Skip to main content


Epidemiology, prevention and public health

This section aims to consider publications which focus on all aspects of cancer epidemiology including risk factors for disease initiation and development, social determinants, environmental, behavioural, and occupational correlates, and the impact of health policies, practices and interventions on the community.

Page 3 of 23

  1. Content type: Research article

    Male Breast Cancer (MBC) is rare, which makes its understanding and treatment be extrapolated from what is known about the occurrence in women, with few epidemiological studies. Therefore, the aim of the prese...

    Authors: Jean Henri Maselli-Schoueri, Fernando Alves Affonso-Kaufman, Claudia Vaz de Melo Sette, Francisco Winter dos Santos Figueiredo and Fernando Adami

    Citation: BMC Cancer 2019 19:23

    Published on:

  2. Content type: Research article

    Nutrition labeling has been found to affect the amount and type of food intake, with certain groups in the population, such as cancer survivors, being more aware of this information. A higher awareness of nutr...

    Authors: Ji Sung Yoo, Kyu-Tae Han, Seung Hyun Chung and Eun-Cheol Park

    Citation: BMC Cancer 2019 19:16

    Published on:

  3. Content type: Research article

    Metachronous cancer in patients with head and neck cancer (HNC) is common and is associated with a poor prognosis. We aimed to evaluate the incidence of metachronous cancer at different sites according to age ...

    Authors: Taro Iwatsubo, Ryu Ishihara, Toshitaka Morishima, Akira Maekawa, Kentaro Nakagawa, Masamichi Arao, Masayasu Ohmori, Hiroyoshi Iwagami, Kenshi Matsuno, Shuntaro Inoue, Hiroko Nakahira, Noriko Matsuura, Satoki Shichijo, Takashi Kanesaka, Sachiko Yamamoto, Yoji Takeuchi…

    Citation: BMC Cancer 2019 19:3

    Published on:

  4. Content type: Research article

    Physical fitness and psychosocial function is often reduced in children during or shortly after cancer treatment. This study evaluates the effect of a combined physical exercise and psychosocial intervention o...

    Authors: Katja I. Braam, Elisabeth M. van Dijk-Lokkart, Gertjan J. L. Kaspers, Tim Takken, Jaap Huisman, Laurien M. Buffart, Marc B. Bierings, Johannes H. M. Merks, Marry M. van den Heuvel-Eibrink, Margreet A. Veening and Eline van Dulmen-den Broeder

    Citation: BMC Cancer 2018 18:1289

    Published on:

  5. Content type: Research article

    The prevalence and distribution of histologically diagnosed breast disease are not well documented in low income countries, Uganda inclusive. Although the greater majority of breast lesions globally are benign...

    Authors: Salvatore Ssemmanda, Eric Katagirya, Phiona Bukirwa, David Alele, Robert Lukande and Samuel Kalungi

    Citation: BMC Cancer 2018 18:1285

    Published on:

  6. Content type: Research article

    Few epidemiologic findings are as well established as the association between smoking and lung cancer. It is therefore somewhat surprising that there is not yet a clear consensus about the exposure-response re...

    Authors: T. Remen, J. Pintos, M. Abrahamowicz and J. Siemiatycki

    Citation: BMC Cancer 2018 18:1275

    Published on:

  7. Content type: Research article

    Kaposi’s sarcoma (KS) is a multifocal angioproliferative tumor involving blood and lymphatic vessels, caused by Human Herpes Virus-8 (HHV-8). KS is an important AIDS-defining tumor with high prevalence in Sub-...

    Authors: George P. Semango, Renard M. Charles, Consolata I. Swai, Alex Mremi, Patrick Amsi, Tolbert Sonda, Elichilia R. Shao, Daudi R. Mavura, Leo A. B. Joosten, Elingarami Sauli and Mramba Nyindo

    Citation: BMC Cancer 2018 18:1258

    Published on:

  8. Content type: Research article

    Diabetes mellitus (DM) is associated with poorer outcomes in some cancers. Its effect on ovarian cancer is less clear. We consider the effect of DM on overall survival (OS) and progression free survival (PFS) ...

    Authors: Setareh Akhavan, Akram Ghahghaei-Nezamabadi, Mitra Modaresgilani, Azam Sadat Mousavi, Mahdi Sepidarkish, Afsaneh Tehranian and Elahe Rezayof

    Citation: BMC Cancer 2018 18:1246

    Published on:

  9. Content type: Research article

    Myeloid-derived suppressor cells (MDSCs) is a heterogeneous population of immature myeloid cells, inhibiting both the innate and adaptive immunity. Recent studies validated that MDSCs caused immune suppression...

