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Epidemiology, prevention and public health

This section aims to consider publications which focus on all aspects of cancer epidemiology including risk factors for disease initiation and development, social determinants, environmental, behavioural, and occupational correlates, and the impact of health policies, practices and interventions on the community.

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  1. Content type: Research article

    Cervical cancer ranks second among all cancers reported in Sri Lankan women. This study assessed the prevalence and type-distribution of human papillomavirus (HPV) among Sri Lankan women with invasive cervical...

    Authors: Kanishka Karunaratne, Himali Ihalagama, Saman Rohitha, Anco Molijn, Kusuma Gopala, Johannes E Schmidt, Jing Chen, Sanjoy Datta and Shailesh Mehta

    Citation: BMC Cancer 2014 14:116

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  2. Content type: Study protocol

    Prostate cancer is the most common cancer in male in most Western countries, including France. Despite a significant morbidity and mortality to a lesser extent, the etiology of prostate cancer remains largely ...

    Authors: Florence Menegaux, Antoinette Anger, Hasina Randrianasolo, Claire Mulot, Pierre Laurent-Puig, François Iborra, Jean-Pierre Bringer, Benoit Leizour, Rodolphe Thuret, Pierre-Jean Lamy, Xavier Rébillard and Brigitte Trétarre

    Citation: BMC Cancer 2014 14:106

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  3. Content type: Research article

    Increased ratio of n-3/n-6 polyunsaturated fatty acids (PUFAs) in diet or serum may have a protective effect on the risk of breast cancer (BC); however, the conclusions from prospective studies are still contr...

    Authors: Bo Yang, Xiao-Li Ren, Yuan-Qin Fu, Jin-Long Gao and Duo Li

    Citation: BMC Cancer 2014 14:105

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  4. Content type: Research article

    Obesity is associated with an increased risk of esophageal adenocarcinoma (EAC) and a decreased risk of esophageal squamous cell carcinoma (ESCC). However, little is known about the risk of EAC and ESCC relate...

    Authors: Björn Lindkvist, Dorthe Johansen, Tanja Stocks, Hans Concin, Tone Bjørge, Martin Almquist, Christel Häggström, Anders Engeland, Göran Hallmans, Gabriele Nagel, Håkan Jonsson, Randi Selmer, Hanno Ulmer, Steinar Tretli, Pär Stattin and Jonas Manjer

    Citation: BMC Cancer 2014 14:103

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  5. Content type: Research article

    Accurate indication classification is critical for obtaining unbiased estimates of colonoscopy effectiveness and quality improvement efforts, but there is a dearth of published systematic classification approa...

    Authors: Hirut Fassil, Kenneth F Adams, Sheila Weinmann, V Paul Doria-Rose, Eric Johnson, Andrew E Williams, Douglas A Corley and Chyke A Doubeni

    Citation: BMC Cancer 2014 14:95

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  6. Content type: Research article

    Although cancer survivors are known to be at greater risk of developing second primary cancer (SPC), SPC incidence estimates in France are thus far lacking. We used a multivariate approach to compute these est...

    Authors: Jérémie Jégu, Marc Colonna, Laetitia Daubisse-Marliac, Brigitte Trétarre, Olivier Ganry, Anne-Valérie Guizard, Simona Bara, Xavier Troussard, Véronique Bouvier, Anne-Sophie Woronoff and Michel Velten

    Citation: BMC Cancer 2014 14:94

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  7. Content type: Research article

    The struggle against social inequalities is a priority for many international organizations. The objective of the study was to quantify the cancer burden related to social deprivation by identifying the cancer...

    Authors: Josephine Bryere, Olivier Dejardin, Veronique Bouvier, Marc Colonna, Anne-Valérie Guizard, Xavier Troussard, Carole Pornet, Françoise Galateau-Salle, Simona Bara, Ludivine Launay, Lydia Guittet and Guy Launoy

    Citation: BMC Cancer 2014 14:87

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  8. Content type: Study protocol

    There is a need for psychosocial interventions for men with prostate cancer to promote adaptive coping with the challenges and distress associated with diagnosis, treatment and recovery. In addition, intervent...

