Fig. 4

Nuclear BAP-1 expression (nBAP-1) versus serUM-Px metastatic risk category. Of 12 available primary enucleations, four (33%) had low nuclear BAP-1 expression (associated with high metastatic risk) and eight (67%) had high expression (associated with low metastatic risk). (A) Sankey diagram showing the flow of classifications between nBAP-1 and serUM-Px category. (B) Metastasis-free survival curves for the same 12 patients, according to nBAP-1 status (left) and serUM-Px category (right). There were no metastatic events in the low and intermediate metastatic risk categories. For definition of the serUM-Px categories, see Table 2. Colored areas represent 95% confidence intervals