    Authors: Lisha Ai, Shidai Mu, Yadan Wang, Huafang Wang, Li Cai, Wenzhu Li and Yu Hu

    Citation: BMC Cancer 2018 18:1220

    Published on:

  10. Content type: Research article

    Colorectal cancer (CRC) remains the second most common cancer in women worldwide. Physical activity (PA) has been associated with reduced risk of CRC; however, this has been demonstrated more consistently in m...

    Authors: Sunday Oluwafemi Oyeyemi, Tonje Braaten, Idlir Licaj, Eiliv Lund and Kristin Benjaminsen Borch

    Citation: BMC Cancer 2018 18:1216

    Published on:

  11. Content type: Research article

    There are racial/ethnic disparities in breast cancer mortality may be attributed to differences in receipt of adjuvant cancer treatment. Our purpose was to determine whether the mortality disparities could be ...

    Authors: Albert J. Farias, Wen-Hsing Wu and Xianglin L. Du

    Citation: BMC Cancer 2018 18:1214

    Published on:

  12. Content type: Study protocol

    Epidemiological studies and cardiovascular prevention trials have shown that low-dose aspirin can reduce colorectal cancer (CRC) incidence and mortality, including inhibition of distant metastases. Metformin h...

    Authors: Marilena Petrera, Laura Paleari, Matteo Clavarezza, Matteo Puntoni, Silvia Caviglia, Irene Maria Briata, Massimo Oppezzi, Eva Mihajlovic Mislej, Borut Stabuc, Michael Gnant, Thomas Bachleitner-Hofmann, Wilfried Roth, Dominique Scherer, Walter-E. Haefeli, Cornelia M. Ulrich and Andrea DeCensi

    Citation: BMC Cancer 2018 18:1210

    Published on:

  13. Content type: Research article

    Timely assessment of cancer risk from current radiation exposure among medical radiation workers can contribute to the development of strategies to prevent excessive occupational radiation exposure. The purpos...

    Authors: Won Jin Lee, Yeongchull Choi, Seulki Ko, Eun Shil Cha, Jaeyoung Kim, Young Min Kim, Kyoung Ae Kong, Songwon Seo, Ye Jin Bang and Yae Won Ha

    Citation: BMC Cancer 2018 18:1206

    Published on:

  14. Content type: Research article

    Mammographic density is a known risk factor for breast cancer, but the underlying pathologic characteristics are not well understood. The current analysis investigated the expression of several markers of inte...

    Authors: Gertraud Maskarinec, Dan Ju, Jaimie Fong, David Horio, Owen Chan, Lenora W. M. Loo and Brenda Y. Hernandez

    Citation: BMC Cancer 2018 18:1191

    Published on:

  15. Content type: Research article

    Previous epidemiological studies aimed at describing characteristics of breast (BC) and ovarian cancer (OC) patients tend to examine Hispanic populations using a mix of individuals that come from ethnically di...

    Authors: Ariel Rodriguez-Velazquez, Rosa Velez, Jean Carlo Lafontaine, Claudia B. Colon-Echevarria, Rocio D. Lamboy-Caraballo, Ingrid Ramirez, Adalberto Mendoza, Patricia Casbas-Hernandez and Guillermo N. Armaiz-Pena

    Citation: BMC Cancer 2018 18:1177

    Published on:

  16. Content type: Research article

    The incidence and mortality from prostate cancer is expected to increase in the next decade in Thailand. Despite the perceived lower risk in this population vs. developed, western countries, it is becoming an ...

    Authors: Christian S. Alvarez, Eduardo Villamor, Rafael Meza, Laura S. Rozek, Hutcha Sriplung and Alison M. Mondul

    Citation: BMC Cancer 2018 18:1175

    Published on:

  17. Content type: Research article

    To determine the psychometric properties and minimal clinically important differences (MCIDs) of the World Health Organization Quality of Life-BREF (WHOQOL-BREF) in advanced stage lung cancer patients.

    Authors: Mark de Mol, Sabine Visser, Joachim G. J. V. Aerts, Paul Lodder, Jolanda de Vries and Brenda L. den Oudsten

    Citation: BMC Cancer 2018 18:1173

    Published on:

  18. Content type: Research article

    There is evidence that derangement in serum electrolytes like sodium and potassium is associated with increased morbidity and mortality among hospitalized critically ill patients, but their role in the context...

