Fig. 1

ATM haploinsufficiency promotes NB cell proliferation. A Western blotting analysis of total ATM. β-Tubulin was used as a loading control. Signal intensities of ATM bands were determined using ImageJ software and normalized using β Tubulin band intensity. B Cell proliferation and C colony formation assays of ATM haploinsufficient CHP-134 cells. Results are presented as the mean ± SD from three independent experiments. *p ≤ 0.05, **p ≤ 0.01, and ***p ≤ 0.001; two-tailed paired Student’s t-test. Corresponding uncropped full-length blots are included in Supplementary Materials