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Table 4 Causal estimates for the association between smoking initiation and coffee consumption and ovarian cancer subtypes

From: Association of smoking, alcohol, and coffee consumption with the risk of ovarian cancer and prognosis: a mendelian randomization study

Exposures

Histological subtypes

OR (95%CI)

P value

Smoking initiation

High-grade serous

1.15 (1.00–1.33)

0.057

Smoking initiation

Low grade serous

1.43 (0.93–2.20)

0.104

Smoking initiation

Clear cell

1.24 (0.87–1.76)

0.231

Smoking initiation

Endometrioid

1.13 (0.86–1.48)

0.369

Smoking initiation

Invasive mucinous

0.92 (0.65–1.32)

0.667

Coffee consumption

High-grade serous

1.23 (0.84–1.81)

0.28

Coffee consumption

Low grade serous

1.00 (0.28–3.53)

0.998

Coffee consumption

Clear cell

2.02 (0.73–5.61)

0.178

Coffee consumption

Endometrioid

3.01 (1.50–6.04)

0.002

Coffee consumption

Invasive mucinous

1.15 (0.44–3.05)

0.77