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Fig. 5 | BMC Cancer

Fig. 5

From: DNMT3A low-expression is correlated to poor prognosis in childhood B-ALL and confers resistance to daunorubicin on leukemic cells

Fig. 5

Knock-out of DNMT3A gene increased resistance of Reh and 697 cell lines to DNR. IC50 of DNR significantly increased in DNMT3A-knockout cells (Independent-samples T test, P = 0.0201 in Reh cell line (a) and P = 0.0022 in 697 cell line (b)). The standard errors of the means are shown (n = 3 experiments for each drug concentration)

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