Skip to main content

Table 2 Subgroup analysis of progression-free survival (PFS)

From: Apatinib plus etoposide in pretreated patients with advanced triple-negative breast cancer: a phase II trial

Subgroup

Number of patients

n (%)

Median PFS, months

(95%CI)

All patients

40 (100%)

6.0 (3.8–8.2)

Liver metastasis

  

 Yes

9 (22.5%)

7.1 (3.8–10.3)

 No

31 (77.5%)

5.8 (3.1–8.4)

Lung metastasis

  

 Yes

9 (22.5%)

5.3 (3.0-7.6)

 No

31 (77.5%)

7.1 (5.0-9.2)

Bone metastasis

  

 Yes

13 (32.5%)

7.4 (3.9–10.9)

 No

27 (67.5%)

5.7 (4.2–7.2)

Prior taxane therapy

  

 Yes

24 (60.0%)

7.1 (5.0-9.1)

 No

16 (40.0%)

4.5 (0.8–8.1)

Prior anthracycline therapy

  

 Yes

32 (80.0%)

7.5 (4.3–10.7)

 No

8 (20.0%)

6.0 (3.3–8.7)

Prior platinum therapy

  

 Yes

20 (50.0%)

8.1 (5.2–11.0)

 No

20 (50.0%)

5.0 (3.8–6.2)

  1. CI: confidence interval