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Epidemiology, prevention and public health

This section aims to consider publications which focus on all aspects of cancer epidemiology including risk factors for disease initiation and development, social determinants, environmental, behavioural, and occupational correlates, and the impact of health policies, practices and interventions on the community.

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  1. An estimated 40% of cancer cases in the UK in 2015 were attributable to cancer risk behaviours. Tobacco smoking, alcohol consumption, obesity, and unprotected sexual intercourse are known causes of cancer and ...

    Authors: Caroline Wright, Jon Heron, Ruth Kipping, Matthew Hickman, Rona Campbell and Richard M. Martin

    Citation: BMC Cancer 2021 21:365

    Content type: Research article

    Published on:

  2. The World Health Organisation (WHO) calls for the elimination of cervical cancer (CC) as a public health issue. To achieve elimination, efforts must be aligned and accelerated. Women living with HIV (WLWH) hav...

    Authors: Anna Tisler, Sven Erik Ojavee, Piret Veerus, Pilleriin Soodla and Anneli Uusküla

    Citation: BMC Cancer 2021 21:350

    Content type: Research article

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  3. Selection of high-risk subjects for endoscopic screening of esophageal squamous cell carcinoma (ESCC) lacks individual predictive tools based on environmental risk factors.

    Authors: Xiaorong Yang, Chen Suo, Tongchao Zhang, Xiaolin Yin, Jinyu Man, Ziyu Yuan, Hui Chen, Jingru Yu, Li Jin, Xingdong Chen, Ming Lu and Weimin Ye

    Citation: BMC Cancer 2021 21:343

    Content type: Research article

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  4. Hormone replacement therapy (HRT) is widely used and has proven benefits for women with menopausal symptoms. An increasing number of women with cancer experience menopausal symptoms but the safety of HRT use i...

    Authors: Úna McMenamin, Blánaid Hicks, Carmel Hughes, Peter Murchie, Julia Hippisley-Cox, Tom Ranger, Carol Coupland and Chris Cardwell

    Citation: BMC Cancer 2021 21:313

    Content type: Study protocol

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  5. Hepatocellular carcinoma (HCC) is the most frequent primary invasive cancer of the liver. During the last decade, the epidemiology of HCC has been continuously changing in developed countries, due to more effe...

    Authors: Walter Mazzucco, Francesco Vitale, Sergio Mazzola, Rosalba Amodio, Maurizio Zarcone, Davide Alba, Claudia Marotta, Rosanna Cusimano and Claudia Allemani

    Citation: BMC Cancer 2021 21:307

    Content type: Research article

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  6. Because birth size appears to be positively associated with breast cancer risk, we have studied whether this risk may differ according to molecular breast cancer subtypes.

    Authors: Marie S. Sandvei, Signe Opdahl, Marit Valla, Pagona Lagiou, Ellen Veronika Vesterfjell, Tor Vikan Rise, Tina Syvertsen Overrein, Anette H. Skjervold, Monica J. Engstrøm, Anna M. Bofin and Lars J. Vatten

    Citation: BMC Cancer 2021 21:299

    Content type: Research article

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  7. Thymic tumors are unusual neoplasms, representing 0.2 to 1.5% of tumors in humans, but correspond to 20% of mediastinal tumors and 50% of those that occur in the anterior mediastinum. They tend to appear aroun...

    Authors: Diego F. Scarpetta-Gonzalez, Eliana Isabel Morales, Luz Fernanda Sua, Mauricio Velásquez, Saveria Sangiovanni and Liliana Fernández-Trujillo

    Citation: BMC Cancer 2021 21:279

    Content type: Research article

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  8. Alcohol consumption is a major risk factor for esophageal cancer; however, a high incidence of esophageal cancer is observed particularly among Eastern Asians, although they consume relatively less alcohol, pr...

    Authors: Chang Kyun Choi, Jungho Yang, Sun-Seog Kweon, Sang-Hee Cho, Hye-Yeon Kim, Eun Myung and Min-Ho Shin

    Citation: BMC Cancer 2021 21:254

    Content type: Research article

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  9. Liver metastasis is a significant adverse predictor of overall survival (OS) among breast cancer patients. The purpose of this study was to determine the risk and prognostic factors of breast cancer with liver...

    Authors: Lei Ji, Lei Cheng, Xiuzhi Zhu, Yu Gao, Lei Fan and Zhonghua Wang

    Citation: BMC Cancer 2021 21:238

    Content type: Research article

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  10. Taking patient centeredness into account is important in healthcare. The European Cancer Consumer Quality Index (ECCQI) is a validated tool for international benchmarking of patient experiences and satisfaction.

