Skip to main content

Table 2 Cox regression analysis revealed the risk factors for OS in LAC patients

From: The effects of the prognostic biomarker SAAL1 on cancer growth and its association with the immune microenvironment in lung adenocarcinoma

Characteristics

N

Univariate analysis

Multivariate analysis

  

HR (95% CI)

P

HR (95% CI)

P

T stage

523

 

T1

175

Reference

   

T2

282

1.521 (1.068–2.166)

0.020

1.318 (0.830–2.092)

0.242

T3

47

2.937 (1.746–4.941)

 < 0.001

3.078 (1.525–6.214)

0.002

T4

19

3.326 (1.751–6.316)

 < 0.001

2.329 (1.040–5.219)

0.040

N stage

510

 

N0

343

Reference

   

N1

94

2.381 (1.695–3.346)

 < 0.001

2.436 (1.275–4.655)

0.007

N2

71

3.108 (2.136–4.521)

 < 0.001

2.270 (0.953–5.403)

0.064

N3

2

0.000 (0.000-Inf)

0.994

0.000 (0.000-Inf)

0.993

M stage

377

 

M0

352

Reference

   

M1

25

2.136 (1.248–3.653)

0.006

2.059 (0.944–4.492)

0.070

Pathologic stage

518

 

Stage I

290

Reference

   

Stage II

121

2.418 (1.691–3.457)

 < 0.001

0.979 (0.487–1.969)

0.954

Stage III

81

3.544 (2.437–5.154)

 < 0.001

1.342 (0.511–3.524)

0.550

Stage IV

26

3.790 (2.193–6.548)

 < 0.001

  

Gender

526

 

Female

280

Reference

   

Male

246

1.070 (0.803–1.426)

0.642

  

Age

516

 

 <  = 65

255

Reference

   

 > 65

261

1.223 (0.916–1.635)

0.172

  

SAAL1

526

 

Low

262

Reference

   

High

264

1.500 (1.123–2.005)

0.006

1.890 (1.314–2.719)

 < 0.001

  1. Note: LAC Lung adenocarcinoma, OS Overall survival