Table 5 TRAEs in 26 converted patients
TRAEs | Any grade (n, %) | Grade1~2 (n, %) | Grade≥3 (n, %) |
|---|---|---|---|
Hypertension | 1 (3.8) | 0 (0) | 1 (3.8) |
Decreased appetite | 3 (11.5) | 3 (11.5) | 0 (0) |
Abdominal pain | 3 (11.5) | 3 (11.5) | 0 (0) |
Nausea | 2 (7.7) | 2 (7.7) | 0 (0) |
Elevated alanine aminotransferase, ALT | 16 (61.5) | 12 (46.2) | 4 (15.4) |
Elevated aspartate aminotransferase, AST | 19 (73.1) | 13 (50) | 6 (23.1) |
Elevated blood bilirubin | 13 (50) | 12 (46.2) | 1 (3.8) |
Hypothyroidism | 3 (11.5) | 3 (11.5) | 0 (0) |
Palmar-plantar erythrodyses-thesia syndrome | 2 (7.7) | 2 (7.7) | 0 (0) |
Fatigue | 1 (3.8) | 1 (3.8) | 0 (0) |
Low leucocyte amount | 3 (11.5) | 2 (7.7) | 1 (3.8) |
Neutrocytopenia | 1 (3.8) | 1 (3.8) | 0 (0) |
Thrombocytopenia | 7 (26.9) | 5 (19.2) | 2 (7.7) |
Oral mucositis | 1 (3.8) | 0 (0) | 1 (3.8) |
Rash | 1 (3.8) | 1 (3.8) | 0 (0) |
ICIs-associated myocarditis | 1 (3.8) | 0 (0) | 1 (3.8) |
RCCEP | 1 (3.8) | 1 (3.8) | 0 (0) |