Fig. 3

KDM genes-related molecular subtypes in GC. A Correlations and prognostic relation of 24 KDMs in GCs. Prognostic impact of each gene was reflected by the circle size Favorable factors for overall survival is in green, while risk factors was in purple. The line between each gene represented the correlation among CRGs. Positive correlation was in red, while negative correlation was in blue. Prognostic impact was calculated by LogRank test and correlation between genes was evaluated by Paerson analysis. B Plot shows the NMF rank survey and the optimal rank for cluster is 3 in TCGA-STAD cohort. C Consensus heatmap in TCGA-STAD cohort was shown in setting rank as 3 in NMF algorithm. D Kaplan–Meier survival plot for overall survival in TCGA-STAD cohort is based on 3 KGRCs sorted by NMF algorithm. P value was calculated by LogRank test. E The distribution of clinical stages (Stage I-IV) in each KGRC. F Principal component analysis of three KGRCs in TCGA-STAD cohort. G The enrichment difference of biological pathways in three KGRCs was displayed in heatmap