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Epidemiology, prevention and public health

This section aims to consider publications which focus on all aspects of cancer epidemiology including risk factors for disease initiation and development, social determinants, environmental, behavioural, and occupational correlates, and the impact of health policies, practices and interventions on the community.

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  1. Small soft tissue masses are often falsely assumed to be benign and resected with failure to achieve tumor-free margins. Therefore, this study retrospectively investigated the distribution of histopathologic d...

    Authors: Felix G. Gassert, Florian T. Gassert, Katja Specht, Carolin Knebel, Ulrich Lenze, Marcus R. Makowski, Rüdiger von Eisenhart-Rothe, Alexandra S. Gersing and Klaus Woertler

    Citation: BMC Cancer 2021 21:93

    Content type: Research article

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  2. A high incidence of upper urinary tract urothelial carcinoma has been reported in the southwestern area of Taiwan, where arsenic water contamination was considered the main cause. However, there is no definite...

    Authors: Che-Wei Chang, Chien-Hui Ou, Chih-Chin Yu, Chi-Wen Lo, Chung-You Tsai, Pai-Yu Cheng, Yung-Tai Chen, Hsu-Che Huang, Chia-Chang Wu, Ching-Chia Li and Hsiang-Ying Lee

    Citation: BMC Cancer 2021 21:80

    Content type: Research article

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  3. Breast cancer is the second most common causes of women’s death, worldwide. Data on risk factors associated with female breast cancer in the Afghan population is very limited. The aim of our study was to ident...

    Authors: Zekrullah Baset, Jamshid Abdul-Ghafar, Yasmin Nadeem Parpio and Ahmed Maseh Haidary

    Citation: BMC Cancer 2021 21:71

    Content type: Research article

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  4. Use of statins is associated with a reduced risk of hepatocellular carcinoma (HCC). However, the effect of statin use on HCC recurrence is unclear. This study aimed to evaluate the effect of statin use on recu...

    Authors: Shih-Yu Yang, Chih-Chi Wang, Kuang-Den Chen, Yueh-Wei Liu, Chih-Che Lin, Ching-Hui Chuang, Yu-Chieh Tsai, Chih-Chien Yao, Yi-Hao Yen, Chang-Chun Hsiao, Tsung-Hui Hu and Ming-Chao Tsai

    Citation: BMC Cancer 2021 21:70

    Content type: Research article

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  5. In contrast to the rapid increase in thyroid cancer incidence, the mortality has remained low and stable over the last decades. In Ecuador, however, thyroid cancer mortality has increased. The objective of thi...

    Authors: Paola Solis-Pazmino, Jorge Salazar-Vega, Eddy Lincango-Naranjo, Cristhian Garcia, Gabriela Jaramillo Koupermann, Esteban Ortiz-Prado, Tannya Ledesma, Tatiana Rojas, Benjamin Alvarado-Mafla, Cesar Carcamo, Oscar J. Ponce and Juan P. Brito

    Citation: BMC Cancer 2021 21:42

    Content type: Research article

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  6. The Oral Care BC-trial reported that professional oral care (POC) reduces the incidence and severity of oral mucositis in patients receiving everolimus (EVE) and exemestane (EXE). However, the effect of POC on...

    Authors: Katsuhiko Nakatsukasa, Naoki Niikura, Kosuke Kashiwabara, Takeshi Amemiya, Ken-ichi Watanabe, Hironobu Hata, Yuichiro Kikawa, Naoki Taniike, Takashi Yamanaka, Sachiyo Mitsunaga, Kazuhiko Nakagami, Moriyasu Adachi, Naoto Kondo, Yasuyuki Shibuya, Naoki Hayashi, Mariko Naito…

    Citation: BMC Cancer 2021 21:34

    Content type: Research article

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  7. In Mainland China, advance directives (ADs) and end-of-life care for patients with tumours, especially patients with brain tumours who may have lost consciousness or the ability to speak at the early stage of ...

    Authors: Yixin Wang, Yongkang Zhang, Yang Hong, Ping Zeng, Zongtao Hu, Xiuli Xu and Hongzhi Wang

    Citation: BMC Cancer 2021 21:25

    Content type: Research article

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  8. Chronic obstructive pulmonary disease (COPD) and lung cancer are associated diseases. COPD is underdiagnosed and thus undertreated, but there is limited data on COPD diagnosis in the setting of lung cancer. We...

