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Table 3 Cox regression analysis revealed the risk factors for DSS in LAC patients

From: The effects of the prognostic biomarker SAAL1 on cancer growth and its association with the immune microenvironment in lung adenocarcinoma

Characteristics

N

Univariate analysis

Multivariate analysis

  

HR (95% CI)

P

HR (95% CI)

P

T stage

488

 

T1

168

Reference

   

T2

262

1.701 (1.085–2.668)

0.021

1.319 (0.738–2.359)

0.350

T3

43

2.846 (1.453–5.572)

0.002

2.771 (1.070–7.174)

0.036

T4

15

2.770 (1.061–7.230)

0.037

2.691 (0.822–8.811)

0.102

N stage

475

 

N0

327

Reference

   

N1

83

2.751 (1.808–4.185)

 < 0.001

2.669 (1.151–6.188)

0.022

N2

63

2.762 (1.698–4.493)

 < 0.001

2.605 (0.751–9.030)

0.131

N3

2

0.000 (0.000-Inf)

0.995

0.000 (0.000-Inf)

0.996

M stage

344

 

M0

323

Reference

   

M1

21

2.455 (1.269–4.749)

0.008

2.719 (1.127–6.555)

0.026

Pathologic stage

483

 

Stage I

277

Reference

   

Stage II

112

3.017 (1.931–4.715)

 < 0.001

1.033 (0.417–2.558)

0.945

Stage III

72

3.326 (2.028–5.457)

 < 0.001

0.988 (0.247–3.943)

0.986

Stage IV

22

4.632 (2.371–9.050)

 < 0.001

  

Gender

491

 

Female

262

Reference

   

Male

229

0.989 (0.687–1.424)

0.954

  

Age

481

 

 <  = 65

243

Reference

   

 > 65

238

1.013 (0.701–1.464)

0.944

  

SAAL1

491

 

Low

243

Reference

   

High

248

1.850 (1.270–2.696)

0.001

2.520 (1.559–4.073)

 < 0.001

  1. Note: LAC Lung adenocarcinoma, DSS Disease-specific survival