin, Tingting Huang, Jian Liao, Yancheng Li, Xiaoyun Zeng, Guangwu Huang, Weimin Ye and Zhe Zhang

    Citation: BMC Cancer 2018 18:190

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  28. Content type: Research article

    Chronic inflammatory conditions are associated with higher tumor incidence through epigenetic and genetic alterations. Here, we focused on an association between an inflammation marker, C-reactive-protein (CRP...

    Authors: Masanori Nojima, Motoki Iwasaki, Yoshio Kasuga, Shiro Yokoyama, Hiroshi Onuma, Hideki Nishimura, Ritsu Kusama, Teruhiko Yoshida and Shoichiro Tsugane

    Citation: BMC Cancer 2018 18:184

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  29. Content type: Research article

    Nijmegen breakage syndrome 1 (NBS1), as a key protein in the DNA double-strand breaks (DSBs) repair pathway, plays an important role in maintaining genomic stability. Although single nucleotide polymorphisms (SNP...

    Authors: Xinmei Hu, Juan Liao, Huiliu Zhao, Feng Chen, Xuefeng Zhu, Jiangheng Li and Qingqing Nong

    Citation: BMC Cancer 2018 18:175

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  30. Content type: Research article

    In addition to tumor characteristics and lifestyle factors, cancer relapses are often related to the risk of death but have not been jointly studied. We investigate the prognostic factors of recurrent events a...

    Authors: Alexandre Lafourcade, Mathilde His, Laura Baglietto, Marie-Christine Boutron-Ruault, Laure Dossus and Virginie Rondeau

    Citation: BMC Cancer 2018 18:171

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  31. Content type: Research article

    Estimates of cancer prevalence are widely based on limited duration, often including patients living after a cancer diagnosis made in the previous 5 years and less frequently on complete prevalence (i.e., incl...

    Authors: Stefano Guzzinati, Saverio Virdone, Roberta De Angelis, Chiara Panato, Carlotta Buzzoni, Riccardo Capocaccia, Silvia Francisci, Anna Gigli, Manuel Zorzi, Giovanna Tagliabue, Diego Serraino, Fabio Falcini, Claudia Casella, Antonio Giampiero Russo, Fabrizio Stracci, Bianca Caruso…

    Citation: BMC Cancer 2018 18:169

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  32. Content type: Research article

    Inconsistent associations between smoking status and prostate cancer (PC) could be due to exposure assessment error. Reconstructing smoking behaviors over the life course could reduce exposure assessment error.

    Authors: Evelyn Jiménez-Mendoza, Ruth A. Vázquez-Salas, Tonatiuh Barrientos-Gutierrez, Luz Myriam Reynales-Shigematsu, Isaac Roberto Labra-Salgado, Hugo A. Manzanilla-García and Luisa E. Torres-Sánchez

    Citation: BMC Cancer 2018 18:160

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  33. Content type: Research article

    An increasing incidence of thyroid cancer is observed in many developed countries. Increasing incidence may also reflect better reporting or increased diagnostic scrutiny. We conducted this study to examine tr...

    Authors: Umesh Jayarajah, Ashan Fernando, Saumyakala Prabashani, Eshani A. Fernando and Sanjeewa A. Seneviratne

    Citation: BMC Cancer 2018 18:163

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  34. Content type: Research article

    The incidence and incidence trends of breast cancer according to molecular subtype are unknown at a population level in France. The registry data enables this study and may give this information, that is cruci...

    Authors: Marion Cortet, Aurélie Bertaut, Florence Molinié, Simona Bara, Françoise Beltjens, Charles Coutant and Patrick Arveux

    Citation: BMC Cancer 2018 18:161

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  35. Content type: Research article

    The present study (1) examined patient satisfaction with care over the first year following the diagnosis of advanced breast cancer and (2) tested if unmet health system and information needs, physical symptom...

    Authors: Wendy W. T. Lam, Ava Kwong, Dacita Suen, Janice Tsang, Inda Soong, Tze Kok Yau, Winnie Yeo, Joyce Suen, Wing Ming Ho, Ka Yan Wong, Wing Kin Sze, Alice W. Y. Ng and Richard Fielding

    Citation: BMC Cancer 2018 18:162

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  36. Content type: Research article

    The rs2282679 A>C polymorphism in the vitamin D binding protein gene is associated with lower circulating levels of vitamin D. We investigated associations of this SNP with colorectal cancer (CRC) risk and sur...

    Authors: Yun Zhu, Peizhong Peter Wang, Guangju Zhai, Bharati Bapat, Sevtap Savas, Jennifer R. Woodrow, Peter T. Campbell, Yuming Li, Ning Yang, Xin Zhou, Elizabeth Dicks, John R. Mclaughlin and Patrick S. Parfrey

    Citation: BMC Cancer 2018 18:155

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  38. Content type: Research article

    We evaluated treatment decisions and outcomes in a cohort of predominately Caucasian patients with EGFR mutation-positive (EGFR Mut+) non-small-cell lung cancer (NSCLC).

    Authors: Wolfgang Schuette, Peter Schirmacher, Wilfried E. E. Eberhardt, Manfred Dietel, Ute Zirrgiebel, Lars Muehlenhoff and Michael Thomas

    Citation: BMC Cancer 2018 18:135

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  39. Content type: Research article

    It has been suggested that distal gastric carcinoma (GC) in younger patients has a more aggressive outcome than in older patients, however this is a controversial issue. The aim of this study was to compare cl...

