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Epidemiology, prevention and public health

This section aims to consider publications which focus on all aspects of cancer epidemiology including risk factors for disease initiation and development, social determinants, environmental, behavioural, and occupational correlates, and the impact of health policies, practices and interventions on the community.

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  1. Philadelphia (Ph) chromosome-negative myeloproliferative neoplasms (MPNs) are a heterogeneous group of hematopoietic stem cell clonal diseases. Most patients with MPN are asymptomatic at diagnosis although som...

    Authors: Tarinee Rungjirajittranon, Weerapat Owattanapanich, Patompong Ungprasert, Noppadol Siritanaratkul and Theera Ruchutrakool

    Citation: BMC Cancer 2019 19:184

    Content type: Research article

    Published on:

  2. Although rare cancers account for 27% of cancer diagnoses in the US, there is insufficient research on survivorship issues in these patients. An important issue cancer survivors face is an elevated risk of bei...

    Authors: Dianne M. Finkelstein, Nora K. Horick, Ritesh Ramchandani, Kristina L. Boyd, Huma Q. Rana and Brittany L. Bychkovsky

    Citation: BMC Cancer 2019 19:166

    Content type: Research article

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  3. The association of ABO blood groups with gastric cancer risk was proposed decades ago, but the results have been inconsistent.

    Authors: Yingying Mao, Wenjun Yang, Qi Qi, Fei Yu, Tianpei Wang, Hongfei Zhang, Juncheng Dai, Hongxia Ma, Zhibin Hu, Hongbing Shen, Gang Li and Guangfu Jin

    Citation: BMC Cancer 2019 19:164

    Content type: Research article

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  4. The aim of this study was to evaluate the prevalence of some gynecological cancer risk factors in a population of female relatives of cancer patients in Hacettepe University Oncology Hospital. Additionally, wh...

    Authors: Nooria Atta, Saadettin Kilickap, Deniz Yuce and Mutlu Hayran

    Citation: BMC Cancer 2019 19:154

    Content type: Research article

    Published on:

  5. Chemotherapy-induced thrombocytopenia (CIT) is a potentially serious complication that can lead to chemotherapy dose delays, dose reductions, or discontinuation, and increases the risk of serious bleeding even...

    Authors: Derek Weycker, Mark Hatfield, Aaron Grossman, Ahuva Hanau, Alex Lonshteyn, Anjali Sharma and David Chandler

    Citation: BMC Cancer 2019 19:151

    Content type: Research article

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  7. The brain is a common site for metastasis in non-small-cell lung cancer (NSCLC). This study was designed to evaluate the relationship between the mutational of the epidermal growth factor receptor (EGFR) and o...

    Authors: Wen-Ya Li, Ting-Ting Zhao, Hui-Mian Xu, Zhen-Ning Wang, Ying-Ying Xu, Yunan Han, Yong-Xi Song, Jian-Hua Wu, Hao Xu, Song-Cheng Yin, Xing-Yu Liu and Zhi-Feng Miao

    Citation: BMC Cancer 2019 19:145

    Content type: Research article

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  8. Evidence from clinical trials suggests that the addition of bevacizumab to chemotherapy in the first-line treatment of patients with HER2-negative metastatic breast cancer improves progression-free survival (P...

    Authors: Audrey Petitjean, Jayne Smith-Palmer, William Valentine, Bertrand Tehard and Stephané Roze

    Citation: BMC Cancer 2019 19:140

    Content type: Research article

    Published on:

  9. Intracranial and intraspinal tumours are the most numerous solid tumours in children. Some recently defined subtypes are relatively frequent in childhood. Many cancer registries routinely ascertain CNS tumours...

    Authors: Charles A. Stiller, Anita M. Bayne, Aruna Chakrabarty, Tom Kenny and Paul Chumas

    Citation: BMC Cancer 2019 19:139

    Content type: Research article

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  10. Considering the lack of efficient breast cancer prediction models suitable for general population screening in China. We aimed to develop a risk prediction model to identify high-risk populations, to help with...

    Authors: Lu Wang, Liyuan Liu, Zhen Lou, Lijie Ding, Hui Guan, Fei Wang, Lixiang Yu, Yujuan Xiang, Fei Zhou, Fuzhong Xue and Zhigang Yu

    Citation: BMC Cancer 2019 19:128

    Content type: Research article

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  11. The prognostic value of Ki-67 expression in colorectal cancer patients was controversial. Therefore, this meta analysis was conducted to ascertain the prognostic value of Ki-67 expression in colorectal cancer ...

    Authors: Zhao-Wen Luo, Ming-Gu Zhu, Zhi-Qiao Zhang, Feng-Jun Ye, Wen-Heng Huang and Xue-Zhang Luo

    Citation: BMC Cancer 2019 19:123

    Content type: Research article

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  12. The Swiss Federal Office of Public Health has recommended vaccination against human papillomavirus (HPV) to prevent cervical cancer since 2008. To establish monitoring of the future public health impact of vac...

    Authors: Dianne Egli-Gany, Anne Spaar Zographos, Joachim Diebold, Virginie Masserey Spicher, Brigitte Frey Tirri, Rolf Heusser, Joakim Dillner, Patrick Petignat, Roland Sahli and Nicola Low

    Citation: BMC Cancer 2019 19:111

    Content type: Research article

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  13. Breast cancer prognosis has dramatically improved over 40 years. There is, however, no proof of population ‘cure’. This research aimed to examine the pattern of long-term excess mortality due to breast cancer ...

    Authors: R. Schaffar, A. Belot, B. Rachet and L. Woods

    Citation: BMC Cancer 2019 19:107

    Content type: Research article

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  14. Epidemiological research on small cell lung cancer (SCLC) is limited and based on cancer registry data. We evaluated the feasibility and validity of using primary care electronic health records (The Health Imp...

    Authors: Lucía Cea Soriano, Jihong Zong and Luis A. García Rodríguez

    Citation: BMC Cancer 2019 19:91

    Content type: Research article

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  15. A sizeable body of evidence suggests that statins can cease breast cancer progression and prevent breast cancer recurrence. The latest studies have, however, not been supportive of such clinically beneficial e...

    Authors: Signe Borgquist, Per Broberg, Jasaman Tojjar and Håkan Olsson

    Citation: BMC Cancer 2019 19:54

    Content type: Research article

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  17. To date, no single colorectal cancer (CRC) screening strategy has been determined to be applicable worldwide. In China, a CRC screening protocol that combines double fecal immunochemical tests (FITs) and a hig...

    Authors: Shan-Rong Cai, Yan-Qin Huang, Su-Zhan Zhang, Qi-Rong Li, Xin Yuan Ma and Shu Zheng

    Citation: BMC Cancer 2019 19:47

    Content type: Research article

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  18. Transitional cell carcinoma (TCC) accounts for around 95% of bladder cancers and is the 4th most common cancer among men and the tenth most common in women, in the US. There is a constant need to clarify curre...

    Authors: Muneer J. Al-Husseini, Ahmad Kunbaz, Anas M. Saad, João Vasco Santos, Sami Salahia, Marium Iqbal and Fares Alahdab

    Citation: BMC Cancer 2019 19:46

    Content type: Research article

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  19. In Canada, clinical practice guidelines recommend breast cancer screening, but there are gaps in adherence to recommendations for screening, particularly among certain hard-to-reach populations, that may diffe...

    Authors: A. K. Lofters, M. L. McBride, D. Li, M. Whitehead, R. Moineddin, L. Jiang, E. Grunfeld and P. A. Groome

    Citation: BMC Cancer 2019 19:42

    Content type: Research article

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  20. Cancer imposes substantial burdens on cancer suffers, their families and the health system, especially in the end of life (EOL) of care patients. There are few developing country studies of EOL health care cos...

    Authors: Anli Leng, Jun Jing, Stephen Nicholas and Jian Wang

    Citation: BMC Cancer 2019 19:39

    Content type: Research article

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  21. Single nucleotide polymorphisms (SNPs) in 3′-untranslated region (UTR) of genes related with cell-matrix adhesions and migration might affect miRNA binding and potentially affect the risk of cancer. The presen...

    Authors: Shouchun Yan, Rong Sun, Shan Wu, Tianbo Jin, Shanshan Zhang, Fanglin Niu, Jingjie Li and Mingwei Chen

    Citation: BMC Cancer 2019 19:35

    Content type: Research article

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  22. Lung cancer is typically diagnosed at a late stage. Early presentation and detection of lung cancer symptoms is critical to improving survival but can be clinically complicated and as yet a robust screening me...

    Authors: Shemana Cassim, Lynne Chepulis, Rawiri Keenan, Jacquie Kidd, Melissa Firth and Ross Lawrenson

    Citation: BMC Cancer 2019 19:25

    Content type: Research article

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  23. Male Breast Cancer (MBC) is rare, which makes its understanding and treatment be extrapolated from what is known about the occurrence in women, with few epidemiological studies. Therefore, the aim of the prese...

    Authors: Jean Henri Maselli-Schoueri, Fernando Alves Affonso-Kaufman, Claudia Vaz de Melo Sette, Francisco Winter dos Santos Figueiredo and Fernando Adami

    Citation: BMC Cancer 2019 19:23

    Content type: Research article

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  24. Nutrition labeling has been found to affect the amount and type of food intake, with certain groups in the population, such as cancer survivors, being more aware of this information. A higher awareness of nutr...

    Authors: Ji Sung Yoo, Kyu-Tae Han, Seung Hyun Chung and Eun-Cheol Park

    Citation: BMC Cancer 2019 19:16

    Content type: Research article

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  25. Metachronous cancer in patients with head and neck cancer (HNC) is common and is associated with a poor prognosis. We aimed to evaluate the incidence of metachronous cancer at different sites according to age ...

    Authors: Taro Iwatsubo, Ryu Ishihara, Toshitaka Morishima, Akira Maekawa, Kentaro Nakagawa, Masamichi Arao, Masayasu Ohmori, Hiroyoshi Iwagami, Kenshi Matsuno, Shuntaro Inoue, Hiroko Nakahira, Noriko Matsuura, Satoki Shichijo, Takashi Kanesaka, Sachiko Yamamoto, Yoji Takeuchi…

    Citation: BMC Cancer 2019 19:3

    Content type: Research article

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  26. Physical fitness and psychosocial function is often reduced in children during or shortly after cancer treatment. This study evaluates the effect of a combined physical exercise and psychosocial intervention o...

    Authors: Katja I. Braam, Elisabeth M. van Dijk-Lokkart, Gertjan J. L. Kaspers, Tim Takken, Jaap Huisman, Laurien M. Buffart, Marc B. Bierings, Johannes H. M. Merks, Marry M. van den Heuvel-Eibrink, Margreet A. Veening and Eline van Dulmen-den Broeder

    Citation: BMC Cancer 2018 18:1289

    Content type: Research article

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  27. The prevalence and distribution of histologically diagnosed breast disease are not well documented in low income countries, Uganda inclusive. Although the greater majority of breast lesions globally are benign...

    Authors: Salvatore Ssemmanda, Eric Katagirya, Phiona Bukirwa, David Alele, Robert Lukande and Samuel Kalungi

    Citation: BMC Cancer 2018 18:1285

    Content type: Research article

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  28. Few epidemiologic findings are as well established as the association between smoking and lung cancer. It is therefore somewhat surprising that there is not yet a clear consensus about the exposure-response re...

    Authors: T. Remen, J. Pintos, M. Abrahamowicz and J. Siemiatycki

    Citation: BMC Cancer 2018 18:1275

    Content type: Research article

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  29. Kaposi’s sarcoma (KS) is a multifocal angioproliferative tumor involving blood and lymphatic vessels, caused by Human Herpes Virus-8 (HHV-8). KS is an important AIDS-defining tumor with high prevalence in Sub-...

    Authors: George P. Semango, Renard M. Charles, Consolata I. Swai, Alex Mremi, Patrick Amsi, Tolbert Sonda, Elichilia R. Shao, Daudi R. Mavura, Leo A. B. Joosten, Elingarami Sauli and Mramba Nyindo

    Citation: BMC Cancer 2018 18:1258

    Content type: Research article

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  31. Diabetes mellitus (DM) is associated with poorer outcomes in some cancers. Its effect on ovarian cancer is less clear. We consider the effect of DM on overall survival (OS) and progression free survival (PFS) ...

    Authors: Setareh Akhavan, Akram Ghahghaei-Nezamabadi, Mitra Modaresgilani, Azam Sadat Mousavi, Mahdi Sepidarkish, Afsaneh Tehranian and Elahe Rezayof

    Citation: BMC Cancer 2018 18:1246

    Content type: Research article

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  34. Myeloid-derived suppressor cells (MDSCs) is a heterogeneous population of immature myeloid cells, inhibiting both the innate and adaptive immunity. Recent studies validated that MDSCs caused immune suppression...

    Authors: Lisha Ai, Shidai Mu, Yadan Wang, Huafang Wang, Li Cai, Wenzhu Li and Yu Hu

    Citation: BMC Cancer 2018 18:1220

    Content type: Research article

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  35. Colorectal cancer (CRC) remains the second most common cancer in women worldwide. Physical activity (PA) has been associated with reduced risk of CRC; however, this has been demonstrated more consistently in m...

    Authors: Sunday Oluwafemi Oyeyemi, Tonje Braaten, Idlir Licaj, Eiliv Lund and Kristin Benjaminsen Borch

    Citation: BMC Cancer 2018 18:1216

    Content type: Research article

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  36. There are racial/ethnic disparities in breast cancer mortality may be attributed to differences in receipt of adjuvant cancer treatment. Our purpose was to determine whether the mortality disparities could be ...

    Authors: Albert J. Farias, Wen-Hsing Wu and Xianglin L. Du

    Citation: BMC Cancer 2018 18:1214

    Content type: Research article

    Published on:

  37. Epidemiological studies and cardiovascular prevention trials have shown that low-dose aspirin can reduce colorectal cancer (CRC) incidence and mortality, including inhibition of distant metastases. Metformin h...

    Authors: Marilena Petrera, Laura Paleari, Matteo Clavarezza, Matteo Puntoni, Silvia Caviglia, Irene Maria Briata, Massimo Oppezzi, Eva Mihajlovic Mislej, Borut Stabuc, Michael Gnant, Thomas Bachleitner-Hofmann, Wilfried Roth, Dominique Scherer, Walter-E. Haefeli, Cornelia M. Ulrich and Andrea DeCensi

    Citation: BMC Cancer 2018 18:1210

    Content type: Study protocol

    Published on:

  38. Timely assessment of cancer risk from current radiation exposure among medical radiation workers can contribute to the development of strategies to prevent excessive occupational radiation exposure. The purpos...

    Authors: Won Jin Lee, Yeongchull Choi, Seulki Ko, Eun Shil Cha, Jaeyoung Kim, Young Min Kim, Kyoung Ae Kong, Songwon Seo, Ye Jin Bang and Yae Won Ha

    Citation: BMC Cancer 2018 18:1206

    Content type: Research article

    Published on:

  39. Mammographic density is a known risk factor for breast cancer, but the underlying pathologic characteristics are not well understood. The current analysis investigated the expression of several markers of inte...

    Authors: Gertraud Maskarinec, Dan Ju, Jaimie Fong, David Horio, Owen Chan, Lenora W. M. Loo and Brenda Y. Hernandez

    Citation: BMC Cancer 2018 18:1191

    Content type: Research article

    Published on:

  40. Previous epidemiological studies aimed at describing characteristics of breast (BC) and ovarian cancer (OC) patients tend to examine Hispanic populations using a mix of individuals that come from ethnically di...

    Authors: Ariel Rodriguez-Velazquez, Rosa Velez, Jean Carlo Lafontaine, Claudia B. Colon-Echevarria, Rocio D. Lamboy-Caraballo, Ingrid Ramirez, Adalberto Mendoza, Patricia Casbas-Hernandez and Guillermo N. Armaiz-Pena

    Citation: BMC Cancer 2018 18:1177

    Content type: Research article

    Published on:

  41. The incidence and mortality from prostate cancer is expected to increase in the next decade in Thailand. Despite the perceived lower risk in this population vs. developed, western countries, it is becoming an ...

    Authors: Christian S. Alvarez, Eduardo Villamor, Rafael Meza, Laura S. Rozek, Hutcha Sriplung and Alison M. Mondul

    Citation: BMC Cancer 2018 18:1175

    Content type: Research article

    Published on:

  42. To determine the psychometric properties and minimal clinically important differences (MCIDs) of the World Health Organization Quality of Life-BREF (WHOQOL-BREF) in advanced stage lung cancer patients.

    Authors: Mark de Mol, Sabine Visser, Joachim G. J. V. Aerts, Paul Lodder, Jolanda de Vries and Brenda L. den Oudsten

    Citation: BMC Cancer 2018 18:1173

    Content type: Research article

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  43. There is evidence that derangement in serum electrolytes like sodium and potassium is associated with increased morbidity and mortality among hospitalized critically ill patients, but their role in the context...

    Authors: Arunangshu Ghoshal, Hans Garmo, Niklas Hammar, Ingmar Jungner, Håkan Malmström, Göran Walldius and Mieke Van Hemelrijck

    Citation: BMC Cancer 2018 18:1169

    Content type: Research article

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  44. The effect of sleep duration on cancer risk remains controversial. We aimed to quantify the available evidence on this relationship using categorical and dose–response meta-analyses.

    Authors: Yuheng Chen, Fengwei Tan, Luopei Wei, Xin Li, Zhangyan Lyu, Xiaoshuang Feng, Yan Wen, Lanwei Guo, Jie He, Min Dai and Ni Li

    Citation: BMC Cancer 2018 18:1149

    Content type: Research article

    Published on:

  45. A minority of European countries have participated in international comparisons with high level data on lung cancer. However, the nature and extent of data collection across the continent is simply unknown, an...

    Authors: Anna Rich, David Baldwin, Inmaculada Alfageme, Paul Beckett, Thierry Berghmans, Stephen Brincat, Otto Burghuber, Alexandru Corlateanu, Tanja Cufer, Ronald Damhuis, Edvardas Danila, Joanna Domagala-Kulawik, Stefano Elia, Mina Gaga, Tuncay Goksel, Bogdan Grigoriu…

    Citation: BMC Cancer 2018 18:1144

    Content type: Research article

    Published on:

  46. Oesophageal carcinoma (OC) is one of the leading cancers in Sri Lanka. Its increasing incidence despite the implementation of various preventive activities addressing the conventional risk factors indicates th...

    Authors: Ishanka Ayeshwari Talagala, Metthananda Nawarathne and Carukshi Arambepola

    Citation: BMC Cancer 2018 18:1135

    Content type: Research article

    Published on:

  47. The French West-Indies rank first for both prostate cancer incidence and mortality rates. Analyzing diagnostic and therapeutic procedures among patients with prostate cancer, using data from a population-based...

    Authors: Clarisse Joachim, Jacqueline Veronique-Baudin, Stephen Ulric-Gervaise, Jonathan Macni, Thierry Almont, Olivier Pierre-Louis, Lidvine Godaert, Moustapha Drame, Jean-Luc Novella, Karim Farid, Vincent Vinh-Hung and Patrick Escarmant

    Citation: BMC Cancer 2018 18:1130

    Content type: Research article

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  48. Liver fibrosis is involved in hepatocellular carcinoma (HCC), but its effect on the survival of patients with HCC remains controversial. This study aims to explore whether the severity of liver fibrosis has an...

    Authors: Hui Liu, Dong Cen, Yunxian Yu, Yanting Wang, Xiao Liang, Hui Lin and Xiujun Cai

    Citation: BMC Cancer 2018 18:1125

    Content type: Research article

    Published on:

  49. Neuroendocrine tumours are uncommon tumours; there is often a long period between the onset of symptoms and diagnosis. This study aims to address the symptoms prior to diagnosis of people with known neuroendoc...

    Authors: Ron Basuroy, Catherine Bouvier, John Keith Ramage, Maia Sissons and Raj Srirajaskanthan

    Citation: BMC Cancer 2018 18:1122

    Content type: Research article

    Published on:

  50. Survival rates of lung cancer remains poor and the impact of comorbidities on the prognosis is discussed. The objective of this study was to assess if the Charlson Comorbidity Index (CCI) was associated with 8...

    Authors: A. Seigneurin, P. Delafosse, B. Trétarre, A. S. Woronoff, M. Velten, P. Grosclaude, A. V. Guizard, B. Lapôtre-Ledoux, S. Bara, F. Molinié and M. Colonna

    Citation: BMC Cancer 2018 18:1091

    Content type: Research article

    Published on:

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