Fig. 4

Comparison of anti-ING1-peptide antibody levels between HDs and patients with solid cancers. A Serum antibody levels against the bING1-239 peptide were compared between HDs and patients with solid cancers. The levels examined by AlphaLISA are shown in a scatter dot plot. Horizontal lines represent the averages, and the error bars represent SDs as described in the legends of Fig. 2. The p value was calculated with Dunn’s multiple comparison tests following a Kruscal-Wallis test (p < 0.001). Data are summarized in Additional file 1: Table S3. B CRC detection using anti-bING1 peptide antibodies was assessed using ROC analysis. Numbers in the figures indicate cutoff values, sensitivity, specificity, and AUC value