    Authors: Addie C Wootten, Jo-Anne M Abbott, Katherine E Chisholm, David W Austin, Britt Klein, Marita P McCabe, Denny Meyer, Anthony J Costello and Declan G Murphy

    Citation: BMC Cancer 2014 14:83

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  9. Content type: Research article

    Although diagnosed less often, breast cancer in African American women (AAW) displays different characteristics compared to breast cancer in Caucasian women (CW), including earlier onset, less favorable clinic...

    Authors: Lori A Sturtz, Jen Melley, Kim Mamula, Craig D Shriver and Rachel E Ellsworth

    Citation: BMC Cancer 2014 14:62

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  10. Content type: Research article

    There is a paucity of data on familial risk of developing esophageal adenocarcinoma, gastric cardia adenocarcinoma and distal gastric adenocarcinoma from population-based studies.

    Authors: Xuejuan Jiang, Chiu-Chen Tseng, Leslie Bernstein and Anna H Wu

    Citation: BMC Cancer 2014 14:60

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  11. Content type: Study protocol

    Evidence for the carcinogenicity of shift work in humans is limited because of significant heterogeneity of the results, thus more in-depth research in needed. The Nightingale Study is a nationwide prospective...

    Authors: Anouk Pijpe, Pauline Slottje, Cres van Pelt, Floor Stehmann, Hans Kromhout, Flora E van Leeuwen, Roel CH Vermeulen and Matti A Rookus

    Citation: BMC Cancer 2014 14:47

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  12. Content type: Research article

    Perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS) are persistent environmental contaminants that affect metabolic regulation, inflammation, and other factors implicated in the development and prog...

    Authors: Kim E Innes, Jeffrey H Wimsatt, Stephanie Frisbee and Alan M Ducatman

    Citation: BMC Cancer 2014 14:45

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  13. Content type: Research article

    In the oncology setting, there has been increasing interest in evaluating treatment outcomes in terms of quality of life and patient satisfaction. The aim of our study was to investigate the determinants of pa...

    Authors: Thanh Vân France Nguyen, Amélie Anota, Anne Brédart, Alain Monnier, Jean-François Bosset and Mariette Mercier

    Citation: BMC Cancer 2014 14:42

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  14. Content type: Research article

    The Institute of Medicine (IOM) has endorsed six dimensions of patient-centredness as crucial to providing quality healthcare. These dimensions outline that care must be: 1) respectful to patients’ values, pre...

    Authors: Flora Tzelepis, Shiho K Rose, Robert W Sanson-Fisher, Tara Clinton-McHarg, Mariko L Carey and Christine L Paul

    Citation: BMC Cancer 2014 14:41

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  15. Content type: Research article

    The aim of this study was to assess the severity of pain and its impact on the quality of life (QoL) in untreated patients with head and neck squamous cell carcinoma (HNSCC).

    Authors: Karine G Oliveira, Sandra V von Zeidler, Jose RV Podestá, Agenor Sena, Evandro D Souza, Jeferson Lenzi, Nazaré S Bissoli and Sonia A Gouvea

    Citation: BMC Cancer 2014 14:39

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  16. Content type: Research article

    Higher sunlight exposure is correlated with lower incidence of breast cancer in ecological studies, but findings from prospective studies regarding the association of circulating levels of vitamin D with the r...

    Authors: Yeonju Kim, Adrian A Franke, Yurii B Shvetsov, Lynne R Wilkens, Robert V Cooney, Galina Lurie, Gertraud Maskarinec, Brenda Y Hernandez, Loïc Le Marchand, Brian E Henderson, Laurence N Kolonel and Marc T Goodman

    Citation: BMC Cancer 2014 14:29

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  17. Content type: Study protocol

    Individuals with a personal or family history of cancer, can opt for genetic counseling and DNA-testing. Approximately 25% of these individuals experience clinically relevant levels of psychosocial distress, d...

    Authors: Willem Eijzenga, Neil K Aaronson, Irma Kluijt, Grace N Sidharta, Daniela EE Hahn, Margreet GEM Ausems and Eveline MA Bleiker

    Citation: BMC Cancer 2014 14:26

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  18. Content type: Research article

    The reasons for the increasing breast cancer incidence in indigenous Māori compared to non-Māori New Zealand women are unknown. The aim of this study was to assess the association of an index of combined healt...