    Authors: Arunangshu Ghoshal, Hans Garmo, Niklas Hammar, Ingmar Jungner, Håkan Malmström, Göran Walldius and Mieke Van Hemelrijck

    Citation: BMC Cancer 2018 18:1169

    Published on:

  19. Content type: Research article

    The effect of sleep duration on cancer risk remains controversial. We aimed to quantify the available evidence on this relationship using categorical and dose–response meta-analyses.

    Authors: Yuheng Chen, Fengwei Tan, Luopei Wei, Xin Li, Zhangyan Lyu, Xiaoshuang Feng, Yan Wen, Lanwei Guo, Jie He, Min Dai and Ni Li

    Citation: BMC Cancer 2018 18:1149

    Published on:

  20. Content type: Research article

    A minority of European countries have participated in international comparisons with high level data on lung cancer. However, the nature and extent of data collection across the continent is simply unknown, an...

    Authors: Anna Rich, David Baldwin, Inmaculada Alfageme, Paul Beckett, Thierry Berghmans, Stephen Brincat, Otto Burghuber, Alexandru Corlateanu, Tanja Cufer, Ronald Damhuis, Edvardas Danila, Joanna Domagala-Kulawik, Stefano Elia, Mina Gaga, Tuncay Goksel, Bogdan Grigoriu…

    Citation: BMC Cancer 2018 18:1144

    Published on:

  21. Content type: Research article

    Oesophageal carcinoma (OC) is one of the leading cancers in Sri Lanka. Its increasing incidence despite the implementation of various preventive activities addressing the conventional risk factors indicates th...

    Authors: Ishanka Ayeshwari Talagala, Metthananda Nawarathne and Carukshi Arambepola

    Citation: BMC Cancer 2018 18:1135

    Published on:

  22. Content type: Research article

    The French West-Indies rank first for both prostate cancer incidence and mortality rates. Analyzing diagnostic and therapeutic procedures among patients with prostate cancer, using data from a population-based...

    Authors: Clarisse Joachim, Jacqueline Veronique-Baudin, Stephen Ulric-Gervaise, Jonathan Macni, Thierry Almont, Olivier Pierre-Louis, Lidvine Godaert, Moustapha Drame, Jean-Luc Novella, Karim Farid, Vincent Vinh-Hung and Patrick Escarmant

    Citation: BMC Cancer 2018 18:1130

    Published on:

  23. Content type: Research article

    Liver fibrosis is involved in hepatocellular carcinoma (HCC), but its effect on the survival of patients with HCC remains controversial. This study aims to explore whether the severity of liver fibrosis has an...

    Authors: Hui Liu, Dong Cen, Yunxian Yu, Yanting Wang, Xiao Liang, Hui Lin and Xiujun Cai

    Citation: BMC Cancer 2018 18:1125

    Published on:

  24. Content type: Research article

    Neuroendocrine tumours are uncommon tumours; there is often a long period between the onset of symptoms and diagnosis. This study aims to address the symptoms prior to diagnosis of people with known neuroendoc...

    Authors: Ron Basuroy, Catherine Bouvier, John Keith Ramage, Maia Sissons and Raj Srirajaskanthan

    Citation: BMC Cancer 2018 18:1122

    Published on:

  25. Content type: Research article

    Survival rates of lung cancer remains poor and the impact of comorbidities on the prognosis is discussed. The objective of this study was to assess if the Charlson Comorbidity Index (CCI) was associated with 8...

    Authors: A. Seigneurin, P. Delafosse, B. Trétarre, A. S. Woronoff, M. Velten, P. Grosclaude, A. V. Guizard, B. Lapôtre-Ledoux, S. Bara, F. Molinié and M. Colonna

    Citation: BMC Cancer 2018 18:1091

    Published on:

  26. Content type: Research article

    We conducted a meta-analysis to evaluate the relationship between the glutathione S-transferase μ1 (GSTM1)– and glutathione S-transferase θ1 (GSTT1)– null genotypes and susceptibility to bladder cancer.

    Authors: Tianbiao Zhou, Hong-Yan Li, Wei-Ji Xie, Zhiqing Zhong, Hongzhen Zhong and Zhi-Jun Lin

    Citation: BMC Cancer 2018 18:1088

    Published on:

  27. Content type: Research article

    An increasing number of studies have identified spatial differences in colorectal cancer survival. However, little is known about the spatially varying effects of predictors in survival prediction modeling stu...

