Table 2 Effects of the intervention on 6-minute walk test and lung function parameters
Follow-up time | ACBT | Acapella plus ACBT | EDP plus ACBT | Acapella plus ACBT vs. ACBT | EDP plus ACBT vs. ACBT | EDP plus ACBT vs. Acapella plus ACBT | ||||
|---|---|---|---|---|---|---|---|---|---|---|
Mean (SD) | Between-group difference for mean change from baseline (95% CI) ǂ | P-value ǂ | Between-group difference for mean change from baseline (95% CI) ǂ | P-value ǂ | Between-group difference for mean change from baseline (95% CI) ǂ | P-value ǂ | ||||
6MWT (m) | ||||||||||
Baseline | 536.40 (85.76) | 535.25 (68.41) | 538.23 (69.93) | - a | - | - | - | - | - | |
1 week | 428.68 (89.90) | 462.76 (75.37) | 477.75 (63.63) | 35.23 (19.30–51.16) | < 0.001 | 47.25 (31.56–62.93) | < 0.001 | 12.02 (-1.41–25.44) | 0.080 | |
1 month | 481.92 (76.63) | 515.72 (66.29) | 533.46 (64.86) | 34.96 (19.03–50.89) | < 0.001 | 49.72 (34.04–65.41) | < 0.001 | 14.76 (1.34–28.19) | 0.032 | |
FVC% of predicted | ||||||||||
Baseline | 98.40 (16.73) | 99.26 (15.83) | 99.34 (17.99) | - | - | - | - | - | - | |
1 week | 50.68 (12.85) | 65.54 (14.52) | 70.48 (13.48) | 14.00 (10.39–17.6) | < 0.001 | 18.86 (15.25–22.48) | < 0.001 | 4.87 (1.38–8.36) | 0.007 | |
1 month | 63.69 (12.24) | 78.46 (13.42) | 81.60 (12.94) | 13.91 (10.30–17.51) | < 0.001 | 16.96 (13.35–20.58) | < 0.001 | 3.06 (-0.43–6.55) | 0.087 | |
FEV1% of predicted | ||||||||||
Baseline | 94.21 (17.22) | 94.86 (15.63) | 94.96 (15.86) | - | - | - | - | - | - | |
1 week | 50.10 (13.12) | 64.11 (13.99) | 69.20 (12.94) | 13.35 (9.83–16.87) | < 0.001 | 18.35 (14.85–21.85) | < 0.001 | 5.00 (1.65–8.35) | 0.004 | |
1 month | 62.58 (12.49) | 76.42 (13.62) | 80.63 (12.23) | 13.19 (9.67–16.71) | < 0.001 | 17.30 (13.80–20.80) | < 0.001 | 4.11 (0.76–7.46) | 0.017 | |