    Authors: Fiona McKenzie, Lis Ellison-Loschmann, Mona Jeffreys, Ridvan Firestone, Neil Pearce and Isabelle Romieu

    Citation: BMC Cancer 2014 14:12

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  19. Content type: Study protocol

    Lung cancer is the leading cause of cancer death worldwide and characterized by a poor prognosis. It has a major impact on the psychological wellbeing of patients and their partners. Recently, it has been show...

    Authors: Melanie PJ Schellekens, Desiree GM van den Hurk, Judith B Prins, Johan Molema, A Rogier T Donders, Willem H Woertman, Miep A van der Drift and Anne EM Speckens

    Citation: BMC Cancer 2014 14:3

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  20. Content type: Research article

    There is increasing ambiguity towards national mammographic screening programs due to varying publicized estimates of overdiagnosis, i.e., breast cancer that would not have been diagnosed in the women’s lifeti...

    Authors: Eiliv Lund, Nicolle Mode, Marit Waaseth and Jean-Christophe Thalabard

    Citation: BMC Cancer 2013 13:614

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  21. Content type: Research article

    Information on the underlying cause of death of cancer patients is of interest because it can be used to estimate net survival. The population-based Geneva Cancer Registry is unique because registrars are able...

    Authors: Robin Schaffar, Elisabetta Rapiti, Bernard Rachet and Laura Woods

    Citation: BMC Cancer 2013 13:609

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  22. Content type: Research article

    A pathway-based genotyping analysis suggested rs2078486 was a novel TP53 SNP, but very few studies replicate this association. TP53 rs1042522 is the most commonly studied SNP, but very few studies examined its po...

    Authors: Yanli Li, Shen-Chih Chang, Rungui Niu, Li Liu, Christina R Crabtree-Ide, Baoxing Zhao, Jianping Shi, Xiaoyou Han, Jiawei Li, Jia Su, Lin Cai, Shunzhang Yu, Zuo-Feng Zhang and Lina Mu

    Citation: BMC Cancer 2013 13:607

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  23. Content type: Research article

    Excision repair cross-complementing group 2 (ERCC2) plays important roles in the repair of DNA damage and adducts. Single nucleotide polymorphisms (SNPs) of ERCC2 gene are suspected to influence the risks of ora...

    Authors: Enjiao Zhang, Zhigang Cui, Zhongfei Xu, Weiyi Duan, Shaohui Huang, Xuexin Tan, Zhihua Yin, Changfu Sun and Li Lu

    Citation: BMC Cancer 2013 13:594

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  24. Content type: Research article

    The association of reproductive factors with hormone receptor (HR)-negative breast tumors remains uncertain.

    Authors: Rebecca Ritte, Kaja Tikk, Annekatrin Lukanova, Anne Tjønneland, Anja Olsen, Kim Overvad, Laure Dossus, Agnès Fournier, Françoise Clavel-Chapelon, Verena Grote, Heiner Boeing, Krasimira Aleksandrova, Antonia Trichopoulou, Pagona Lagiou, Dimitrios Trichopoulos, Domenico Palli…

    Citation: BMC Cancer 2013 13:584

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  25. Content type: Research article

    Owing to the high mortality and rapidly growing costs related to lung cancer, it is worth examining the health benefits of prevention for major types of lung cancer. This study attempts to quantify the quality...

    Authors: Szu-Chun Yang, Wu-Wei Lai, Wu-Chou Su, Shang-Yin Wu, Helen HW Chen, Yi-Lin Wu, Mei-Chuan Hung and Jung-Der Wang

    Citation: BMC Cancer 2013 13:579

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  26. Content type: Research article

    Lifestyle factors, including food and nutrition, physical activity, body composition and reproductive factors, and single nucleotide polymorphisms (SNPs) are associated with breast cancer risk, but few studies...

    Authors: Taeko Mizoo, Naruto Taira, Keiko Nishiyama, Tomohiro Nogami, Takayuki Iwamoto, Takayuki Motoki, Tadahiko Shien, Junji Matsuoka, Hiroyoshi Doihara, Setsuko Ishihara, Hiroshi Kawai, Kensuke Kawasaki, Youichi Ishibe, Yutaka Ogasawara, Yoshifumi Komoike and Shinichiro Miyoshi

    Citation: BMC Cancer 2013 13:565

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  27. Content type: Research article

    The aim of this study was to evaluate the role of family history of cancer and personal history of other medical conditions in the aetiology of the oral cavity cancer in France.

