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Epidemiology, prevention and public health

This section aims to consider publications which focus on all aspects of cancer epidemiology including risk factors for disease initiation and development, social determinants, environmental, behavioural, and occupational correlates, and the impact of health policies, practices and interventions on the community.

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  1. Content type: Research article

    The best strategy for surveillance testing in stage II and III colon cancer patients following curative treatment is unknown. Previous randomized controlled trials have suffered from design limitations and yie...

    Authors: Robert B. Hines, Md Jibanul Haque Jiban, Adrian V. Specogna, Priya Vishnubhotla, Eunkyung Lee and Shunpu Zhang

    Citation: BMC Cancer 2019 19:418

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  2. Content type: Research article

    In Ethiopia, the incidence of new cases of breast cancer is currently increasing resulting to high rates of morbidity and mortality. Breast cancer is by far the most common cancer accounting for more than one ...

    Authors: Biniyam Tefera Deressa, Nikola Cihoric, Eugenia Vlaskou Badra, Alexandros Tsikkinis and Daniel Rauch

    Citation: BMC Cancer 2019 19:393

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  3. Content type: Research article

    Effector CD8+ T cell activation and its cytotoxic function to eradicate tumor cells depend on the T cell recognition of tumor neoantigens, and are positively associated with improved survival in breast cancer. Tu...

    Authors: Lingeng Lu, Huatian Huang, Jing Zhou, Wenxue Ma, Sean Mackay and Zuoheng Wang

    Citation: BMC Cancer 2019 19:387

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  4. Content type: Research article

    Little is known about the pathway to diagnosis of lymphoma in Sub-Saharan Africa, despite the increased risk of lymphoma in people living with HIV (PLHIV). The challenges of diagnosis in this setting include d...

    Authors: Katherine Antel, Carly Levetan, Zainab Mohamed, Vernon J Louw, Jenna Oosthuizen, Gary Maartens and Estelle Verburgh

    Citation: BMC Cancer 2019 19:384

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  5. Content type: Research article

    The healthcare system (HCS) improved in Tibet Autonomous Region (TAR), China. The present study aimed to investigate whether these improvements might alter the clinicopathological characteristics of a Tibetan ...

    Authors: Yulan Zhao, Hanhuan Luo, Xintian Zhang, Tashi Bianba, Lin Li, Qian Wang, Lei Guo, Dian Wang, Yongge Ze and Shan Zheng

    Citation: BMC Cancer 2019 19:380

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  6. Content type: Research article

    Smoking is one of the well-established risk factors for gastric cancer incidence, yet whether men are more or equally susceptible to gastric cancer due to smoking compared with women is a matter of controversy...

    Authors: Wen-Ya Li, Yunan Han, Hui-Mian Xu, Zhen-Ning Wang, Ying-Ying Xu, Yong-Xi Song, Hao Xu, Song-Cheng Yin, Xing-Yu Liu and Zhi-Feng Miao

    Citation: BMC Cancer 2019 19:377

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  7. Content type: Research article

    Cervical Cancer is still a major public health challenge in low and middle-income countries. HPV testing has been an innovative approach, which was introduced in Argentina for women aged 30+ through the Jujuy ...

    Authors: Juan Gago, Melisa Paolino and Silvina Arrossi

    Citation: BMC Cancer 2019 19:367

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  8. Content type: Research article

    Phase I trials aim to identify the recommended dose for further development. Health-related quality of life (HRQoL) could be a complement to the usual National Cancer Institute Common Terminology Criteria for ...

    Authors: Frédéric Fiteni, Isabelle Le Ray, Ahmad Ousmen, Nicolas Isambert, Amélie Anota and Franck Bonnetain

    Citation: BMC Cancer 2019 19:361

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  9. Content type: Research article

    Salivary gland carcinoma ranks the sixth in head and neck cancers while it is relatively rare in its incidence. Epidemiological studies have been based mostly on institutional data, leading to selection bias i...

    Authors: Jin-Ye Fu, Chun-Xiao Wu, Shu-Kun Shen, Ying Zheng, Chen-Ping Zhang and Zhi-Yuan Zhang

    Citation: BMC Cancer 2019 19:350

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  10. Content type: Research article

    Extrahepatic cholangiocarcinoma (ECC) has become one of the most rapidly increasing malignancies in China during recent decades. The relationship between tobacco exposure and ECC epidemics is unclear; this stu...