    Authors: A. Wind, E. D. Hartman, R. R. J. P. Van Eekeren, R. P. W. F. Wijn, J. Halámková, J. Mattson, S. Siesling and W. H. van Harten

    Citation: BMC Cancer 2021 21:231

    Content type: Research article

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  11. A recent study found an influence of organized mammography screening programmes (MSPs) on geographical and temporal variation of mastectomy rates. We aimed to quantify the effect on the example of one of the c...

    Authors: Christian Herrmann, Rudolf Morant, Esther Walser, Mohsen Mousavi and Beat Thürlimann

    Citation: BMC Cancer 2021 21:229

    Content type: Research article

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  12. Although myelodysplastic syndrome (MDS), acute myeloid leukemia (AML), myeloproliferative neoplasms (MPN) – including chronic myeloid leukemia (CML) – and myelodysplastic/myeloproliferative neoplasms (MDS/MPN)...

    Authors: K. A. Mundt, L. D. Dell, P. Boffetta, E. M. Beckett, H. N. Lynch, V. J. Desai, C. K. Lin and W. J. Thompson

    Citation: BMC Cancer 2021 21:227

    Content type: Review

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  13. In Korea, where gastric cancer is highly prevalent, biennial endoscopy is recommended among individuals over 40. Even under regular screening, some are still diagnosed at advanced stages. We aimed to identify ...

    Authors: Joo Hyun Lim, Ji Hyun Song, Su Jin Chung, Goh Eun Chung and Joo Sung Kim

    Citation: BMC Cancer 2021 21:218

    Content type: Research article

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  14. Age-adjusted US total pediatric cancer incidence rates (TPCIR) rose 49% 1975–2015 for unknown reasons. Prenatal cannabis exposure has been linked with several pediatric cancers which together comprise the majo...

    Authors: Albert Stuart Reece and Gary Kenneth Hulse

    Citation: BMC Cancer 2021 21:197

    Content type: Research article

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  15. The goal of this study is to disclose the clinically significant genomic alterations in the Chinese and Western patients with intrahepatic cholangiocarcinoma.

    Authors: Shifeng Xu, Yuan Guo, Yanwu Zeng, Zhijian Song, Xiaodan Zhu, Ning Fan, Zhilei Zhang, Guibing Ren, Yunjin Zang and Wei Rao

    Citation: BMC Cancer 2021 21:152

    Content type: Research article

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  16. Vascular mimicry (VM) was associated with the prognosis of cancers. The aim of the study was to explore the association between VM and anticancer therapy response in patients with lung adenocarcinoma.

    Authors: Xuejun He, Jijun You, Haibing Ding, Zhisheng Zhang, Lin Cui, Xiaomei Shen, Xiaoxia Bian, Yanqing Liu and Jue Chen

    Citation: BMC Cancer 2021 21:132

    Content type: Research article

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  17. South Africa (SA) has experienced a rapid transition in the Human Development Index (HDI) over the past decade, which had an effect on the incidence and mortality rates of colorectal cancer (CRC). This study a...

    Authors: Lactatia Motsuku, Wenlong Carl Chen, Mazvita Molleen Muchengeti, Megan Naidoo, Tamlyn Mac Quene, Patricia Kellett, Matshediso Ivy Mohlala, Kathryn M. Chu and Elvira Singh

    Citation: BMC Cancer 2021 21:129

    Content type: Research article

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  18. Lung Cancer is the leading cause of cancer deaths in Aotearoa New Zealand. Māori communities in particular have higher incidence and mortality rates from Lung Cancer. Diagnosis of lung cancer at an early stage...

    Authors: Jacquie Kidd, Shemana Cassim, Anna Rolleston, Lynne Chepulis, Brendan Hokowhitu, Rawiri Keenan, Janice Wong, Melissa Firth, Karen Middleton, Denise Aitken and Ross Lawrenson

    Citation: BMC Cancer 2021 21:121

    Content type: Research article

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  19. Cervical cancer is a leading cancer and cause of premature death among women in Uganda aged 15 to 44 years. To address the increasing burden of cervical cancer in Uganda, the Ministry of Health has adopted sev...

    Authors: James Henry Obol, Sophia Lin, Mark James Obwolo, Reema Harrison and Robyn Richmond

    Citation: BMC Cancer 2021 21:110

    Content type: Research article

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  20. There is limited real-world safety information on palbociclib for treatment of advanced stage HR+/HER2- breast cancer.