    Authors: Loredana Radoï, Sophie Paget-Bailly, Florence Guida, Diane Cyr, Gwenn Menvielle, Annie Schmaus, Matthieu Carton, Sylvie Cénée, Marie Sanchez, Anne-Valérie Guizard, Brigitte Trétarre, Isabelle Stücker and Danièle Luce

    Citation: BMC Cancer 2013 13:560

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  28. Content type: Research article

    A diagnosis of prostate cancer leads to emotional distress and anxiety, prompting calls for rapid diagnostic pathways. Nevertheless, it remains unclear what impact time between diagnosis and surgery has upon p...

    Authors: Maria Theresa Redaniel, Richard M Martin, David Gillatt, Julia Wade and Mona Jeffreys

    Citation: BMC Cancer 2013 13:559

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  29. Content type: Research article

    We have previously shown that a functional polymorphism of the UGT2B15 gene (rs1902023) was associated with increased risk of prostate cancer (PC). Novel functional polymorphisms of the UGT2B17 and UGT2B15 genes ...

    Authors: Adriana C Vidal, Cocoa Tucker, Joellen M Schildkraut, Ricardo M Richardson, Megan McPhail, Stephen J Freedland, Cathrine Hoyo and Delores J Grant

    Citation: BMC Cancer 2013 13:556

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  30. Content type: Research article

    Data on the current burden of adenocarcinoma (ADC) and histology-specific human papillomavirus (HPV) type distribution are relevant to predict the future impact of prophylactic HPV vaccines.

    Authors: Jeanne M Pimenta, Claudia Galindo, David Jenkins and Sylvia M Taylor

    Citation: BMC Cancer 2013 13:553

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  31. Content type: Research article

    Esophageal cancer (EC) is a frequently occurring cancer with poor prognosis despite combined therapeutic strategies. Many biomarkers have been proposed as predictors of adverse events. We sought to assess the ...

    Authors: Meilan Chen, Jizheng Huang, Zhenli Zhu, Jun Zhang and Ke Li

    Citation: BMC Cancer 2013 13:539

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    The Erratum to this article has been published in BMC Cancer 2014 14:892

  32. Content type: Research article

    National organizations recommend screening for hepatitis B virus (HBV) before chemotherapy but differ regarding which patients should be screened. We aimed to determine contemporary screening rates at a cancer...

    Authors: Jessica P Hwang, Michael J Fisch, Anna S-F Lok, Hong Zhang, John M Vierling and Maria E Suarez-Almazor

    Citation: BMC Cancer 2013 13:534

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  33. Content type: Research article

    A total of 2,514,346 metric tons (Mt) of asbestos were imported into Spain from 1906 until the ban on asbestos in 2002. Our objective was to study pleural cancer mortality trends as an indicator of mesotheliom...

    Authors: Gonzalo López-Abente, Montserrat García-Gómez, Alfredo Menéndez-Navarro, Pablo Fernández-Navarro, Rebeca Ramis, Javier García-Pérez, Marta Cervantes, Eva Ferreras, María Jiménez-Muñoz and Roberto Pastor-Barriuso

    Citation: BMC Cancer 2013 13:528

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  34. Content type: Research article

    Given their frequency of occurrence in the United States, cancer and heart disease often coexist. For patients requiring open-heart surgery, this raises concern that the use of cardiopulmonary bypass (CPB) may...

    Authors: Cathy Anne Pinto, Stephen Marcella, David A August, Bart Holland, John B Kostis and Kitaw Demissie

    Citation: BMC Cancer 2013 13:519

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  35. Content type: Research article

    One in eight women will develop breast cancer in her lifetime. The best-known awareness event is breast cancer awareness month (BCAM). BCAM month outreach efforts have been associated with increased media cove...

    Authors: Rosemary Thackeray, Scott H Burton, Christophe Giraud-Carrier, Stephen Rollins and Catherine R Draper

    Citation: BMC Cancer 2013 13:508

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  36. Content type: Research article

    Bone mineral density (BMD) and lean mass (LM) may both decrease in breast cancer survivors, thereby increasing risk of falls and fractures. Research is needed to determine whether lean mass (LM) and fat mass (...

