Fig. 1From: Treatment benefit of upfront autologous stem cell transplantation for newly diagnosed multiple myeloma: a systematic review and meta-analysisStudy designs for this meta-analysis. RCT, randomized controlled trial; ASCT, autologous stem-cell transplantation; PICO, patient, intervention, comparison, and outcome; CR, complete response; PFS, progression-free survival; OS, overall survivalBack to article page