    Authors: Sophie Corriveau, Gregory R. Pond, Grace H. Tang and John R. Goffin

    Citation: BMC Cancer 2021 21:14

    Content type: Research article

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  9. To investigate the clinicopathological characteristics of head and neck small cell carcinoma (H&NSmCC) and identify prognostic factors on the basis of the Surveillance, Epidemiology and End Results (SEER) data...

    Authors: Chen-xi Yu, Feiluore Yibulayin, Lei Feng, Meng Wang, Meng-meng Lu, Yuan Luo, Hui Liu, Zhi-cheng Yang and Alimujiang Wushou

    Citation: BMC Cancer 2020 20:1208

    Content type: Research article

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  10. Due to the increased risk of viral infection and the severe shortage of medical resources during the pandemic of COVID-19, most hospitals in the epidemic areas significantly reduced non-emergency admissions an...

    Authors: Songxiao Xu, Xiangdong Cheng, Zhiwen Pan, Qian Song, Yihong Wang, Juan Xiong, Yongyi Chen, Fan Fan, Jing Zhu, Wanying Wu, Xueying Deng, Yanpin Yu, Xiaohong Xu, Wenhu Chen, Tao Zhu, Yang Yu…

    Citation: BMC Cancer 2020 20:1194

    Content type: Research article

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  11. Organized breast and cervical cancer screening programme could only provide services at no cost for a fraction of socioeconomic-deprived women in China and other low-resource countries, however, little evidenc...

    Authors: Heling Bao, Limin Wang, Matthew Brown, Mei Zhang, Katherine Hunt, Jiangli Di, Zhenping Zhao, Shu Cong, Jing Fan, Liwen Fang and Linhong Wang

    Citation: BMC Cancer 2020 20:1191

    Content type: Research article

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  12. Tumor micro-angiogenesis and lymphangiogenesis are effective prognostic predictors in many solid malignancies. However, its role on Xp11.2 translocation RCC has not been fully elucidated. Herein, we purposed t...

    Authors: Wenliang Ma, Jun Yang, Ning Liu, Xiaohong Pu, Feng Qu, Linfeng Xu, Xiaozhi Zhao, Xiaogong Li, Gutian Zhang, Hongqian Guo, Dongmei Li and Weidong Gan

    Citation: BMC Cancer 2020 20:1182

    Content type: Research article

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  13. Breast cancer (BC) is the most common malignancy in Latin American women, but with a wide variability with respect to their mortality. This study aims to estimate the mortality rates from BC in Peruvian women ...

    Authors: J. Smith Torres-Roman, Jose Fabian Martinez-Herrera, Greta Carioli, Jorge Ybaseta-Medina, Bryan Valcarcel, Joseph A. Pinto, Alfredo Aguilar, Katherine A. McGlynn and Carlo La Vecchia

    Citation: BMC Cancer 2020 20:1173

    Content type: Research article

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  14. The most common gender-specific malignancies are cancers of the breast and the prostate. In developing countries, cancer screening of all at risk is impractical because of healthcare resource limitations. Thus...

    Authors: Mahdieh Montazeri, Benyamin Hoseini, Neda Firouraghi, Fatemeh Kiani, Hosein Raouf-Mobini, Adele Biabangard, Ali Dadashi, Vahideh Zolfaghari, Leila Ahmadian, Saeid Eslami, Robert Bergquist, Nasser Bagheri and Behzad Kiani

    Citation: BMC Cancer 2020 20:1170

    Content type: Research article

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  15. Competing risk method has not been used in a large-scale prospective study to investigate whether increased levels of high-sensitivity C-reactive protein (hs-CRP) elevate the risk of primary liver cancer (PLC)...

    Authors: Sarah Tan Siyin, Tong Liu, Wenqiang Li, Nan Yao, Guoshuai Xu, Jun Qu and Yajun Chen

    Citation: BMC Cancer 2020 20:1168

    Content type: Research article

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  16. Patients with relapsed or refractory peripheral T-cell lymphoma (R/R PTCL) treated with pralatrexate have previously shown superior overall survival (OS) compared to those who underwent conventional chemothera...

    Authors: Seonyoung Park, Ah-Young Kim, Hyeonseok Cho, Deborah Baik, Hankil Lee, Sunghwa Cho and Hye-Young Kang

    Citation: BMC Cancer 2020 20:1157

    Content type: Research article

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  17. Women with an advantaged socioeconomic position (SEP) have a higher risk of developing breast cancer (BC). The reasons for this association do not seem to be limited to reproductive factors and remain to be un...

