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Table 4 Relative changes of abdominal fat and muscle composition in CRC patients with cachexia compared to other groups

From: Abdominal fat and muscle distributions in different stages of colorectal cancer

 

SM

IMAT

SAT

VAT

 

Univariate

Multivariate

Univariate

Multivariate

Univariate

Multivariate

Univariate

Multivariate

 

β

P

β

P

β

P

β

P

β

P

β

P

β

P

β

P

Age

-0.73

(-0.86,

-0.59)

< 0.001

-0.74

(-0.83,

-0.65)

< 0.001

0.20

(0.17,

-0.23)

< 0.001

0.20

(0.17,

0.23)

< 0.001

-0.40

(-0.66,

-0.14)

0.003

-0.37

(-0.62,

-0.12)

0.004

0.92

(0.60,

1.23)

< 0.001

0.91

(0.61,

1.21)

< 0.001

Sex

42.77

(40.64,

44.90)

< 0.001

43.15

(41.17,

45.12)

< 0.001

-1.35

(-2.04,

-0.67)

< 0.001

-1.21

(-1.87,

-0.56)

< 0.001

-33.38

(-38.95,

-27.81)

< 0.001

-33.01

(-38.62,

-27.39)

< 0.001

43.16

(36.41,

49.91)

< 0.001

42.63

(35.89, 49.36)

< 0.001

Healthy

5.23

(-0.92,

11.39)

0.095

9.25

(5.39,

13.11)

< 0.001

1.93

(0.54,

3.32)

0.006

2.29

(0.99,

3.59)

0.001

34.54

(23.05,

46.04)

< 0.001

28.84

(17.84,

39.83)

< 0.001

22.72

(8.73,

36.71)

0.001

31.31

(18.12,

44.51)

< 0.001

Polyp

12.24

(6.10,

18.41)

< 0.001

11.36

(7.52,

15.21)

< 0.001

2.07

(0.68,

3.46)

0.004

2.21

(0.91,

3.50)

0.001

34.72

(23.23,

46.22)

< 0.001

34.33

(23.38,

45.27)

< 0.001

42.81

(28.82,

56.80)

< 0.001

43.51

(30.36,

56.65)

< 0.001

Cancer

14.57

(8.12,

21,09)

< 0.001

7.76

(3.72,

11.80)

< 0.001

1.01

(-0.46,

2.48)

0.180

1.22

(-0.15,

2.60)

0.080

22.97

(11.00,

34.95)

< 0.001

27.54

(16.11,

38.98)

< 0.001

38.35

(23.77,

52.92)

< 0.001

32.57

(18.85,

46.29)

< 0.001

Cachexia

0.00

---

0.00

---

0.00

---

0.00

---

0.00

---

0.00

---

0.00

---

0.00

---

  1. Note: β(cm2); SAT: subcutaneous adipose tissue, VAT: visceral adipose tissue. IMAT: intramuscular adipose tissue; SM: skeletal muscle; M: male; F: female