    Authors: Lei Hou, Jingmei Jiang, Boqi Liu, Wei Han, Yanping Wu, Xiaonong Zou, Fang Xue, Yuanli Chen, Biao Zhang, Haiyu Pang, Yuyan Wang, Zixing Wang, Yaoda Hu and Junyao Li

    Citation: BMC Cancer 2019 19:348

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  11. Content type: Research article

    Incidence of renal dysfunction and risks of progression to end-stage renal disease (ESRD) were reported higher in upper urinary tract urothelial carcinoma (UTUC) than in renal cell carcinoma (RCC) patients aft...

    Authors: Sheng-Wen Niu, Peir-In Liang, Ming-Yen Lin, Shih-Meng Yeh, Yen-Yi Zhen, Yu-Han Chang, Pin-Chia Huang, Chi-Chi Hung, I-Ching Kuo, Hugo You-Hsien Lin, Mei-Chuan Kuo, Wei-Ming Li, Chun-Nung Huang, Wen-Jeng Wu, Li-Tzong Chen, Yi-Wen Chiu…

    Citation: BMC Cancer 2019 19:337

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  12. Content type: Research article

    Our aim was to determine the epidemiology and recent changes in the trends of non-functional pancreatic neuroendocrine tumours (NF-pNETs) at the population level. In addition, we explored the risk factors that...

    Authors: Junjun Wu, Chi Sun, Enliang Li, Jiakun Wang, Xianping He, Rongfa Yuan, Chenghao Yi, Wenjun Liao and Linquan Wu

    Citation: BMC Cancer 2019 19:334

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  13. Content type: Research article

    In France, a Pap test for cervical cancer screening is recommended every three years for all sexually active women aged 25 to 65 years. Modes of contraception (any or no contraception, with or without a visit to ...

    Authors: Stéphanie Mignot, Virginie Ringa, Solène Vigoureux, Marie Zins, Henri Panjo, Pierre-Jean Saulnier and Xavier Fritel

    Citation: BMC Cancer 2019 19:317

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  14. Content type: Research article

    Colorectal cancer (CRC) is the second cause of tumour mortality in Spain and Europe. To date, no studies have been conducted in Spain to evaluate the spatial and temporal distribution of the excess risk of dea...

    Authors: J. M. García-Torrecillas, M. C. Olvera-Porcel, M. Ferrer-Márquez, F. Rubio-Gil, M J. Sánchez and M. Rodríguez-Barranco

    Citation: BMC Cancer 2019 19:310

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  15. Content type: Research article

    Thyroid cancer is the most frequent endocrine neoplasia worldwide. Information from Andean countries is scarce. In Ecuador there is no reports available of the epidemiology of this type of cancer. The aim of t...

    Authors: Jorge Salazar-Vega, Esteban Ortiz-Prado, Paola Solis-Pazmino, Lenin Gómez-Barreno, Katherine Simbaña-Rivera, Aquiles R. Henriquez-Trujillo, Juan P. Brito, Theofilos Toulkeridis and Marco Coral-Almeida

    Citation: BMC Cancer 2019 19:294

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  16. Content type: Study protocol

    Human papillomavirus (HPV) vaccines are indicated for the prevention of cancers and genital warts caused by vaccine-covered HPV types. Although the standard regimen requires a two or three-dose vaccine series,...

    Authors: Yi Zeng, Anna-Barbara Moscicki, Vikrant V. Sahasrabuddhe, Francisco Garcia, Heide Woo, Chiu-Hsieh Hsu, Eva Szabo, Eileen Dimond, Susan Vanzzini, Angelica Mondragon, Valerie Butler, Hillary DeRose and H.-H. Sherry Chow

    Citation: BMC Cancer 2019 19:290

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  17. Content type: Research article

    Recently, the concept of “late presentation with viral hepatitis” was introduced to help quantify the proportion of patients missing timely diagnosis and treatment for viral hepatitis. The clinical implication...