    Authors: Eloïse Berger, Noële Maitre, Francesca Romana Mancini, Laura Baglietto, Vittorio Perduca, Hélène Colineaux, Sabina Sieri, Salvatore Panico, Carlotta Sacerdote, Rosario Tumino, Paolo Vineis, Marie-Christine Boutron-Ruault, Gianluca Severi, Raphaële Castagné and Cyrille Delpierre

    Citation: BMC Cancer 2020 20:1138

    Content type: Research article

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  18. While immune-checkpoint inhibitors (ICIs) have transformed the field of oncology for advanced-stage cancers, they can lead to serious immune toxicities. Several systematic reviews have evaluated the risk of im...

    Authors: Zahra Karimian, Sandra Mavoungou, Joe-Elie Salem, Florence Tubach and Agnès Dechartres

    Citation: BMC Cancer 2020 20:1128

    Content type: Research article

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  19. People are at a high risk of gastric cancer if their first-degree relatives suffered from atrophic gastritis (AG), intestinal metaplasia (IM), intraepithelial neoplasia (IEN), dysplasia (DYS), or gastric cance...

    Authors: Rui Wu, Cheng Yang, Lin Ji, Zhi-Ning Fan, Yu-Wen Tao and Qiang Zhan

    Citation: BMC Cancer 2020 20:1110

    Content type: Research article

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  20. The worldwide prevalence and incidence of neuroendocrine neoplasms (NEN) have been increasing recently, although few studies have analyzed data on the current situation of NENs in Japan. Here, the Japan Neuroe...

    Authors: Toshihiko Masui, Tetsuhide Ito, Izumi Komoto and Shinji Uemoto

    Citation: BMC Cancer 2020 20:1104

    Content type: Research article

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  21. Tumour subtype has a significant effect on bone metastasis in breast cancer, but population-based estimates of the prognosis of patients with bone metastases at breast cancer diagnosis are lacking. The aim of ...

    Authors: Xiao Li, Xiaoli Zhang, Jie Liu and Yinzhong Shen

    Citation: BMC Cancer 2020 20:1102

    Content type: Research article

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  22. Follow-up after curative surgery is increasingly recognized as an important component of breast cancer care. Although current guideline regulates the follow-ups, there are no relevant studies on the adherence ...

    Authors: Ran Feng, Jingfeng Jing, Xiaojun Zhang, Ming Li and Jinnan Gao

    Citation: BMC Cancer 2020 20:1098

    Content type: Research article

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  23. Cancer is widely recognized as a global public health problem. Breast, prostate, and cervical cancer are among the most frequent types in developing countries. Assessing their incidence and mortality by region...

    Authors: Juliana Alexandra Hernández Vargas, Paula Ximena Ramírez Barbosa, Ana Milena Gil Quijano, Ana María Valbuena, Lizbeth Acuña and Jaime Alberto González

    Citation: BMC Cancer 2020 20:1097

    Content type: Research article

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  24. The incidence of thyroid cancer (TC) has increased rapidly over the past few decades in Korea. This study investigated whether the TC epidemic has been driven by overdiagnosis.

    Authors: Hee-Yeon Kang, Ikhan Kim, Yeon-Yong Kim, Jinwook Bahk and Young-Ho Khang

    Citation: BMC Cancer 2020 20:1096

    Content type: Research article

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  25. Tools based on diagnostic prediction models are available to help general practitioners (GP) diagnose colorectal cancer. It is unclear how well they perform and whether they lead to increased or quicker diagno...

    Authors: Bogdan Grigore, Ruth Lewis, Jaime Peters, Sophie Robinson and Christopher J. Hyde

    Citation: BMC Cancer 2020 20:1084

    Content type: Research article

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  26. A secondary malignancy is the most serious complication in lung cancer (LC) survivors. This study aimed to evaluate the clinicopathological features, predictable risk factors and survival of patients with LC w...

    Authors: Huabin Wang, Yin Yin, Ru Wang, Junbin Huang, Hongman Xue, Yucai Cheng, Lidan Zhang and Chun Chen

    Citation: BMC Cancer 2020 20:1081

    Content type: Research article

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  27. In recent years, the identification of genetic and phenotypic biomarkers of cancer for prevention, early diagnosis and patient stratification has been a main objective of research in the field. Different multi...

