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Table 1 Clinical and pathological features of 70 breast cancer patients in surgery

From: Relationship between tumor microbiota transcriptional activity and gene expression in breast cancer

 

ER+/HER2-

ER+/HER2+

ER-/HER2+

Triple

-negative

P value

subjects (n)

7

48

8

7

 

age at surgery (year)

48.9 ± 10.1

54.0 ± 8.4

53.9 ± 10.6

59.0 ± 11.5

 

P value

0.105 *

0.167 *

0.386 *

  

ER status (IHC)

+

+

-

-

 

PR status (IHC)

+

+

-

-

 

HER2 status (IHC)

-

+

+

-

 

lymph node

     

Positive (n)

5 (71%)

24 (50%)

5 (63%)

5 (71%)

0.497#

Negative (n)

2 (29%)

24 (50%)

3 (38%)

2 (29%)

 

Tumor size

    

0.943#

> 20 mm (n)

3 (43%)

21 (44%)

4 (50%)

4 (57%)

 

≦ 20 mm (n)

4 (57%)

27 (56%)

4 (50%)

3 (43%)

 

Histological grade

     

grade 1

0 (0%)

7 (15%)

1 (13%)

1 (14%)

0.153#

grade 2

4 (57%)

30 (63%)

2 (25%)

3 (43%)

 

grade 3

3 (43%)

11 (23%)

5 (63%)

3 (43%)

 
  1. ER+: ER-positive > 10% tumor cells; ER-: ER-positive < 10% tumor cells. PR+: PR positive > 10% tumor cells; PR-: PR-positive < 10% tumor cells. HER2+: HER2 positive > 10% tumor cells; HER2-: HER2 positive < 10% tumor cells; Data are means ± standard deviations or presented as number of patients (%). Percentages are calculated from the total number of patients with known values. * Student’s t test; p value: ER+/HER2- versus triple-negative; or ER+/HER2 + versus triple-negative; or ER-/HER2 + versus triple-negative; # chi-square test