    Authors: Dong Hyun Sinn, Danbee Kang, Minwoong Kang, Seung Woon Paik, Eliseo Guallar, Juhee Cho and Geum-Youn Gwak

    Citation: BMC Cancer 2019 19:286

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  18. Content type: Research article

    There is limited information on changes over time in carcinoid syndrome (CS) symptoms and quality of life (QoL). This study assessed change in CS symptoms and QoL in patients treated with somatostatin analogs ...

    Authors: Daniel M. Halperin, Lynn Huynh, Jennifer L. Beaumont, Beilei Cai, Rachel H. Bhak, Sahil Narkhede, Todor Totev, Mei S. Duh, Maureen P. Neary and David Cella

    Citation: BMC Cancer 2019 19:274

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  19. Content type: Research article

    Cardiovascular medications may be associated with cancer development, but little is known about their association with cancer recurrence. Medications such as statins and antihypertensives may be commonly used ...

    Authors: Erin J. A. Bowles, Onchee Yu, Rebecca Ziebell, Lu Chen, Denise M. Boudreau, Debra P. Ritzwoller, Rebecca A. Hubbard, Jennifer M. Boggs, Andrea N. Burnett-Hartman, Andrew Sterrett, Monica Fujii and Jessica Chubak

    Citation: BMC Cancer 2019 19:270

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  20. Content type: Research article

    Data from population-based cancer registries (PBCRs) are a useful resource for estimating the incidence of cancers. PBCR data is useful in the planning and implementation of cancer prevention and control strat...

    Authors: Yaw Ampem Amoako, Baffour Awuah, Rita Larsen-Reindorf, Fred Kwame Awittor, Gloria Kyem, Kwame Ofori-Boadu, Ernest Osei-Bonsu and Dennis Odai Laryea

    Citation: BMC Cancer 2019 19:267

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  21. Content type: Research article

    Although men carry a higher risk of hepatocellular carcinoma (HCC) than women, it is still controversial whether men also have a poorer postoperative prognosis. A retrospective study was conducted to evaluate ...

    Authors: Ming-Wei Lai, Yu-De Chu, Chih-Lang Lin, Rong-Nan Chien, Ta-Sen Yeh, Tai-Long Pan, Po-Yuan Ke, Kwang-Hui Lin and Chau-Ting Yeh

    Citation: BMC Cancer 2019 19:250

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  22. Content type: Research article

    Cancer indicators are essential information for cancer surveillance and cancer research strategy development. The Martinique Cancer Registry (MCR) is a population-based cancer Registry (PBCR) that has been rec...

    Authors: Clarisse Joachim, Jacqueline Veronique-Baudin, Stephen Ulric-Gervaise, Audrey Pomier, Aimée Pierre-Louis, Mylène Vestris, Jean-Luc Novella, Moustapha Drame, Jonathan Macni and Patrick Escarmant

    Citation: BMC Cancer 2019 19:239

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  23. Content type: Research article

    The purpose of the present study was to characterize the prevalence, associated factors, and to construct a nomogram for predicting bone metastasis (BM) with different histological types of lung cancer.

    Authors: Chao Zhang, Min Mao, Xu Guo, Ping Cui, Lianmin Zhang, Yao Xu, Lili Li, Xiuxin Han, Karl Peltzer, Shunbin Xiong, Vladimir P. Baklaushev, Xin Wang and Guowen Wang

    Citation: BMC Cancer 2019 19:238

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  24. Content type: Research article

    Breast cancer is the most common cancer in women worldwide, with a great diversity in outcomes among individual patients. The ability to accurately predict a breast cancer outcome is important to patients, phy...

    Authors: Minh Tung Phung, Sandar Tin Tin and J. Mark Elwood

    Citation: BMC Cancer 2019 19:230

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  25. Content type: Research article

    Despite strong evidence of benefit, breast cancer risk assessment and chemoprevention are underutilized by primary care physicians. This study evaluates the impact of an educational program on knowledge and ut...

    Authors: Siddhartha Yadav, Sarah Hartkop, Paola Yumpo Cardenas, Rand Ladkany, Alexandra Halalau, Sandor Shoichet, Michael Maddens and Dana Zakalik

    Citation: BMC Cancer 2019 19:228

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  26. Content type: Research article

    The gastric cancer incidence rate differs widely across geographical areas. In Italy, in the province of Cremona the incidence is high, compared to the national situation. For this reason a specialized populat...