    Authors: J. C. Triviño, A. Ceba, E. Rubio-Solsona, D. Serra, I. Sanchez-Guiu, G. Ribas, R. Rosa, M. Cabo, L. Bernad, G. Pita, A. Gonzalez-Neira, G. Legarda, J. L. Diaz, A. García-Vigara, A. Martínez-Aspas, M. Escrig…

    Citation: BMC Cancer 2020 20:1079

    Content type: Research article

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  28. In low-income countries breast cancer awareness (BCA) is essential to reduce the proportion of advanced stage presentations of breast cancer. There is a lack of studies using multivariable techniques to explor...

    Authors: Rukaiya Malik, Numa Vera, Chandra Dayal, Abhay Choudhari, Jyotishna Mudaliar, Amanda Noovao Hill, Ilisapeci Kubuabola and Ronny Gunnarsson

    Citation: BMC Cancer 2020 20:1078

    Content type: Research article

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  29. The purpose of this study was to assess trends in incidence and presentation of colorectal cancer (CRC) over a period of 37 years in a stable population in Mid-Norway. Secondarily, we wanted to predict the fut...

    Authors: Øystein Høydahl, Tom-Harald Edna, Athanasios Xanthoulis, Stian Lydersen and Birger Henning Endreseth

    Citation: BMC Cancer 2020 20:1077

    Content type: Research article

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  30. There is uncertainty about the effectiveness of clinical breast examination (CBE) and conflicting recommendations regarding its usefulness as a screening tool for breast cancer. This paper provides an overview...

    Authors: Tran Thu Ngan, Nga T. Q. Nguyen, Hoang Van Minh, Michael Donnelly and Ciaran O’Neill

    Citation: BMC Cancer 2020 20:1070

    Content type: Research article

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  31. Heterogeneity of metastatic renal cell carcinoma (RCC) constraints accurate prognosis prediction of the tumor. We therefore aimed at developing a novel nomogram for accurate prediction of overall survival (OS)...

    Authors: Wenwen Zheng, Weiwei Zhu, Shengqiang Yu, Kangqi Li, Yuexia Ding, Qingna Wu, Qiling Tang, Quan Zhao, Congxiao Lu and Chenyu Guo

    Citation: BMC Cancer 2020 20:1066

    Content type: Research article

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  32. In general, human papillomavirus (HPV) vaccines have demonstrated efficacy in young women worldwide, but there is limited evidence on the efficacy of the quadrivalent HPV6/11/16/18 vaccine in adult women and n...

    Authors: Tetsuji Kurokawa, Makoto Yamamoto, Toshimichi Onuma, Hideaki Tsuyoshi, Akiko Shinagawa, Yoko Chino and Yoshio Yoshida

    Citation: BMC Cancer 2020 20:1056

    Content type: Study protocol

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  33. The incidence and mortality rates of colorectal cancer (CRC) continue to increase worldwide. Therefore, new preventive strategies are needed to lower the burden of this disease. Previous studies reported that ...

    Authors: Takuma Higurashi, Jun Arimoto, Keiichi Ashikari, Tomohiro Takatsu, Noboru Misawa, Tsutomu Yoshihara, Tetsuya Matsuura, Akiko Fuyuki, Hidenori Ohkubo and Atsushi Nakajima

    Citation: BMC Cancer 2020 20:1043

    Content type: Study protocol

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  34. The COVID-19 pandemic is predicted to significantly affect patients with lung cancer, owing to its rapid progression and high mortality. Studies on lung cancer diagnosis and treatment during an epidemic are la...

    Authors: Ji Young Park, Ye Jin Lee, Taehee Kim, Chang Youl Lee, Hwan Il Kim, Joo-Hee Kim, Sunghoon Park, Yong Il Hwang, Ki-Suck Jung and Seung Hun Jang

    Citation: BMC Cancer 2020 20:1040

    Content type: Research article

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  35. The distress thermometer (DT) is an effective tool for identifying distress among cancer patients worldwide. However, DT has not been studied in Egyptian patients. We aimed to study the prevalence of distress ...

    Authors: Nashwa Abd El-Aziz, Salah Khallaf, Waleed Abozaid, Ghada Elgohary, Ola Abd El-Fattah, Mai Alhawari, Safaa Khaled, Azza AbdelHaffez, Ehab Kamel and Sherif Mohamed

    Citation: BMC Cancer 2020 20:1033

    Content type: Research article

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  36. Studies evaluating health information needs in colorectal cancer (CRC) lack specificity in terms of study samples involving patients. We assessed how health information needs of individuals with CRC are met ac...