    Authors: Manuel B. Braga-Neto, Jessica Gomes Carneiro, Alzira M. de Castro Barbosa, Igor S. Silva, Danielle C. Maia, Felipe S. Maciel, Rafael Jorge Alves de Alcântara, Paulo Roberto L. Vasconscelos and Lucia L. B. C. Braga

    Citation: BMC Cancer 2018 18:131

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  40. Content type: Research article

    Quality indicators for the Brazilian cervical cancer screening programme can provide a perspective on its effectiveness in Brazilian macro-regions and states. The aim of this study was to perform a trend analy...

    Authors: Ricardo Filipe Alves Costa, Adhemar Longatto-Filho, Fabiana de Lima Vazquez, Céline Pinheiro, Luiz Carlos Zeferino and José Humberto Tavares Guerreiro Fregnani

    Citation: BMC Cancer 2018 18:126

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  41. Content type: Research article

    Patients with primary brain tumors are reported to have an elevated level of distress prevalence, due to the functional sequelae and the unfavorable prognosis, but the estimated prevalence of this disorder var...

    Authors: Fangkun Liu, Jing Huang, Liyang Zhang, Fan Fan, Jindong Chen, Kun Xia and Zhixiong Liu

    Citation: BMC Cancer 2018 18:124

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  42. Content type: Research article

    Lung cancer is the leading cause of cancer-related mortality in Utah despite having the nation’s lowest smoking rate. Radon exposure and differences in lung cancer incidence between nonmetropolitan and metropo...

    Authors: Judy Y. Ou, Brynn Fowler, Qian Ding, Anne C. Kirchhoff, Lisa Pappas, Kenneth Boucher, Wallace Akerley, Yelena Wu, Kimberly Kaphingst, Garrett Harding and Deanna Kepka

    Citation: BMC Cancer 2018 18:115

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  43. Content type: Research article

    Breast cancer survivors are at high risk for fracture due to cancer treatment-induced bone loss, however, data is scarce regarding the scope of this problem from an epidemiologic and health services perspectiv...

    Authors: Evelyn Hsieh, Qin Wang, Renzhi Zhang, Xin Niu, Weibo Xia, Liana Fraenkel, Karl L. Insogna, Jing Li, Jennifer S. Smith, Chunwu Zhou, You-lin Qiao and Pin Zhang

    Citation: BMC Cancer 2018 18:104

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  44. Content type: Research article

    Surveys indicate quite high prevalence of cancer worry in the general population, but little is known about what it is about cancer that worries people. A better understanding of the origins of cancer worry ma...

    Authors: Philippa J. Murphy, Laura A. V. Marlow, Jo Waller and Charlotte Vrinten

    Citation: BMC Cancer 2018 18:86

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  45. Content type: Research article

    This study explores the effectiveness and cost-effectiveness of surveillance after breast cancer treatment provided in a hospital-setting versus surveillance embedded in the community-based National Breast Can...

    Authors: Kelly M. de Ligt, Annemieke Witteveen, Sabine Siesling and Lotte M. G. Steuten

    Citation: BMC Cancer 2018 18:96

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  46. Content type: Research article

    Deaf people represent 0.1% of the French population and their access to public health campaigns is limited due to their frequent illiteracy and the infrequent use of sign language in campaigns. There is also a...

    Authors: Vladimir Druel, Hélène Hayet, Laetitia Esman, Marie Clavel and Marie-Eve Rougé Bugat

    Citation: BMC Cancer 2018 18:93

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  47. Content type: Research article

    There is ongoing debate about the harms and benefits of a national prostate cancer screening programme. Several model-based cost-effectiveness analyses have been developed to determine whether the benefits of ...

    Authors: Sabina Sanghera, Joanna Coast, Richard M. Martin, Jenny L. Donovan and Syed Mohiuddin

    Citation: BMC Cancer 2018 18:84

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  48. Content type: Research article

    We evaluated the incidence and spectrum of pathogenic and likely pathogenic variants of cancer susceptibility genes in BRCA1/2 mutation-negative Korean patients with a high risk for hereditary breast cancer using...

    Authors: Ji Soo Park, Seung-Tae Lee, Eun Ji Nam, Jung Woo Han, Jung-Yun Lee, Jieun Kim, Tae Il Kim and Hyung Seok Park

    Citation: BMC Cancer 2018 18:83

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  49. Content type: Research article

    Obesity has been reported as an adverse prognostic factor in breast cancer, but inconsistently, and under-treatment with chemotherapy may occur. We provide the first assessment of obesity and breast cancer out...

    Authors: J. Mark Elwood, Sandar Tin Tin, Marion Kuper-Hommel, Ross Lawrenson and Ian Campbell

    Citation: BMC Cancer 2018 18:76

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  50. Content type: Research article

    Physical activity is consistently associated with a reduced risk of colorectal cancer in epidemiologic studies. This association among higher risk subgroups, such as those with a first-degree family history of...

    Authors: Eileen Shaw, Megan S. Farris, Chelsea R. Stone, Jeroen W. G. Derksen, Rhys Johnson, Robert J. Hilsden, Christine M. Friedenreich and Darren R. Brenner

    Citation: BMC Cancer 2018 18:71

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