    Authors: B. M. Donida, G. Tomasello, M. Ghidini, F. Buffoli, M. Grassi, W. Liguigli, G. Maglietta, L. Pergola, M. Ratti, G. Sabadini, L. Toppo, M. Ungari and R. Passalacqua

    Citation: BMC Cancer 2019 19:212

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  27. Content type: Research article

    Recurrence is not explicitly documented in cancer registry data that are widely used for research. Patterns of events after initial treatment such as oncology visits, re-operation, and receipt of subsequent ch...

    Authors: Yuan Xu, Shiying Kong, Winson Y. Cheung, Antoine Bouchard-Fortier, Joseph C. Dort, Hude Quan, Elizabeth M. Buie, Geoff McKinnon and May Lynn Quan

    Citation: BMC Cancer 2019 19:210

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  28. Content type: Research article

    The length of interval between successive childbirths (birth interval) might influence the incidence of breast cancer, either by stimulating or by inhibiting the factors that are responsible for the initiation...

    Authors: Sushmita Katuwal, Juha S. Tapanainen, Eero Pukkala and Antti Kauppila

    Citation: BMC Cancer 2019 19:199

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  29. Content type: Research article

    Philadelphia (Ph) chromosome-negative myeloproliferative neoplasms (MPNs) are a heterogeneous group of hematopoietic stem cell clonal diseases. Most patients with MPN are asymptomatic at diagnosis although som...

    Authors: Tarinee Rungjirajittranon, Weerapat Owattanapanich, Patompong Ungprasert, Noppadol Siritanaratkul and Theera Ruchutrakool

    Citation: BMC Cancer 2019 19:184

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  30. Content type: Research article

    Although rare cancers account for 27% of cancer diagnoses in the US, there is insufficient research on survivorship issues in these patients. An important issue cancer survivors face is an elevated risk of bei...

    Authors: Dianne M. Finkelstein, Nora K. Horick, Ritesh Ramchandani, Kristina L. Boyd, Huma Q. Rana and Brittany L. Bychkovsky

    Citation: BMC Cancer 2019 19:166

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  31. Content type: Research article

    The association of ABO blood groups with gastric cancer risk was proposed decades ago, but the results have been inconsistent.

    Authors: Yingying Mao, Wenjun Yang, Qi Qi, Fei Yu, Tianpei Wang, Hongfei Zhang, Juncheng Dai, Hongxia Ma, Zhibin Hu, Hongbing Shen, Gang Li and Guangfu Jin

    Citation: BMC Cancer 2019 19:164

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  32. Content type: Research article

    The aim of this study was to evaluate the prevalence of some gynecological cancer risk factors in a population of female relatives of cancer patients in Hacettepe University Oncology Hospital. Additionally, wh...

    Authors: Nooria Atta, Saadettin Kilickap, Deniz Yuce and Mutlu Hayran

    Citation: BMC Cancer 2019 19:154

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  33. Content type: Research article

    Chemotherapy-induced thrombocytopenia (CIT) is a potentially serious complication that can lead to chemotherapy dose delays, dose reductions, or discontinuation, and increases the risk of serious bleeding even...

    Authors: Derek Weycker, Mark Hatfield, Aaron Grossman, Ahuva Hanau, Alex Lonshteyn, Anjali Sharma and David Chandler

    Citation: BMC Cancer 2019 19:151

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  34. Content type: Research article

    The brain is a common site for metastasis in non-small-cell lung cancer (NSCLC). This study was designed to evaluate the relationship between the mutational of the epidermal growth factor receptor (EGFR) and o...

    Authors: Wen-Ya Li, Ting-Ting Zhao, Hui-Mian Xu, Zhen-Ning Wang, Ying-Ying Xu, Yunan Han, Yong-Xi Song, Jian-Hua Wu, Hao Xu, Song-Cheng Yin, Xing-Yu Liu and Zhi-Feng Miao

    Citation: BMC Cancer 2019 19:145

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  35. Content type: Research article

    Evidence from clinical trials suggests that the addition of bevacizumab to chemotherapy in the first-line treatment of patients with HER2-negative metastatic breast cancer improves progression-free survival (P...

