Skip to main content
Fig. 10 | BMC Cancer

Fig. 10

From: Comprehensive analyses of A 12-metabolism-associated gene signature and its connection with tumor metastases in clear cell renal cell carcinoma

Fig. 10

Somatic variant analysis of the MAPS. A Comparison of tumor mutation burden (TMB) between the high and low-risk subgroups based on the MAPS. B Survival analysis of the different subgroups stratified by TMB. C Survival analysis of distinct subgroups stratified by both TMB and the MAPS. D-E Waterfall plot of common tumor somatic mutation in the high-risk subgroup and low-risk subgroup. F Top 5 differentially mutated genes between high- and low-risk subgroups. G Comparison of SETD2 mutated patients between the high- and the low-risk subgroups based on the MAPS. H The proportion of SETD2 mutated patients between the metastasis subgroup and the non-metastasis subgroup based on the MAPS. I the correlation between SETD2 and GALNT7, METAP1, ITPKB, and TRIB3 based on the TCGA-KIRC cohort. P was calculated via the two-tailed Mann–Whitney test (A), log-rank test (B and C), the χ.2 test (G and H) and Pearson's correlation coefficient(I). For panel A, *P < 0.05

Back to article page