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Table 2 Differential expression analysis between ccRCC tumor tissue and normal tissue

From: Comprehensive analyses of A 12-metabolism-associated gene signature and its connection with tumor metastases in clear cell renal cell carcinoma

Gene ID

Log2FoldChange (Log2FC)

Log2CPM

P

FDR

Expression Trends

AK3

-1.45

6.36

8.20E-119

8.36E-117

Down

ENO2

3.21

7.52

3.69E-81

1.60E-79

Up

TYMS

2.08

4.77

3.77E-81

1.63E-79

Up

POMGNT2

-1.12

4.11

3.97E-75

1.44E-73

Down

PFKP

1.97

8.92

1.60E-68

4.66E-67

Up

ENPP3

4.59

8.06

3.59E-68

1.04E-66

Up

NNMT

3.94

9.48

7.84E-67

2.17E-65

Up

PLIN2

2.94

9.89

1.38E-53

2.36E-52

Up

GAPDH

1.48

11.98

3.35E-53

5.60E-52

Up

TRIB3

3.14

5.84

7.35E-49

1.02E-47

Up

RIMKLA

2.35

4.92

2.24E-44

2.56E-43

Up

HSD3B7

2.24

6.19

9.25E-42

9.28E-41

Up

ITPKB

-0.95

5.84

2.48E-35

1.89E-34

Down

PLOD1

1.34

8.14

2.49E-33

1.73E-32

Up

PLOD2

1.78

8.31

1.27E-31

8.18E-31

Up

LPIN3

1.57

5.38

1.01E-30

6.28E-30

Up

GMPPA

0.77

5.33

3.99E-25

1.88E-24

Up

PGK1

0.9

9.92

8.25E-25

3.84E-24

Up

S100A10

0.92

8.37

1.70E-23

7.45E-23

Up

RPS15

1.01

8.01

2.34E-22

9.68E-22

Up

SPTLC2

-0.67

6.84

2.34E-22

9.71E-22

Down

HYI

0.86

3.84

2.83E-19

1.01E-18

Up

GALNT14

1.12

7.77

7.19E-18

2.40E-17

Up

GUCY1A1

0.79

6.44

2.37E-13

6.25E-13

Up

MAN1A2

-0.4

6.1

1.24E-09

2.64E-09

Down

METAP1

-0.17

5.42

0.0006511

0.0009494

Down

GALNT7

-0.27

4.37

0.0017783

0.0025001

Down

  1. aThe differential expression analysis was calculated based on the TCGA-KIRC Counts data via “edgeR” R packages
  2. bExpression tread meant the changes in the expression of a particular gene in tumor tissue compared with normal tissue
  3. cFDR meant the expected percent of false predictions in the set of predictions
  4. dFDR below 0.01 was set as the threshold