    Authors: Audrey Petitjean, Jayne Smith-Palmer, William Valentine, Bertrand Tehard and Stephané Roze

    Citation: BMC Cancer 2019 19:140

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  36. Content type: Research article

    Intracranial and intraspinal tumours are the most numerous solid tumours in children. Some recently defined subtypes are relatively frequent in childhood. Many cancer registries routinely ascertain CNS tumours...

    Authors: Charles A. Stiller, Anita M. Bayne, Aruna Chakrabarty, Tom Kenny and Paul Chumas

    Citation: BMC Cancer 2019 19:139

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  37. Content type: Research article

    Considering the lack of efficient breast cancer prediction models suitable for general population screening in China. We aimed to develop a risk prediction model to identify high-risk populations, to help with...

    Authors: Lu Wang, Liyuan Liu, Zhen Lou, Lijie Ding, Hui Guan, Fei Wang, Lixiang Yu, Yujuan Xiang, Fei Zhou, Fuzhong Xue and Zhigang Yu

    Citation: BMC Cancer 2019 19:128

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  38. Content type: Research article

    The prognostic value of Ki-67 expression in colorectal cancer patients was controversial. Therefore, this meta analysis was conducted to ascertain the prognostic value of Ki-67 expression in colorectal cancer ...

    Authors: Zhao-Wen Luo, Ming-Gu Zhu, Zhi-Qiao Zhang, Feng-Jun Ye, Wen-Heng Huang and Xue-Zhang Luo

    Citation: BMC Cancer 2019 19:123

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  39. Content type: Research article

    The Swiss Federal Office of Public Health has recommended vaccination against human papillomavirus (HPV) to prevent cervical cancer since 2008. To establish monitoring of the future public health impact of vac...

    Authors: Dianne Egli-Gany, Anne Spaar Zographos, Joachim Diebold, Virginie Masserey Spicher, Brigitte Frey Tirri, Rolf Heusser, Joakim Dillner, Patrick Petignat, Roland Sahli and Nicola Low

    Citation: BMC Cancer 2019 19:111

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  40. Content type: Research article

    Breast cancer prognosis has dramatically improved over 40 years. There is, however, no proof of population ‘cure’. This research aimed to examine the pattern of long-term excess mortality due to breast cancer ...

    Authors: R. Schaffar, A. Belot, B. Rachet and L. Woods

    Citation: BMC Cancer 2019 19:107

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  41. Content type: Research article

    Epidemiological research on small cell lung cancer (SCLC) is limited and based on cancer registry data. We evaluated the feasibility and validity of using primary care electronic health records (The Health Imp...

    Authors: Lucía Cea Soriano, Jihong Zong and Luis A. García Rodríguez

    Citation: BMC Cancer 2019 19:91

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  42. Content type: Research article

    A sizeable body of evidence suggests that statins can cease breast cancer progression and prevent breast cancer recurrence. The latest studies have, however, not been supportive of such clinically beneficial e...

    Authors: Signe Borgquist, Per Broberg, Jasaman Tojjar and Håkan Olsson

    Citation: BMC Cancer 2019 19:54

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  43. Content type: Research article

    To date, no single colorectal cancer (CRC) screening strategy has been determined to be applicable worldwide. In China, a CRC screening protocol that combines double fecal immunochemical tests (FITs) and a hig...

    Authors: Shan-Rong Cai, Yan-Qin Huang, Su-Zhan Zhang, Qi-Rong Li, Xin Yuan Ma and Shu Zheng

    Citation: BMC Cancer 2019 19:47

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  44. Content type: Research article

    Transitional cell carcinoma (TCC) accounts for around 95% of bladder cancers and is the 4th most common cancer among men and the tenth most common in women, in the US. There is a constant need to clarify curre...

    Authors: Muneer J. Al-Husseini, Ahmad Kunbaz, Anas M. Saad, João Vasco Santos, Sami Salahia, Marium Iqbal and Fares Alahdab

    Citation: BMC Cancer 2019 19:46

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  45. Content type: Research article

    In Canada, clinical practice guidelines recommend breast cancer screening, but there are gaps in adherence to recommendations for screening, particularly among certain hard-to-reach populations, that may diffe...

    Authors: A. K. Lofters, M. L. McBride, D. Li, M. Whitehead, R. Moineddin, L. Jiang, E. Grunfeld and P. A. Groome

    Citation: BMC Cancer 2019 19:42

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