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Table 2 E-cad protein expression in carcinoma tissues compared to the corresponding normal tissues

From: A comprehensive analysis of different types of databases reveals that CDH1 mRNA and E-cadherin protein are not downregulated in most carcinoma tissues and carcinoma cell lines

 

E-cad protein expressiona

Carcinoma type

Stage 1

Stage 2

Stage 3

Stage 4

Breast carcinoma

Unchanged (4)

Up (74)

Up (32)

--------------

Endometrial carcinoma

Up (74)

Up (8)

Up (15)

Unchanged (3)

Ovarian carcinoma

Up (2)

--------------

Up (75)

Up (16)

Lung carcinoma

Up (59)

UP (30)

Up (21)

--------------

Colorectal carcinoma

Unchanged (10)

Unchanged (39)

Unchanged (40)

Unchanged (8)

Head/Neck carcinoma

Down (7)

Unchanged (25)

Unchanged (30)

Unchanged (46)

Kidney carcinoma

Down (52)

Down (13)

Down (33)

Down (12)

Pancreatic carcinoma

Down (4)

Down (65)

Down (35)

Down (7)

  1. aNumbers in the parentheses are the number of samples in each disease stage. The number of normal samples used are: breast, 18; endometrium, 31; ovary, 25; lung, 59; colon, 10; head/neck, 7; kidney, 52; pancreas, 4. Data were obtained from the CPTAC via the UALCAN portal (http://ualcan.path.uab.edu/analysis-prot.html) and was analyzed using t-test on log2-spectral count ratios [37, 40]