    Authors: Daniel C. Beachler, Cynthia de Luise, Aziza Jamal-Allial, Ruihua Yin, Devon H. Taylor, Ayako Suzuki, James H. Lewis, James W. Freston and Stephan Lanes

    Citation: BMC Cancer 2021 21:97

    Content type: Research article

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  21. Small soft tissue masses are often falsely assumed to be benign and resected with failure to achieve tumor-free margins. Therefore, this study retrospectively investigated the distribution of histopathologic d...

    Authors: Felix G. Gassert, Florian T. Gassert, Katja Specht, Carolin Knebel, Ulrich Lenze, Marcus R. Makowski, Rüdiger von Eisenhart-Rothe, Alexandra S. Gersing and Klaus Woertler

    Citation: BMC Cancer 2021 21:93

    Content type: Research article

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  22. A high incidence of upper urinary tract urothelial carcinoma has been reported in the southwestern area of Taiwan, where arsenic water contamination was considered the main cause. However, there is no definite...

    Authors: Che-Wei Chang, Chien-Hui Ou, Chih-Chin Yu, Chi-Wen Lo, Chung-You Tsai, Pai-Yu Cheng, Yung-Tai Chen, Hsu-Che Huang, Chia-Chang Wu, Ching-Chia Li and Hsiang-Ying Lee

    Citation: BMC Cancer 2021 21:80

    Content type: Research article

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  23. Breast cancer is the second most common causes of women’s death, worldwide. Data on risk factors associated with female breast cancer in the Afghan population is very limited. The aim of our study was to ident...

    Authors: Zekrullah Baset, Jamshid Abdul-Ghafar, Yasmin Nadeem Parpio and Ahmed Maseh Haidary

    Citation: BMC Cancer 2021 21:71

    Content type: Research article

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  24. Use of statins is associated with a reduced risk of hepatocellular carcinoma (HCC). However, the effect of statin use on HCC recurrence is unclear. This study aimed to evaluate the effect of statin use on recu...

    Authors: Shih-Yu Yang, Chih-Chi Wang, Kuang-Den Chen, Yueh-Wei Liu, Chih-Che Lin, Ching-Hui Chuang, Yu-Chieh Tsai, Chih-Chien Yao, Yi-Hao Yen, Chang-Chun Hsiao, Tsung-Hui Hu and Ming-Chao Tsai

    Citation: BMC Cancer 2021 21:70

    Content type: Research article

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  25. In contrast to the rapid increase in thyroid cancer incidence, the mortality has remained low and stable over the last decades. In Ecuador, however, thyroid cancer mortality has increased. The objective of thi...

    Authors: Paola Solis-Pazmino, Jorge Salazar-Vega, Eddy Lincango-Naranjo, Cristhian Garcia, Gabriela Jaramillo Koupermann, Esteban Ortiz-Prado, Tannya Ledesma, Tatiana Rojas, Benjamin Alvarado-Mafla, Cesar Carcamo, Oscar J. Ponce and Juan P. Brito

    Citation: BMC Cancer 2021 21:42

    Content type: Research article

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  26. The Oral Care BC-trial reported that professional oral care (POC) reduces the incidence and severity of oral mucositis in patients receiving everolimus (EVE) and exemestane (EXE). However, the effect of POC on...

    Authors: Katsuhiko Nakatsukasa, Naoki Niikura, Kosuke Kashiwabara, Takeshi Amemiya, Ken-ichi Watanabe, Hironobu Hata, Yuichiro Kikawa, Naoki Taniike, Takashi Yamanaka, Sachiyo Mitsunaga, Kazuhiko Nakagami, Moriyasu Adachi, Naoto Kondo, Yasuyuki Shibuya, Naoki Hayashi, Mariko Naito…

    Citation: BMC Cancer 2021 21:34

    Content type: Research article

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  27. In Mainland China, advance directives (ADs) and end-of-life care for patients with tumours, especially patients with brain tumours who may have lost consciousness or the ability to speak at the early stage of ...

    Authors: Yixin Wang, Yongkang Zhang, Yang Hong, Ping Zeng, Zongtao Hu, Xiuli Xu and Hongzhi Wang

    Citation: BMC Cancer 2021 21:25

    Content type: Research article

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  28. Chronic obstructive pulmonary disease (COPD) and lung cancer are associated diseases. COPD is underdiagnosed and thus undertreated, but there is limited data on COPD diagnosis in the setting of lung cancer. We...

