Epidemiology, prevention and public health

Section edited by Manami Inoue

This section aims to consider publications which focus on all aspects of cancer epidemiology including risk factors for disease initiation and development, social determinants, environmental, behavioural, and occupational correlates, and the impact of health policies, practices and interventions on the community.

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  1. Research article

    Reducing the socioeconomic gradient in uptake of the NHS bowel cancer screening Programme using a simplified supplementary information leaflet: a cluster-randomised trial

    Uptake of colorectal cancer screening is low in the English NHS Bowel Cancer Screening Programme (BCSP). Participation in screening is strongly associated with socioeconomic status. The aim of this study was t...

    Samuel G. Smith, Jane Wardle, Wendy Atkin, Rosalind Raine, Lesley M. McGregor, Gemma Vart, Steve Morris, Stephen W. Duffy, Susan Moss, Allan Hackshaw, Stephen Halloran, Ines Kralj-Hans, Rosemary Howe, Julia Snowball, Graham Handley, Richard F. Logan…

    BMC Cancer 2017 17:543

    Published on: 14 August 2017

  2. Research article

    Oncological outcomes in an Australian cohort according to the new prostate cancer grading groupings

    A new 5-tiered grading grouping system has recently been endorsed for reporting of prostate cancer (PCa) grade to better reflect escalating risk of progression and cancer death. While several validations of th...

    K. R. Beckmann, A. D. Vincent, M. E. O’Callaghan, P. Cohen, S. Chang, M. Borg, S. M. Evans, D. M. Roder and K. L. Moretti

    BMC Cancer 2017 17:537

    Published on: 10 August 2017

  3. Research article

    An analysis of 97 previously diagnosed de novo adult acute erythroid leukemia patients following the 2016 revision to World Health Organization classification

    The incidence of acute erythroid leukemia subtype (AEL) is rare, accounting for 5% of cases of acute myeloid leukemia (AML), and the outcome is dismal. However, in 2016 revision to the WHO classification, the ...

    Shaowei Qiu, Erlie Jiang, Hui Wei, Dong Lin, Guangji Zhang, Shuning Wei, Chunlin Zhou, Kaiqi Liu, Ying Wang, Bingcheng Liu, Yuntao Liu, Benfa Gong, Xiaoyuan Gong, Sizhou Feng, Yingchang Mi, Mingzhe Han…

    BMC Cancer 2017 17:534

    Published on: 9 August 2017

  4. Research article

    The cost-effectiveness of active surveillance compared to watchful waiting and radical prostatectomy for low risk localised prostate cancer

    Radical prostatectomy is the most common treatment for localised prostate cancer in New Zealand. Active surveillance was introduced to prevent overtreatment and reduce costs while preserving the option of radi...

    Chunhuan Lao, Richard Edlin, Paul Rouse, Charis Brown, Michael Holmes, Peter Gilling and Ross Lawrenson

    BMC Cancer 2017 17:529

    Published on: 8 August 2017

  5. Research article

    High prevalence of co-infection between human papillomavirus (HPV) 51 and 52 in Mexican population

    Human papillomavirus (HPV) is associated with the genesis of cervical carcinoma. The co-infection among HPV genotypes is frequent, but the clinical significance is controversial; in Mexico, the prevalence and ...

    Jazbet Gallegos-Bolaños, Jessica Alejandra Rivera-Domínguez, José Miguel Presno-Bernal and Rodolfo Daniel Cervantes-Villagrana

    BMC Cancer 2017 17:531

    Published on: 8 August 2017

  6. Research article

    Impact of comorbid conditions on participation in an organised colorectal cancer screening programme: a cross-sectional study

    There is controversy regarding how comorbidity impacts on colorectal cancer screening, especially in the context of organised programmes. The aim of this study is to assess the effect of comorbidities on parti...

    Carolina Guiriguet, Guillem Pera, Antoni Castells, Pere Toran, Jaume Grau, Irene Rivero, Andrea Buron, Francesc Macià, Carmen Vela-Vallespín, Mercedes Vilarrubí-Estrella and Mercedes Marzo-Castillejo

    BMC Cancer 2017 17:524

    Published on: 7 August 2017

  7. Research article

    Clinicopathological features and prognostic validity of WHO grading classification of SI-NENs

    The clinicopathological characteristics of small intestinal neuroendocrine neoplasms (SI-NENs) and the prognostic validity of WHO grading classification for SI-NENs are still unknown in Asian patients.

    Luohai Chen, Lin Zhou, Meng Zhang, Liang Shang, Panpan Zhang, Wei Wang, Cheng Fang, Jingnan Li, Tianming Xu, Huangying Tan, Pan Zhang, Meng Qiu, Xianjun Yu, Kaizhou Jin, Ye Chen, Huishan Chen…

    BMC Cancer 2017 17:521

    Published on: 4 August 2017

  8. Research article

    Frequency of Human papillomavirus in women attending cervical cancer screening program in Chile

    Human papillomavirus (HPV) is the etiological factor for cervical cancer and its precursor lesions. The characterization of HPV genotypes in preneoplastic lesions and cervical cancer c...

    Priscilla Brebi, Carmen Gloria Ili, Alejandra Andana, Doris Menzel, Jaime Lopez, Pablo Guzman, Angelica Melo, Kurt Buchegger and Juan C. Roa

    BMC Cancer 2017 17:518

    Published on: 3 August 2017

  9. Study protocol

    Novel approaches to the prediction, diagnosis and treatment of cardiac late effects in survivors of childhood cancer: a multi-centre observational study

    Anthracycline-induced cardiac toxicity is a cause of significant morbidity and early mortality in survivors of childhood cancer. Current strategies for predicting which children are at greatest risk for toxici...

    Amy Skitch, Seema Mital, Luc Mertens, Peter Liu, Paul Kantor, Lars Grosse-Wortmann, Cedric Manlhiot, Mark Greenberg and Paul C Nathan

    BMC Cancer 2017 17:519

    Published on: 3 August 2017

  10. Study protocol

    Long-term effects and psychological adjustment: study protocol of a large register-based study on quality of life among survivors of hematological malignancies

    Both incidence and survival rates of hematological cancers are increasing, leading to a growing number of survivors with specific late and long-term effects. However, relevant research in physical, psychologic...

    Peter Esser, Katharina Kuba, Heide Götze and Anja Mehnert

    BMC Cancer 2017 17:482

    Published on: 12 July 2017

  11. Research article

    High cancer mortality for US-born Latinos: evidence from California and Texas

    Latinos born in the US, 36 million, comprise 65% of all US Latinos. Yet their cancer experience is nearly always analyzed together with their foreign-born counterparts, 19 million, who constitute a steady infl...

    Paulo S. Pinheiro, Karen E. Callahan, Scarlett Lin Gomez, Rafael Marcos-Gragera, Taylor R. Cobb, Aina Roca-Barcelo and Amelie G. Ramirez

    BMC Cancer 2017 17:478

    Published on: 11 July 2017

  12. Study protocol

    Communication about uncertainty and hope: A randomized controlled trial assessing the efficacy of a communication skills training program for physicians caring for cancer patients

    Although previous studies have reported the efficacy of communication skills training (CST) programs, specific training addressing communication about uncertainty and hope in oncology has not yet been studied....

    Yves Libert, Livia Peternelj, Isabelle Bragard, Aurore Liénard, Isabelle Merckaert, Christine Reynaert and Darius Razavi

    BMC Cancer 2017 17:476

    Published on: 10 July 2017

  13. Research article

    Evolution of educational inequalities in site-specific cancer mortality among Belgian men between the 1990s and 2000s using a “fundamental cause” perspective

    According to the “fundamental cause” theory, emerging knowledge on health-enhancing behaviours and technologies results in health disparities. This study aims to assess (trends in) educational inequalities in ...

    Katrien Vanthomme, Hadewijch Vandenheede, Paulien Hagedoorn and Sylvie Gadeyne

    BMC Cancer 2017 17:470

    Published on: 5 July 2017

  14. Study protocol

    Effects of an interactive mHealth innovation for early detection of patient-reported symptom distress with focus on participatory care: protocol for a study based on prospective, randomised, controlled trials in patients with prostate and breast cancer

    Cancer patients are predominantly treated as out-patients and as they often experience difficult symptoms and side effects it is important to facilitate and improve patient-clinician communication to support s...

    Ann Langius-Eklöf, Marie-Therése Crafoord, Mats Christiansen, Maria Fjell and Kay Sundberg

    BMC Cancer 2017 17:466

    Published on: 4 July 2017

  15. Research article

    UDP-glucuronosyltransferases and biochemical recurrence in prostate cancer progression

    Uridine 5′-diphosphate-glucuronosyltransferase 2B (UGT2B) genes code for enzymes that catalyze the clearance of testosterone, dihydrotestosterone (DHT), and DHT metabolites in the prostate basal and luminal ti...

    Delores J. Grant, Zinan Chen, Lauren E. Howard, Emily Wiggins, Amanda De Hoedt, Adriana C. Vidal, Skyla T. Carney, Jill Squires, Clara E. Magyar, Jiaoti Huang and Stephen J. Freedland

    BMC Cancer 2017 17:463

    Published on: 3 July 2017

  16. Study protocol

    Development of a computer-tailored physical activity intervention for prostate and colorectal cancer patients and survivors: OncoActive

    Cancer and cancer treatment coincide with substantial negative physical, psychological and psychosocial problems. Physical activity (PA) can positively affect the negative effects of cancer and cancer treatmen...

    R. H. J. Golsteijn, C. Bolman, E. Volders, D. A. Peels, H. de Vries and L. Lechner

    BMC Cancer 2017 17:446

    Published on: 26 June 2017

  17. Study protocol

    Within-class differences in cancer risk for sulfonylurea treatments in patients with type 2 diabetes (ZODIAC-55) – a study protocol

    Patients with type 2 diabetes (T2D) are at increased risk for developing cancer. As approximately 8% of the world’s population is living with T2D, even a slight increase in cancer risk could result in an enorm...

    Dennis Schrijnders, Geertruida H. de Bock, Sebastiaan T. Houweling, Kornelis J. J. van Hateren, Klaas H. Groenier, Jeffrey A. Johnson, Henk J. G. Bilo, Nanne Kleefstra and Gijs W. D. Landman

    BMC Cancer 2017 17:444

    Published on: 23 June 2017

  18. Research article

    HPV and cofactors for invasive cervical cancer in Morocco: a multicentre case-control study

    Limited national information is available in Morocco on the prevalence and distribution of HPV-sub-types of cervical cancer and the role of other risk factors. The aim was to determine the frequency of HPV-sub...

    Mohamed Berraho, Afaf Amarti-Riffi, Mohammed El-Mzibri, Rachid Bezad, Noureddine Benjaafar, Abdelatif Benideer, Noureddine Matar, Zinab Qmichou, Naima Abda, Mohammed Attaleb, Kaoutar Znati, Hind El Fatemi, Karima Bendahhou, Majdouline Obtel, Abdelhai Filali Adib, Simone Mathoulin-Pelissier…

    BMC Cancer 2017 17:435

    Published on: 20 June 2017

  19. Study protocol

    Personalised informed choice on evidence and controversy on mammography screening: study protocol for a randomized controlled trial

    In Italy women aged 50–69 are invited for a population-based breast cancer (BC) screening. Physicians, policy makers and patients associations agree on the need to inform women about the benefits and harms in ...

    Anna Roberto, Cinzia Colombo, Giulia Candiani, Livia Giordano, Paola Mantellini, Eugenio Paci, Roberto Satolli, Mario Valenza and Paola Mosconi

    BMC Cancer 2017 17:429

    Published on: 19 June 2017

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