    Authors: Stephanie M George, Anne McTiernan, Adriana Villaseñor, Catherine M Alfano, Melinda L Irwin, Marian L Neuhouser, Richard N Baumgartner, Kathy B Baumgartner, Leslie Bernstein, Ashley W Smith and Rachel Ballard-Barbash

    Citation: BMC Cancer 2013 13:497

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  37. Content type: Research article

    Triple-negative breast cancer (TNBC) remains a challenging topic for clinical oncologists. This study sought to evaluate TNBC versus other breast cancer subtypes with respect to survival parameters. We evaluat...

    Authors: Lukas Schwentner, Achim Wöckel, Jochem König, Wolfgang Janni, Florian Ebner, Maria Blettner, Rolf Kreienberg and Reyn Van Ewijk

    Citation: BMC Cancer 2013 13:487

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  38. Content type: Study protocol

    Lung cancer is the leading cause of cancer death in North America and Western Europe. Patients with lung cancer in general have reduced physical capacity, functional capacity, poor quality of life and increase...

    Authors: Morten Quist, Seppo W Langer, Mikael Rørth, Karl Bang Christensen and Lis Adamsen

    Citation: BMC Cancer 2013 13:477

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  39. Content type: Research article

    Obesity has been shown to be inversely associated with breast cancer risk in premenopausal women, while increasing risk in postmenopausal women. However, the current evidence is largely based on studies in Cau...

    Authors: Elisa V Bandera, Urmila Chandran, Gary Zirpoli, Zhihong Gong, Susan E McCann, Chi-Chen Hong, Gregory Ciupak, Karen Pawlish and Christine B Ambrosone

    Citation: BMC Cancer 2013 13:475

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  40. Content type: Research article

    Knowledge about tumour gene mutation status is essential for the treatment of increasing numbers of cancer patients, and testing quality has a major impact on treatment response and cost. In 2012, 4,629 tests ...

    Authors: Jean-François Emile, Julie Tisserand, Loic Bergougnoux, Frédérique Nowak, Gladwys Faucher, Sylvie Surel, Aude Lamy, Delphine Lecorre, Zofia Helias-Rodzewicz, Paul Hofman, Jean-Christophe Sabourin and Pierre Laurent-Puig

    Citation: BMC Cancer 2013 13:472

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  41. Content type: Research article

    Follow-up rate after a fecal occult blood test (FOBT) is low worldwide. In order to increase the follow-up rate, segmentation of the target population has been proposed as a promising strategy, because an inte...

    Authors: Yoshiki Ishikawa, Ying-Fang Zheng, Hiromu Nishiuchi, Takeo Suda, Tadahiko Hasumi and Hiroshi Saito

    Citation: BMC Cancer 2013 13:470

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  42. Content type: Research article

    Cancer is a serious health issue in China, but accurate national counts for cancer incidence are not currently available. Knowledge of the cancer burden is necessary for national cancer control planning. In th...

    Authors: Wanqing Chen, Bruce K Armstrong, Rongshou Zheng, Siwei Zhang, Xueqin Yu and Mark Clements

    Citation: BMC Cancer 2013 13:458

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  43. Content type: Research article

    Racial disparities in breast cancer survival have been well documented. This study examines the association of race/ethnicity and socioeconomic status (SES) on breast cancer-specific mortality in a large popul...

    Authors: Carol A Parise and Vincent Caggiano

    Citation: BMC Cancer 2013 13:449

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  44. Content type: Study protocol

    Patients with acute leukemia experience a substantial symptom burden and are at risk of developing infections throughout the course of repeated cycles of intensive chemotherapy. Physical activity in recent yea...

    Authors: Mary Jarden, Tom Møller, Lars Kjeldsen, Henrik Birgens, Jesper Frank Christensen, Karl Bang Christensen, Finn Diderichsen, Carsten Hendriksen and Lis Adamsen

    Citation: BMC Cancer 2013 13:446

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  45. Content type: Research article

    Breast cancer incidence is increasing. The survival rate varies and is longer in high-income countries. In Brazil, lower-income populations rely on the Unified Public Health System (Sistema Único de Saude, SUS...

    Authors: Débora Balabram, Cassio M Turra and Helenice Gobbi

    Citation: BMC Cancer 2013 13:434

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