Skip to main content
Fig. 3 | BMC Cancer

Fig. 3

From: A comprehensive analysis of different types of databases reveals that CDH1 mRNA and E-cadherin protein are not downregulated in most carcinoma tissues and carcinoma cell lines

Fig. 3

CDH1 mRNA is highly expressed in most carcinoma cell lines and is expressed at low levels in non-epithelial cancer cell lines. A, CDH1 mRNA is highly expressed in carcinoma cell lines but is expressed at low levels in non-epithelial cancer cell lines. B, CDH1 expression in breast cancer cell lines, shown as a representative of CDH mRNA expression in most carcinoma cell lines. C, CDH1 mRNA levels remain unchanged in most non-epithelial tumor tissues compared to the corresponding normal tissues (cancer name in black) except for skin cutaneous melanoma (SKCM) which demonstrated a significant downregulation (green; q < 0.01), and testicular germ cell tumor (TGCT) and thymoma (THYM) which demonstrated an upregulation of CDH1 mRNA compared to the corresponding normal tissues (red; q < 0.01). DLBCL, diffuse large B-cell lymphoma; GBM, glioblastoma multiforme; UVM, uveal melanoma; LAML, acute myeloid leukemia; LGG, brain lower grade glioma; MESO, mesothelioma; PCPG, pheochromocytoma and paraganglioma; SARC, sarcoma

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us