Skip to main content
Fig. 4 | BMC Cancer

Fig. 4

From: DNMT3A low-expression is correlated to poor prognosis in childhood B-ALL and confers resistance to daunorubicin on leukemic cells

Fig. 4

LentiCRISPR/Cas9 mediated editing of DNMT3A gene in Reh and 697 cell lines. a and b T7e1 assay analysis of specific sgRNA-mediated indels at DNMT3A locus in Reh and 697 cell lines separately. The lower migrating bands marking by a white arrow represent the disrupted gene alleles. c and d Expression of three DNMT3A protein variants was significantly reduced in Reh and 697 cell lines infected by DNMT3A-sgRNA lentivirus separately

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us