    Authors: Yu Tian, Jun Li, Tianshu Zhou, Danyang Tong, Shengqiang Chi, Xiangxing Kong, Kefeng Ding and Jingsong Li

    Citation: BMC Cancer 2018 18:1084

    Published on:

  28. Content type: Research article

    Breast and cervical cancers represent a significant cause of morbidity and mortality among women. The purpose of this study was to analyse the survival and time trends in two of the most common female cancers ...

    Authors: Allini Mafra da Costa, Dana Hashim, José Humberto Tavares Guerreiro Fregnani and Elisabete Weiderpass

    Citation: BMC Cancer 2018 18:1079

    Published on:

  29. Content type: Research article

    The contribution of genetic polymorphisms to the large inter-individual variation in mammographic density (MD) changes following starting and stopping use of estrogen and progestin combined therapy (EPT) has n...

    Authors: Eunjung Lee, Jianning Luo, Fredrick R. Schumacher, David Van Den Berg, Anna H. Wu, Daniel O. Stram, Leslie Bernstein and Giske Ursin

    Citation: BMC Cancer 2018 18:1072

    Published on:

  30. Content type: Research article

    Chronic myeloid leukemia is associated with a BCR/ABL oncoprotein inhibited by imatinib mesylate, the first tyrosine kinase inhibitor. Although experimental studies have clearly demonstrated the efficacy of im...

    Authors: Enza Di Felice, Francesca Roncaglia, Francesco Venturelli, Lucia Mangone, Stefano Luminari, Claudia Cirilli, Giuliano Carrozzi and Paolo Giorgi Rossi

    Citation: BMC Cancer 2018 18:1069

    Published on:

  31. Content type: Research article

    Data on the long-term risks of non-AIDS defining cancers (NADCs) are limited, especially in Asians. The incidence of NADCs may correlate with the epidemiological trend of cancers or oncogenic infection in each...

    Authors: Naoyoshi Nagata, Takeshi Nishijima, Ryota Niikura, Tetsuji Yokoyama, Yumi Matsushita, Koji Watanabe, Katsuji Teruya, Yoshimi Kikuchi, Junichi Akiyama, Mikio Yanase, Naomi Uemura, Shinichi Oka and Hiroyuki Gatanaga

    Citation: BMC Cancer 2018 18:1066

    Published on:

  32. Content type: Research article

    Physical activity reduces the risk of colorectal cancer (CRC), but the relevant evidence derives primarily from self-reported recreational and occupational activity. Less is known about the contribution of oth...

    Authors: Shahid Mahmood, Dallas R. English, Robert J. MacInnis, Amalia Karahalios, Neville Owen, Roger L. Milne, Graham G. Giles and Brigid M. Lynch

    Citation: BMC Cancer 2018 18:1063

    Published on:

  33. Content type: Research article

    Obesity has been associated with aggressive prostate cancer and poor outcomes. It is important to understand how prognostic tools for that guide prostate cancer treatment may be impacted by obesity. The goal o...

    Authors: Charnita Zeigler-Johnson, Aaron Hudson, Karen Glanz, Elaine Spangler and Knashawn H. Morales

    Citation: BMC Cancer 2018 18:1061

    Published on:

  34. Content type: Research article

    Ataxia telangiectasia mutated (ATM) gene plays a key role in response to DNA lesions and is related to the invasion and metastasis of malignancy. Epidemiological studies have indicated associations between ATM rs...

    Authors: Yulu Gu, Jikang Shi, Shuang Qiu, Yichun Qiao, Xin Zhang, Yi Cheng and Yawen Liu

    Citation: BMC Cancer 2018 18:1060

    Published on:

  35. Content type: Research article

    Doctors who work at cancer hospitals are at high risk of developing emotional distress. This study evaluated the prevalence of burnout, anxiety, and depression in a sample of oncologists of various specialties...

    Authors: Carlos Eduardo Paiva, Beatriz Parreira Martins and Bianca Sakamoto Ribeiro Paiva

    Citation: BMC Cancer 2018 18:1044

    Published on:

  36. Content type: Research article

    Among women with epithelial ovarian cancer (EOC), histotype is one of the major prognostic factors. However, few data are available on histotype- specific survival and mortality estimates among these patients....

    Authors: Nimisha Arora, Aline Talhouk, Jessica N. McAlpine, Michael R. Law and Gillian E. Hanley

    Citation: BMC Cancer 2018 18:1039

    Published on:

  37. Content type: Research article

    Among cancer patients, prior antidepressant use has been associated with impaired survival. This could be due to differences in stage at diagnosis, in receipt of treatment, or in treatment complications. The p...

