Fig. 4

RNA sequencing of WT31 or WT31_P5IV. RNA sequencing of cultured, sub-confluent WT31 and WT31_P5IV melanoma cells was performed. A A heatmap of the GOBP cell adhesion gene set (GO:0,007,155) for WT31 and WT31_P5IV melanoma is presented. The red colored bars present upregulated genes, whereas blue colored bars show downregulation. Genes symbols are written on the right side. Genes were filtered by an adjusted P value < 0.05 and logFC ≥ 1 or ≤ -1. Genes are also listed in Suppl. Table 2. B A heatmap of the GOBP regulation of cell adhesion gene set (GO:0,030,155) of WT31 and WT31_P5IV melanoma is shown. The red colored bars present upregulated genes, whereas blue colored bars show downregulation. Genes symbols are written on the right side. Genes were filtered by an adjusted P value < 0.05 and logFC ≥ 1 or ≤ -1. Genes are also listed in Suppl. Table 3. C A heatmap of integrin and disintegrin-like proteins of WT31 and WT31_P5IV melanoma is shown. The red colored bars present upregulated genes, whereas blue colored bars show downregulation. Genes symbols are written on the right side. Genes were filtered by an adjusted P value < 0.05 and logFC ≥ 1 or ≤ -1. Genes are also listed in Suppl. Table 4