Table 1 Univariate and multivariate analysis of biomarkers and other factors for PFS in advanced HGSOC patients

Age at diagnosis

(> 60 vs ≤ 60 years)

2.57 (1.66–3.98)

 < 0.0001

1.70 (1.07–2.70)

0.024

    BMI

(> 25 vs ≤ 25)

1.73 (1.14–2.61)

0.007

-

NS

    Peritoneal carcinomatosis

(Yes vs No)

2.28 (1.51–3.45)

0.0001

1.87 (1.23–2.85)

0.003

    sPD-L1

(> 0.42 vs ≤ 0.42 ng/mL)

3.01 (1.85–4.89)

 < 0.0001

2.23 (1.34–3.73)

0.002

    sPD-1

(> 2.48 vs ≤ 2.48 ng/mL)

1.62 (1.04–2.50)

0.02

-

NS

    sBTN3A1

(> 4.75 vs ≤ 4.75 ng/mL)

2.74 (1.75–4.30)

 < 0.0001

-

NS

    pan-sBTN3As

(> 13.06 vs ≤ 13.06 ng/mL)

2.53 (1.63–3.94)

 < 0.0001

-

NS

    sBTN2A1

(> 5.59 vs ≤ 5.59 ng/mL)

1.92 (1.22–3.03)

0.004

-

NS

    sBTLA

(> 2.78 vs ≤ 2.78 ng/mL)

2.18 (1.41–3.36)

0.0002

-

NS