    Authors: Ellen Hollands Steffensen, Clint Cary, Jørgen Bjerggaard Jensen, Heidi Larsson, Michael Weiner and Mette Nørgaard

    Citation: BMC Cancer 2018 18:1035

    Published on:

  38. Content type: Research article

    Cancer survivors may be at increased risk of cardiovascular diseases, but little is known about whether prescribing guidelines for the primary prevention of cardiovascular disease are adequately implemented in...

    Authors: Kendal Chidwick, Helen Strongman, Anthony Matthews, Susannah Stanway, Alexander R. Lyon, Liam Smeeth and Krishnan Bhaskaran

    Citation: BMC Cancer 2018 18:1018

    Published on:

  39. Content type: Research article

    Shared decision-making (SDM) is recommended for men facing prostate cancer (PC) screening decisions. We synthesize the evidence on the comparative effectiveness of SDM with usual care.

    Authors: Nahara Anani Martínez-González, Stefan Neuner-Jehle, Andreas Plate, Thomas Rosemann and Oliver Senn

    Citation: BMC Cancer 2018 18:1015

    Published on:

    The Correction to this article has been published in BMC Cancer 2018 18:1196

  40. Content type: Research article

    Territorial differences in the access to innovative anticancer drugs have been reported from many countries. The objectives of this study were to evaluate access to innovative treatments for metastatic lung ca...

    Authors: Arnaud Scherpereel, Isabelle Durand-Zaleski, François-Emery Cotté, Jérôme Fernandes, Didier Debieuvre, Cécile Blein, Anne-Françoise Gaudin, Charlène Tournier, Alexandre Vainchtock, Pierre Chauvin, Pierre-Jean Souquet, Virginie Westeel and Christos Chouaïd

    Citation: BMC Cancer 2018 18:1013

    Published on:

  41. Content type: Research article

    Receptor activator of nuclear factor kappa-B (RANK)-signaling is involved in tumor growth and spread in experimental models. Binding of RANK ligand (RANKL) to RANK activates signaling, which is inhibited by os...

    Authors: Danja Sarink, Helena Schock, Theron Johnson, Jenny Chang-Claude, Kim Overvad, Anja Olsen, Anne Tjønneland, Patrick Arveux, Agnès Fournier, Marina Kvaskoff, Heiner Boeing, Anna Karakatsani, Antonia Trichopoulou, Carlo La Vecchia, Giovanna Masala, Claudia Agnoli…

    Citation: BMC Cancer 2018 18:1010

    Published on:

  42. Content type: Research article

    The aim of this study was to determine the HPV positivity rate in patients with laryngeal cancer, and to determine the effect of HPV positivity on survival. An additional aim was to determine if patients with ...

    Authors: Ozlem Onerci Celebi, Ebru Sener, Sefik Hosal, Mustafa Cengiz, Ibrahim Gullu and Gaye Guler Tezel

    Citation: BMC Cancer 2018 18:1005

    Published on:

  43. Content type: Research article

    Epidemiologists are beginning to employ metabolomics and lipidomics with archived blood from incident cases and controls to discover causes of cancer. Although several such studies have focused on colorectal c...

    Authors: Kelsi Perttula, Courtney Schiffman, William M B Edmands, Lauren Petrick, Hasmik Grigoryan, Xiaoming Cai, Marc J Gunter, Alessio Naccarati, Silvia Polidoro, Sandrine Dudoit, Paolo Vineis and Stephen M Rappaport

    Citation: BMC Cancer 2018 18:996

    Published on:

  44. Content type: Research article

    Sarcomas are rare, heterogeneous tumours affecting patients of any age. Previous surveys describe that sarcoma patients report a significantly worse experience than those with common cancers. Consequently, Sar...

    Authors: Eugenie Younger, Olga Husson, Lindsey Bennister, Jeremy Whelan, Roger Wilson, Andy Roast, Robin L Jones and Winette TA van der Graaf

    Citation: BMC Cancer 2018 18:991

    Published on:

  45. Content type: Research article

    Survival of esophageal cancer in Linzhou was seen to increase over the past few decades and is higher than the average level of China due to the implementation of comprehensive prevention and control measures....

    Authors: Shuzheng Liu, Lanwei Guo, Qiong Chen, Liang Yu, Bianyun Li, Xiaoqin Cao and Xibin Sun

    Citation: BMC Cancer 2018 18:949

    Published on: