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Epidemiology, prevention and public health

This section aims to consider publications which focus on all aspects of cancer epidemiology including risk factors for disease initiation and development, social determinants, environmental, behavioural, and occupational correlates, and the impact of health policies, practices and interventions on the community.

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  1. Content type: Research article

    Recently, the concept of “late presentation with viral hepatitis” was introduced to help quantify the proportion of patients missing timely diagnosis and treatment for viral hepatitis. The clinical implication...

    Authors: Dong Hyun Sinn, Danbee Kang, Minwoong Kang, Seung Woon Paik, Eliseo Guallar, Juhee Cho and Geum-Youn Gwak

    Citation: BMC Cancer 2019 19:286

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  2. Content type: Research article

    There is limited information on changes over time in carcinoid syndrome (CS) symptoms and quality of life (QoL). This study assessed change in CS symptoms and QoL in patients treated with somatostatin analogs ...

    Authors: Daniel M. Halperin, Lynn Huynh, Jennifer L. Beaumont, Beilei Cai, Rachel H. Bhak, Sahil Narkhede, Todor Totev, Mei S. Duh, Maureen P. Neary and David Cella

    Citation: BMC Cancer 2019 19:274

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  3. Content type: Research article

    Cardiovascular medications may be associated with cancer development, but little is known about their association with cancer recurrence. Medications such as statins and antihypertensives may be commonly used ...

    Authors: Erin J. A. Bowles, Onchee Yu, Rebecca Ziebell, Lu Chen, Denise M. Boudreau, Debra P. Ritzwoller, Rebecca A. Hubbard, Jennifer M. Boggs, Andrea N. Burnett-Hartman, Andrew Sterrett, Monica Fujii and Jessica Chubak

    Citation: BMC Cancer 2019 19:270

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  4. Content type: Research article

    Data from population-based cancer registries (PBCRs) are a useful resource for estimating the incidence of cancers. PBCR data is useful in the planning and implementation of cancer prevention and control strat...

    Authors: Yaw Ampem Amoako, Baffour Awuah, Rita Larsen-Reindorf, Fred Kwame Awittor, Gloria Kyem, Kwame Ofori-Boadu, Ernest Osei-Bonsu and Dennis Odai Laryea

    Citation: BMC Cancer 2019 19:267

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  5. Content type: Research article

    Although men carry a higher risk of hepatocellular carcinoma (HCC) than women, it is still controversial whether men also have a poorer postoperative prognosis. A retrospective study was conducted to evaluate ...

    Authors: Ming-Wei Lai, Yu-De Chu, Chih-Lang Lin, Rong-Nan Chien, Ta-Sen Yeh, Tai-Long Pan, Po-Yuan Ke, Kwang-Hui Lin and Chau-Ting Yeh

    Citation: BMC Cancer 2019 19:250

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  6. Content type: Research article

    Cancer indicators are essential information for cancer surveillance and cancer research strategy development. The Martinique Cancer Registry (MCR) is a population-based cancer Registry (PBCR) that has been rec...

    Authors: Clarisse Joachim, Jacqueline Veronique-Baudin, Stephen Ulric-Gervaise, Audrey Pomier, Aimée Pierre-Louis, Mylène Vestris, Jean-Luc Novella, Moustapha Drame, Jonathan Macni and Patrick Escarmant

    Citation: BMC Cancer 2019 19:239

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  7. Content type: Research article

    The purpose of the present study was to characterize the prevalence, associated factors, and to construct a nomogram for predicting bone metastasis (BM) with different histological types of lung cancer.

    Authors: Chao Zhang, Min Mao, Xu Guo, Ping Cui, Lianmin Zhang, Yao Xu, Lili Li, Xiuxin Han, Karl Peltzer, Shunbin Xiong, Vladimir P. Baklaushev, Xin Wang and Guowen Wang

    Citation: BMC Cancer 2019 19:238

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  8. Content type: Research article

    Breast cancer is the most common cancer in women worldwide, with a great diversity in outcomes among individual patients. The ability to accurately predict a breast cancer outcome is important to patients, phy...

    Authors: Minh Tung Phung, Sandar Tin Tin and J. Mark Elwood

    Citation: BMC Cancer 2019 19:230

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  9. Content type: Research article

    Despite strong evidence of benefit, breast cancer risk assessment and chemoprevention are underutilized by primary care physicians. This study evaluates the impact of an educational program on knowledge and ut...

    Authors: Siddhartha Yadav, Sarah Hartkop, Paola Yumpo Cardenas, Rand Ladkany, Alexandra Halalau, Sandor Shoichet, Michael Maddens and Dana Zakalik

    Citation: BMC Cancer 2019 19:228

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  10. Content type: Research article

    The gastric cancer incidence rate differs widely across geographical areas. In Italy, in the province of Cremona the incidence is high, compared to the national situation. For this reason a specialized populat...

    Authors: B. M. Donida, G. Tomasello, M. Ghidini, F. Buffoli, M. Grassi, W. Liguigli, G. Maglietta, L. Pergola, M. Ratti, G. Sabadini, L. Toppo, M. Ungari and R. Passalacqua

    Citation: BMC Cancer 2019 19:212

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  11. Content type: Research article

    Recurrence is not explicitly documented in cancer registry data that are widely used for research. Patterns of events after initial treatment such as oncology visits, re-operation, and receipt of subsequent ch...

    Authors: Yuan Xu, Shiying Kong, Winson Y. Cheung, Antoine Bouchard-Fortier, Joseph C. Dort, Hude Quan, Elizabeth M. Buie, Geoff McKinnon and May Lynn Quan

    Citation: BMC Cancer 2019 19:210

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  12. Content type: Research article

    The length of interval between successive childbirths (birth interval) might influence the incidence of breast cancer, either by stimulating or by inhibiting the factors that are responsible for the initiation...

    Authors: Sushmita Katuwal, Juha S. Tapanainen, Eero Pukkala and Antti Kauppila

    Citation: BMC Cancer 2019 19:199

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  13. Content type: Research article

    Philadelphia (Ph) chromosome-negative myeloproliferative neoplasms (MPNs) are a heterogeneous group of hematopoietic stem cell clonal diseases. Most patients with MPN are asymptomatic at diagnosis although som...

    Authors: Tarinee Rungjirajittranon, Weerapat Owattanapanich, Patompong Ungprasert, Noppadol Siritanaratkul and Theera Ruchutrakool

    Citation: BMC Cancer 2019 19:184

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  14. Content type: Research article

    Although rare cancers account for 27% of cancer diagnoses in the US, there is insufficient research on survivorship issues in these patients. An important issue cancer survivors face is an elevated risk of bei...

    Authors: Dianne M. Finkelstein, Nora K. Horick, Ritesh Ramchandani, Kristina L. Boyd, Huma Q. Rana and Brittany L. Bychkovsky

    Citation: BMC Cancer 2019 19:166

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  15. Content type: Research article

    The association of ABO blood groups with gastric cancer risk was proposed decades ago, but the results have been inconsistent.

    Authors: Yingying Mao, Wenjun Yang, Qi Qi, Fei Yu, Tianpei Wang, Hongfei Zhang, Juncheng Dai, Hongxia Ma, Zhibin Hu, Hongbing Shen, Gang Li and Guangfu Jin

    Citation: BMC Cancer 2019 19:164

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  16. Content type: Research article

    The aim of this study was to evaluate the prevalence of some gynecological cancer risk factors in a population of female relatives of cancer patients in Hacettepe University Oncology Hospital. Additionally, wh...

    Authors: Nooria Atta, Saadettin Kilickap, Deniz Yuce and Mutlu Hayran

    Citation: BMC Cancer 2019 19:154

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  17. Content type: Research article

    Chemotherapy-induced thrombocytopenia (CIT) is a potentially serious complication that can lead to chemotherapy dose delays, dose reductions, or discontinuation, and increases the risk of serious bleeding even...

    Authors: Derek Weycker, Mark Hatfield, Aaron Grossman, Ahuva Hanau, Alex Lonshteyn, Anjali Sharma and David Chandler

    Citation: BMC Cancer 2019 19:151

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  18. Content type: Research article

    The brain is a common site for metastasis in non-small-cell lung cancer (NSCLC). This study was designed to evaluate the relationship between the mutational of the epidermal growth factor receptor (EGFR) and o...

    Authors: Wen-Ya Li, Ting-Ting Zhao, Hui-Mian Xu, Zhen-Ning Wang, Ying-Ying Xu, Yunan Han, Yong-Xi Song, Jian-Hua Wu, Hao Xu, Song-Cheng Yin, Xing-Yu Liu and Zhi-Feng Miao

    Citation: BMC Cancer 2019 19:145

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  19. Content type: Research article

    Evidence from clinical trials suggests that the addition of bevacizumab to chemotherapy in the first-line treatment of patients with HER2-negative metastatic breast cancer improves progression-free survival (P...

    Authors: Audrey Petitjean, Jayne Smith-Palmer, William Valentine, Bertrand Tehard and Stephané Roze

    Citation: BMC Cancer 2019 19:140

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  20. Content type: Research article

    Intracranial and intraspinal tumours are the most numerous solid tumours in children. Some recently defined subtypes are relatively frequent in childhood. Many cancer registries routinely ascertain CNS tumours...

    Authors: Charles A. Stiller, Anita M. Bayne, Aruna Chakrabarty, Tom Kenny and Paul Chumas

    Citation: BMC Cancer 2019 19:139

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  21. Content type: Research article

    Considering the lack of efficient breast cancer prediction models suitable for general population screening in China. We aimed to develop a risk prediction model to identify high-risk populations, to help with...

    Authors: Lu Wang, Liyuan Liu, Zhen Lou, Lijie Ding, Hui Guan, Fei Wang, Lixiang Yu, Yujuan Xiang, Fei Zhou, Fuzhong Xue and Zhigang Yu

    Citation: BMC Cancer 2019 19:128

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  22. Content type: Research article

    The prognostic value of Ki-67 expression in colorectal cancer patients was controversial. Therefore, this meta analysis was conducted to ascertain the prognostic value of Ki-67 expression in colorectal cancer ...

    Authors: Zhao-Wen Luo, Ming-Gu Zhu, Zhi-Qiao Zhang, Feng-Jun Ye, Wen-Heng Huang and Xue-Zhang Luo

    Citation: BMC Cancer 2019 19:123

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  23. Content type: Research article

    The Swiss Federal Office of Public Health has recommended vaccination against human papillomavirus (HPV) to prevent cervical cancer since 2008. To establish monitoring of the future public health impact of vac...

    Authors: Dianne Egli-Gany, Anne Spaar Zographos, Joachim Diebold, Virginie Masserey Spicher, Brigitte Frey Tirri, Rolf Heusser, Joakim Dillner, Patrick Petignat, Roland Sahli and Nicola Low

    Citation: BMC Cancer 2019 19:111

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  24. Content type: Research article

    Breast cancer prognosis has dramatically improved over 40 years. There is, however, no proof of population ‘cure’. This research aimed to examine the pattern of long-term excess mortality due to breast cancer ...

    Authors: R. Schaffar, A. Belot, B. Rachet and L. Woods

    Citation: BMC Cancer 2019 19:107

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  25. Content type: Research article

    Epidemiological research on small cell lung cancer (SCLC) is limited and based on cancer registry data. We evaluated the feasibility and validity of using primary care electronic health records (The Health Imp...

    Authors: Lucía Cea Soriano, Jihong Zong and Luis A. García Rodríguez

    Citation: BMC Cancer 2019 19:91

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  26. Content type: Research article

    A sizeable body of evidence suggests that statins can cease breast cancer progression and prevent breast cancer recurrence. The latest studies have, however, not been supportive of such clinically beneficial e...

    Authors: Signe Borgquist, Per Broberg, Jasaman Tojjar and Håkan Olsson

    Citation: BMC Cancer 2019 19:54

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  27. Content type: Research article

    To date, no single colorectal cancer (CRC) screening strategy has been determined to be applicable worldwide. In China, a CRC screening protocol that combines double fecal immunochemical tests (FITs) and a hig...

    Authors: Shan-Rong Cai, Yan-Qin Huang, Su-Zhan Zhang, Qi-Rong Li, Xin Yuan Ma and Shu Zheng

    Citation: BMC Cancer 2019 19:47

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  28. Content type: Research article

    Transitional cell carcinoma (TCC) accounts for around 95% of bladder cancers and is the 4th most common cancer among men and the tenth most common in women, in the US. There is a constant need to clarify curre...

    Authors: Muneer J. Al-Husseini, Ahmad Kunbaz, Anas M. Saad, João Vasco Santos, Sami Salahia, Marium Iqbal and Fares Alahdab

    Citation: BMC Cancer 2019 19:46

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  29. Content type: Research article

    In Canada, clinical practice guidelines recommend breast cancer screening, but there are gaps in adherence to recommendations for screening, particularly among certain hard-to-reach populations, that may diffe...

    Authors: A. K. Lofters, M. L. McBride, D. Li, M. Whitehead, R. Moineddin, L. Jiang, E. Grunfeld and P. A. Groome

    Citation: BMC Cancer 2019 19:42

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  30. Content type: Research article

    Cancer imposes substantial burdens on cancer suffers, their families and the health system, especially in the end of life (EOL) of care patients. There are few developing country studies of EOL health care cos...

    Authors: Anli Leng, Jun Jing, Stephen Nicholas and Jian Wang

    Citation: BMC Cancer 2019 19:39

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  31. Content type: Research article

    Single nucleotide polymorphisms (SNPs) in 3′-untranslated region (UTR) of genes related with cell-matrix adhesions and migration might affect miRNA binding and potentially affect the risk of cancer. The presen...

    Authors: Shouchun Yan, Rong Sun, Shan Wu, Tianbo Jin, Shanshan Zhang, Fanglin Niu, Jingjie Li and Mingwei Chen

    Citation: BMC Cancer 2019 19:35

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  32. Content type: Research article

    Lung cancer is typically diagnosed at a late stage. Early presentation and detection of lung cancer symptoms is critical to improving survival but can be clinically complicated and as yet a robust screening me...

    Authors: Shemana Cassim, Lynne Chepulis, Rawiri Keenan, Jacquie Kidd, Melissa Firth and Ross Lawrenson

    Citation: BMC Cancer 2019 19:25

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  33. Content type: Research article

    Male Breast Cancer (MBC) is rare, which makes its understanding and treatment be extrapolated from what is known about the occurrence in women, with few epidemiological studies. Therefore, the aim of the prese...

    Authors: Jean Henri Maselli-Schoueri, Fernando Alves Affonso-Kaufman, Claudia Vaz de Melo Sette, Francisco Winter dos Santos Figueiredo and Fernando Adami

    Citation: BMC Cancer 2019 19:23

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  34. Content type: Research article

    Nutrition labeling has been found to affect the amount and type of food intake, with certain groups in the population, such as cancer survivors, being more aware of this information. A higher awareness of nutr...

    Authors: Ji Sung Yoo, Kyu-Tae Han, Seung Hyun Chung and Eun-Cheol Park

    Citation: BMC Cancer 2019 19:16

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  35. Content type: Research article

    Metachronous cancer in patients with head and neck cancer (HNC) is common and is associated with a poor prognosis. We aimed to evaluate the incidence of metachronous cancer at different sites according to age ...

    Authors: Taro Iwatsubo, Ryu Ishihara, Toshitaka Morishima, Akira Maekawa, Kentaro Nakagawa, Masamichi Arao, Masayasu Ohmori, Hiroyoshi Iwagami, Kenshi Matsuno, Shuntaro Inoue, Hiroko Nakahira, Noriko Matsuura, Satoki Shichijo, Takashi Kanesaka, Sachiko Yamamoto, Yoji Takeuchi…

    Citation: BMC Cancer 2019 19:3

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  36. Content type: Research article

    Physical fitness and psychosocial function is often reduced in children during or shortly after cancer treatment. This study evaluates the effect of a combined physical exercise and psychosocial intervention o...

    Authors: Katja I. Braam, Elisabeth M. van Dijk-Lokkart, Gertjan J. L. Kaspers, Tim Takken, Jaap Huisman, Laurien M. Buffart, Marc B. Bierings, Johannes H. M. Merks, Marry M. van den Heuvel-Eibrink, Margreet A. Veening and Eline van Dulmen-den Broeder

    Citation: BMC Cancer 2018 18:1289

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  37. Content type: Research article

    The prevalence and distribution of histologically diagnosed breast disease are not well documented in low income countries, Uganda inclusive. Although the greater majority of breast lesions globally are benign...

    Authors: Salvatore Ssemmanda, Eric Katagirya, Phiona Bukirwa, David Alele, Robert Lukande and Samuel Kalungi

    Citation: BMC Cancer 2018 18:1285

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  38. Content type: Research article

    Few epidemiologic findings are as well established as the association between smoking and lung cancer. It is therefore somewhat surprising that there is not yet a clear consensus about the exposure-response re...

    Authors: T. Remen, J. Pintos, M. Abrahamowicz and J. Siemiatycki

    Citation: BMC Cancer 2018 18:1275

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  39. Content type: Research article

    Kaposi’s sarcoma (KS) is a multifocal angioproliferative tumor involving blood and lymphatic vessels, caused by Human Herpes Virus-8 (HHV-8). KS is an important AIDS-defining tumor with high prevalence in Sub-...

    Authors: George P. Semango, Renard M. Charles, Consolata I. Swai, Alex Mremi, Patrick Amsi, Tolbert Sonda, Elichilia R. Shao, Daudi R. Mavura, Leo A. B. Joosten, Elingarami Sauli and Mramba Nyindo

    Citation: BMC Cancer 2018 18:1258

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  40. Content type: Research article

    Diabetes mellitus (DM) is associated with poorer outcomes in some cancers. Its effect on ovarian cancer is less clear. We consider the effect of DM on overall survival (OS) and progression free survival (PFS) ...

    Authors: Setareh Akhavan, Akram Ghahghaei-Nezamabadi, Mitra Modaresgilani, Azam Sadat Mousavi, Mahdi Sepidarkish, Afsaneh Tehranian and Elahe Rezayof

    Citation: BMC Cancer 2018 18:1246

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  41. Content type: Research article

    Myeloid-derived suppressor cells (MDSCs) is a heterogeneous population of immature myeloid cells, inhibiting both the innate and adaptive immunity. Recent studies validated that MDSCs caused immune suppression...

    Authors: Lisha Ai, Shidai Mu, Yadan Wang, Huafang Wang, Li Cai, Wenzhu Li and Yu Hu

    Citation: BMC Cancer 2018 18:1220

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  42. Content type: Research article

    Colorectal cancer (CRC) remains the second most common cancer in women worldwide. Physical activity (PA) has been associated with reduced risk of CRC; however, this has been demonstrated more consistently in m...

    Authors: Sunday Oluwafemi Oyeyemi, Tonje Braaten, Idlir Licaj, Eiliv Lund and Kristin Benjaminsen Borch

    Citation: BMC Cancer 2018 18:1216

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  43. Content type: Study protocol

    Epidemiological studies and cardiovascular prevention trials have shown that low-dose aspirin can reduce colorectal cancer (CRC) incidence and mortality, including inhibition of distant metastases. Metformin h...

    Authors: Marilena Petrera, Laura Paleari, Matteo Clavarezza, Matteo Puntoni, Silvia Caviglia, Irene Maria Briata, Massimo Oppezzi, Eva Mihajlovic Mislej, Borut Stabuc, Michael Gnant, Thomas Bachleitner-Hofmann, Wilfried Roth, Dominique Scherer, Walter-E. Haefeli, Cornelia M. Ulrich and Andrea DeCensi

    Citation: BMC Cancer 2018 18:1210

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  44. Content type: Research article

    Timely assessment of cancer risk from current radiation exposure among medical radiation workers can contribute to the development of strategies to prevent excessive occupational radiation exposure. The purpos...

    Authors: Won Jin Lee, Yeongchull Choi, Seulki Ko, Eun Shil Cha, Jaeyoung Kim, Young Min Kim, Kyoung Ae Kong, Songwon Seo, Ye Jin Bang and Yae Won Ha

    Citation: BMC Cancer 2018 18:1206

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