Table2 Mean expression level of enzymes in three time points after PD-L1 stimulation
Enzymes | HL-60 cells | THP-1 cells | ||||||
|---|---|---|---|---|---|---|---|---|
control | Mean expression in 24 h ± SEM | Mean expression in 48 h ± SEM | Mean expression in 72 h ± SEM | control | Mean expression in 24 h ± SEM | Mean expression in 48 h ± SEM | Mean expression in 72 h ± SEM | |
HK-2 | 1 ± 0.05 | 0.97 ± 0.02 P value = 0.9 | 2.66 ± 0.05 P value = 0.0001 | 8.36 ± 0.2 P value = 0.0001 | 1 ± 0.05 | 1.05 ± 0.08 P value = 0.9 | 2.94 ± 0.1 P value = 0.006 | 9.24 ± 0.5 P value = 0.0001 |
G6PD | 1 ± 0.05 | 0.86 ± 0.04 P value = 0.98 | 6.52 ± 0.06 P value = 0.0001 | 14.88 ± 0.5 P value = 0.0001 | 1 ± 0.05 | 1.52 ± 0.04 P value = 0.01 | 1.12 ± 0.05 P value = 0.7 | 2.72 ± 0.1 P value = 0.0001 |
CPT1A | 1 ± 0.05 | 0.81 ± 0.04 P value = 0.8 | 2.01 ± 0.05 P value = 0.01 | 17.05 ± 0.3 P value = 0.0001 | 1 ± 0.05 | 1.04 ± 0.04 P value = 0.1 | 0.86 ± 0.04 P value = 0.9 | 11.16 ± 0.5 P value = 0.0001 |
ACC | 1 ± 0.05 | 0.75 ± 0.03 P value = 0.007 | 0.58 ± 0.02 P value = 0.0001 | 0.49 ± 0.02 P value = 0.0001 | 1 ± 0.05 | 0.48 ± 0.06 P value = 0.001 | 0.13 ± 0.06 P value = 0.0001 | 0.02 ± 0.002 P value = 0.0001 |
ATGL | 1 ± 0.05 | 0.95 ± 0.04 P value = 0.8 | 1.13 ± 0.04 P value = 0.27 | 0.76 ± 0.02 P value = 0.032 | 1 ± 0.05 | 1.09 ± 0.08 P value = 0.9 | 0.63 ± 0.05 P value = 0.1 | 1.29 ± 0.1 P value = 0.22 |