    Authors: Sophie Corriveau, Gregory R. Pond, Grace H. Tang and John R. Goffin

    Citation: BMC Cancer 2021 21:14

    Content type: Research article

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  29. To investigate the clinicopathological characteristics of head and neck small cell carcinoma (H&NSmCC) and identify prognostic factors on the basis of the Surveillance, Epidemiology and End Results (SEER) data...

    Authors: Chen-xi Yu, Feiluore Yibulayin, Lei Feng, Meng Wang, Meng-meng Lu, Yuan Luo, Hui Liu, Zhi-cheng Yang and Alimujiang Wushou

    Citation: BMC Cancer 2020 20:1208

    Content type: Research article

    Published on:

  30. Due to the increased risk of viral infection and the severe shortage of medical resources during the pandemic of COVID-19, most hospitals in the epidemic areas significantly reduced non-emergency admissions an...

    Authors: Songxiao Xu, Xiangdong Cheng, Zhiwen Pan, Qian Song, Yihong Wang, Juan Xiong, Yongyi Chen, Fan Fan, Jing Zhu, Wanying Wu, Xueying Deng, Yanpin Yu, Xiaohong Xu, Wenhu Chen, Tao Zhu, Yang Yu…

    Citation: BMC Cancer 2020 20:1194

    Content type: Research article

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  31. Organized breast and cervical cancer screening programme could only provide services at no cost for a fraction of socioeconomic-deprived women in China and other low-resource countries, however, little evidenc...

    Authors: Heling Bao, Limin Wang, Matthew Brown, Mei Zhang, Katherine Hunt, Jiangli Di, Zhenping Zhao, Shu Cong, Jing Fan, Liwen Fang and Linhong Wang

    Citation: BMC Cancer 2020 20:1191

    Content type: Research article

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  32. Tumor micro-angiogenesis and lymphangiogenesis are effective prognostic predictors in many solid malignancies. However, its role on Xp11.2 translocation RCC has not been fully elucidated. Herein, we purposed t...

    Authors: Wenliang Ma, Jun Yang, Ning Liu, Xiaohong Pu, Feng Qu, Linfeng Xu, Xiaozhi Zhao, Xiaogong Li, Gutian Zhang, Hongqian Guo, Dongmei Li and Weidong Gan

    Citation: BMC Cancer 2020 20:1182

    Content type: Research article

    Published on:

  33. Breast cancer (BC) is the most common malignancy in Latin American women, but with a wide variability with respect to their mortality. This study aims to estimate the mortality rates from BC in Peruvian women ...

    Authors: J. Smith Torres-Roman, Jose Fabian Martinez-Herrera, Greta Carioli, Jorge Ybaseta-Medina, Bryan Valcarcel, Joseph A. Pinto, Alfredo Aguilar, Katherine A. McGlynn and Carlo La Vecchia

    Citation: BMC Cancer 2020 20:1173

    Content type: Research article

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  34. The most common gender-specific malignancies are cancers of the breast and the prostate. In developing countries, cancer screening of all at risk is impractical because of healthcare resource limitations. Thus...

    Authors: Mahdieh Montazeri, Benyamin Hoseini, Neda Firouraghi, Fatemeh Kiani, Hosein Raouf-Mobini, Adele Biabangard, Ali Dadashi, Vahideh Zolfaghari, Leila Ahmadian, Saeid Eslami, Robert Bergquist, Nasser Bagheri and Behzad Kiani

    Citation: BMC Cancer 2020 20:1170

    Content type: Research article

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  35. Competing risk method has not been used in a large-scale prospective study to investigate whether increased levels of high-sensitivity C-reactive protein (hs-CRP) elevate the risk of primary liver cancer (PLC)...

    Authors: Sarah Tan Siyin, Tong Liu, Wenqiang Li, Nan Yao, Guoshuai Xu, Jun Qu and Yajun Chen

    Citation: BMC Cancer 2020 20:1168

    Content type: Research article

    Published on:

  36. Patients with relapsed or refractory peripheral T-cell lymphoma (R/R PTCL) treated with pralatrexate have previously shown superior overall survival (OS) compared to those who underwent conventional chemothera...

    Authors: Seonyoung Park, Ah-Young Kim, Hyeonseok Cho, Deborah Baik, Hankil Lee, Sunghwa Cho and Hye-Young Kang

    Citation: BMC Cancer 2020 20:1157

    Content type: Research article

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  37. Women with an advantaged socioeconomic position (SEP) have a higher risk of developing breast cancer (BC). The reasons for this association do not seem to be limited to reproductive factors and remain to be un...

    Authors: Eloïse Berger, Noële Maitre, Francesca Romana Mancini, Laura Baglietto, Vittorio Perduca, Hélène Colineaux, Sabina Sieri, Salvatore Panico, Carlotta Sacerdote, Rosario Tumino, Paolo Vineis, Marie-Christine Boutron-Ruault, Gianluca Severi, Raphaële Castagné and Cyrille Delpierre

    Citation: BMC Cancer 2020 20:1138

    Content type: Research article

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  38. While immune-checkpoint inhibitors (ICIs) have transformed the field of oncology for advanced-stage cancers, they can lead to serious immune toxicities. Several systematic reviews have evaluated the risk of im...

    Authors: Zahra Karimian, Sandra Mavoungou, Joe-Elie Salem, Florence Tubach and Agnès Dechartres

    Citation: BMC Cancer 2020 20:1128

    Content type: Research article

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  39. People are at a high risk of gastric cancer if their first-degree relatives suffered from atrophic gastritis (AG), intestinal metaplasia (IM), intraepithelial neoplasia (IEN), dysplasia (DYS), or gastric cance...

    Authors: Rui Wu, Cheng Yang, Lin Ji, Zhi-Ning Fan, Yu-Wen Tao and Qiang Zhan

    Citation: BMC Cancer 2020 20:1110

    Content type: Research article

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  40. The worldwide prevalence and incidence of neuroendocrine neoplasms (NEN) have been increasing recently, although few studies have analyzed data on the current situation of NENs in Japan. Here, the Japan Neuroe...

    Authors: Toshihiko Masui, Tetsuhide Ito, Izumi Komoto and Shinji Uemoto

    Citation: BMC Cancer 2020 20:1104

    Content type: Research article

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  41. Tumour subtype has a significant effect on bone metastasis in breast cancer, but population-based estimates of the prognosis of patients with bone metastases at breast cancer diagnosis are lacking. The aim of ...

    Authors: Xiao Li, Xiaoli Zhang, Jie Liu and Yinzhong Shen

    Citation: BMC Cancer 2020 20:1102

    Content type: Research article

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  42. Follow-up after curative surgery is increasingly recognized as an important component of breast cancer care. Although current guideline regulates the follow-ups, there are no relevant studies on the adherence ...

    Authors: Ran Feng, Jingfeng Jing, Xiaojun Zhang, Ming Li and Jinnan Gao

    Citation: BMC Cancer 2020 20:1098

    Content type: Research article

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  43. Cancer is widely recognized as a global public health problem. Breast, prostate, and cervical cancer are among the most frequent types in developing countries. Assessing their incidence and mortality by region...

    Authors: Juliana Alexandra Hernández Vargas, Paula Ximena Ramírez Barbosa, Ana Milena Gil Quijano, Ana María Valbuena, Lizbeth Acuña and Jaime Alberto González

    Citation: BMC Cancer 2020 20:1097

    Content type: Research article

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  44. The incidence of thyroid cancer (TC) has increased rapidly over the past few decades in Korea. This study investigated whether the TC epidemic has been driven by overdiagnosis.

    Authors: Hee-Yeon Kang, Ikhan Kim, Yeon-Yong Kim, Jinwook Bahk and Young-Ho Khang

    Citation: BMC Cancer 2020 20:1096

    Content type: Research article

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  45. A secondary malignancy is the most serious complication in lung cancer (LC) survivors. This study aimed to evaluate the clinicopathological features, predictable risk factors and survival of patients with LC w...

    Authors: Huabin Wang, Yin Yin, Ru Wang, Junbin Huang, Hongman Xue, Yucai Cheng, Lidan Zhang and Chun Chen

    Citation: BMC Cancer 2020 20:1081

    Content type: Research article

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  46. In recent years, the identification of genetic and phenotypic biomarkers of cancer for prevention, early diagnosis and patient stratification has been a main objective of research in the field. Different multi...

    Authors: J. C. Triviño, A. Ceba, E. Rubio-Solsona, D. Serra, I. Sanchez-Guiu, G. Ribas, R. Rosa, M. Cabo, L. Bernad, G. Pita, A. Gonzalez-Neira, G. Legarda, J. L. Diaz, A. García-Vigara, A. Martínez-Aspas, M. Escrig…

    Citation: BMC Cancer 2020 20:1079

    Content type: Research article

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