    Authors: Hallie Dau, Abdollah Safari, Khalid Saad El Din, Helen McTaggart-Cowan, Jonathan M. Loree, Sharlene Gill and Mary A. De Vera

    Citation: BMC Cancer 2020 20:1031

    Content type: Research article

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  37. About 85% of breast cancer patients attending Komfo Anokye Teaching Hospital (KATH), Ghana, present with stage III/IV disease. In spite of great investments into the early diagnosis and management of breast ca...

    Authors: Anita Eseenam Agbeko, Joshua Arthur, Jonathan Bayuo, Basil Benduri Kaburi and Ishmael Kyei

    Citation: BMC Cancer 2020 20:1011

    Content type: Research article

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  38. Treatment with ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) is a well-established therapy for advanced Hodgkin’s lymphoma (HL). However, the recently completed ECHELON-1 trial showed potential n...

    Authors: A. J. N. Raymakers, S. Costa, D. Cameron and D. A. Regier

    Citation: BMC Cancer 2020 20:992

    Content type: Research article

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  39. In this study, we analyze the cost-effectiveness of fruquintinib as third-line treatment for patients with metastatic colorectal cancer in China, especially after a recent price drop suggested by the National ...

    Authors: Zhi Peng, Xingduo Hou, Yangmu Huang, Tong Xie and Xinyang Hua

    Citation: BMC Cancer 2020 20:990

    Content type: Research article

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  40. The aim was to estimate the risk of subsequent extra-cervical Human Papillomavirus (HPV) related cancer in patients surgically treated for high grade cervical intraepithelial neoplasia (CIN 2–3). This is the f...

    Authors: Mario Preti, Stefano Rosso, Leonardo Micheletti, Carola Libero, Irene Sobrato, Livia Giordano, Paola Busso, Niccolò Gallio, Stefano Cosma, Federica Bevilacqua and Chiara Benedetto

    Citation: BMC Cancer 2020 20:972

    Content type: Research article

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  41. Malignant tumours of the temporomandibular joint (MTTMJ) are extremely rare. Studies describing its unique epidemiology, clinicopathological features, treatment and prognosis comprehensively are limited. To ad...

    Authors: Feiluore Yibulayin, Chen-xi Yu, Lei Feng, Meng Wang, Meng-meng Lu, Yuan Luo, Hui Liu, Zhi-cheng Yang and Alimujiang Wushou

    Citation: BMC Cancer 2020 20:967

    Content type: Research article

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  42. Risk-based breast cancer screening may improve the benefit-harm ratio of screening by tailoring policy to a woman’s personal breast cancer risk. This study aims to explore Dutch women’s preferences regarding t...

    Authors: Linda Rainey, Daniëlle van der Waal and Mireille J. M. Broeders

    Citation: BMC Cancer 2020 20:965

    Content type: Research article

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  43. The literature suggests an increased risk between anthropometrics including higher body mass index and lymphoma incidence; however, the association with physical activity remains unclear. A systematic review/m...

    Authors: Gwynivere A. Davies, Christopher Strader, Richa Chibbar, Stefania Papatheodorou and Adam A. Dmytriw

    Citation: BMC Cancer 2020 20:962

    Content type: Research article

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  44. Cervical cancer is the most common cancer among women in Sub-Saharan countries, including Tanzania. While early detection and diagnosis are available in some parts of this large country, radiotherapy has been ...

    Authors: Mariah P. Gesink, Robert M. Chamberlain, Julius Mwaiselage, Crispin Kahesa, Kahima Jackson, William Mueller, Jane L. Meza and Amr S. Soliman

    Citation: BMC Cancer 2020 20:939

    Content type: Research article

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  45. Bladder cancer (BC) is the 9th most common cancer worldwide, but little progress has been made in improving patient outcomes over the last 25 years. The King’s Health Partners (KHP) BC biobank was established ...

    Authors: Pinky Kotecha, Charlotte L. Moss, Deborah Enting, Cheryl Gillett, Magdalene Joseph, Debra Josephs, Sarah Rudman, Simon Hughes, Fidelma Cahill, Harriet Wylie, Anna Haire, James Rosekilly, Muhammad Shamin Khan, Rajesh Nair, Ramesh Thurairaja, Sachin Malde…

    Citation: BMC Cancer 2020 20:920

    Content type: Database

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