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Fig. 6 | BMC Cancer

Fig. 6

From: CYD0281, a Bcl-2 BH4 domain antagonist, inhibits tumor angiogenesis and breast cancer tumor growth

Fig. 6

CYD0281 impedes tumor growth and angiogenesis in the chick embryo chorioallantoic membrane (CAM) model in a concentration-dependent manner. A Representative images of breast cancer xenografts in CAM assay. Quantification of tumor volume (B) and microvessel density (MVD) (C) in tumor surface area. D Representative H&E stained tumor tissue sections of chick embryo CAM assay. Significant effect compared to the DMSO group: **P < 0.01 and ***P < 0.001. Scale bars: 1600 μm (A) and 50 μm (D)

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